• 제목/요약/키워드: Neoplasm outcome

검색결과 80건 처리시간 0.038초

Outcome of Management of Local Recurrence after Immediate Transverse Rectus Abdominis Myocutaneous Flap Breast Reconstruction

  • Lee, Taik Jong;Hur, Wu Jin;Kim, Eun Key;Ahn, Sei Hyun
    • Archives of Plastic Surgery
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    • 제39권4호
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    • pp.376-383
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    • 2012
  • Background No consensus has been reached regarding the outcome of management of local recurrence after transverse rectus abdominis myocutaneous (TRAM) flap breast reconstruction. This study demonstrated the presentation, management, and outcomes of local recurrence after immediate TRAM breast reconstruction. Methods A comparison was conducted among 1,000 consecutive patients who underwent immediate breast reconstruction with a pedicled TRAM flap (TRAM group) and 3,183 consecutive patients who underwent only modified radical mastectomy without reconstruction (MRM group) from January 2001 to December 2009. The presentation, treatment, and outcome including aesthetics and overall survival rate were analyzed. Results Local recurrences occurred in 18 (1.8%) patients (TRAM-LR group) who underwent TRAM breast reconstruction and 38 (1.2%) patients (MRM-LR group) who underwent MRM only (P=0.1712). Wide excision was indicated in almost all the local recurrence cases. Skin graft was required in 4 patients in the MRM-LR group, whereas only one patient required a skin graft to preserve the mound shape in the TRAM-LR group. The breast mound was maintained in all 17 patients that survived in the TRAM-LR group even after wide excision. The overall survival rate was 94.4% in the TRAM-LR group and 65.8% in the MRM-LR group (P=0.276). Conclusions Local recurrence after immediate TRAM flap breast reconstruction could be detected without delay and managed effectively by multiple modalities without reducing overall survival rates. Breast mound reconstruction with soft autologous tissue allowed for primary closure in most of the cases. In all of the patients who survived, the contour of their reconstructed breast remained.

흉강경을 이용한 식도 평활근종의 절제 (Thoracoscopic Enucleation of Esophageal Leiomyoma)

  • 이성호
    • Journal of Chest Surgery
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    • 제28권5호
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    • pp.518-520
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    • 1995
  • Leiomyoma is the most common benign tumor of the esophagus,and surgical enucleation is the treatment of choice. Recently we successfully performed thoracoscopic enucleation of large esophageal leiomyoma without complication in one patient. The 46 years old male patient complained epigastric discomfort and showed a submucosal mass in lower esophagus under the endoscopic ultrasonography . During operation minimal perforation occurred, it was closed with clipping without conversion to an open procedure.The tumor size was 8cm x 3cm x 1.5cm respectively. There were less post-operative pain,minimal wound size, and early recovery time.Patient was satisfactory these outcome. These result suggest that esophageal enucleation was performed more large size benign tumor and esophageal perforation during operation was treated thoracoscopically.

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The International Association for the Study of Lung Cancer Lymph Node Map: A Radiologic Atlas and Review

  • Kim, Jin Hwan;van Beek JR, Edwin;Murchison, John T;Marin, Aleksander;Mirsadraee, Saeed
    • Tuberculosis and Respiratory Diseases
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    • 제78권3호
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    • pp.180-189
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    • 2015
  • Accurate lymph node staging of lung cancer is crucial in determining optimal treatment plans and predicting patient outcome. Currently used lymph node maps have been reconciled to the internationally accepted International Association for the Study of Lung Cancer (IASLC) map published in the seventh edition of TNM classification system of malignant tumours. This article provides computed tomographic illustrations of the IASLC nodal map, to facilitate its application in day-to-day clinical practice in order to increase the appropriate classification in lung cancer staging.

Surgical Management of Recurrent Leiomyosarcoma in Heart

  • Kim, Jong Duk;Kim, Jun Seok;Hwang, Tae Suk;Shin, Je Kyoun;Song, Meong Gun
    • Journal of Chest Surgery
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    • 제47권1호
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    • pp.35-38
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    • 2014
  • Leiomyosarcoma may occur anywhere in the body but rarely occurs in the heart or great vessels. Leiomyosarcoma may be managed by surgical resection with or without chemotherapy or radiotherapy. Owing to the high rate of metastasis and poor prognosis, a definitive treatment modality for leiomyosarcoma has not yet been suggested. This case study reports the surgical management of the recurrent leiomyosarcoma of the heart and the great vessels in a 63-year-old woman.

Giant Cell Tumor involving the Ulnar Diaphysis

  • Kim, Ji-Hyeung;Han, Il-Kyu;Kang, Hyun-Guy;Kim, Han-Soo
    • 대한골관절종양학회지
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    • 제13권2호
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    • pp.152-156
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    • 2007
  • Giant cell tumor of bone is relatively common neoplasm usually involving epiphysis of long bone. And rarely it involves the diaphysis or metaphysis without epiphyseal extension. We report on an 18-year-old girl with giant cell tumor of ulnar diaphysis. She was treated with wide excision and reconstuction with nonvascularized autogenous fibular graft. We harvested fibular fragment preserving fibular continuity to reduce donor site morbidity. Surgical outcome and functional result was excellent.

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섬모원주상피로 피복된 고환내 단순낭 1례 (Intratesticular Simple cyst lined by ciliated columnar epithelium: A Case Report)

  • 김지윤;임화수;문기학;김미진;조재호
    • Journal of Yeungnam Medical Science
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    • 제22권2호
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    • pp.266-269
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    • 2005
  • An intratesticular simple cyst is a rare lesion. The pathogenesis of such lesions is uncertain. Clinically, an intratesticular simple cyst may be difficult to differentiate from a cystic neoplasm. However, preoperative diagnosis is possible using ultrasonography (US). Testis-sparing surgery with simple enucleation of the cyst has a favorable outcome. We report an intratesticular simple cyst in a 48-year-old male who had a non-tender cystic mass in the right testis for 2 years. The diagnosis was made by preoperative US. The patient underwent a testis-sparing surgery. After simple excision of the cyst, histological examination revealed a simple cyst lined by ciliated cuboidal and columnar epithelium.

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Postoperative chemoradiotherapy in high risk locally advanced gastric cancer

  • Song, Sanghyuk;Chie, Eui Kyu;Kim, Kyubo;Lee, Hyuk-Joon;Yang, Han-Kwang;Han, Sae-Won;Oh, Do-Youn;Im, Seock-Ah;Bang, Yung-Jue;Ha, Sung W.
    • Radiation Oncology Journal
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    • 제30권4호
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    • pp.213-217
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    • 2012
  • Purpose: To evaluate treatment outcome of patients with high risk locally advanced gastric cancer after postoperative chemoradiotherapy. Materials and Methods: Between May 2003 and May 2012, thirteen patients who underwent postoperative chemoradiotherapy for gastric cancer with resection margin involvement or adjacent structure invasion were retrospectively analyzed. Concurrent chemotherapy was administered in 10 patients. Median dose of radiation was 50.4 Gy (range, 45 to 55.8 Gy). Results: The median follow-up duration for surviving patients was 48 months (range, 5 to 108 months). The 5-year overall survival rate was 42% and the 5-year disease-free survival rate was 28%. Major pattern of failure was peritoneal seeding with 46%. Locoregional recurrence was reported in only one patient. Grade 2 or higher gastrointestinal toxicity occurred in 54% of the patients. However, there was only one patient with higher than grade 3 toxicity. Conclusion: Despite reported suggested role of adjuvant radiotherapy with combination chemotherapy in gastric cancer, only very small portion of the patients underwent the treatment. Results from this study show that postoperative chemoradiotherapy provided excellent locoregional control with acceptable and manageable treatment related toxicity in patients with high risk locally advanced gastric cancer. Thus, postoperative chemoradiotherapy may improve treatment result in terms of locoregional control in these high risk patients. However, as these findings are based on small series, validation with larger cohort is suggested.

악성 고립성 섬유종 제거술 후 발생한 뇌척수액의 흉강내로의 유출 (CSF Leakage through a Subarachnoid-pleural Fistula after Resection of a Malignant Solitary Fibrous Tumor)

  • 최광호;이양행;황윤호;윤영철;조광현;정용태
    • Journal of Chest Surgery
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    • 제43권3호
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    • pp.332-335
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    • 2010
  • 악성 고립성 섬유종은 비교적 드문 종양으로 흉막, 횡격막, 후복막 및 심낭 등에서 발생할 수 있으며, 남녀 발생 빈도는 비슷하고 60~70세 사이에 호발하나 10대의 어린 나이에도 발생하는 경우가 있다. 17세 남자에서 악성 고립성 섬유종에 의해 인접한 좌측 9번째 늑골의 형태학적 변화가 있어 섬유종의 제거 및 늑골 근위부의 부분적 절제술을 시행하였다. 술 후 뇌척수액의 흉강 내로의 누출을 CT myelography로 확인 후 뇌척수액의 배액 및 부분적 반측 추궁 절제술 및 경질막 복원술을 통한 교정을 치험하여 발표하고자 한다.

일개 종합병원중심 가정간호 간호진단분류를 위한 NANDA와 HHCC의 적용 비교 (Application of NANDA and HHCC to Classification of Nursing Diagnosis in a Hospital-Based Home Health Care)

  • 이진경;박현애
    • 성인간호학회지
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    • 제12권4호
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    • pp.507-516
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    • 2000
  • This study examines that North American Nursing Diagnosis Association(NANDA) and Home Health Care Classification(HHCC) is appropriate to classify home health care client's nursing problems and suggests a modified nursing diagnosis classification system. Two hundred and forty-nine clients' records at a general hospital were reviewed and nursing problems were diagnosed according to each classification system. Results of this study are as follows. The major client's medical diagnosis are pregnancy, childbirth and puerperium, malignant neoplasm, and benign neoplasm. Of four hundred and sixty-three nursing problems, all nursing problems made a diagnos according to HHCC, while three hundred and eighty-five made a diagnosis according to NANDA. The HHCC diagnosis included 78 more nursing problems than NANDA. The discrepancy in the results may indicate a significant advantage to HHCC diagnosis because HHCC nomenclature was created empirically from hard data. However, this may be due to limitations in the data collection method so determination of which classification system is more useful is difficult to judge. However, nursing components of the HHCC are more concrete and clearer than human response patterns of the NANDA. Also the HHCC facilitates the documentation of patient care by computer, while using a conceptual framework consisting of 20 Care Components based on the nursing process: assessment, diagnosis, outcome identification, planning, implementation and evaluation. Accordingly, the practical application of HHCC is more useful than NANDA. Limitations of this study include a retrospective data collecting method and universality of samples. Further research for various samples that use prospective data collection method is recommended.

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위암 한약제제 임상시험 가이드라인 개발을 위한 한약제제 무작위배정 대조군 임상시험 고찰 (Analysis of Existing Guidelines and Randomized, Controlled, Clinical Trials for Development of [Guideline of Clinical Trial with Herbal Medicinal Product for gastric cancer])

  • 한가진;성신;김성수;김진성;박재우
    • 대한한의학회지
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    • 제38권3호
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    • pp.124-142
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    • 2017
  • Objectives: This study aimed to learn what should be considered in [Guideline of Clinical Trial with Herbal Medicinal Product for Gastric Cancer)] by analyzing the existing guidelines and clinical trials. Methods: The development committee searched guidelines for herbal medicinal product or gastric cancer developed already. Then, clinical trials for gastric cancer using herbal medicine were searched. The searched trials were analyzed in terms of inclusion and exclusion of participants, intervention, comparator, outcomes and trial design. Then, we compared the results of analysis with the regulations and guidelines of Ministry of Food and Drug Safety to suggest the issue that we will have to consider when making the [Guideline of Clinical Trial with Herbal Medicinal Product for Gastric Cancer]. Results: As a result, few guidelines for anti-tumor agent and clinical trial with herbal medicinal product were searched in the national institution homepage. In addition, 10 articles were searched by using the combination following search term; 'stomach neoplasm', 'herbal medicine', 'Medicine, Korean traditional', 'Medicine, Chinese Traditional', 'TCM', 'TKM', 'trial'. Most trials included gastric cancer participants with medical history of operation. The type of intervention was various such as decoction, granules, and fluid of intravenous injection. Comparators were diverse such as placebo, conventional treatment including chemotherapy and nutritional supplement. The most frequently used outcome for efficacy was quality of life. Besides, the symptom score, tumor response, and survival rate were used. Safety was investigated by recording adverse events. Conclusion: We found out some issue by reviewing the existing guidelines and comparing it with clinical trials for gastric cancer and herbal medicinal products. These results will be utilized for developing [Guideline of Clinical Trial with Herbal Medicinal Product for Gastric Cancer].