• Title/Summary/Keyword: Neodiplostomum seoulensis

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The effect of reinfection with Neodiplostomum seoulensis on the histopathology and activities of brush border membrane bound enzymes in the rat small intestine (서울주걱흡충의 재감염이 흰쥐 소장의 조직병리 및 미소융모막효소 활성도에 미치는 영향)

  • 유재란;홍성태
    • Parasites, Hosts and Diseases
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    • v.33 no.1
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    • pp.37-44
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    • 1995
  • Neodiplostomum seoulensis, one of the human intestinal trematodes , was reinfected to albino rats, and worm recovery rates, histopathology and activity changes of the intestinal brush border membrane bound enzymes were observed. The experimental groups were three: uninfected, primary infection and reinfection. The worm recovery rate in the reinfection group was much lower than in the primary infection group 14 days after infection. The duodenal histopathology showed villous atrophy during the first and second week in the primary infection group. In the reinfection group, however. villous changes occurred as early as 3 days after the infection, and the lesion was found healed 7 days after infection. The activities of alkaline phosphatase and sucrase in the duodenum of primary infection rats decreased nearly half of the controls 2 weeks after infection, whereas the activities were unchanged in the reinfection group. However, no changes in the activities were observed in the proximal jejunum between the experimental groups. These findings suggested that a secondary infection of N. seouLensis in rats should make less damage on the intestinal mucosa than a primary infection. Key words: Neoniplostomum seoulensis, albino rats, reinfection, worm recovery, histopathology, brush border membrane bound enxyines.

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A follow-up examination of intestinal parasitic infections of the Army soldiers in Whachon-gun, Korea (화천군 소재 일부 장병의 장내 기생충 감염율과 호르텐스극구흡충, Neodiplostomum seoulensis의 감염예)

  • Sun Huh;Soo-Ung Lee;Seung-Chul Huh
    • Parasites, Hosts and Diseases
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    • v.32 no.1
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    • pp.61-63
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    • 1994
  • A follow-up stool examination was done to know the status of intestinal parasitic infections in Army soldiers who were stationing in Whachon-gun, Kangwon-do, Korea in 1993. Of 233 examined soldiers, Infections with Clonorchis sinensis (0.4%), Metagonimus spp. (0.9%), Echinostomc honene (0.4%), Neoniplostomum seodenis (0.4) and Ginrdin lomblic (3/233) were found. S. honene and N. seouLensis infections were each 75th, and 27th cases in Korea. Regular control program of intestinal parasitic Infections might be able to contribute to diminish the prevalence rate in young Army soldiers in Korea.

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IgA response in mice infected with Neodiplostomum seoulensis (서울주걱흡충 감염 마우스의 IgA 반응)

  • Sun HUH;Soo-Ung LEE;Moo-Ho WON;Young-Gil JEONG;Young-Hyun KWON;Chang sig CHOI
    • Parasites, Hosts and Diseases
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    • v.33 no.1
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    • pp.55-60
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    • 1995
  • To observe the production of IgA in Balb/c mice with neodiplostomiasis, 20 mice were infected with each 200 metacercariae of Neoniplostomum seoulenis. Sera and the duodenums were obtained 3, 7, 14, 28 days post-infection (PI) from five mice each group Neodipeostomum specific IgA in serum by the enzyme-linked immunosorbent assay increased from 7 days PI and persisted till 28 days PI. Immunohistochemistry for lgA was done with sections of the duodenum. The IgA-positive reaction was generally seen in the lamina propria and submucosa. Some of epithelial cells were positive at 7 and 14 days PI. The present finding showed that Neodiplostomun specific IgA antibody increased in serum and that there was local reaction of IgA in the mucosa and submucosa of the duodenum but not directly related with worm expulsion.

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