• Korean Journal of Occupational Health Nursing
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• v.18 no.1
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• pp.55-70
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• 2009

Purpose: This study was done to investigate the effect of non-smoking campaign for subway workers on their health behavior such as smoking, drinking, and exercise. Method: The study was done on the subjects of 112 male employees for 3 years from 2003 to 2005 working at the Seoul Metropolitan Rapid Transit Corporation. However, the subjects decreased to 105 in 2004 and 111 in 2005 due to work transfer. The data were obtained through administering questionnaires. The non-smoking campaign was done with health education using various strategies and methods by an administrator-in-charge assisted by the community health center. Results: Smoking rate and cigarette consumption decreased but there was no statistical significance. Smokers' frequency of drinking and exercise were higher than that of non-smokers, but there was no statistical significance. Conclusion: The result indicated the program was not effective to change the subjects' health behavior; therefore, tailored program considering the subjects is recommended.

• Journal of the Korean Society of Food Science and Nutrition
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• v.36 no.6
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• pp.708-719
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• 2007

Glutathione S-transferase genotypes GSTT1, GSTM1 and GSTP1 were characterized in 104 healthy male and female subjects and compared with parameters of oxidative stress at the level of DNA and lipids, with antioxidant enzymes, and with plasma antioxidants in smokers and non.smokers. Of the 104 subjects studied, 57.4% were GSTT1 present and 47.6% were GSTM1 present. The GSTP1 polymorphisms a and b were represented as follows: a/a, 75.5%; a/b, 21.6%; b/b type, 2.9%. The GSTT1 null genotype was associated with decreased glutathione in erythrocytes and elevated lymphocytes DNA damage. GST-Px was higher in GSTT1 null compared with GSTT1 present type. The homozygous GSTP1 genotype was not associated with any antioxidant status or DNA damage. The difference in plasma ${\alpha}$-carotene and erythrocytes GSH-Px and GST activities between smokers and non-smokers was detected in the GSTT1 null genotype. Plasma ${\gamma}$-tocopherol and ${\beta}$-carotene decreased significantly in smokers having GSTM1 null genotype. When GSTT1 and GSTM1 were combined, plasma lycopene and erythrocyte GST were reduced in smokers in both null types of these genes. As for GSTP1 genotype, plasma ${\alpha}$-carotene and erythrocytes GSH-Px decreased significantly in smokers with GSTP1 b/b, while erythrocytes GSH-Px activities decreased in smokers with GSTP1 a/b. The different ${\beta}$-carotene level between smokers and non-smokers was seen with both GSTP1 a/a and a/b genotype. It seems that polymorphisms in the phase II metabolizing enzyme glutathione S-transferase may be important determinants of commonly measured biomarkers.

• Health Policy and Management
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• v.30 no.4
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• pp.505-512
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• 2020

Background: In monitoring exposure to environmental smoke (ETS), biomarkers can overcome the subjectivity and inaccuracy of self-reporting measurements, and have the advantage of reflecting ETS exposure in all places. This study aims to evaluate the effectiveness of ETS exposure measurement using biomarkers such as urine cotinine. Methods: This study used the Korea National Health and Nutrition Survey data from 2009 to 2018. A total of 28,574 non-smokers with urine cotinine data were selected for the study. The cotinine concentration and ETS exposure rate using urine cotinine was estimated and then compared with the self-reporting measurements. The degree of agreement among measurements of ETS exposure was confirmed. Results: As a result of measuring ETS exposure with urine cotinine, 23,594 (83.8%) out of 28,574 subjects were classified as to exposure groups. This estimate differs significantly from measurements made by self-reporting. In addition, the average concentration of cotinine in non-smokers has decreased to a 10th level over the past 10 years. Based on the biomarker, the sensitivity of the self-reporting was 8.5%-29.0%, the specificity was 16.4%-19.5%, and the kappa value was 2.0%-5.8%. Conclusion: The findings of our study show that self-reporting measurement does not well reflect the extent to which non-smoker's exposure to smoking materials. Whereas cotinine concentration has decreased significantly over the past 10 years, the ETS exposure rate has not reduced. It strongly suggests the need for intervention in the group of non-smokers exposed to low concentrations of smoke. Therefore, an assessment using biomarkers such as cotinine-based measurement should be made in the Health Plan 2030.

• Tuberculosis and Respiratory Diseases
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• v.69 no.3
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• pp.177-183
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• 2010

Background: Smoking reduces pulmonary function and induces various lung diseases. Recently, the rate of emphysema detection has increased due to lung cancer screening with low-dose chest computed tomography (CT). The purpose of this study was to evaluate changes in lung function associated with emphysema in healthy smokers. Methods: One hundred and ninety one healthy smokers, who had undergone a low-dose chest CT (LDCT) scan as part of lung cancer screening and had revisited the health center after a median 23.9 months' time, were recruited into this study. The severity of emphysema was calculated by the direct observation of a radiologist and a pulmonologist indipendently. Longitudinal changes in lung function according to emphysema based on LDCT and type of smoker was analyzed. Results: Of the participants in this study, 25% of healthy smokers had emphysema, which was mild in severity, in older patients (p=0.003) and in heavy smokers (p<0.001). $FEV_1/FVC$ and FEF25-75% were decreased in current smokers with emphysema (p=0.001 and p=0.009, respectively) and without emphysema (p=0.001 and p=0.042). Although lung function was not decreased in ex-smokers without emphysema, $FEV_1/FVC$ and FEF25-75% were decreased in ex-smoker with emphysema (p=0.020 and p=0.010). Conclusion: Upon examination with LDCT, the prevalence of emphysema was higher in healthy smokers was than in non-smokers. Lung function was diminished in smokers with emphysema, in spite of former smoker.

• The Journal of Asian Finance, Economics and Business
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• v.1 no.2
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• pp.25-30
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• 2014

The small number of fusion research that addresses fear-appeal and self-efficacy in the effectiveness of warning labels cause the label is not clear, then the purpose of the study is the first to examine the effect of the combination of the message. With the experimental method, a total of 240 participants were smokers consist of Indonesian university students in the age range 18-23 years. Data obtained then processed with ANOVA statistical methods and Test T. The results are consistent with previous studies that the visual warning labels more effective than the textual warning labels alone. Results also suggest that a warning label should be both visual and textual messages combined with self-efficacy. Limitations, this study does not differentiate among smokers and non-smokers, in addition to the images are used only one type of disease, so that the research needs to be done to distinguish these factors.

• Journal of the Korean Society of School Health
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• v.32 no.2
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• pp.88-95
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• 2019

Purpose: The prevalence of binge drinking has increased among Korean adolescents in recent years. The purpose of this study was to determine the influencing factors of adolescent binge drinking. Methods: This was a secondary analysis of data from the 14th Korea Youth Risk Behavior Survey. For the present analysis, 5,203 binge drinkers (girls who drank 3 or more glasses of soju and boys who drank 5 or more in average on one occasion in the last 30 days) and 4,464 non-binge drinkers were selected. Results: Compared with the adolescents who had no experience buying alcoholic beverages, the adolescents who responded that it was easy or uneasy to buy alcoholic drinks were more likely to be a binge drinker. Also, compared with never smokers, ex-smokers and current smokers were more likely to be a binge drinker. Binge drinking was positively associated with skipping breakfast, subjective health, and feelings of sadness or hopeless. Conclusion: The findings of this study may be useful in developing binge drinking prevention programs for adolescents.

• Biomedical Science Letters
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• v.29 no.1
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• pp.34-40
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• 2023

Smoking is one of the three major risk factors for vascular disease along with hypertension and hyperlipidemia. It is true that smoking has a negative effect on the circulatory system, and the frequency of coronary artery disease and peripheral vascular disease is significantly increased in smokers. Many epidemiological studies report that smokers have an approximately two-fold increased risk of coronary artery disease compared to non-smokers. This study was designed to investigate the relationship between cerebral blood flow change and depression index after acute smoking. Cerebral blood flow tests were performed before and after smoking in 8 subjects. Changes in blood flow after smoking were correlated with the depression score and negatively correlated with the depression score. In particular, there was a strong correlation with changes in blood flow in anterior cerebral artery. It is well known that changes in blood flow after smoking have a negative effect. In addition, considering the study that smoking aggravates the symptoms of depression, it was found that smoking and depression are factors that negatively affect each other.

• Journal of Nutrition and Health
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• v.26 no.3
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• pp.313-324
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• 1993

Sister chromatid exchange(SCE) has recently become a common cytogenic assay system for detecting exposure to chemical mutagens and carcinogens. One application of SCE is the monitoring of populations believed to be exposed to such agents. A cross-sectional study of SCE frequency in peripheral blood lymphocytes from 40 college students aged 18 to 26 years was conducted. The effects of cigarette smoking alcohol and coffee consumption, dietary and environmental factors on SCE were assessed. A mean spontaneous SCE per cell for the smokers(4.88$\pm$0.17). The SCE levels of the smokers were associated with the personal smoking amount ; the observed increase in the SCE frequency correlated with the number of cigarettes smoked per day (P<0.05). There was no effect of age on SCE. There were positive linear relationship between SCE and food frequency score of meat and fish group (P<0.05) or instant food group(P<0.01) in non-smokers. But in smokers, a significant inverse association between SCE and food frequency score of green and yellow vegetable group(P<0.05). Alcohol intake produced a significant increase(P<0.01) of SCE in comparison with the mean SCE for those not drinking alcohol in combine subjects. Other dietary parameters, including coffee intake, use of artificial sweetners and processed foods, did not show any increase in SCE. SCEs were inversely related to blood glucose and serum cholesterol levels of the combine subjects. No significant correlations were found between SCE frequencise and any other hematological parameters of the subjects.

• Journal of Korean society of Dental Hygiene
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• v.15 no.5
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• pp.889-898
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• 2015

Objectives: The purpose of the study is to investigate the oral health-related quality of life (OHIP-14) according to smoking in the male workers in Gunsan. Methods: A self-reported questionnaire was completed by 460 male workers in Gunsan from April 13 to 30, 2015. Among 460 workers, smokers were 205 and nonsmokers were 255. The questionnaire included three questions of general characteristics of the subjects, four questions of subjective oral health, fourteen questions of OHIP, ten questions of sobriety test (AUDIT), and eight questions of smoking (Fagerstrom Test for Nicotine Dependence, FTND). Data were analyzed by frequency analysis, t-test, ANOVA, Pearson's correlation, and multiple regression analysis using IBM SPSS(Statistical Package for the Social Science) for Windows 20.0 program. Results: In the nonsmokers, there was a negative correlation between the alcohol consumption, dental health condition, tooth pain, gum bleeding, and halitosis. The higher OHIP in the smokers had the negative correlation with nicotine dependence, alcohol consumption, tooth pain, gum bleeding, and halitosis. In order to improve OHIP, smokers are encouraged to manage gum bleeding, and non-smokers to halitosis. Conclusions: In order to improve OHIP, cessation of smoking and alcohol consumption is very important and it can lead to improve the quality of life in the workers.

• Journal of Multimedia Information System
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• v.9 no.2
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• pp.137-144
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• 2022

This research aims to identify the relationship between visual perception and emotion by the types of fear responses elicited from warning images on cigarette packages as well as the effectiveness of the size of such images through questionnaires and eye-tracking experiments with twenty university students from the colleges based in Busan. The research distinguished and analyzed the warning images as rational appeals and emotional appeals by the degree of fear and disgust and the result concurred with the research conclusions of Maynard that people would naturally avoid eye contact when presented with a warning image on cigarette packages. Also, eye avoidance was highly identified with larger (75%) warning images. While the previous research mostly adopted the self-rated validation method, this research tried to make the methodology more objective by adopting both questionnaires and eye-tracking experiments. Through this research, authors contribute to finding effective warning images on cigarette packages in a way to increase public awareness of the dangers of smoking and discourage smoking. Further research is recommended to explore the effectiveness of using explicit images on cigarette packages by the types of smokers such as heavy smokers, normal smokers, and non-smokers.