• Title/Summary/Keyword: No-Hoe Extract

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Eight Cases of Atopic Dermatitis treated with No-Hoe(蘆?: Aloe vera L.) Extract Dressing (蘆회 Dressing을 활용한 급성기 아토피피부염 환자 치험 8례)

  • Yoon, Hui-Sung;Lee, Gil-Young;Kim, Yoon-Bum
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.17 no.3
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    • pp.153-166
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    • 2004
  • In addition to antiseptic/antibiotic regimens, current therapies such as topical and systemic corticosteroids, anti-histamine agents, immune suppressing agent are generally used in the western medicine to treat atopic dermatitis(AD). However, there is almost a complete lack of effective strategies to achieve long-term control of disease, oriental medical treatments are proposed an alternative measure. It has been proved by experimental and clinical study that Oriental medical atopic dermatitis(AD) treatments such as herb-medicine, acupuncture and moxibustion therapy, and steam therapy are effective in long-term treatment. Nevertheless, oriental medical therapy has some limitations to treat acute stage of the disease. Recently developed No-Hoe(蘆?: Aloe vera L.) extract dressings will be a supplementary methods to the oriental medical therapy. The dressing can subside pruritus, exudation, erythema and scaling in the acute stage of atopic dermatitis(AD). We applied the No-Hoe(蘆?: Aloe vera L.) extract dressings to eight atopic dermatitis patients and got some good effects. This reports will provide an alternative choice for the oriental and westernal medical therapy for long-term AD treatment.

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The Effect of Mushroom Extract as a Dietary Additive on the Nutritive Quality of Cultured Olive Flounder Paralichthys olivaceus (양식산 넙치(Paralichthys olivaceus)의 식품학적 품질 개선에 버섯추출물이 미치는 영향)

  • Shim, Kil-Bo;Kim, Ji-Hoe;Yoon, Ho-Dong;Choi, Hae-Seung;Cho, Young-Je
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.44 no.6
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    • pp.785-790
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    • 2011
  • This study investigated the nutritive quality of olive flounder Paralichthys olivaceus fed either moist pellet (MP) or moist pellet mixed with mushroom extract (MPME) for 6 months. There was no significant difference in crude protein or extractive nitrogen in the muscle of flounder fed MP versus MPME (P > 0.05). The total amino acid content in the muscle of flounder fed MP was $15.22{\pm}5.24$ g/100 g, compared to $19.90{\pm}2.90$ g/100 g for flounder fed MPME. Essential amino acid content was $7.04{\pm}2.21$ g/100 g in the muscle of flounder fed MP versus $8.94{\pm}2.50$ g/100 g for MPME. Total amino acid content was higher in the muscle of olive flounder fed MPME, while essential amino acid content was higher in flounder fed MP. The ratio of non-essential amino acids to essential amino acids was $0.86{\pm}0.07$ for flounder fed MP and $0.81{\pm}0.08$ for flounder fed MPME. There was no significant difference in free amino acid content and fatty acid composition. The breaking strength of muscle of olive flounder fed MP was higher ($1.44{\pm}0.51\;kg/cm^2$) than in flounder fed MPME ($1.29{\pm}0.30\;kg/cm^2$). There was no evidence that dietary additives, such as mushroom extract, increase growth rate or nutritive quality of olive flounder.

Effect of Korean Mistletoe (Viscum album coloratum) Extract (KME) on the Extensions of Life span in Silkworm Moth, Bombyx Mori (누에 나방에 있어서 한국산 겨우살이(Viscum album coloratum) 추출물의 생명연장 효과)

  • Jung, Hoe-Yune;Lee, An-Na;Kim, Sae-Jung;Park, Sung-Min;Song, Tae-Jun;Ko, Byung-Woong;Kim, Young-Hoon;An, Hyo-Sun;Yoo, Yung-Choon;Min, Byeng-Ryel;Kim, Jong-Bae
    • Korean Journal of Pharmacognosy
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    • v.39 no.4
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    • pp.310-315
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    • 2008
  • Viscum album coloratum (Korean mistletoe; KM) is a semi-parasitic plant growing on various trees. This plant hasbeen shown to possess a variety of biological functions such as immunomodulation, apoptosis-induction and antitumor activity. However, there is no information about how the extract of KM affects life span of the host. In this study, in order to examine the effect of KM on the longevity of the host, we investigated whether a Korean mistletoe extract (KME) was able to extend the life length in an experimental model using the spring silkworm moth of Bombyx mori (Lepidoptera bombycidae). We established a model test for survival in which all of the male and female moths died within 18 days after the beginning of the experiment. Mean survival time of female moths was longer than that of male moths. Both male and female moths fed with KME containing diet (200 or 400 ${\mu}g$/head/day) showed significantly higher mean survival times than those of the control moths. Studying the effect of KME on prolongation of mean survival time showed that male moths were more susceptible than female moths. The moths fed with KME-containing diet showed a slight decrease in body weight. Interestingly, however, no difference in food intake was observed between moths fed with KME-containing diet and those with control diet. In analysis for mRNA increase in the SIRT2 gene, a member of the Sir2 gene family playing important roles in regulation of cell death and prolongation of life span, moths fed with KME-containing diet showed a significant increase in SIRT2 gene expression. These results suggest that KME has a potential to extend the life span in Bombyx mori, and its effect is partly associated with increase in SIRT2 gene expression.

Stability of Domoic Acid at Different Temperature, pH and Light (온도, pH 및 빛에 대한 Domoic Acid의 안정성)

  • Mok, Jong-Soo;Lee, Tae-Seek;Oh, Eun-Gyoung;Son, Kwang-Tae;Hwang, Hye-Jin;Kim, Ji-Hoe
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.42 no.1
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    • pp.8-14
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    • 2009
  • To prevent the food poisoning originated by consumption of shellfish contaminated with domoic acid, the quantitative analysis of domoic acid is to be very important. The stability of domoic acid at different temperature, pH and light was investigated using high performance liquid chromatography (HPLC). The mean recoveries of domoic acid in the methanol extracts from oyster (Crassostrea gigas), blue mussel (Mytilus edulis), short neck clam (Ruditapes philippinarum) and ark shell (Scapharca broughtonii) were 85.4-104.5%, 94.8-101.2%, 91.0-104.6%, and 95.7-109.6%, respectively. The working solutions of domoic acid standard were very stable for one month at $-18^{\circ}C$, $4^{\circ}C$, and room temperature. And domoic acid in the methanol extract from oyster was stable for a day at $4^{\circ}C$ and room temperature, and for a week at $-18^{\circ}C$. Therefore, this implies that quantitative analysis for domoic acid must consider the storage conditions of the standard solutions and the methanol extracts from shellfish. The standard solutions adjusted to pH 3-9 were also stable after heating at $121^{\circ}C$ for 30 min. The effect of light exposure on domoic acid was tested by exposing the methanol extracts to light. Domoic acid degraded slowly when the samples were kept in the dark (brown vial). However, following the light exposure the photodegradation became more rapid; no detectable domoic acid remained in $1.0{\mu}g/mL$ of methanol extract after 5 hours.

Antibacterial Activity of Sea-mustard, Laminaria japonica Extracts on the Cariogenic Bacteria, Streptococcus mutans (충치균 (Streptococcus mutans)에 대한 다시마 추출물의 항균활성)

  • Kim Ji Hoe;Lee Doo Seog;Lim Chi Won;Park Hee Yeon;Park Jeong Heum
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.35 no.2
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    • pp.191-195
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    • 2002
  • In previous reports the authors have screened the inhibition effects of marine algae extracts on halitosis, and demonstrated that a brown algae, Eisenia bicyclis (' Daehwang') possess not only strong deodorant effect bug also considerable anticariogenic activities. In this study, we screened antibacterial effects of various marine algae, and measured minimum inhibitory concentration (MIC) value of them against mutans streptococci in vitro. Among the 27 species of marine algae, $80\%$ ethanol extract of dried sea-mustard, Laminaria japonica ('Dasima') showed the strongest inhibition activity against Streptococcus mutans KCTC 3300. The extracts of Ulva lactuca ('Galparae'), Codium fragile ('Cheonggak'), Ecklonia cava ('Gamtae'), E. stolonifera ('Gompi') and Undalia Pinnatifida ('Miyeok') showed slightly weaker inhibitory potency than L. japonica. Differences of MIC values in $80\%$ ethanol extract of some species of marine algae were observed depending on test bacterial species, i.e., S. mutans KCTC 3300 or S. sobrinus KCTC 3307. Eighty percent ethanol extract of dried L japonica was fractionated with diethyl ether, chloroform, ethyl acetate, n-buthanol and water successively, The ether-soluble fraction had inhibitory effect on S. mutans KCTC 3300, however the inhibitory effects were not found in the other fractions. The MIC values of $80\%$ ethanol extract and ether fraction were 180 and 105 $\mu$g/mL respectively, while no significant inhibition activity of water-soluble fraction was found even when the fraction was added up to 5,500 $\mu$g/mL.

High-Performance Liquid Chromatographic Quantification of Flavonol Glycosides in Orostachys Species

  • Nugroho, Agung;Kim, Myung-Hoe;Han, Yu-Ran;Choi, Jae-Sue;Park, Hee-Juhn
    • Natural Product Sciences
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    • v.18 no.1
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    • pp.32-38
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    • 2012
  • The herbs of Orostachys japonicus (Crassulaceae) have been used to treat gastric cancer, gastric ulcer or hemorrhage. Flavonoid glycosides, mainly kaempferol (Kp)- and quercetin (Qc) glycosides, have been isolated from O. japonicus; however, no quantitative information on those flavonol glycosides and no peroxynitritescavenging activity of the Orostachys extracts have been reported. In this study, Kp- and Qc glycosides were qualitatively and quantitatively analyzed by high-performance liquid chromatography (HPLC) in eight Orostachys and a Meterostachys species including O. japonicas, O. margaritifolius, O. chongsunensis, O. minuta, O. ramosus, O. malacophylla, O. latiellipticus, O. iwarenge, O. iwarenge for. magnus, and Meterostachys sikokiana distributed or cultivated in Korea. Distinctively, O. margaritifolius contained two flavonol 3,7-di-O-glycosides of Kp 3,7-di-O-glucoside and Kp 3-rhamnosyl-7-glucoside, but O. japonicus had two flavonol 3-O-rutinosides, Kp 3-rutinoside and Qc 3-rutinoside. The three species of O. margaritifolius (24.36 mg/g MeOH extract), O. japonicus (21.28 mg/g), and O. minuta (19.50 mg/g) showed relatively higher flavonoid contents. The flavonol glycosides were analyzed using eight standard compounds (Kp, Qc, Qc 3-O-rhamnoside, Qc 3-O-glucoside, Kp 3- O-rutinoside, Qc 3-O-rutinoside, Kp 3-O-rhamnosyl-7-O-glucoside, Kp 3,7-di-O-glucoside). The present HPLC method was validated to verify the linearity, precision, and accuracy. In addition, the peroxynitrite-scavenging activity was also discussed.

Tetramine Contents of Sea Snails from the Korean Coast (한국 연안산 권패류의 tetramine 함량)

  • Mok, Jong-Soo;Son, Kwang-Tae;Lee, Tae-Seek;Oh, Eun-Gyoung;Hwang, Hye-Jin;Kim, Ji-Hoe
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.40 no.2
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    • pp.63-67
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    • 2007
  • To prevent food poisoning after ingesting sea snails containing tetramine we measured the tetramine $[(CH_3){_4}N^+]$ contents of sea snails from the Korean coast using both ion chromatography (IC) and spectrometry. In total, 177 sea snails were collected from the east (Pohang, 19 species, 95 individuals), the west (Gunsan, 4 species, 46 individuals), and the south (Tongyeong, 8 species, 36 individuals) coasts. The working solution of tetramine standard for IC and the tetramine extract from the salivary gland of Neptunea arthritica cumingii were very stable for one month at $18^{\circ}C,\;4^{\circ}C$, and room temperature. The tetramine content was high in the salivary gland of Heptunea species such as N. intersculpta $(9,813{\mu}g/g)$, N. arthritica $(8,240{\mu}g/g)$, N. arthritica cumingii $(6,967{\mu}g/g)$, N. eulimata $(6,946{\mu}g/g)$, N. constricta $(5,965{\mu}g/g)$, and N, amianta $(4,502{\mu}g/g)$. The mid-gut gland and muscle contained small amounts of tetramine. The tetramine content was highest in the autumn, but no clear regional variations were observed.

Physiology Activity of Barley Leaf Using Different Drying Methods (건조방법을 달리한 보리 잎의 생리활성)

  • Park, Soo-Jin;Lee, Jea-Soon;Hoe, Young-Hoi;Moon, Eun-Young;Kang, Myung-Hwa
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.37 no.12
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    • pp.1627-1631
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    • 2008
  • This study was to analyze the physiology activity of barley leaf extract using different drying methods. Yield of RL (raw leaf) and barley leaves dried did not show significant difference by various drying methods. There was no significant difference in total phenolic content by dry method. However, total flavonoid content was high in HD (dried after heat treatments) barley leaf after RL. There was no significance in barley leaf dried by SD (dried in the shade), FD (vacuum freeze dried) and MW (dried by microwave) after the microwave. Superoxide dismutase-like activity was high over 90%: $95.6{\pm}0.3%$ in RL, $94.9{\pm}0.7%$ in HD barley leaf, $92.0{\pm}1.3%$ in SD barley leaf, $91.5{\pm}0.4%$ in FD barley leaf, and $92.5{\pm}0.2%$ in MW barley leaf using the microwave. Significantly higher antioxidant activity was shown as compared to the control group of sesamol ($88.426{\pm}0.802%$), tocopherol ($88.8{\pm}0.6%$), and BHT ($86.6{\pm}0.8%$). Also, except for RL and MW barley leaf, all showed over 80% peroxyl radical scavenging activity and over 90% inhibition rate of xanthine oxidase. The results of this study show that total phenolic content and total flavonoid content by dry method were dependent on the drying temperature with no impact on antioxidant activity.

Patulin Producing Capacity in Broth Culture Media of Penicillium crustosum Isolated from Korean Apple (국내산 사과로부터 분리된 Penicillium crustosum의 액상배지에서의 Patulin 생성능 평가)

  • Kim, Dong-Ho;Yun, Hye-Jeong;Lim, Sang-Yong;Baik, Sang-Ho;Jo, Min-Hoe;Kim, Sooh-Hun
    • Food Science and Preservation
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    • v.14 no.3
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    • pp.315-322
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    • 2007
  • The patulin producing capicity of Penicillium crustosum, an isolate from Korean apple, in various broth culture media, was investigated, and compared with patulin production by the standard strain P. griseofulvum(ATCC 46037). The maximal patulin production capacity of the P. griseofulvum ATCC 46037 was 2,029-2,829 ppm in 5-GYEP, SY and MEB broth media. The patulin-producing capacity of the isolated fungus(P. crustosum) attained 2,794 ppm in a 5-GYEP broth medium, but was only 324 and 11 ppm in SY and MEB media, respectively. There were no significant correlations between mycelial growth levels and patulin-producing ability in either P. crustosum or P. griseofulvum. The patulin production of P. griseofulvum was induced in the wide pH range of pH 3.0-11.0, while that of P. crustosum was induced in the acidic pH range pH 3.0-5.0. Patulin production levels were dependent on the carbon sources in the media and maximal patulin production by P. griseofulvum and P. crustosum was observed in media containing glycerol and fructose, respectively.

In vivo Toxicity and Immunoadjuvant Activity of Korean Mistletoe (Viscum album coloratum) Extract Fermented with Lactobacillus (한국산 겨우살이 유산균 발효 추출물의 독성 및 면역증강 효과)

  • Yoon, Taek-Joon;Yang, Woong-Suk;Park, Sung-Min;Jung, Hoe-Yune;Lee, An-Na;Jung, Jin-Hyuk;Kang, Tae-Bong;Yoo, Yung-Choon;Kim, Jong-Bae
    • Korean Journal of Food Science and Technology
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    • v.41 no.5
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    • pp.560-565
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    • 2009
  • In this study, Korean mistletoe extract (KM-110) was fermented with two strains of Lactobacillus (FKM-110) and then toxicity, lectin content, and immune activities were investigated. The lectin content of FKM-110 was about 53-71% lower than that of KM-110. When mice were subcutaneously administered with KM-110 and FKM-110, the $LD_{50}$ obtained for KM-110 treatment was 50-100 mg/kg as compared to 150-200 mg/mL for FKM-110. Each preparation stimulated macrophages directly and enhanced productivity of inflammatory cytokines such as TNF-${\alpha}$ and IL-$1{\beta}$. FKM-110 treatment resulted in lower cytokine production compared to KM-110. When mice were immunized with Keyhol limpet hemocyanin (KLH) antigen along with KM-110 or FKM-110 administration, higher antibody titers to KLH were observed in the KM-110 or FKM-110 groups compared to mice immunized with KLH alone, thereby showing no difference between KM-110 and FKM-110. Therefore, fermentation of Korean mistletoe extract with these Lactobacillus strains decreased toxicity in vivo while the enhancement of immune activity by KM-110 and FKM-110 was similar. These data suggest that KM-110 fermentation tended to decrease lectin content and in vivo toxicity. In addition, other components in the fermented mistletoe extract appear to stimulate immuno-adjuvant activity instead of lectin.