• Title/Summary/Keyword: Negative image

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Breast Tumor Cell Nuclei Segmentation in Histopathology Images using EfficientUnet++ and Multi-organ Transfer Learning

  • Dinh, Tuan Le;Kwon, Seong-Geun;Lee, Suk-Hwan;Kwon, Ki-Ryong
    • Journal of Korea Multimedia Society
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    • v.24 no.8
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    • pp.1000-1011
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    • 2021
  • In recent years, using Deep Learning methods to apply for medical and biomedical image analysis has seen many advancements. In clinical, using Deep Learning-based approaches for cancer image analysis is one of the key applications for cancer detection and treatment. However, the scarcity and shortage of labeling images make the task of cancer detection and analysis difficult to reach high accuracy. In 2015, the Unet model was introduced and gained much attention from researchers in the field. The success of Unet model is the ability to produce high accuracy with very few input images. Since the development of Unet, there are many variants and modifications of Unet related architecture. This paper proposes a new approach of using Unet++ with pretrained EfficientNet as backbone architecture for breast tumor cell nuclei segmentation and uses the multi-organ transfer learning approach to segment nuclei of breast tumor cells. We attempt to experiment and evaluate the performance of the network on the MonuSeg training dataset and Triple Negative Breast Cancer (TNBC) testing dataset, both are Hematoxylin and Eosin (H & E)-stained images. The results have shown that EfficientUnet++ architecture and the multi-organ transfer learning approach had outperformed other techniques and produced notable accuracy for breast tumor cell nuclei segmentation.

Acquisition and Interpretation Guidelines of Breast Diffusion-Weighted MRI (DW-MRI): Breast Imaging Study Group of Korean Society of Magnetic Resonance in Medicine Recommendations

  • Kang, Bong Joo;Kim, Min Jung;Shin, Hee Jung;Moon, Woo Kyung
    • Investigative Magnetic Resonance Imaging
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    • v.26 no.2
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    • pp.83-95
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    • 2022
  • The purpose of this study was to establish and provide guidelines for the standardized acquisition and interpretation of diffusion-weighted magnetic resonance imaging (DW-MRI) to improve the image quality and reduce the variability of the results interpretation. The standardized protocol includes the use of high-resolution DW-MRI with advanced techniques and post-processing. The aim of the protocol is to increase the effectiveness of the medical image information exchange involved in the construction, activation, and exchange of clinical information for healthcare use. An organized interpretation form could make DW-MRIs' interpretation easier and more familiar. Herein, the authors briefly review the basic principles, optimized image acquisition, standardized interpretation guidelines, false negative and false positive cases of DW-MRI, and provide a standard interpretation form and examples of various cases to help users become more familiar with the DW-MRI.

Usefulness of Superparamagnetic Iron Oxide (SPIO) as a Negative Oral Contrast Agent in MR Cholangiopancreatography (자기공명 담관췌장초영술에서 음성 경구 조영제로 사용한 초상자성 산화철 제재의 유용성)

  • 이정민;송원규;이종덕
    • Investigative Magnetic Resonance Imaging
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    • v.5 no.1
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    • pp.49-56
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    • 2001
  • Purpose : To evaluate value of superparamagnetic iron oxide (SPIO) as a negative oral contrast agent in MR cholangiopancreatography (MRCP). Materials and methods : Forty-eight patients with suspected biliary tract or pancreatic diseases and six healthy volunteers were enrolled in this study. All MR images were obtained using a 1.5 T MR unit. MR-CP using fat-suppressed half-Fourier acquisition single-shot turbo spin echo (HASTE) and turbo spin echo (TSE) techniques were performed and reconstructed with maximal intensity projection (MIP). To determine the most optimal concentration of SPIO to obliterate the high signal intensity of water, a phantom experiment was conducted with various concentrations of SPIO-water mixture. Two radiologists evaluated pre- and postcontrast MRCPS. The contrast enhancement was assessed on the basis of loss of signal intensity in the stomach and duodenum. Results : In the phantom experiment, a significant increase of percentage of signal intensity loss (PSIL) occurred in concentration of 22.4 ugFe/ml (Feridex1 ml diluted with water 500 ml). Postcontrast MRCP showed an improved image quality compared with precontrast images. The rate of improvement in the diagnosis of diseases of the common bile duct and pancreatic duct was 25% (12/48). Conclusion : In patients with suspected biliary tract and pancreatic diseases, the SPIO is useful as a negative oral contrast agent for MRCP and provides an improvement of image quality.

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Effect of Sales Promotion and the Consumer Product Evaluation: A Review and Synthesis

  • Park, Chul-Ju;Park, Jae-Sung
    • The Journal of Economics, Marketing and Management
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    • v.4 no.1
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    • pp.23-33
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    • 2016
  • Sales promotion is defined as the short-term incentive to encourage the purchase or sale of products and services. Retailers conduct a variety of sales promotion to encourage the purchase or sale of products and services. It is often used to induce the purchase of customers in short term and to improve the relationship with customers in the long term. Many previous studies about the effect of price discount SP on increase in sales and image improvement have conducted. But the study of non-price promotion, especially SP with 'Gifts', meanwhile, has been seldom researched. This study is to investigate the effect of the Gift SP conducted by retailers on the customer evaluation of the product and its Gifts. This study is to investigate the effect of 'Gifts', among the non-price promotion, on the customer evaluation. First of all, previous studies about the effect (-) of Sp with 'Gifts' on the customer evaluation of the product and its Gifts, and the factors that offset the negative effect of SP with 'Gifts' on quality perception are to examined. In this study, additionally, the summary of the study based on the previous studies and the research subject in the future are to be presented. Firstly, to examine the previous researches on the effect of SP which retailers conduct on the increased sales and or enhanced image, price discount SP has attracted a lot of attention as a research subject but researches on non-price sales promotion, particularly on SP with gift have seldom conducted as a research subject. Secondly, in the previous studies relevant to Price Discount SP, the long-term negative (-) effect of the target product or brand of SP has been studied. However, a few researches on the long-term negative (-) effect of SP with gift have been conducted. Thirdly, it might be brand affinity and purchase limit that buffered the negative (-) effect on the perceived quality of SP with gift which retailers had conducted. In spite of various studies conducted by many researchers, each study have discussed the consequences under certain circumstances and integrated results of research have not been in progress. It may be the research issues left to us to clearly identify the psychological mechanism of consumers until the effect of SP happens in order to theorize SP and to present a practical and useful suggestion.

The Comparison of Fabric Images between On-line and Off-line by Fabric Types and Characteristics (직물의 종류와 특성에 따른 온라인과 오프라인에서의 의복소재 이미지 비교)

  • Kim, Hee-Sook;Cho, Shin-Hyun
    • Korean Journal of Human Ecology
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    • v.13 no.5
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    • pp.787-798
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    • 2004
  • This research was designed to compare clothing fabric images between on- and off-line by fabric types and its characteristics. 125 subjects who have a fashion design major evaluated the fabric image of various 16 kinds of specimens on- and off-line. Frequency, x2-test, t-test, and Pearson correlation were used for statistical analysis by SPSS WIN 11.0. The results of this study are as follows: 1. The advantage of on-line shopping includes low price and purchasing convenience, etc. On-line shoppers mostly purchase clothing items, such as T-shirt and slacks. In most cases, texture of fabrics provides a main cause for the shoppers' discontentment with internet shopping. 2. The results of t-test for the difference of the evaluation score show that plain or pile weave and highly thick or thin fabrics-for example, Organdy, Corduroy, Nylon Taffeta, Plush, etc.-have a large difference between on-and off-line image. On the other hand, medium-thick twill weave-for example, Tweed, Flannel, etc.-or patterned weave-Chiffon, Dobby fabric, etc.-shows a small difference. 3. The results of correlation of the evaluation score indicate that wool twill fabrics like Tweed, Saxony, and Polafleece show a high correlation between two kinds of evaluation score. In texture preference, no correlation exists between on-line and off-line. 4. With an analysis on fabric image evaluation by fabric characteristics, smooth, shiny pink Satin was found the most positively-evaluated item in all evaluation fields except in pattern preference and individuality. On the other hand, thick olive green Corduroy was evaluated most negatively in the fields of elegance, luxury, and feminine. 5. When compared with real ones, thin fabrics provide a different on-line fabric image. For example, Nylon Taffeta and Organdy were evaluated positively on-line because of luster and pastel tone color. However, lusterless uneven cotton Seersucker was evaluated negatively. 6. Real fabrics preference is more negative than on-line ones. In addition, patterned or unique fabrics display a high agreement between the two kinds of images.

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The Effects of Country-Related Affect on Consumers' Purchase Intention: Focusing on the Moderating Roles of Market Entry Modes (국가 관련 감정이 소비자들의 구매의도에 미치는 영향: 해외진입방식의 조절효과를 중심으로)

  • Li, Wei;Oh, Han-Mo
    • Asia-Pacific Journal of Business
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    • v.7 no.1
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    • pp.59-69
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    • 2016
  • An extensive body of research on the effects of country-of-origin has emerged in the international marketing and business literature streams. Nonetheless, extant studies do not satisfactorily demonstrate whether and how a foreign firm's choice of market entry mode influences consumers' purchase intentions of its product in country-related affect contexts. Using a survey and an experimental design, we aimed to provide evidence of the effects of the choice on consumers' evaluation and attitude of its product in an animosity context and in a national image context. Through the survey, we collected data regarding consumer animosity, national image, product evaluation, and product attitude from 185 university students and tested the hypotheses that consumer animosity and national image have effects on foreign product evaluation and attitude. The results of the survey research show that personal animosity has a negative effect on consumers' evaluation of foreign products and that a country's image regarding economics has positive effects on consumers' attitude toward foreign products as well as consumers' evaluation of foreign products. In the experimental design, we divided subjects into four groups and exposed them to several descriptions of hypothetical purchase situations. Conducting a 2 (market entry modes)${\times}2$ (country-of-origin) ANOVA, we tested the hypothesis that a market entry mode influences foreign product evaluation and attitude. The results of the experimental study reveal that in a high country-related product association (Germany), market entry modes have insignificant effects on foreign product evaluation and attitude. In addition, in a low country-related product association (China), international partnership has more positive effects on foreign product evaluation and attitude than does exporting.

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Computerized Image Analysis of Micronucleated Reticulocytes in Mouse Bone Marrow (컴퓨터 이미지 분석법을 이용한 마우스 골수세포에서 소핵의 계수)

  • 권정;홍미영;고우석;정문구;이미가엘
    • Toxicological Research
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    • v.18 no.4
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    • pp.369-374
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    • 2002
  • The present study was performed to validate an automated image analysis system (Loats Automated Micronucleus Scoring System) for the mouse bone marrow micronucleus assay, comparing with conventional microscopic scoring. Two studies were conducted to provide slides for a comparison of micro-nucleated polychromatic erythrocytes (MNPCEs) values collected manually to those collected by the auto-mated system. Test article A was used as an example of a compound negative for the induction of micronuclei and test article B was wed as a micronucleus-inducing agent to elicit a positive response. Cyclophosphamide was included to provide an positive control in two studies. Bone marrow samples were collected 24 h after administration of test article A and B in male ICR mice. The cells were fixed with absolute methanol and stained with May-Grunwald and Giemsa. The number of MNPCEs was determined by the analysis of 1000 total PCEs per bone marrow sample. In addition to micronucleus scoring, an index of bone marrow toxicity based on PCE ratio (% of PCEs to total erythrocytes) was determined for each sample. The automated and manual scoring was similar when the MNPCEs incidence induced by each test article was less than 10. However manual scoring was able to effectively enumerate micronucleated PCEs in mouse bone marrow when MNPCEs incidence was more than 10, such as cyclophosphamide treatment. Conversely, PCE ratio was superior in computer-assisted image analysis. Taken together, it is suggested that improvement of the automated image analysis may be necessary to render the automatic scoring as sensitive as manual scoring for routine counting of micronuclei, especially because it is superior in objectivity and high throughput scoring.

Emotion Image Retrieval through Query Emotion Descriptor and Relevance Feedback (질의 감성 표시자와 유사도 피드백을 이용한 감성 영상 검색)

  • Yoo Hun-Woo
    • Journal of KIISE:Software and Applications
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    • v.32 no.3
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    • pp.141-152
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    • 2005
  • A new emotion-based image retrieval method is proposed in this paper. Query emotion descriptors called query color code and query gray code are designed based on the human evaluation on 13 emotions('like', 'beautiful', 'natural', 'dynamic', 'warm', 'gay', 'cheerful', 'unstable', 'light' 'strong', 'gaudy' 'hard', 'heavy') when 30 random patterns with different color, intensity, and dot sizes are presented. For emotion image retrieval, once a query emotion is selected, associated query color code and query gray code are selected. Next, DB color code and DB gray code that capture color and, intensify and dot size are extracted in each database image and a matching process between two color codes and between two gray codes are peformed to retrieve relevant emotion images. Also, a new relevance feedback method is proposed. The method incorporates human intention in the retrieval process by dynamically updating weights of the query and DB color codes and weights of an intra query color code. For the experiments over 450 images, the number of positive images was higher than that of negative images at the initial query and increased according to the relevance feedback.

The Operational Comparison of SPOT GCP Acquisition and Accuracy Evaluation

  • Kim, Kam-Lae;Kim, Uk-Nam;Chun, Ho-Woun;Lee, Ho-Nam
    • Korean Journal of Geomatics
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    • v.1 no.1
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    • pp.1-5
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    • 2001
  • This paper presents an investigation into the operational comparison of SPOT triangulation to build GCP library by analytical plotter and DPW (digital photogrammetric workstation). GCP database derived from current SPOT images can be used to other image sensors of satellite, if any reasons, such as lack of topographic maps or GCPs. But, general formulation of a photogrammetric process for GCP measurement has to take care of the scene interpretation problem. There are two classical methods depending on whether an analytical plotter or DPW is being used. Regardless of the method used, the measurement of GCPs is the weakest point in the automation of photogrammetric orientation procedures. To make an operational comparison, five models of SPOT panchromatic images (level 1A) and negative films (level 1AP) were used. Ten images and film products were used for the five GRS areas. Photogrammetric measurements were carried out in a manual mode on P2 analytical plotter and LH Systems DPW770. We presented an approach for exterior orientation of SPOT images, which was based on the use of approximately eighty national geodetic control points as GCPs which located on the summit of the mountain. Using sixteen well-spaced geodetic control points per model, all segments consistently showed RMS error just below the pixel at the check points in analytical instrument. In the case of DPW, half of the ground controls could not found or distinguished exactly when we displayed the image on the computer monitor. Experiment results showed that the RMS errors with DPW test was fluctuated case by case. And the magnitudes of the errors were reached more than three pixels due to the lack of image interpretation capability. It showed that the geodetic control points is not suitable as the ground control points in DPW for modeling the SPOT image.

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The Characteristics of Obesity-Related Factors, Perceptions of Body Image, and Psychological Eating Behaviors in Married Obese Women Living in the Seoul Area (서울 근교 지역에 거주하는 비만 여성의 비만 관련 요인, 체형 인지도 및 심리적 섭식 행동)

  • Ha, Ae-Wha;Han, In-Kyung
    • Journal of the East Asian Society of Dietary Life
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    • v.19 no.3
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    • pp.327-338
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    • 2009
  • The purpose of this study was to obtain information from married women regarding obesity-related factors and psychological eating behaviors, and to compare those variables among three groups, namely underweight, normal, and obese. The participants completed questionnaires regarding general obesity-related factors, major food servings/day, physical activity, dieting behaviors, perceptions of body image, and psychological eating behaviors. The results were as follows: The obese women reported a higher percentage of family history of obesity (74.8%) than the normal (43.5%) or underweight (28.2%) women. Most of the obese women (90.0%) accurately perceived their body image compared to 72.5% of the underweight and 56.6% of the normal weight women(p<0.001). No significant differences were found among the three groups for daily hours of exercise or computer use. In the case of hours of television watched daily, significant differences were found among the groups (obese 104 min/day, normal 87 min/day, underweight 76/min, p<0.05). Only 17.9% of the obese women reported eating 2 servings of milk products/day and only 23.2% of them reported eating 3 servings of protein foods/day as compared to the normal (25.4%, 18.0%) and underweight (29.4%, 41.7%) (p<0.01) women. About 98% of the obese and 78.5% of the normal weight women wanted to loose weight compared to only 10% of the underweight women (p<0.001). Psychological eating behavior was significantly correlated with subject BMI ($r^2$=0.32, p<0.01). Also, more obese women were unsatisfied with their body and had emotional eating behaviors as compared to the normal and underweight women, and this was statistically significant (p<0.001). In conclusion, the obese women had high perception rates of their body image, but had negative-psychological eating behaviors. Special behavior therapy is needed for obese women who show body dissatisfaction, emotional eating behaviors, long hours of daily TV viewing, and low intakes of protein and milk products.

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