• Title/Summary/Keyword: New Aging

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Accelerating aging test of distribution lightning arresters (배전용 피뢰기의 가속열화시험)

  • 김주용;송일근;김찬영;이병성;문재덕
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2000.07a
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    • pp.596-598
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    • 2000
  • This paper presents a new accelerating aging test facility for distribution lightning arresters. Aging parameters of lightning arrester are moisture ingress, electrical stress and surge absorption and so on. In this system, we applied 13.2kV to 6 samples and controled temperature and humidity of chamber and measured leakage currents of the all samples. Also we developed accelerating aging cycle which consists of -35$^{\circ}C$∼90$^{\circ}C$ temperature and 40%∼90% humidity. Through the aging test we found out the leakage current of aged sample increases rapidly according to the temperature rising. Hereafter we can determine the replacement guide of leakage current for field operating arresters and condition assessment of aged samples through this aging test.

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Acid sphingomyelinase-mediated blood-brain barrier disruption in aging

  • Park, Min Hee;Jin, Hee Kyung;Bae, Jae-sung
    • BMB Reports
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    • v.52 no.2
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    • pp.111-112
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    • 2019
  • Although many studies have reported that the breakdown of the blood-brain barrier (BBB) represents one of the major pathological changes in aging, the mechanism underlying this process remains relatively unexplored. In this study, we described that acid sphingomyelinase (ASM) derived from endothelial cells plays a critical role in BBB disruption in aging. ASM levels were elevated in the brain endothelium and plasma of aged humans and mice, resulting in BBB leakage through an increase in caveolae-mediated transcytosis. Moreover, ASM caused damage to the caveolae-cytoskeleton via protein phosphatase 1-mediated ezrin/radixin/moesin dephosphorylation in primary mouse brain endothelial cells. Mice overexpressing brain endothelial cell-specific ASM exhibited acceleration of BBB impairment and neuronal dysfunction. However, genetic inhibition and endothelial specific knock-down of ASM in mice improved BBB disruption and neurocognitive impairment during aging. Results of this study revealed a novel role of ASM in the regulation of BBB integrity and neuronal function in aging, thus highlighting the potential of ASM as a new therapeutic target for anti-aging.

The Relationships between the Health Promotion Behavior, Family Resilience, Marital Communication, and Successful Aging of New Middle-aged in Rural Areas (농촌 지역 신중년의 건강증진행위, 가족탄력성, 부부의사소통 및 성공적노화의 관계)

  • Yang, Seung Kyoung;Noh, Joo Ri;Kim, Mi La
    • Journal of Korean Academy of Rural Health Nursing
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    • v.16 no.2
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    • pp.37-44
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    • 2021
  • Purpose: This study was to investigate relationships among health promotion behavior, family resilience, marital communication, and successful aging of the new middle-aged living in rural areas. Methods: Data collection was conducted from May 1 to June 20, 2021, participants were 119 adults aged 50~69 living in rural areas. The data were analyzed using the IBM SPSS/WIN 23.0 program for descriptive statistics, independent t-test, one way ANOVA, Pearson's correlation coefficient, and multiple regression. Results: As a result, factors influencing successful aging for the new middle-aged were avocation (β=-.27, p=.002.), family resilience (β=.24, p=.045), marital communication (β=.22, p=.023), gender (β=.19, p=.023), and the explanatory power of 31.0%. Conclusion: These results suggest that it is necessary to develop a program to strengthen personal avocation, family resilience, and marital communication.

Performance Evaluation of Polymer Insulator using Tracking Wheel and Multi-Aging Test (트래킹 휠과 복합열화시험에 의한 폴리머 애자의 성능 평가)

  • 조한구;안명상;한세원;허종철;이운용
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2000.07a
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    • pp.119-122
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    • 2000
  • Recently polymer insulators are being used for outdoor high voltage applications. Polymer insulators for transmission line have significant advantages over porcelain and glass insulators, especially for ultra-high voltage transmission lines. Their advantages are light weight, vandalism resistance and hydrophobicity. Polymer insulators are a relatively new technology, but their expected life is still unknown. Therefore these estimating technique are very important. Their life time is related to weathering and operating condition. Multi-aging test is requested because aging factor is occurred by multi-aging than unique aging. The aging test about polymer insulators have mainly carried out by IEC 61109. This paper presents multi-stress chamber experiments and tracking wheel test to examine the tracking and erosion performance of polymer insulator for transmission. Multi-stress testing is able to demonstrate deficiencies of polymer insulator materials and designs, including the nature of interfaces in insulation design. We have investigated IEC 61109 Annex C (5000h aging test) and CEA tracking wheel test as test methods of artificial accelerated aging. The aging degree of polymer insulator is estimated by leakage current, measurement of hydrophobicity degree, damage conditions of insulator surface, withstand voltage test etc.

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Parabiosis and Blood Exchange Techniques in Aging Research (개체병렬결합(parabiosis)실험모델과 혈액교환을 이용한 노화(aging)연구 분석)

  • Kyung Tae Chung
    • Journal of Life Science
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    • v.33 no.2
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    • pp.208-215
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    • 2023
  • In recent decades, the field of aging research has progressed from the genetic and cellular levels to in vivo models of blood exchange. Since genes capable of extending the lifespan in C. elegance have been reported, various potential target molecules have been discovered through genomics, proteomics, metabolomics, and transcriptomics. Accordingly, research on the interactions between target molecules has also been increasing. The parabiosis method, in which two experimental animals are surgically combined, was introduced, and a factor that could reverse the aging phenomenon was discovered using this method. The parabiosis method is used to find more accurate and effective aging-reversal factors that could exist in young blood. As more new evidence has been revealed, the parabiosis method has established a new paradigm for aging research. Moreover, a device capable of exchanging blood elaborately in laboratory animals was published in 2022 and presented new results necessary for aging reversal. Since GDF11, was reported, many other anti-aging candidates that are soluble factors in blood, such as β2m, TIMP2, VCAM1, Gpld1, and clusterin, have been discovered. In addition, mcicroglia cells and neuroinflammation have been directly proven to be aging factors. These latest research results were obtained by parabiosis, the newly designed device for plasmapheresis, and injecting young blood or conditioned blood methods. In this review, we discuss the latest research results using the device and young blood administration in old mice.

Development of Neighborhood Design Indicators for Supporting Casual Contacts and Meetings of Old Residents (노인의 접촉·만남을 지원해 주는 근린환경 디자인 지표개발)

  • Oh, Chan-Ohk;Kim, Soo-Young;Chang, Su-Jie
    • Korean Institute of Interior Design Journal
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    • v.23 no.2
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    • pp.30-39
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    • 2014
  • Korean society is running fast toward a super aging society. This means that new solutions for new problems of aged people are needed. An important area to prove is the aging-friendly neighborhood environments supporting casual contacts and meetings of old residents. This study attempts to suggest neighborhood design indicators which support casual contacts and meetings of old residents. The subjects were 24 professionals who had studied on housing environment for the elderly. They answered through the on-line questionnaire. The questionnaire consisted of items which evaluate the appropriateness of classification of neighborhood area and the indicators of each area using 5-points Likert scale. Also open questions asking adding or eliminating areas or indicator and other opinions were included. On the basis of these answers, the aging-friendly neighborhood design indicators supporting contacts and meetings of old residents was developed. They are consisted of 7 areas in neighborhood and 60 indicators. Those areas were semi-public residential area, commercial area, cultural & educational area, health & medical area, park & green area, walkway, and public traffic facilities. This would be used to design the neighborhood environments that are aging-friendly and facilitating casual contacts and meetings of all residents, especially old residents.

Anti-aging Effects of Sweroside Isolated from Nymphoides indica (어리연꽃으로부터 분리한 Sweroside의 항노화 효과)

  • Kim, You Ah;Kim, Dong Hee;Park, Chae Bin;Park, Tae Soon;Park, Byoung Jun
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.44 no.2
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    • pp.103-110
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    • 2018
  • To develop a new functional agent for cosmetics, we investigated the anti-aging activities in fibroblasts using sweroside isolated from Nymphoides indica. The anti-aging effect of sweroside was validated in CCD-986sk cells. Results showed that sweroside inhibited expressions of UVB-induced ROS and increased pro-collagen. Furthermore, sweroside had inhibited MMP-1 expression. Taken together, the results suggested that sweroside has considerable potential as a new cosmetics ingredient with an anti-aging effect.

A Study on Practicality of Condition Monitoring Method of Accelerated Thermal Aging CSPE (가속열화 된 CSPE 상태감시법 유효성 평가)

  • Lee, Jung-Hoon;Goo, Cheol-Soo;Kim, In-Yong;Shin, Yong-Deok
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.60 no.11
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    • pp.2088-2092
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    • 2011
  • The accelerated thermal aging of CSPE(chloro sulfonate polyethylene) of test cables were carried out for the period equal to 10, 20 and 30 years in air at $100^{\circ}C$, respectively. The CSPE cables(TAIHAN electric wire Co. Ltd) which installed in nuclear power plant for three years were used as starting materials. Condition monitering methods of the accelerated thermal aging of CSPE cables were estimated through indenter modulus and OIT(oxidation induction time) of IEC 62582, and those were newly estimated through volume electrical resistivity, ultrasound reflection time, density, FE-SEM(field emission scanning electron microscopy), XPS(x-ray photoelectron spectroscopy), EDS(energy dispersive spectroscopy), and WD-XRF(wavelength dispersive x-ray fluorescence). A new condition monitoring methods of the accelerated thermal aging of CSPE cables were generally coincident with trend of indenter modulus expect EDS, XPS and XRF. A volume electrical resistivity among new condition monitoring methods of the accelerated thermal aging of CSPE cables is excellent. It is considered that life-time of CSPE cable can be predicted through volume electrical resistivity, if CSPE jacket was aged for period such as more than 20 years.

A Study on the Change of Mechanical Property According to the Aging of Polymer Electrolyte Membrane (고분자전해질막의 노후화에 따른 기계적 특성 변화에 관한 연구)

  • KIM, SEUNGHWAN;EO, JUNWOO;SEO, YOUNGJIN;HWANG, CHULMIN;JUNG, YOUNGGUAN
    • Transactions of the Korean hydrogen and new energy society
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    • v.33 no.2
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    • pp.176-182
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    • 2022
  • Since the various characteristics of the polymer electrolyte membrane are not clearly identified, it is difficult to predict and design applications for various conditions. In this study, as a previous study on the aging of the polymer electrolyte membrane, a study was conducted on the change of mechanical properties according to the aging of the polymer electrolyte membrane. Through the tensile test of Nafion 117, the mechanical properties change due to aging was confirmed. As a result of the tensile test, it was confirmed that the aged Nafion 117 had reduced tensile strength. Through DSC measurement, aged Nafion confirmed that the glass transition temperature and enthalpy change were low, which is thought to be the effect of molecular motion and transition due to the lapse of time. The effect is thought to cause a difference in the amount of change in enthalpy, resulting in a difference in mechanical properties during tension.

Aging and Skin Aging (노화와 피부노화에 대한 고찰)

  • Nam Hae-jeong;Kim Yoon-bum
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.17 no.1
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    • pp.16-33
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    • 2004
  • In Oriental medicine, aging is just a natural process like change of seasons. Ancient Oriental people accepted it as a natural thing to be growing older and to die at last. The science of aging has advanced dramatically. In the last 2 decades, advances in genetics and molecular biology have led to extraordinary new understandings in how cells age, how apoptosis programs cells to die, and how neuroendocrinology plays a role in the lifespan of organisms. Today, the matter of primary concern about aging is a cellular and mitochondrial damage of human body induced by reactive oxygen species(ROS). The skin aging can be divided into two areas, intrinsic(chronologic)-aging and photo-aging. There are lots of photo damage about skin aging. The skin is increasingly exposed to ultraviolet(UV) irradiation in life. Therefore, the risk of photo-oxidative damage of the skin induced by reactive oxygen species(ROS) has increased substantially. Nowadays, many people believe that they can stop or at least delay the process of aging. There are lots of treatments that promise to slow the process of aging and the associated ailments. Many of these treatments, for example, exercise, Vit E, Vit C therapy, hormone therapy, restrict diet, are gradually being subjected to clinical trials. But in spite of all efforts, researches and investigations, there is no single method or treatment which is revealed to be truly effective for delaying progress of aging. Every methods insisted on effect for delaying aging process, has its dark side. All we can do is just keeping ourself healthy until the time of death.

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