• Title/Summary/Keyword: Network Discovery

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Study on Effects of Startup Characteristics on Entrepreneurship Performance: Focusing on the Intermediary Effects of the Accelerator Role (스타트업의 특성이 창업성과에 미치는 영향에 관한 연구: 액셀러레이터 역할의 매개효과 중심으로)

  • Yongtae Kim;Chulmoo Heo
    • Asia-Pacific Journal of Business Venturing and Entrepreneurship
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    • v.18 no.2
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    • pp.141-156
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    • 2023
  • The advancement of Information and Communication Technology (ICT), along with the expansion of government and private investment in startup discovery and funding, has led to the emergence of startups seeking to generate outstanding results based on innovative ideas. As successful startups serve as role models, the number of aspiring entrepreneurs preparing to launch their own startups continues to increase. However, unlike entrepreneurs who challenge themselves with serial entrepreneurship after experiencing success, early-stage startups face various challenges such as team building, technology development, and fundraising. Accelerators play a dual role of mentor and investor by providing education, mentoring, consulting, network connection, and initial investment activities to help startups overcome various challenges they face and facilitate their growth. This study investigated whether there is a correlation between the characteristics of startups and their entrepreneurial performance, and analyzed whether accelerators mediate the relationship between startup characteristics and entrepreneurial performance. A total of 11 hypotheses were proposed, and a survey was conducted on 302 startup founders and employees located across the country, including the metropolitan area, for empirical research. SPSS 23.0 and Amos 23.0 were used for statistical analysis. Through this study, it was found that factors such as innovation, organizational culture, financial characteristics, and learning orientation among the characteristics of startups, rather than having a direct impact on entrepreneurial performance, are linked to entrepreneurial performance through the role of accelerators. By analyzing the impact factors of startup characteristics on entrepreneurial performance, this study presents research on the role of accelerators and provides institutional improvements. It is expected to contribute to the expansion of investment and differentiated acceleration programs, enabling startups to seize the market and grow stably in the market.

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Insights into the Role of Follicular Helper T Cells in Autoimmunity

  • Park, Hong-Jai;Kim, Do-Hyun;Lim, Sang-Ho;Kim, Won-Ju;Youn, Jeehee;Choi, Youn-Soo;Choi, Je-Min
    • IMMUNE NETWORK
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    • v.14 no.1
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    • pp.21-29
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    • 2014
  • Follicular helper T ($T_{FH}$) cells are recently highlighted as their crucial role for humoral immunity to infection as well as their abnormal control to induce autoimmune disease. During an infection, na$\ddot{i}$ve T cells are differentiating into $T_{FH}$ cells which mediate memory B cells and long-lived plasma cells in germinal center (GC). $T_{FH}$ cells are characterized by their expression of master regulator, Bcl-6, and chemokine receptor, CXCR5, which are essential for the migration of T cells into the B cell follicle. Within the follicle, crosstalk occurs between B cells and $T_{FH}$ cells, leading to class switch recombination and affinity maturation. Various signaling molecules, including cytokines, surface molecules, and transcription factors are involved in $T_{FH}$ cell differentiation. IL-6 and IL-21 cytokine-mediated STAT signaling pathways, including STAT1 and STAT3, are crucial for inducing Bcl-6 expression and $T_{FH}$ cell differentiation. $T_{FH}$ cells express important surface molecules such as ICOS, PD-1, IL-21, BTLA, SAP and CD40L for mediating the interaction between T and B cells. Recently, two types of microRNA (miRNA) were found to be involved in the regulation of $T_{FH}$ cells. The miR-17-92 cluster induces Bcl-6 and $T_{FH}$ cell differentiation, whereas miR-10a negatively regulates Bcl-6 expression in T cells. In addition, follicular regulatory T ($T_{FR}$) cells are studied as thymus-derived $CXCR5^+PD-1^+Foxp3^+\;T_{reg}$ cells that play a significant role in limiting the GC response. Regulation of $T_{FH}$ cell differentiation and the GC reaction via miRNA and $T_{FR}$ cells could be important regulatory mechanisms for maintaining immune tolerance and preventing autoimmune diseases such as systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA). Here, we review recent studies on the various factors that affect $T_{FH}$ cell differentiation, and the role of $T_{FH}$ cells in autoimmune diseases.

User Centered Design and Development Strategies for Participatory Learning Media (사용자중심의 참여 미디어 교육시스템 프로토타입 개발 전략)

  • Ahn, Mi-Lee;Cho, Y.C.;Hwang, Y.J.;Cha, H.J.;Kim, H.J.
    • 한국HCI학회:학술대회논문집
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    • 2009.02a
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    • pp.926-932
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    • 2009
  • Recently many research reports on effective use of mobile devices for museums to provide information on displayed artifacts providing individualized learning space, collaborative learning, and discovery learning, Such devices have many possibilities to support learning as a participatory media and social network. Mobile devices are used, however, limited for its usability and lack in providing expected learning experiences. It offers one-way interaction and they are often limited in providing customized services for different patrons to experience learning and entertainment. In this research, we have adopted user centered design approach to identify the needs and possible usage of PDA system in the museum. Research methods include contextual observation and inquiry with symbolic interactionism for qualitative research and its epistemology. We have developed conceptual model with scenario and storyboard method, and developed vertical prototype with Flash.

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Implementation of Control Point, Digital TV, and Light Controller Emulator on Embedded System Using UPnP Home Networking Control Middleware (홈 네트워킹 제어 미들웨어인 UPnP를 이용한 Control Point 및 내장형 시스템 상에서의 DTV와 전등 제어기 에뮬레이터 구현)

  • Jeon Ho-In
    • Journal of The Institute of Information and Telecommunication Facilities Engineering
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    • v.1 no.1
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    • pp.6-25
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    • 2002
  • In this paper, we have implemented UPnP Devices which emulate a Control Point, a Light Controller, and a Digital TV. The Control Point has been developed on Linux host system by using C language. The UPnP Devices emulating the Digital TV and Light Controller are running on embedded linux developer board. For the development of UPnP Devices, UPnP SDK API Vl.04 made by Intel Co. Ltd. has been ported on Assabet Linux Reference board to implement the UPnP protocol. After we analyze and design some services of Digital TV device, we have applied UPnP Device program to those devices. UPnP SDK vl .04 consists of APIs which support HTTP, SSDP, SOAP, GENA and XML DOM Level-1 that are cores of UPnP protocol. The C program written for the UPnP Control Point has been compiled and executed on Linux-based PC. The embedded system running on Embedded Linux OS has been connected all together through Ethernet which allows IP-based communications. Under this environment, the UPnP programs are being executed on each device. Control Point, when in operational mode, discovers UPnP Devices on the network and displays the device list on the consol. By selecting one of the functionalities of the device services that are displayed on the Control Point, the controllability has been accomplished. The experiment that we performed in this thesis have revealed that the Control Point and UPnP Devices have supported the protocols including SSDP, SOAP, GENA, and DHCP.

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Design of Serendipity Service Based on Near Field Communication Technology (NFC 기반 세렌디피티 시스템 설계)

  • Lee, Kyoung-Jun;Hong, Sung-Woo
    • Journal of Intelligence and Information Systems
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    • v.17 no.4
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    • pp.293-304
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    • 2011
  • The world of ubiquitous computing is one in which we will be surrounded by an ever-richer set of networked devices and services. Especially, mobile phone now becomes one of the key issues in ubiquitous computing environments. Mobile phones have been infecting our normal lives more thoroughly, and are the fastest technology in human history that has been adapted to people. In Korea, the number of mobile phones registered to the telecom company, is more than the population of the country. Last year, the numbers of mobile phone sold are many times more than the number of personal computer sold. The new advanced technology of mobile phone is now becoming the most concern on every field of technologies. The mix of wireless communication technology (wifi) and mobile phone (smart phone) has made a new world of ubiquitous computing and people can always access to the network anywhere, in high speed, and easily. In such a world, people cannot expect to have available to us specific applications that allow them to accomplish every conceivable combination of information that they might wish. They are willing to have information they want at easy way, and fast way, compared to the world we had before, where we had to have a desktop, cable connection, limited application, and limited speed to achieve what they want. Instead, now people can believe that many of their interactions will be through highly generic tools that allow end-user discovery, configuration, interconnection, and control of the devices around them. Serendipity is an application of the architecture that will help people to solve a concern of achieving their information. The word 'serendipity', introduced to scientific fields in eighteenth century, is the meaning of making new discoveries by accidents and sagacity. By combining to the field of ubiquitous computing and smart phone, it will change the way of achieving the information. Serendipity may enable professional practitioners to function more effectively in the unpredictable, dynamic environment that informs the reality of information seeking. This paper designs the Serendipity Service based on NFC (Near Field Communication) technology. When users of NFC smart phone get information and services by touching the NFC tags, serendipity service will be core services which will give an unexpected but valuable finding. This paper proposes the architecture, scenario and the interface of serendipity service using tag touch data, serendipity cases, serendipity rule base and user profile.

A BPM Activity-Performer Correspondence Analysis Method (BPM 기반의 업무-수행자 대응분석 기법)

  • Ahn, Hyun;Park, Chungun;Kim, Kwanghoon
    • Journal of Internet Computing and Services
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    • v.14 no.4
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    • pp.63-72
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    • 2013
  • Business Process Intelligence (BPI) is one of the emerging technologies in the knowledge discovery and analysis area. BPI deals with a series of techniques from discovering knowledge to analyzing the discovered knowledge in BPM-supported organizations. By means of the BPI technology, we are able to provide the full functionality of control, monitoring, prediction, and optimization of process-supported organizational knowledge. Particularly, we focus on the focal organizational knowledge, which is so-called the BPM activity-performer affiliation networking knowledge that represents the affiliated relationships between performers and activities in enacting a specific business process model. That is, in this paper we devise a statistical analysis method to be applied to the BPM activity-performer affiliation networking knowledge, and dubbed it the activity-performer correspondence analysis method. The devised method consists of a series of pipelined phases from the generation of a bipartite matrix to the visualization of the analysis result, and through the method we are eventually able to analyze the degree of correspondences between a group of performers and a group of activities involved in a business process model or a package of business process models. Conclusively, we strongly expect the effectiveness and efficiency of the human resources allotments, and the improvement of the correlational degree between business activities and performers, in planning and designing business process models and packages for the BPM-supported organization, through the activity-performer correspondence analysis method.

A Study on Industry-University Cooperation Based the Link Strategy of Localization Project: Focusing on Chungcheong-Provincial Research Town Characterization Linkage Strategy (지역특화 전략에 기반한 산학협력에 관한 연구: 충청권 연구마을 특성화 연계 전략을 중심으로)

  • Hong, Eun-Young;Choi, Jong-In
    • Asia-Pacific Journal of Business Venturing and Entrepreneurship
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    • v.12 no.2
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    • pp.105-115
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    • 2017
  • Innovative cluster theory promotes cluster growth as the tacit knowledge and know-how approach becomes easier through industry-academia cooperation. Industry-academia cooperation is an innovation network policy that supports joint research between industry and academia. In this respect, The Flow of recent government policy is activating I-U support office in university & research institute for enable I-U Cooperation ecosystem. Then SMB Administration was first performed "research village support program", to support SMEs in industry-university cooperative research capabilities by integrating the research, development and commercializatin of the university or research institution with excellent research base in 2013. However, I-U Cooperation R&D must be based the link strategy of Localization in order to be better composition at research village. In the case of research villages where specialized discovery strategies are well reflected, integration of similar companies in specialized fields will naturally create clusters and create synergy of research. This study searching and summarizing through a recent Hanbat National University research village. Finally, we propose the implications of government policy.

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Rheological Behavior of Lyotropilc Solutions of Cellulose in the $NH_3/NH_4SCN$ Solvent System

  • Jo, Jae-Jeong;Cuculo, J.A.;Theil, M.H.
    • Proceedings of the Korean Fiber Society Conference
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    • 1990.06b
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    • pp.36-37
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    • 1990
  • In the past, facile dissolution of cellulose has been hampered by the lack of suitable nondegrading solvents. Recently, this problem has been solved in our laboratory by the discovery of an inexpensive, convenient solvent system, that is the mixture of $NH_3\;and\;NH_4SCN$, for cellulose. Also, the $cellulose/NH_3/NH_4SCN$ solution system has been found to form the anisotropic, i.e., liquid crystalline phase. It is believed that both the cholesterio and the nematic phase occur. This finding has prompted extensive on-going researoh on the formation of the liquid crystalline phase from an inexpensive natural source such as cellulose since the nematic phase is envisioned as an excellent precursor sources for products with desirable properties, for example, high modulus and high strength. This interest naturally leads to a desire to understand the theological properties of the nematic phase so that the transformation of the nematic phase to the solid state with desirable properties can be efficiently accomplished, ;From this point of view, the theological behavior of the $cellulose/NH3_/NH_4SCN$ system has been studied as a function of shear rate and shear stress over a wide range of solvent compositions, cellulose concentration, centrifugation and urea contents, Results indicate that the viscosity decreases with increasing shear rate. A marked shear thinning behavior and a quasi-Newtonian behavior were observed in the low shear rate region and in the high shear rate region, respectively for all solvent compositions. The $cellulose/NH_3/NH_4SCN$ solution system only exhibited the viscosity increase with increasing cellulose concentration and failed to show the viscosity drop generally observed at the point of incipience of liquid crystal formation, This may be due to the gel-like nature of the solution by the association of the rodlike molecules into bundles which may serve as crosslinking points giving the cellulose solution a network structure. Also, simply hydrogen bonding may be so restrictive of molecular mobility that a viscosity drop is blocked. In addition to the above results, yield stress and thixotropy were also observed in the $cellulose/NH_3/NB_4SCN$ solution system which are characteristics of liquid crystal and gel, The results of the effect of centrifugation on viscosity show that viscosity decreases by the application of centrifugation. This may be explained by the change of the piled polydomain structure to the dispersed polydomain structure due to the pressure gradient generated during centrifugation.ation.

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Genome-Wide Association Study of Bone Mineral Density in Korean Men

  • Bae, Ye Seul;Im, Sun-Wha;Kang, Mi So;Kim, Jin Hee;Lee, Soon Hang;Cho, Be Long;Park, Jin Ho;Nam, You-Seon;Son, Ho-Young;Yang, San Deok;Sung, Joohon;Oh, Kwang Ho;Yun, Jae Moon;Kim, Jong Il
    • Genomics & Informatics
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    • v.14 no.2
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    • pp.62-68
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    • 2016
  • Osteoporosis is a medical condition of global concern, with increasing incidence in both sexes. Bone mineral density (BMD), a highly heritable trait, has been proven a useful diagnostic factor in predicting fracture. Because medical information is lacking about male osteoporotic genetics, we conducted a genome-wide association study of BMD in Korean men. With 1,176 participants, we analyzed 4,414,664 single nucleotide polymorphisms (SNPs) after genomic imputation, and identified five SNPs and three loci correlated with bone density and strength. Multivariate linear regression models were applied to adjust for age and body mass index interference. Rs17124500 ($p=6.42{\times}10^{-7}$), rs34594869 ($p=6.53{\times}10^{-7}$) and rs17124504 ($p=6.53{\times}10^{-7}$) in 14q31.3 and rs140155614 ($p=8.64{\times}10^{-7}$) in 15q25.1 were significantly associated with lumbar spine BMD (LS-BMD), while rs111822233 ($p=6.35{\times}10^{-7}$) was linked with the femur total BMD (FT-BMD). Additionally, we analyzed the relationship between BMD and five genes previously identified in Korean men. Rs61382873 (p = 0.0009) in LRP5, rs9567003 (p = 0.0033) in TNFSF11 and rs9935828 (p = 0.0248) in FOXL1 were observed for LS-BMD. Furthermore, rs33997547 (p = 0.0057) in ZBTB and rs1664496 (p = 0.0012) in MEF2C were found to influence FT-BMD and rs61769193 (p = 0.0114) in ZBTB to influence femur neck BMD. We identified five SNPs and three genomic regions, associated with BMD. The significance of our results lies in the discovery of new loci, while also affirming a previously significant locus, as potential osteoporotic factors in the Korean male population.

Study on Context-Aware SOA based on Open Service Gateway initiative platform (OSGi플렛폼 기반의 상황인식 서비스지향아키텍쳐에 관한 연구)

  • Choi, Sung-Wook;Oh, Am-Suk;Kwon, Oh-Hyun;Kang, Si-Hyeob;Hong, Soon-Goo;Choi, Hyun-Rim
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.10 no.11
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    • pp.2083-2090
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    • 2006
  • In an proposed Context-Aware SOA(Service Oriented Architecture) based OSGi(Open Service Gateway initiative) platform, Service provider manages relative kinds of services in an integrative basis from various sensors, puts each service in a SOAP (Simple Object access Protocol) message, and register thorn to the UDDI(Universal Description Discovery and Integration) server of service registry, service requester retrivel the specified kinds of services and call them to service provider. Recently most context-aware technologies for ubiquitous home network are mainly putting emphasis on RFID/USN and location-based technology. Because of this, service-oriented architecture researches have not been made enough. Under the environment of an OSGi service platform, various context-aware services are dynamically mapping from various sensors, new services are being offered for the asking of users, and existing services are changing. Accordingly, the data sharing between services provided, management of service life cycle, and the facilitation of service distribution are needed. Taking into considering all these factors, this study has suggested an Context-Aware SOA based eclipse SOA Tools Platform using OSGi platform that can transaction throughtput of more than 546 TPS of distributional Little's Law from ATAM(Architecture Tradeoff Analysis Method) while remaining stable other condition.