• Proceedings of the Korean Information Science Society Conference
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• 2006.10b
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• pp.218-222
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• 2006

우수한 능력의 인공지능 개체로 구성된 게임은 그렇지 못한 게임에 비해 더 나은 흥미를 사용자에게 제공할 수 있다. 미국 Valve사의 Half-Life, Counter-Strike 및 한국 Dragonfly사의 Special-Force와 같은 실시간 FPS 전투게임에서 상대편에 대한 검색 및 목표 화하는(Targeting) 기법은 인공개체의 전투력에 중요한 하나의 요소이다. 하지만 이 같은 경우의Targeting은 정적인 대상에 대한 것이 아니라 동적인 대상에 대한 것이므로 단순한 산술 계산으로는 실용적인 효과를 내기 힘들다. 본 논문에서는 Neural Network를 이용한 학습기법을 사용하여 동적인 개체에 대한 효과적인 Targeting기법을 제안한다. 제안한 기법은 매 순간 변화하는 상황정보와 Virtual bullet이라는 가상 미사일 개념을 활용하여 학습 Data를 모델링한 후 Neural Network로 학습시켜 효과적인 Targeting이 가능하도록 구현하였다. 제안한 기법은 Java기반의 탱크전투 시뮬레이션 Framework인 Robocode에 적용하여 그 성능을 평가하였다. 제안된 기법으로 제작된 Robot(Crystal 1.0)은 ‘2006 Robocode Korea Cup에서 우승을 차지하였다.

• Proceedings of the Korean Operations and Management Science Society Conference
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• 2005.10a
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• pp.189-206
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• 2005

Much of work on network externality assumed network effects are dependent on the network size. Therefore, very little consideration is given to the view that marginal benefits from joining the network may not increase with the network size if consumer benefits come from the direct interaction with neighbors, namely local network. In this study, we used the agent-based simulation method to reexamine the effectiveness of the traditional network market strategy under the presence of the local network where two incompatible technologies compete. We found that the strategy of growing an initial customer base is not effective under the presence of the local network. Our study also showed that targeting customers based on their technology Preference is not as effective as targeting customers within the same local network. As a result, the focus of a network market strategy should be directed to taking advantage of the customer network.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.8
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• pp.3905-3909
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• 2012

Ovarian cancer is the fifth leading cause of cancer death in women aged 35 to 74 years. Although there are several popular hypothesis of ovarian cancer pathogenesis, the genetic mechanisms are far from being clear. Recently, systems biology approaches such as network-based methods have been successfully applied to elucidate the mechanisms of diseases. In this study, we constructed a crosstalk network among ovarian cancer related pathways by integrating protein-protein interactions and KEGG pathway information. Several significant pathways were identified to crosstalk with each other in ovarian cancer, such as the chemokine, Notch, Wnt and NOD-like receptor signaling pathways. Results from these studies will provide the groundwork for a combination therapy approach targeting multiple pathways which will likely be more effective than targeting one pathway alone.

• Molecules and Cells
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• v.46 no.1
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• pp.21-32
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• 2023

MicroRNAs (miRNAs) play cardinal roles in regulating biological pathways and processes, resulting in significant physiological effects. To understand the complex regulatory network of miRNAs, previous studies have utilized massivescale datasets of miRNA targeting and attempted to computationally predict the functional targets of miRNAs. Many miRNA target prediction tools have been developed and are widely used by scientists from various fields of biology and medicine. Most of these tools consider seed pairing between miRNAs and their mRNA targets and additionally consider other determinants to improve prediction accuracy. However, these tools exhibit limited prediction accuracy and high false positive rates. The utilization of additional determinants, such as RNA modifications and RNA-binding protein binding sites, may further improve miRNA target prediction. In this review, we discuss the determinants of functional miRNA targeting that are currently used in miRNA target prediction and the potentially predictive but unappreciated determinants that may improve prediction accuracy.

• Journal of Intelligence and Information Systems
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• v.16 no.2
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• pp.109-128
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• 2010

The purpose of our research is to figure out the 'non-financial value' of consumers applying networks amongst consumer groups, the data-based marketing strategy to the analysis and delve into the ways for enhancing effectives in marketing activities by adapting the value to the marketing. To verify the authenticity of the points, we did the empirical test on the consumer group using 'the Essence Cosmetics Products' of high involvement that is deeply affected by consumer perceptions and the word-of-mouth activities. 1) The empirical analysis reveals the following features. First, the segmented market for 'Essence Consumer' is composed of several independent networks, each network shows to have the consumers that is high degree centrality and closeness centrality. Second, the result proves the authenticity of the non-financial value for boosting corporate profits by the high degree centrality and closeness centrality consumer's word-of-mouth activities. Lastly, we verify that there lies a difference in the network structure of 'Essence Cosmetics Market'per each product origin(domestic, foreign) and demographic characteristics. It does, therefore, indicate the need to consider the features applying mutually complementary for the network targeting.

• Journal of the Korea Institute of Military Science and Technology
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• v.24 no.2
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• pp.187-196
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• 2021

The Network-Centric warfare over weapon data link networks has been developed for the recent decade. Since the US navy had begun to develop tactical digital information chain, it has gradually transformed into weapon data link technology. As data link network system and its protocol have been advanced into high-technology, focusing and targeting on moving targets become possible in net-enabled environments. However, it is difficult to identify the primary information from numerous battlefields and understanding approaches to damage a target in a timely manner. In this paper, to better understand the targeting assessment, we suggest a specific solution: Bomb Hit Indication(BHI) using information in weapon data link messages. In order to prove our suggestion, we implement the BHI solution and apply it into the weapon data link integrating system.

• Journal of Life Science
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• v.28 no.2
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• pp.162-169
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• 2018

Many cytoplasmic proteins are targeted to the cytoplasmic membrane of the trans-Golgi network (TGN) via an N-terminal short helix. We previously showed that the 20 N-terminal amino acids of Aplysia phosphodiesterase 4 (ApPDE4) long form are sufficient for its targeting to the plasma membrane and the TGN. The N-terminus of the ApPDE4 long form binds to PI4P and sulfatide in vitro. Therefore, in order to decipher the roles of sulfatide in Golgi complex targeting, we examined the cellular localization of sulfatide-binding peptides. In this study, we found that enhanced green fluorescent protein (EGFP) fused to the C-terminus of modified sulfatide- and heparin-binding peptides (mHSBP-EGFP) was localized to the TGN. On the other hand, its mutant, in which tryptophan was replaced with an alanine, leading to the impairment of heparin and sulfatide binding, was localized to cytosol. We also found that the TGN targeting of mHSBP-EGFP is impaired by the treatment of antimycin A, phenylarsine oxide (PAO), and adenosine but not a high concentration of wortmannin. These results suggest that PAO and adenosine-sensitive kinases, including phosphatidylinositol 4-kinase II, may play key roles in the recruitment of mHSBP-EGFP.

• Journal of the Korea Institute of Information Security & Cryptology
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• v.28 no.4
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• pp.1009-1019
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• 2018

Bitcoin is the first application utilizing the blockchain, but it has limitations in terms of scalability. The concept of Lightning Network was recently introduced to address the scalability problem of Bitcoin. In this paper, we found that the real-world Bitcoin Lightning Network shows the scale-free property. Therefore, the Bitcoin Lightning Network can be vulnerable to the intentional attacks targeting some specific nodes in the network while it is still robust to the random node failures. We experimentally analyze the robustness of the Bitcoin's Lightning Network via the simulation of network attack model. Our simulation results demonstrate that the real-world Lightning Network is vulnerable to target attacks that destroy a few nodes with high degree.

• International Journal of Highway Engineering
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• v.20 no.1
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• pp.35-45
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• 2018

PURPOSES : This study examines the performance changes of road networks according to the strength of a disaster, and proposes a method for estimating the quantitative resilience according to the road-network performance changes and damage scale. This study also selected high-influence road sections, according to disasters targeting the road network, and aimed to analyze their hazard resilience from the network aspect through a scenario analysis of the damage recovery after a disaster occurred. METHODS : The analysis was conducted targeting Sejong City in South Korea. The disaster situation was set up using the TransCAD and VISSIM traffic-simulation software. First, the study analyzed how road-network damage changed the user's travel pattern and travel time, and how it affected the complete network. Secondly, the functional aspects of the road networks were analyzed using quantitative resilience. Finally, based on the road-network performance change and resilience, priority-management road sections were selected. RESULTS : According to the analysis results, when a road section has relatively low connectivity and low traffic, its effect on the complete network is insignificant. Moreover, certain road sections with relatively high importance can suffer a performance loss from major damage, for e.g., sections where bridges, tunnels, or underground roads are located, roads where no bypasses exist or they exist far from the concerned road, including entrances and exits to suburban areas. Relatively important roads have the potential to significantly degrade the network performance when a disaster occurs. Because of the high risk of delays or isolation, they may lead to secondary damage. Thus, it is necessary to manage the roads to maintain their performance. CONCLUSIONS : As a baseline study to establish measures for traffic prevention, this study considered the performance of a road network, selected high-influence road sections within the road network, and analyzed the quantitative resilience of the road network according to scenarios. The road users' passage-pattern changes were analyzed through simulation analysis using the User Equilibrium model. Based on the analysis results, the resilience in each scenario was examined and compared. Sections where a road's performance loss had a significant influence on the network were targeted. The study results were judged to become basic research data for establishing response plans to restore the original functions and performance of the destroyed and damage road networks, and for selecting maintenance priorities.

• Journal of Satellite, Information and Communications
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• v.9 no.1
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• pp.45-50
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• 2014

In this paper, broadband wireless smart city network coverage was implemented targeting a city (Wonju) using the wireless mesh network. Through this, we could provide wireless network that can easily add network and be repaired easily and have high economic effect. In order to implement broadband wireless smart city network coverage, wireless mesh network has been designed through pre-survey of the region and appropriate selecting of equipment. In addition, the designed network is examined, evaluated and compared with existing network though simulation. The aim of this paper is to prove high cost saving effect of wireless mesh network and its superior performance and to suggest future oriented integrated network of Green IT though research.