• 구강회복응용과학지
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• 제17권2호
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• pp.107-112
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• 2001

The prosthodontic treatment of severely resorbed edentulous patients has been one of the frustrating areas due to extensive loss of tissues. The integrated neuromuscular balance among tongue, lip, and cheek is compromised. The retention, stability, and support are the three major factors to influence the clinical outcome. Fish described a denture as having three surface, with each surface playing an independent and important role in the over all fit, stability, and comfort of the denture. He recommended that the polished surface should be a series of inclines so that pressure from muscular activity will retain dentures. Within the denture space there is an area that has been termed the neutral zone. The neutral zone is that area in the mouth where, during function, the forces of the tongue pressing outward are neutralized by the forces of the cheeks and lips pressing inward. According to Jacobson and Krol, neuromuscular control interacts to provide retention and the relationship of polished surface of denture base to the surrounding muscular structure of orofacial capsule facilitates the stability and retention. This neutral zone concept has been demonstrated with various modification by a number of authors. The theory used to develop the denture base contours is based on the belief that the muscle should functionally mold not only the border but the entire polished surface. Lott and Walsh reported the clinical success on complete mandibular dentures with application of neutral zone concept. A number of studies demonstrated that denture stability and retention are more dependent on correct position of the teeth and correct contour of external surfaces of the denture in a severely resorbed alveolar ridge. This article presents a prosthodontic approach to treatment of a edentulous patient using neutral zone technique to improve the retention and stability of the prosthesis.

• Journal of Periodontal and Implant Science
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• 제25권3호
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• pp.648-658
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• 1995

The present study has been performed to evaluate the clinical, microbiological, biochemical and immunological parameters associated with the periodontal disease activity in adolescent periodontitis. 21 young adolescents with evidences of periodontal attachment loss participated in the study for upto 3 years of examination. Probing pocket depths and attachment levels of whole dentitions were annually recorded and 4 deepest pockets, with initial probing depth ${\geq}$ 4mm, were selected as the representative experimental sites of a patient. Sites experiencing attachment loss ${\geq}$ 1mm during the 3-year experimental period were designated as the active sites and these sites were examined for the microbiological and biochemical profiles at the time when attachment loss occurred. Microbiological assay included cultural studies and PerioScan for monitoring BANA(+) organisms(e.g. Porphyromonas gingivalis, Treponema denticola, Bacteriodes forsythus). Biochemical assay has been performed for monitoring GCF levels of neutral protease. Serum IgG and IgG2 titers against Porphyromonas gingivalis 381 were determined of a patients at the beginning and the end of the study, respectively for patient-based analysis. The results indicated that the parameters consisting of microbiological cultures and GCF neutral protease exhibited low association with the periodontal disease activity in adolescents. However, the specificity for microbiological culture of the selected periodontopathic organisms(Aa,Pg,Pi) were considerably high. Moreover, the clinical pameters such as bleeding on probing and presence of plaque as well as IgG levels against Pg at the baseline exminations were closely associated with the subsequent evidences of attachment loss during the whole experimental period(3-year).

• Tribology and Lubricants
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• 제19권1호
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• pp.31-35
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• 2003

This paper reports the studies on the wear-corrosion behavior of ductile cast iron in the various pH environments. In the variety of pH solutions, corrosion and wear-corrosion loss of GCD 600 were investigated. Also, the anodic polarization test of GCD 600 using potentiostat/galvanostat was carried out. And rubbed surface of GCD 60 using scanning electron micrographs after immersion and wear-corrosion test was examined in the environment of various pH values. The main results are as following In alkali zone, the wear-corrosion loss of GCD 600 increases, but corrosion loss decreases. The unevenness and crack of wear-corrosion surface in neutral zone becomes duller than that in alkali zone. As the corrosive environment is acidified, wear-corrosion behavior of GCD 600 with passing immersion time becomes sensitive.

• Bulletin of the Korean Chemical Society
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• 제26권8호
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• pp.1170-1176
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• 2005

The structures and conformations of ortho-, meta-, and para-methyl red (MR) upon proton gain and loss were studied by density functional calculations, and compared to methyl yellow for the effects of a carboxyl substitution. Internal hydrogen bonding causes the geometry of neutral o-MR planar, otherwise twist. Monoprotonated species of MR are planar where the proton is attached to $\beta$-azo nitrogen. This loses its azo character a bit, and shows strong delocalization characterized as a quinonoid canonical structure. Di-protonated species of MR is proved to hold two protons at the amino and $\alpha$-azo nitrogen atoms, and planar. It regains somewhat of its azo character, but still shows fairly delocalized property in terms of carbocationic canonical structures. The carboxyl substitution on 4-dimethylamino-trans-azobenzene structure has some delocalization effects on the geometry or conformation of MR derivatives whether neutral, mono-, di- or de-protonated.

• Mass Spectrometry Letters
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• 제12권2호
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• pp.41-46
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• 2021

Collision-induced dissociation (CID) and higher-energy collisional dissociation (HCD) are the widely used fragmentation technique in mass spectrometry-based proteomics studies. Understanding the fragmentation pattern from the tandem mass spectra using statistical methods helps to implement efficient spectrum analysis algorithms. The study characterizes the frequency of occurrence of multi-charged fragment ions and their neutral loss events of doubly and triply charged peptides in the CID and HCD spectrum. The dependency of the length of the fragment ion on the occurrence of multi-charged fragment ion is characterized here. Study shows that the singly charged fragment ions are generally dominated in the doubly charged peptide spectrum. However, as the length of the product ion increases, the frequency of occurrence of charge 2 fragment ions increases. The y- ions have more tendencies to generate charge 2 fragment ions than b- ions, both in CID and HCD spectrum. The frequency of occurrence of charge 2 fragment ion peaks is prominent upon the dissociation of the triply charged peptides. For triply charged peptides, product ion of higher length occurred in multiple charge states in CID spectrum. The neutral loss peaks mostly exist in charge 2 states in the triply charged peptide spectrum. The b-ions peaks are observed in much less frequency than y-ions in HCD spectrum as the length of the fragment increases. Isotopic peaks are occurred in charge 2 state both in doubly and triply charged peptide's HCD spectrum.

• 한국산학기술학회논문지
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• 제19권4호
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• pp.433-438
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• 2018

본 연구는 기존의 1기간 모형과는 달리 노력을 투입하는 시점과 손실 발생 시점간의 차이를 고려한 2기간 모형을 가정하고 있다. 또한 모호성 회피성향이 손실 발생 확률 및 손실의 크기를 줄이기 위한 노력에 미치는 영향을 살펴보고 있다. 이때 손실의 발생 자체는 이항 분포를 따르나, 모호성 회피성향을 가정하기 위해 그 분포가 상태 변수에 의존하는 함수의 형태를 갖는다고 가정한다. 그 결과 첫째, 모호성 회피적인 개인이 모호성 중립적인 개인에 비해 언제나 더 많은 노력을 기울이는 것은 아니다. 둘째, 1기간에서는 나타나지 않았던 절대모호성회피성향이 노력 수준에 미치는 영향을 살펴볼 수 있었다. 2기간 모형에서 증가하지 않는 절대모호성회피성향은 모호성 회피적인 개인이 모호성 중립적인 개인에 비해 더 많은 노력을 기울이기 위한 필요조건이다. 또한 상태에 대한 확률 함수의 형태에 따라 노력의 증가하거나 감소할 수 있다. 마지막으로 이러한 결과는 개인이 위험중립적이거나 위험선호적이더라도 성립한다. 따라서 본 연구는 모호성 회피성향은 위험 회피성향과는 독립적으로 고려될 필요가 있다는 것을 밝히고 있다.

• Journal of Power Electronics
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• 제15권5호
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• pp.1380-1391
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• 2015

This paper provides a loss analysis and comparison of high power semiconductor devices in 5MW Permanent Magnet Synchronous Generator (PMSG) Medium Voltage (MV) Wind Turbine Systems (WTSs). High power semiconductor devices of the press-pack type IGCT, module type IGBT, press-pack type IGBT, and press-pack type IEGT of both 4.5kV and 6.5kV are considered in this paper. Benchmarking is performed based on the back-to-back type 3-level Neutral Point Clamped Voltage Source Converters (3L-NPC VSCs) supplied from a grid voltage of 4160V. The feasible number of semiconductor devices in parallel is designed through a loss analysis considering both the conduction and switching losses under the operating conditions of 5MW PMSG wind turbines, particularly for application in offshore wind farms. This paper investigates the loss analysis and thermal performance of 5MW 3L-NPC wind power inverters under the operating conditions of various power factors. The loss analysis and thermal analysis are confirmed through PLECS Blockset simulations with Matlab Simulink. The comparison results show that the press-pack type IGCT has the highest efficiency including the snubber loss factor.

• 한국CDE학회논문집
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• 제13권3호
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• pp.175-186
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• 2008

For the success to PLM in manufacturing industries, the creation, management and coordination of all product-related information are essential, and the exchange of product information and data has become an important part of the product development. In this paper, we define the neutral schema, and it refers to PLM Services. Based on this neutral schema, we develop the PLM Integrator to exchange product information and data between diverse heterogeneous systems including PDM systems. We apply the PLM Integrator developed in this paper to commercial PDM systems such as SmarTeam, Teamcenter Engineering and MEMPHIS which is a data exchange middleware system for VR applications. By implementations, exchanges of product information and data can be done without loss of information. Also, the PLM Integrator can upload and download product information, data and related files. The result of this paper can not only reduce unnecessary efforts for data exchanging between different information systems including PDM/PLM systems but also provide a collaborative environment for PLM.

• BMB Reports
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• 제28권2호
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• pp.138-142
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• 1995

An anticoagulant/fibrinolytic protease was purified to homogeneity from the earthworm Lumbricus rubellus. The protein was a single chain glycoprotein of 32 kDa that exhibited strong proteolytic activity on human thrombin and fibrin clots. Proteolytic degradation of these plasma proteins by the purified enzyme occurred at a neutral pH range. Among several human plasma proteins tested as possible substrates for the protease reaction, the 32 kDa enzyme specifically hydrolyzed both thrombin and fibrin polymers without affecting other proteins, such as serum albumin, immunoglobulin, and hemoglobin. Treatment of the purified enzyme at neutral pH with either phenylmethylsulfonylfluoride or soybean trypsin inhibitor resulted in a loss of catalytic activity. The enzyme hydrolyzed the chromogenic substrate H-D-Phe-L-Pipecolyl-L-Arg-p-nitroanilide with a $K_m$ value of 1.1 ${\mu}M$ at a neutral pH. These results suggest that the anticoagulant/fibrinolytic enzyme from Lumbricus rubellus is a member of the serine protease family having a trypsin-like active site, and one of the potential clevage sites for the enzyme is the carbonyl side of arginine residues in polypeptide chains.

• 조명전기설비학회논문지
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• 제27권6호
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• pp.50-58
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• 2013

The Neutral Beam Injection(NBI) generates ultra-high temperature energy in the tokamak of nuclear fusion. The NBI consists of filament power supply acceleration and deceleration power supply and arc power supply(APS). The APS has characteristics of low voltage and high current. APS generate arc through constant output of voltage and current. So this paper proposed suitable buck converter for low voltage and high current. The case of proposed buck converter used parallel switch because it can increase capacity and decrease conduction loss. When an arc is generated, the NBI chamber occur high voltage. And it will break output capacitor of buck converter. Therefore the output capacitor was removed in the proposed converter. Thus buck converter with constant output is the most important design of the output inductor. In this paper, designed APS verified operation of system and stability through simulation and prototype.