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Dose-Independent Pharmacokinetics of a New Neuroprotective Agent for Ischemia-Reperfusion Damage, KR-31543, after Intravenous and Oral Administration to Rats: Hepatic and Intestinal First-Pass Effects

  • Lee, Mi-Hye;Lee, Dae-Young;Bae, Soo-Kyung;Kim, Eun-Jung;Kim, Yoon-Gyoon;Kim, Sun-Ok;Lee, Dong-Ha;Lim, Hong;Yoo, Sung-Eun
    • Proceedings of the PSK Conference
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    • 2003.04a
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    • pp.312.2-313
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    • 2003
  • The purpose of this study was to report dose-independent pharmacokinetics of KR-31543, a new neuroprotective agent for ischemia-reperfusion damage, after intravenous and oral administration and first-pass effects after intravenous. intraportal, intragastric, and intraduodenal administration in rats. After intravenous (10, 20 and 50 mg/kg) and oral (10, 20 and 50 mg/kg) administration, the pharmacokinetic parameters of KR-31543 were dose-independent. (omitted)

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A New Management Innovation Strategy Through 6sigma for R&D linked with TRIZ (개발분야의 6시그마와 TRIZ 연계를 통한 새로운 경영혁신 전략)

  • An, Young-Soo;Hwang, In-Keuk
    • Journal of Korean Society of Industrial and Systems Engineering
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    • v.32 no.3
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    • pp.178-187
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    • 2009
  • Six Sigma emphasizes KPI and establishes the present level as well as the goal level through statistical calculation and tries to achieve management innovation through process improvement. But in the area of new product development or service, sufficient data for statistical measurement may not be secured. On the other side, looking for contradictions through problem analysis, TRIZ is a methodology that stresses the process of solving these problems. TRIZ also has its own problems: it is hard to define its initial task, to objectify the measurement of effect, and to optimize the drawn out idea. The purpose of this report is to give a comprehensive understanding about each methodology (Sigma Six and TRIZ) through its analysis, to confirm the need of linking both methodologies, and to suggest a model for this linking process. Also, they will be verified through examples, and the synergy effect will be discussed.

Dactylospora glaucomarioides (Ascomycetes, Dactylosporaceae): A Lichenicolous Fungus New to South Korea

  • Joshi, Yogesh;Knudsen, Kerry;Wang, Xin Yu;Hur, Jae-Seoun
    • Mycobiology
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    • v.38 no.4
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    • pp.321-322
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    • 2010
  • The lichenicolous fungi flora of South Korea is poorly known. During recent field trips to various parts of South Korea and after an extensive examination of herbarium lichen specimens, we encountered a lichenicolous fungi growing over a thallus of the lichen Ochrolechia yasudae Vain., characterized by small black apothecia with mostly three-septate brown ascospores. It was identified as Dactylospora glaucomarioides. This is the first report of this lichenicolous fungus from South Korea. A taxonomic description and comments are presented.

Listeromyces New to Mainland China (중국대륙일신기록층(中國大陸一新記錄層)-의충포낭속 ( Listeromyces ))

  • MA, Li-guo;MA, Jian;ZHANG, Kai;ZHANG, Xiu-guo
    • 한국균학회소식:학술대회논문집
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    • 2009.10a
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    • pp.20-26
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    • 2009
  • Listeromyces insignis, a species new to Mainland China, is reported and illustrated based on the specimen collected from dead branches at Mount Yuelu, Hunan Povince. This is the first report of the genus Listeromyces in Mainland China. The examined specimen is deposited in the Herbarium of the Department of Plant Pathology, Shandong Agricultural University (HSAUP).

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New record of three aquatic species of Enchytraeidae (Annelida: Clitellata) from Korea

  • Lee, Jeounghee;Jung, Jongwoo
    • Journal of Species Research
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    • v.5 no.3
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    • pp.541-546
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    • 2016
  • Enchytraeidae is one of the largest groups in Clitellata. They are commonly found in soil and aquatic environments and play important roles in these ecosystems. It is not easy to study enchytraeid clitellates because of difficulty in distinguishing morphologies between closely related species. In Korea, 29 species have been reported in this family. Of these, 27 species are terrestrial and only two species are aquatic. Here, we report three aquatic enchytraeid species new to Korea: Fridericia glandifera Friend, 1913, Henlea montana Rota, 1994 and Marionina brendae Bretscher, 1899.

Five new records of ostracods (Crustacea) from Korea

  • Yoo, Hyunsu;Huyen, Pham Thi Minh;Karanovic, Ivana
    • Journal of Species Research
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    • v.6 no.spc
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    • pp.220-226
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    • 2017
  • We briefly report the observation of five ostracod species: Scottia birigida Smith, Matzke-Karasz, Kamiya and Ikeda, 2002; Codonocera mortenseni Poulsen, 1962; Pyrocypris noctiluca Kajiyama, 1912; Euconchoecia cf. chierchiae Muller, 1890; and E. pacifica Chavtur, 1976. All five species are new records of Korean ostracod fauna. Specimens were collected during the 2014-2016 Korean Indigenous Species project. For three species we also include mtCO1 sequences. Currently, there are 65 published reports of indigenous Korean ostracod species.

New Morphology of Conducting Polythiophene

  • Karim Mohammad Rezaul;Lee Chul-Jae;Kim Hee-Jin;Bhuiyan Md Tauhidul Islam;Lee Mu-Sang
    • Proceedings of the Polymer Society of Korea Conference
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    • 2006.10a
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    • pp.286-286
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    • 2006
  • We report on a fascinating morphology; giant spherical conducting polythiophene by the in-situ gamma radiation-induced chemical polymerization method. The resultant micron-size buckyball-shaped polymer structures were identified by high resolution transmission electron microscopy and scanning electron microscopy. Different characterizations e.g. Fourier transform infrared, x-ray diffraction, and x-ray photoelectron microscopy were utilized to prove that the new morphological conducting polythiophene was synthesized successfully by this novel method.

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New Records of Cold-Water Corals from Korea

  • Song, Jun-Im
    • Animal Systematics, Evolution and Diversity
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    • v.32 no.3
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    • pp.197-206
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    • 2016
  • Two cold-water coral taxa, Octocorallia in the class Anthozoa and Stylasteridae in the class Hydrozoa, were identified. Deep-water samples were collected in fishing nets at depths ranging between 20 and 200 m along the coasts of the East Sea in Korea from 1976 to 1993. The two species found in this study represent new records for Korea: Paragorgia arborea (Linnaeus, 1758) in the class Anthozoa, and Stylaster profundiporus Broch, 1936 in the class Hydrozoa. Two families, Paragorgiidae and Stylasteridae, are also newly recorded in Korea. Furthermore, the species name of another cold-water gorgonian species, Primnoa pacifica (Kinoshita, 1907) in the family Primnoidae, is amended in this report. The two newly recorded cold-water coral species from Korea are described in detail based on their morphological characteristics. Paragorgia arborea is characterized by its growth form, medulla and cortex, zooid dimorphism, canal system, and spicule composition. Stylaster profundiporus is distinguished by its external skeletal characteristics, such as the coordination of dactylopores and gastropores, presence or absence of gastrostyles and dactylostyles, cyclosystem orientation, ampullar position, gastropore tube shape, and coenosteal texture.

A New Record of Cymatium encausticum (Ranellidae: Tonnoidea: Gastropoda) from Korea

  • Lee, Jun-Hee;Lee, Sang-Hwa;Lee, Jong-Rak;Park, Joong-Ki
    • Animal Systematics, Evolution and Diversity
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    • v.28 no.3
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    • pp.212-214
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    • 2012
  • The Cymatium Roding, 1798 is a small- to large-sized marine gastropod genus. Three species has been reported thus far for Cymatium in the Korean waters. In general, Cymatium encausticum (Reeve, 1844) is known to occur in tropical seawaters including the Philippine Islands along with its congeners C. gutturnium, C. springsteeni, and C. exile. A single individual of the species was collected from Jejudo Island by SCUBA diving and morphological features were observed using a stereomicroscope. This is the first study to report the occurrence of Cymatium encausticum (Reeve, 1844) from the Korean waters, providing a detailed description of the species with the illustration for the shell morphology.

A New Report of Two Species of Pagurid Hermit Crabs (Crustacea: Decapoda: Anomura) from Korea

  • Jung, Jibom;Kim, Won
    • Animal Systematics, Evolution and Diversity
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    • v.30 no.1
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    • pp.9-15
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    • 2014
  • Pagurus undosus and Pagurus parvispina, collected from the East Sea by fishery trap, are newly recorded from Korean waters. Pagurus undosus is distinguished from other hermit crab by its right cheliped slightly elevated medially, and with broad ridge formed by deep depressions mesial and lateral to midline. Pagurus parvispina is distinguished from other hermit crab by its right cheliped covered with large spine and long tufts of setae. These species live in cold water areas and their geographical distribution is extended southwardly by the present study. A specimen of the former species, P. undosus, was found living in a shelter formed by a sponge, similar to that observed in Pagurus pectinatus. Descriptions and figures of these two species are provided in this paper. Currently, 27 species of the genus Pagurus are recorded in Korean fauna.