• Journal of Chest Surgery
• /
• 제12권1호
• /
• pp.23-29
• /
• 1979

Hyuk An, M.D.Atrial myxoma constitutes the most significant of all cardiac neoplasm. About 75% occur in the left atrium and 25% in the right. They may cause severe and progressive disease mimicking valvular heart disease. But recently attention to differential point in the clinical features along with various diagnostic techniques have allowed pre-operative diagnosis in the most cases. From April, `77 to Aug., `78, three cases of left atrial myxoma and one case of right atrial myxoma were operated in Seoul National University Hospital. Pre-operative diagnosis was established with echocardiography and cardiac angiography. In all cases, tumors were resected with cardiopulmonary bypass successfully, and discharged with good results.

• Journal of Chest Surgery
• /
• 제31권11호
• /
• pp.1094-1096
• /
• 1998

양심방 점액종은 세계적으로도 대단히 드문 질환의 하나로 우리 나라에서는 그간 2례 만이 발표되었다. 저자들은 점액종으로부터 떨어져 나간 색전으로 인한 것으로 여겨지는 뇌 경색증의 증상으로 혼미한 의식을 보였던 60세 남자 환자의 수술 증례를 보고하고자 한다. 저자들의 경우, 점액종은 난원공의 서로 다른 위치에서 생기어 각기 다른 심방 으로 자라 있었고, 심초음파 검사로 진단 직후 곧바로 응급수술을 시행하였다.

• Journal of Korean Neurosurgical Society
• /
• 제58권3호
• /
• pp.281-285
• /
• 2015

Myxomas are rare benign tumors that originate from mesenchymal tissue. They usually develop in the atrium of the heart, the skin, subcutaneous tissue, or bone. Involvement of the skull base with an intracranial extension is very rare and not well-described in the literature. We report a rare case of primary intracranial ossifying myxoma arising from the anterior skull base and mimicking a huge chondrosarcoma, and we review the relevant literature.

• Journal of Chest Surgery
• /
• 제29권1호
• /
• pp.99-102
• /
• 1996

Cardiac fibroma is a rare benign tumor of the heart that occurs primarily in infants and children. Prognosis depends on size, extent and site of tumor. Cardiac fibroma may invade the conduction system, papillary muscle and outflw of inflow tract of ventricle. In these situations, its clinical course is very poor Although operative mortality is high, surgical resection is treatment of choice because lethal arrhythmia and sudden death can be developed by the fibroma. A cardiac fibroma was successfully resected from the left ventricular myocardium of a 8 years old male patient in the Department of Thoracic and Cardiovascular Surgery, Chonbuk National University Hospital.

• 보험의학회지
• /
• 제2권1호
• /
• pp.116-121
• /
• 1985

We've reviewed 518 cases of claims by death that had occured for one year from April, 1983 to March, 1984. As a result, we came to following conclusions; First, the greater part of the death were due to Accidental death(19.1%), Heart disease(18.9%), Malignant neoplasm(17.4%), Liver cirrhosis(10.6%), and the Cerebrovascular disease(9.7%), which were occupied by 75.7% of the whole. Second, classifying them by medical examinations or non medical, death in case of non medical examination showed 89% of the whole. And for age, section ranging from 41 to 50, from 51 to 60 and from 31 to 40 took the overwhelming portion by 27.4%, 26.6%, and 17.4% respectively, those of which showed 71.4% of the whole. Third, for the period elapsed, death within 1 year from the entrance showed 31% and that from 1 year to under 2 years 20.5%. Thus the rate of early death under 2 years stood for 51.5% of the whole.

• 보험의학회지
• /
• 제4권1호
• /
• pp.86-92
• /
• 1987

We've reviewed 704 cases of claims by death that had occured for one year from April, 1985 to March, 1986. As a result, we came to following conclusions; First, the greater part of the death were due to Accidental death(25.0%), Malignant neoplasm(21.2%), Heart disease(12.9%), Liver cirrhosis(9.1%), and the cerebrovascular disease(5.5%), which were occupied by 73.7% of the whole. Second, classifying them by medical examinations or non medical, death in case of non medical examinations showed 94.3% of whole. And for age, section ranging from 40 to 49, from 50 to 59, and from 60 to 69 took the overwhelming portion by 28.6%, 24.2%, and 16.6% respectively, those of wich showed 69.4% of the whole. Third, for the period elapsed, death within 1 year from the entrance showed 16.9% and that from 1 year to under 2 years 18.8%, Thus the rate of early death under 2 years stood for 35.7% of the whole.

• Journal of Preventive Medicine and Public Health
• /
• 제14권1호
• /
• pp.39-42
• /
• 1981

Recent changes in the cause of death among the Korean population seem to be systematic and significant. Data on cause of death from the medically certified death certificates provide at least four types of evidence: a sudden increase in recent years in the numbers of death due to cerebrovascular disease or circulatory diseases including rheumatic fever and chronic heart diseases and atherosclerosis; increasing steadily in the numbers of death due to malignant neoplasm of various sites, and death due to accident; decreasing steadily in the numbers of death due to communicable diseases or parasite diseases; and a large number of deaths with unspecified symptoms and ill-defined conditions. The lack of complete registration of the deads occurred or the incomplete description on the cause of death reported suggests that statistical information of cause of death from the medically certified death records is meaningful in interpreting changing patterns.

• Journal of Chest Surgery
• /
• 제28권7호
• /
• pp.713-716
• /
• 1995

A 75-year-old man was admitted to the hospital because of a pericardial effusion.After 3 L of blood-stained pericardial fluid was drained, clinical examination together with echocardiography and chest computed tomography showed a tumor in the right atrium. At operation a pedunculated vascular tumor was found with a broad base which was embedded in the atrial wall and extended into the pericardium.A wide resection was performed resulting in a large defect of the right atrial wall. The defect was reconstructed with a pericardial patch. The patient did well postoperatively, but bloody pleural effusion developed later, presumably because of pulmonary metastasis. The patient died 2 months after surgery as a result of respiratory failure.

• Journal of Chest Surgery
• /
• 제34권12호
• /
• pp.960-963
• /
• 2001

거대 연골육종은 흉벽의 원발성 악성종양 중 임상에서 드물게 보는 형태이다. 60세 여자 환자가 전흉부에 발생한 거대 종양과 심막 침범 및 심장의 장측 심막에 위성 종양 등의 진행된 연골육종을 보였다. 수술은 종괴를 포함하여 양측 3개의 늑골, 양측 쇄골, 흉골자루와 흉막, 심막을 광범위 총괄절제하고, 2mm Gore-tex 포편과 광배근 자유 피부 근육판을 이용하여 흉벽을 재건하였다.

• Radiation Oncology Journal
• /
• 제34권1호
• /
• pp.1-9
• /
• 2016

Overexpression of human epidermal growth factor receptor 2 (HER2) is found in about 20% of breast cancer patients. With treatment using trastuzumab, an anti-HER2 monoclonal antibody, systemic control is improved. Nonetheless, the incidence of brain metastasis does not be improved, rather seems to be increased in HER2-positive breast cancer. The mainstay treatment for brain metastases is radiotherapy. According to the number of metastatic lesions and performance status of patients, radiosurgery or whole brain radiotherapy can be performed. The concurrent use of a radiosensitizer further improves intracranial control. Due to its large molecular weight, trastuzumab has a limited ability to cross the blood-brain barrier. However, small tyrosine kinase inhibitors such as lapatinib, has been noted to be a promising agent that can be used as a radiosensitizer to affect HER2-positive breast cancer. This review will outline general management of brain metastases and will focus on preclinical findings regarding the radiosensitizing effect of small molecule HER2 targeting agents.