• International Journal of Aeronautical and Space Sciences
• /
• 제16권3호
• /
• pp.451-462
• /
• 2015

Safety is the first priority in civil aviation, and so the International Civil Aviation Organization (ICAO) has introduced and mandated the use of Safety Management Systems (SMS) by airlines, airports, air traffic services, aircraft maintenance organizations, and training organizations. The aircraft manufacturing industry is the last for which ICAO has mandated the implementation of SMS. Since SMS is a somewhat newer approach for most manufacturers in the aviation industry, they hardly believe in the value of implementing SMS. The management of safety risk characteristics that occur during early aircraft development stages and the systematic linkage that the safety risk has to do with an aircraft in service could have a significant influence on the safe operation and life cycle of the aircraft. This paper conducts a case analysis of the McDonnell Douglas MD-11 accident/incident to identify the root causes and safety risk levels, and also verified why aircraft manufacturing industry should begin to adopt SMS in order to prevent aircraft accident.

• Clinical and Experimental Pediatrics
• /
• 제60권4호
• /
• pp.99-105
• /
• 2017

Food allergy (FA) is a serious health problem, and severe FA such as food-induced anaphylaxis can often be life threatening. The incidence of FA has been increasing especially in children. They usually develop early in life and affect up to 10% of children. The 2 most common food allergens worldwide are milk and eggs, while the third one varies depending on the countries: peanuts in the United States and Switzerland, wheat in Germany and Japan, tree nuts in Spain, sesame in Israel, and walnuts in Korea. These common food allergens are different and difficult to identify because of differing study methodologies, population, geography, age, and dietary exposure patterns. The current management of FA relies on the strict avoidance of culprit allergens, the prompt treatment of allergic reactions, including epinephrine use for food-induced anaphylaxis, monitoring, and education to prevent further reactions. Newer approaches for tolerance induction to FA and FA immunotherapy have been under investigation but are not yet ready for real-world application. Thus, consistent and systematic education of patients, caregivers, and food-handling people is of primary importance for the management and prevention of FA reactions. This review assesses and compares IgE-mediated FA in children in Korea and other countries, with a focus on summarizing the prevalence, common triggers, and management of FA.

• 한국정밀공학회지
• /
• 제26권4호
• /
• pp.82-90
• /
• 2009

Pneumatic cylinder is one of the low cost actuation sources which have been applied in industrial and prosthetic application since it has a high power/weight ratio, a high-tension force and a long durability However, the control problems of pneumatic systems, oscillatory motion and compliance, have prevented their widespread use in advanced robotics. To overcome these shortcomings, a number of newer pneumatic actuators have been developed such as McKibben Muscle, Rubber Actuator and Pneumatic Artificial Muscle (PAM) Manipulators. In this paper, one solution for position control of a robot arm, which is driven by two pneumatic artificial muscles, is presented. However, some limitations still exist, such as a deterioration of the performance of transient response due to the changes in the external load of the robot arm. To overcome this problem, a switching algorithm of the control parameter using a learning vector quantization neural network (LVQNN) is proposed in this paper. This estimates the external load of the pneumatic artificial muscle manipulator. The effectiveness of the proposed control algorithm is demonstrated through experiments with different external working loads.

• 소성∙가공
• /
• 제22권8호
• /
• pp.442-449
• /
• 2013

The solenoid valve case of an 8-speed automatic transmission plays a role in maintaining the valve seal, which prevents an inflow of foreign substances into the transmission. The seal increases the reliability of the automatic transmission's performance. As a solution to pollution-related problems and to reduce fuel consumption, transmissions are being made with more gears to work more economically and have reduced fuel consumption. These newer transmission require greater dimensional tolerances and need to be manufactured with more precision. In the current study, the design of a multistage drawing considering both the product's height and limit draw ratio (LDR) of the material was performed using both a theoretical analysis and the expertise of industrial experts. The finite element modeling (FEM) simulation was performed using the commercial software, PAM-stamp, and tests of the dimensional measurements for a prototype were performed to verify the optimal progressive process.

• 한국염색가공학회지
• /
• 제5권4호
• /
• pp.79-91
• /
• 1993

The purpose of this study is to prepare the newer, more comfortable of urea-formaldehyde resin finished fabrics. The methods of this study are by making examinations and comparisons the relations between the thickness, fabrics counts, weight, moisture regain and crease recovery of cotton and viscose rayon fabrics caused by condition of urea-formaldehyde resin finishing and warm retaining ability and warm-cool sense. The analytic results of thermal character in state of fabrics material finished with urea-formaldehyde are as follows: 1. The warm retaining ability has no correlation with mixing ratio of resin but the increase of the warm retaining ability has correlation with the increase of concentration of urea-formaldehyde resin. 2. The result pf multiple regression analysis for effect of physical property according to the concentration of resin to the warm retaining ability revealed as below. As the weight, thickness and density increase and moisture regain decreases, the warm retaining ability increases. 3. The qmax value has no correlation with mixing ratio of resin but the increase of the qmax value has correlation with the increase of resin concentration. In the end, the effect of it promotes cool sense. 4. The result of multiple regression analysis for effect of physical property according to the concentration of resin to the qmax value revealed as below. As he weight and thickness increase, the qmax value decrease. But, as the density and crease recovery increase, the qmax value increase.

• 보건행정학회지
• /
• 제16권4호
• /
• pp.147-168
• /
• 2006

Technological innovation has been regarded as the core competence for the economic growth of individual, as well as organization and country. Pharmaceutical innovation, what we call new medicines, influence people's longevity and productivity by increasing output per hour worked. Therefore, using claims data on virtually all the drugs and diseases of over 550,000 people enrolled in National Health Insurance Program in Korea, we examined the impact of the vintage (original FDA and KFDA approval year) of drugs used to treat a patients from July 1st to December 31st in 2002 on the patient's mortality at the end of 2004, controlling for demographic characteristics(age and sex), utilization of medical services, and the nature and complexity of illness. We found that people using newer drugs are less likely to die at the end of 2004, conditional on covariates. The estimated mortality rates were declining with respect to drug vintage for 1970s, 1980s and 1990s and highly significant. In addition to estimating the model for the entire sample, we estimated the model separately for several disease categories classified by Korean Classification of Disease. Estimates of three drug vintage variables for subgroups of people with (1)neoplasms, (2)endocrine, nutritional and metabolic diseases, and (3)the diseases of circulatory system displayed similar patterns.

• Journal of Dairy Science and Biotechnology
• /
• 제18권1호
• /
• pp.47-60
• /
• 2000

Over decades of work, the probiotic research has grown rapidly with a number of new cultures, which is claimed a variety of benefit. However, many of the specific effects attributed to the ingestion of probiotics remain convoluted and scientifically unsubstantiated. Accordingly, the scientific community faces a greater challenge and must objectively seek cause and effect relationships for many potential and currently investigated probiotic species. Rational selection and design of probiotics remains an important challenge and will require a solid information about the physiology and genetics of candidate strains relevant to their intestinal roles, functional activities, and interaction of with other resident micro flora. As far as beneficial culture of lactic acid bacteria (LAB) is concerned, simple, cost-effective, and exact identification of candidate strains is of foremost importance among others. Until recently, the relatedness of bacterial isolates has been determined sorely by testing for one or several phenotyphic markers, using methods such as serotyping, phage-typing, biotyping, and so forth. However, there are problems in the use of many of these phenotype-based methods. In contrast, some of newer molecular typing methods involving the analysis of DNA offer many advantages over traditional techniques. These DNA-based methods have the greater discriminatory power than that of phenotypic procedures. This review focuses on the importance and the basis of molecular typing methods along with some considerations on de-sign and selection of probiotic culture for human consumption.

• Journal of Oral Medicine and Pain
• /
• 제42권1호
• /
• pp.20-24
• /
• 2017

Drug-induced gingival overgrowth (DIGO) is an adverse drug reaction mainly described with three types of commonly prescribed drugs, namely, calcium channel blockers (CCBs) (nifedipine, diltiazem, and verapamil), anti-convulsants (phenytoin), and immunosuppressive agents (cyclosporine). Numerous reports have associated gingival overgrowth with the newer generation of immunosuppressive agents (tacrolimus, sirolimus, and everolimus), and CCBs (amlodipine, felodipine, nicardipine, and manidipine). Especially, patients concomitantly medicated with an immunosuppressive agent and CCB have a higher DIGO chance. Dentists need to be aware of drugs that induce gingival overgrowth, the possibility of DIGO, and risk factors, and also prevent the progression of DIGO by early detection of DIGO, consultation about the drug change, and the maintenance of strict dental hygiene regimes.

• 대한전기학회:학술대회논문집
• /
• 대한전기학회 1998년도 하계학술대회 논문집 F
• /
• pp.1886-1891
• /
• 1998

Traction battery chargers are an integral part of the required charging infrastructure. EV charging systems are continuing to improve in design. The newer types are affecting power quality to a much lesser extent. High efficiency battery chargers are being designed and produced which form little or no harmonic distortion. In addition chargers are becoming smaller and lighter. This is due mainly to the fact that there are improvements in the power electronics industry, especially with respected to IGBTs. Lower costs are achieved by the reduction in price of the IGBTs, standard magnetic material and small cores for inductors and transformers. But electric vehicles occupy a relatively small market niche at present. Therefore with already existing power supply networks, establishment of EV infrastructure can safeguard the service value of present vehicle as well as ensure the ability to charge a significant number of such vehicle. In this paper, we surveyed the update charging technologies according to the conductive charging, inductive charging and fast charging. Then we suggested cost-optimized charging infrastructure in consideration of the economical, political and technical standpoint.

• Clinical and Experimental Reproductive Medicine
• /
• 제40권2호
• /
• pp.55-59
• /
• 2013

Endometriosis is defined as the presence of functional endometrial tissue outside the uterus, causing diverse progressive symptoms such as infertility, pelvic pain, and dysmenorrhea. Although endometriosis has been described since the 1800s, the mechanisms responsible for its pathogenesis and progression remain poorly understood. It is well established that endometriosis grows and regresses in an estrogen-dependent fashion and the disease can be effectively cured by definitive surgery. However, prolonged medical therapy may be needed in most of the cases since conservative surgery is usually performed especially in young women. This treatment modality is often associated with only partial relief and/or recurrence of the disease. In the present review, up-to-date findings on the treatment of endometriosis will be briefly summarized. The outcomes of surgery in patients with endometriosis will be reviewed in terms of pelvic pain relief as well as infertility treatment largely based on recent Cochrane reviews and clinical reports. The efficacy of newer drugs including aromatase inhibitor, anti-tumor necrosis factor-alpha, and dienogest will be also reviewed based on recent clinical studies.