• 한국환경보건학회지
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• 제41권4호
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• pp.259-267
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• 2015

Objectives: This study evaluated the regional and seasonal concentrations of ambient hazardous heavy metals in an industrial complex area in Daegu City. Methods: A total of 64 SPM (Suspended Particulate Matter) samples were collected in non-industrial and industrial areas during 2014 and were analyzed for hazardous heavy metals elements (As, Cd, Mn, Ni, Pb) with ICP after acid extraction. Results: SPM and hazardous heavy metals concentrations showed regional (industrial complex area>non-industrial complex area) and seasonal (spring, winter>fall, summer) variations. All of the hazardous heavy metals were influenced by anthropogenic sources. The pollution index of hazardous heavy metals was very low, showing roughly one-quarter of the level of the air quality guidelines of WHO. The correlation analysis among SPM and hazardous heavy metals indicated that components of non-industrial complex areas were more related to each other than those of industrial complex areas, and the correlation in the winter was higher than in other seasons. Conclusion: It is necessary to control air pollution sources and establish related policy because hazardous heavy metals from industrial areas can influence residential areas.

• Journal of Ginseng Research
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• 제19권3호
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• pp.212-218
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• 1995

A human hepatoma cell line, hep G2, was used to investigate the mechanism of serum cholesterol reduction by ginseng total saponin, ginsenoside-$Rb_1$, - $Rb_2$, and non-saponin fraction (ether extraction). Hep G2 cells were incubated in 10 $\mu\textrm{g}$/ml of cholesterol containing serum free-RPMl1640 medium with various concentration of ginseng components. The amounts of cholesterol in Hep G2 cells were decreased to maximum 51% in total saponin or two ginsenoside-treated groups while there was 137% increase in cholesterol level of control group as compared with that of normal group. Nonsaponin groups did not show the same effect. In order to elucidate the observed changes in the amount of cholesterol, the activity of amyl CoA : cholesterol acyltransferase (ACAT) in groups showing remarkable reduction in cholesterol amount, i.e., total saponin 10-6%, ginsenoside-$Rb_1$ $10^{-4}$%, ginsenoside-$Rb_2$, $10^{-4}$%, and non-saponin fraction $10^{-4}$%, was assayed using [1-$^{-14}C$%]oleic acid as enzyme substrate. The activity of ACAT was increased in all groups tested as compared with that of control group except for non-saponin group cultured in water soluble cholesterol containing medium. The serum cholesterol lowering effects of ginseng components can partially be attributed to the increased hepatocellular ACAT activity.

• 구강회복응용과학지
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• 제34권4호
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• pp.338-344
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• 2018

본 증례는 치주적으로 이환된 하악 전치부를 치은연상 치석제거술과 치근활택술을 포함한 비외과적 치주치료, 교합 조정 및 치아 간 치아고정술을 통해 회복한 경우이다 임상적, 방사선학적 평가를 술 후 1 - 3년간 시행하였다. 두 증례 모두 임상적 계측치에서 향상된 결과를 보였고 방사선학적 평가에서 현저한 치조골 및 치조백선의 재생이 관찰되었다. 이번 증례는 발치가 고려되는 심도의 치주질환에 이환된 치아에서 비외과적 치주치료와 치아고정술을 통해 치아를 보존할 수 있는 가능성을 보여준 사례로 보고하는 바이다.

• Smart Structures and Systems
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• 제30권1호
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• pp.75-88
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• 2022

Engineering structures in operation essentially belong to time-varying or nonlinear structures and the resultant response signals are usually non-stationary. For such time-varying structures, it is of great importance to extract time-dependent dynamic parameters from non-stationary response signals, which benefits structural health monitoring, safety assessment and vibration control. However, various traditional signal processing methods are unable to extract the embedded meaningful information. As a newly developed technique, variational mode decomposition (VMD) shows its superiority on signal decomposition, however, it still suffers two main problems. The foremost problem is that the number of modal components is required to be defined in advance. Another problem needs to be addressed is that VMD cannot effectively separate non-stationary signals composed of closely spaced or overlapped modes. As such, a new method named generalized adaptive variational modal decomposition (GAVMD) is proposed. In this new method, the number of component signals is adaptively estimated by an index of mean frequency, while the generalized demodulation algorithm is introduced to yield a generalized VMD that can decompose mode overlapped signals successfully. After that, synchrosqueezing wavelet transform (SWT) is applied to extract instantaneous frequencies (IFs) of the decomposed mono-component signals. To verify the validity and accuracy of the proposed method, three numerical examples and a steel cable with time-varying tension force are investigated. The results demonstrate that the proposed GAVMD method can decompose the multi-component signal with overlapped modes well and its combination with SWT enables a successful IF extraction of each individual component.

• 한방비만학회지
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• 제22권2호
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• pp.158-166
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• 2022

Objectives: The purpose of this meta-analysis was to evaluate the effects of berberine on non-alcoholic fatty liver disease (NAFLD) through a systematic review and meta-analysis. Methods: We searched seven electronic databases for studies through October 2022. All randomized controlled trials (RTCs) of berberine were included. Data extraction and risk of bias assessments were performed by two independent reviewers. The RevMan 5.4.1 program was used for meta-analysis. Results: A total of 279 relevant studies were identified, and 6 eligible RCTs were included to study the efficacy berberine on NAFLD. The six selected trials are studies on the effect between berberine and conventional treatment combined treatment versus conventional treatment. Liver function tests, blood lipid levels, and blood glucose levels were assessed. Combination treatment with berberine, ursodeoxycholate acid, metformin, and monascus purpureus showed statistically significant improvements in liver function levels, blood lipid levels, and blood glucose levels compared to conventional treatment alone. However, there was no significant efficacy of berberine combination dietary, exercise than control group on NAFLD. The meta-analysis results of examining 4 RCTs comparing the therapeutic efficacy of berberine showed statistically significant improvement in the liver function test, blood lipids levels, blood glucose levels. Conclusions: This study suggests that berberine has positive efficacy on blood lipids, blood glucose liver function, fatty liver condition of NAFLD. However, the level of evidence is low because of small effect size,so further investigation is needed.

• 한국정보통신학회논문지
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• 제26권11호
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• pp.1571-1576
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• 2022

코로나 바이러스의 발병 이후, 의료 산업은 침체기에 들어섰으며, 이에 대한 대응책으로 정부는 일시적으로 비대면 진료를 허용한 상태이다. 본 연구에서는, 이런 시대 흐름에 맞추어 의료 산업에 있어 현대인의 비대면 의학상담에 대한 관심도를 분석하고자 한다. 전문가에게 의학상담을 받을 수 있는 플랫폼인 지식인과, 유튜브 두가지 소셜 플랫폼에서 빅데이터를 수집해 연구를 진행했다. 전화 상담 상위 5개 키워드인 "내과", "일반의", "산경과", "정신건강의학과", "소아청소년과"와 더불어, "전문의", "의학상담", "건강정보" 총 8개의 검색어를 가지고 각 플랫폼으로부터 데이터 세트를 구축했다. 이후 크롤링 된 데이터를 바탕으로 형태소 분류, 질병 추출, 정규화 등 전처리 과정을 거쳤다. 단어 빈도수를 기준으로 한 워드 클라우드, 꺾은선 그래프, 분기별 그래프, 질병 등장 빈도별 막대 그래프 등으로 데이터 시각화를 하였다. 유튜브 데이터에 한해 감성 분류 모델을 구축하였고, GRU와 BERT 기반 모델의 성능을 비교하였다.

• Journal of information and communication convergence engineering
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• 제9권6호
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• pp.637-640
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• 2011

The hybrid neural networks have characteristics such as fast learning times, generality, and simplicity, and are mainly used to classify learning data and to model non-linear systems. The middle layer of a hybrid neural network clusters the learning vectors by grouping homogenous vectors in the same cluster. In the clustering procedure, the homogeneity between learning vectors is represented as the distance between the vectors. Therefore, if the distances between a learning vector and all vectors in a cluster are smaller than a given constant radius, the learning vector is added to the cluster. However, the usage of a constant radius in clustering is the primary source of errors and therefore decreases the recognition success rate. To improve the recognition success rate, we proposed the enhanced hybrid network that organizes the middle layer effectively by using the enhanced ART1 network adjusting the vigilance parameter dynamically according to the similarity between patterns. The results of experiments on a large number of calling card images showed that the proposed algorithm greatly improves the character extraction and recognition compared with conventional recognition algorithms.

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 2003년도 ICCAS
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• pp.2235-2239
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• 2003

The aim of this research is to study and develop enabling technologies for home healthcare device with ubiquitous network. The motivation of this paper is to enable healthcare in home, to development the device for smart home health care. To achieve the aim, we must develop the prototype platform based on home gateways, distributed context user interface based on UPnP and support for information sharing with high speed power line communication and mobile infra-structures. And IPv6 is the base technology of this platform. In this paper, we concern that physical health, mental health and medical emergencies is all of home healthcare. With the smart device, we evaluate the connectivity, automatic information extraction and private data exchange and event driven message. The result of this paper is demonstration of smart device for ubiquitous communication in a healthcare application such as patient monitoring device and several information services. In conclusion, home healthcare will support more healthy and easy living for a human.

• Bulletin of the Korean Chemical Society
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• 제25권7호
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• pp.1009-1011
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• 2004

In the present work a very simple, sensitive and selective spectrophotometric method for the determination of nitrite in micellar media is described. The method is based on the color reaction of nitrite with p-nitroaniline in the presence of diphenylamine in acid media. In order to remove the extraction step, Triton X-100, a non-ionic surfactant was used as micellar media. The optimum reaction conditions such as acid concentration, reagents concentration and effect of time have been studied and the analytical characteristics of the method such as limit of detection, linear range and molar absorptivity have been obtained. The interference of some anions and cations was also tested. The method was applied to the determination of nitrite in real samples.

• 정보기술과데이타베이스저널
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• 제6권1호
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• pp.89-101
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• 1999

Increasing number of companies recognize that the understanding of customers and their markets is indispensable for their survival and business success. The companies are rapidly increasing the amount of investments to develop customer databases which is the basis for the database marketing activities. Database marketing is closely related to data mining. Data mining is the non-trivial extraction of implicit, previously unknown and potentially useful knowledge or patterns from large data. Data mining applied to database marketing can make a great contribution to reinforce the company's competitiveness and sustainable competitive advantages. This paper develops the classification model to select the most responsible customers from the customer databases for telemarketing system and evaluates the performance of the developed model using LIFT measure. The model employs the decision tree algorithm, i.e., CHAID which is one of the well-known data mining techniques. This paper also represents the effective database marketing strategy by applying the data mining technique to a credit card company's telemarketing system.