• Title/Summary/Keyword: Nonsteroidal Anti-inflammatory Drugs (NSAID)

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A Case Report on Functional Dyspepsia in a Fibromyalgia Patient with a History of Long-Term Nonsteroidal Anti-inflammatory Drugs (NSAIDs) Use (장기간 NSAIDs를 복용한 섬유근육통 환자의 기능성 소화불량 치험 1례)

  • Kim, Keum-ji;Cho, Soo-ho;Park, Ji-seon;Ko, Seok-jae;Park, Jae-woo
    • The Journal of Internal Korean Medicine
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    • v.40 no.6
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    • pp.1268-1277
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    • 2019
  • Objective: The purpose of this study was to report the effectiveness of Korean medicine in the treatment of functional dyspepsia in a fibromyalgia patient with a history of long-term NSAIDs use. Methods: The patient was diagnosed as a Soeumin, one of the four constitution types in Korean medicine, and treated with herbal medicines such as Seungyangikgibuja-tang and Pyeongjinsunjeom-san. Acupuncture and moxibustion treatment were also performed. The severity of symptoms was assessed using the Numerical Rating Scale (NRS) of epigastric pain, daily oral intake changes, the Korean Gastrointestinal Symptom Rating Scale (KGSRS), the Gastrointestinal Symptom Score (GIS), and the Functional Dyspepsia-Quality of Life (FD-QOL) score. Results: After treatment for 48 days, the severity of epigastric pain decreased from NRS 8 to NRS 0, and daily oral intake was increased. The KGSRS score decreased from 55 to 43, the GIS score was reduced from 18 to 10, and the FD-QOL score also decreased from 69 to 55. Conclusions: This study suggests that Korean medical treatment could be an effective option for treating functional dyspepsia in fibromyalgia patients with a history of long-term NSAIDs use.

Bleeding after Taking Dual Antiplatelets and NSAID Concurrently (항혈소판제와 비스테로이드성소염진통제의 동시 투약으로 인한 출혈 사례)

  • Seo, Jeongmin;Choi, Joonghyuk;Son, Pyoungwoo;Lee, Seungmin;Chae, Hyunwoo;Kang, Geunhyung;Ji, Eunhee
    • Korean Journal of Clinical Pharmacy
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    • v.28 no.3
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    • pp.250-253
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    • 2018
  • When stenting is applied to treat myocardial infarction, antiplatelet agents are administered to prevent thrombosis, which increases the risk of bleeding. Patients with myocardial infarction are also more likely to have osteoarthritis simultaneously, because both diseases occur frequently in elderly patients. Patients with osteoarthritis often use analgesics, especially nonsteroidal anti-inflammatory drugs (NSAIDs); hence, patients with both diseases use analgesics and antiplatelet agents simultaneously. The risk of bleeding increases with the use of antiplatelet agents and this is further increased when NSAIDs are added. We would like to report a case that reflects this situation. A 60-year-old man underwent stenting after ST-elevation myocardial infarction, and was treated with aspirin and clopidogrel. This patient also received a pelubiprofen prescription from another physician to treat osteoarthritis. After the patient took pelubiprofen twice, he found a bruise on his wrist and reported it to the pharmacist. It is unlikely that this is rare in community pharmacies, so pharmacists should pay careful attention to the concomitant administration of analgesics to patients receiving antiplatelet agents and should provide appropriate education to patients.