• Journal of Korean Society of Archives and Records Management
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• v.7 no.2
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• pp.113-138
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• 2007

This study was started from a critical mind for the construction records management in South Korea and examined the state of the construction records management system of the Korea Rail Network Authority which is constructing the biggest Express Railway Construction of National Project in Korea. The Methodology of this study is based on the functional requirement of the Records Management International Standard, ISO 15489, which standardized the record management process in the cases of Record Capture, Declaration, Classification, Storage, Access, Tracking and Disposition. In regard to the functional requirements from Capture to Disposition, each level(title) consists of 3 to 4 items, for a total of 22 principles in all. The estimation was created for each of the 22 categories using 4 levels: observance, partial observance, insufficiency and non observance. And pointing out the problem, suggesting the improvements for the Korea Rail Network Authority and structural improvements according to the KS X ISO 15489 principles.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.36 no.1
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• pp.65-69
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• 2010

Collagen is the most abundant animal protein in mammals, accounting for about 30 % of all proteins. It is present in connective tissue and contributes to the structural framework of most organs. The tripeptide (glycineproline-hydroxyproline) with the INCI name Tripeptide-29 is main component of collagen type I. The palmitoyl tripeptide (palmitoyl-glycine-proline-hydroxyproline) with the INCI name Paimitoyi Tripeptide-29 is a synthetic material that was designed as a topical agent to stimulate collagen production. We synthesized the palmitoyl tripeptide as a potential anti-wrinkle compound. This compound has been characterized using HPLC. This compound proved, through in vitro tests, to stimulate collagen production and fibroblast proliferation. These results were very promising, so human studies were subsequently performed. We investigated the skin improvement effect of the palrnitoyl tripeptide on human skin by using non-invasive instruments. We measured physiological effects such as skin wrinkles and elasticity after volunteers applied the cosmetic products for 8 weeks. We observed significant improvement in skin wrinkles and elasticity after use of the cosmetic products for 8 weeks. We concluded that the palmitoyl tripeptide had an anti-aging effect on human facial skin.

• Polymer(Korea)
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• v.38 no.1
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• pp.85-92
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• 2014

To develop water-soluble chitosan as an effient gene delivery carrier, chitosan oligosaccharides (COSs) with various molecular weights (MW) were studied for gene transfection agents. MWs of COSs fractionated by ultrafiltration techniques were identified as narrow MW distributions with the average MW ranging from 1 to 10 kDa through gel permeation chromatography (GPC) measurement depending on the applied ultrafiltration membranes. Their structural characterizations were analyzed by FTIR spectrophotometer and $^1H$ NMR. The degree of deacetylation was determined by UV spectroscopy showing the degree of deacetylation above 90%. The relative cell viabilities were maintained over 100% (10 mg/mL), independent of the MW of the fractionated COSs. The fractionated COSs of 10 mg/mL concentration with narrow MW distributions showed non-cytotoxicity in Caco-2 cells.

• Nuclear Engineering and Technology
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• v.43 no.2
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• pp.149-158
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• 2011

Metal waste generated from the pyroprocessing of 10 MtU of spent fuel was classified by comparing the specific activity of a relevant radionuclide with the limit value of the specific activity specified in the Korean acceptance criteria for a lowand intermediate-level waste repository. A Korean Optimized Fuel Assembly design with a 17${\times}$17 array, an initial enrichment of 4.5 weight-percent, discharge burn-up of 55 GWD/MtU, and a 10-year cooling time was considered. Initially, the mass and volume of each structural component of the assembly were calculated in detail, and a source term analysis was subsequently performed using ORIGEN-S for these components. An activation cross-section library generated by the KENO-VI/ORIGEN-S module was utilized for top-end and bottom-end pieces. As a result, an Inconel grid plate, a SUS plenum spring, a SUS guide tube subpart, SUS top-end and bottom-end pieces, and an Inconel top-end leaf spring were determined to be unacceptable for the Gyeongju low- and intermediate-level waste repository, as these waste products exceeded the acceptance criteria. In contrast, a Zircaloy grid plate and guide tube can be placed in the Gyeongju repository. Non-contaminated Zircaloy cladding occupying 76% of the metal waste was found to have a lower level of specific activity than the limit value. However, Zircaloy cladding contaminated by fission products and actinides during the decladding process of pyroprocessing was revealed to have 52 and 2 times higher specific activity levels than the limit values for alpha and $^{90}Sr$, respectively. Finally, it was found that 88.7% of the metal waste from the 17${\times}$17 Korean Optimized Fuel Assembly design should be disposed of in a deep geological repository. Therefore, it can be summarized that separation technology with a higher decontamination factor for transuranics and strontium should be developed for the efficient management of metal waste resulting from pyroprocessing.

• Journal of The Korean Society of Agricultural Engineers
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• v.63 no.3
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• pp.97-105
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• 2021

Most of the rural development projects for the welfare of residents are mainly new construction and remodeling projects for community buildings such as village halls and senior citizens. However, in the case of the construction industry, it has been studied that 23% of the total carbon dioxide emissions generated in Korea are generated in the building-related sector. (GGIC, 2015) In order to reduce the emission of environmental pollutants resulting from construction of rural community buildings, there is a need to establish a system for rural buildings by predicting the environmental impact. As a result of this study, the emissions of air pollutants from buildings in rural communities were analyzed by dividing into seven stages: material production, construction, operation, maintenance, demolition, recycling, and transportation activities related to disposal. As a result, 12 kg of carbon dioxide (CO), 0.06 kg of carbon monoxide (CO), 0.02 kg of methane (CH), 0.04 kg of nitrogen oxides (NO), 0.02 kg of sulfurous acid gas (SO), and non-methane volatile organics per 1m of buildings in rural communities It was analyzed that 0.02 kg of compound (NMVOC) and 0.00011 kg of nitrous oxide (NO) were released. This study proved that environmentally friendly design is possible with a quantitative methodology for the comparison of operating energy and air pollutant emissions through the design specification change based on the statement of the rural community building. It is considered that it can function as basic data for further research by collecting major structural changes and materials of rural community buildings.

• Journal of Applied Biological Chemistry
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• v.64 no.4
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• pp.375-382
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• 2021

Biorenovation is a microbial enzyme-based structural modification of component compounds in natural products and synthetic compounds including plant extracts with the potential benefits of improved biological activities compared with its reaction substrates. In this study, we investigated the anti-inflammatory activity of Distylium racemosum leaf extract and D. racemosum leaf biorenovation extract (DLB). As a result, DLB inhibited nitric oxide, prostaglandin E2, and inflammatory cytokines including tumor necrosis factor-α, interleukin-6, interleukin-1β at non-toxic concentrations. In addition, DLB significantly inhibited inducible nitric oxide synthase and cyclooxygenase-2 on LPS-treated RAW 264.7 macrophages. Based on these results, we suggest that the DLB could be used as a potent anti-inflammatory agents. It also suggests that the application of biological evolution has potential usefulness to increase the practical value of natural products.

• Steel and Composite Structures
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• v.31 no.6
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• pp.601-615
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• 2019

In cold-formed steel (CFS) structures, such as trusses, wall frames and columns, the use of back-to-back built-up CFS angle sections are becoming increasingly popular. In such an arrangement, intermediate fasteners are required at discrete points along the length, preventing the angle-sections from buckling independently. Limited research is available in the literature on the axial strength of back-to-back built-up CFS angle sections. The issue is addressed herein. This paper presents the results of 16 experimental tests, conducted on back-to-back built-up CFS screw fastened angle sections under axial compression. A nonlinear finite element model is then described, which includes material non-linearity, geometric imperfections and explicit modelling of the intermediate fasteners. The finite element model was validated against the experimental test results. The validated finite element model was then used for the purpose of a parametric study comprising 66 models. The effect of fastener spacing on axial strength was investigated. Four different cross-sections and two different thicknesses were analyzed in the parametric study, varying the slenderness ratio of the built-up columns from 20 to 120. Axial strengths obtained from the experimental tests and finite element analysis were used to assess the performance of the current design guidelines as per the Direct Strength Method (DSM); obtained comparison showed that the DSM is over-conservative by 13% on average. This paper has therefore proposed improved design rules for the DSM and verified their accuracy against the finite element and test results of back-to-back built-up CFS angle sections under axial compression.

• Microbiology and Biotechnology Letters
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• v.46 no.4
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• pp.320-325
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• 2018

Hepatitis E virus (HEV) infection accounts for 20 million annual infections worldwide. HEV can be fatal in approximately 20-30% of pregnant women. HEV infections are normally self-limiting and mostly asymptomatic. However, in patients with insufficient immunity, such as acquired immunodeficiency syndrome patients, chronic and often fatal infections may ensue. Therefore, it is likely that host immune responses, especially interferon responses, play a critical role in HEV infection control. Here, we report that an HEV-encoded non-structural protein down-regulates type I interferon response. In addition, some other immune genes involved in the induction of type I interferon may be regulated as well. Detailed molecular mechanisms are currently being studied.

• The Journal of the Korea Contents Association
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• v.19 no.1
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• pp.587-597
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• 2019

With the rapid aging of the nation's population and the increasing number of elderly people with difficulties in daily life, the elderly care system was implemented for social solidarity. Structural problems in the long-term care system that emerged after the introduction of the system are demanded, and the problem of functional readjustment between nursing hospitals and facilities is raised due to the lack of continuity of care for the elderly by institutional and salary types. In this study, we set up research problems related to personnel, staff, and services to address the problem and conducted FGI. Research has shown that the number of elderly and recognized people in the region, the number of elderly and elderly patients, needs to be reflected in long-term care demand, the direction of appropriate institutional and manpower supply policies, and the establishment of local government goals and plans to strengthen the long-care institutions. It was revealed that non-medical accident arbitration bodies are needed to apply the cost of food insurance, provide programs through links with relevant institutions, and manage the admission smoothly.

• Journal of Ocean Engineering and Technology
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• v.32 no.6
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• pp.466-473
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• 2018

This paper presents an estimation method for the static configuration of a steel lazy wave riser (SLWR) using the dynamic relaxation method applied to estimate the configuration of structures with strong geometric non-linearity. The lumped mass model is introduced to reflect the flexible structural characteristics of the riser. In the lumped mass model, the tensions, shear forces, buoyancy, self-weights, and seabed reaction forces at nodal points are considered in order to find the static configuration of the SLWR. The dynamic relaxation method using a viscous damping formulation is applied to the static configuration analysis. Fictitious masses are defined at nodal points using the sum of the largest direct stiffness values of nodal points to ensure the numerical stability. Various case studies were performed according to the bending stiffness and size of the buoyancy module using the dynamic relaxation method. OrcaFlex was employed to validate the accuracy of the developed numerical method.