• Title/Summary/Keyword: Near Seoul

Search Result 1,861, Processing Time 0.036 seconds

Genome-wide Association Study of Integrated Meat Quality-related Traits of the Duroc Pig Breed

  • Lee, Taeheon;Shin, Dong-Hyun;Cho, Seoae;Kang, Hyun Sung;Kim, Sung Hoon;Lee, Hak-Kyo;Kim, Heebal;Seo, Kang-Seok
    • Asian-Australasian Journal of Animal Sciences
    • /
    • v.27 no.3
    • /
    • pp.303-309
    • /
    • 2014
  • The increasing importance of meat quality has implications for animal breeding programs. Research has revealed much about the genetic background of pigs, and many studies have revealed the importance of various genetic factors. Since meat quality is a complex trait which is affected by many factors, consideration of the overall phenotype is very useful to study meat quality. For integrating the phenotypes, we used principle component analysis (PCA). The significant SNPs refer to results of the GRAMMAR method against PC1, PC2 and PC3 of 14 meat quality traits of 181 Duroc pigs. The Genome-wide association study (GWAS) found 26 potential SNPs affecting various meat quality traits. The loci identified are located in or near 23 genes. The SNPs associated with meat quality are in or near five genes (ANK1, BMP6, SHH, PIP4K2A, and FOXN2) and have been reported previously. Twenty-five of the significant SNPs also located in meat quality-related QTL regions, these result supported the QTL effect indirectly. Each single gene typically affects multiple traits. Therefore, it is a useful approach to use integrated traits for the various traits at the same time. This innovative approach using integrated traits could be applied on other GWAS of complex-traits including meat-quality, and the results will contribute to improving meat-quality of pork.

Muscular invasion by oral squamous cell carcinoma of the posterior mandibular alveolar ridge is associated with cervical lymph node metastasis

  • Min, Seung-Ki;Myoung, Hoon;Lee, Jong-Ho;Kim, Myung-Jin
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
    • /
    • v.42 no.3
    • /
    • pp.133-138
    • /
    • 2016
  • Objectives: To assess the association between muscle invasion by oral squamous cell carcinoma of the posterior mandibular alveolar ridge and cervical lymph node metastasis on the basis of preoperative magnetic resonance imaging (MRI). Materials and Methods: Twenty-six patients with oral squamous cell carcinoma of the posterior mandibular alveolar ridge were evaluated by MRI. The associations between cervical lymph node metastasis and independent factors evaluated by MRI were analyzed. Overall survival was also analyzed in this manner. Representative biopsy specimens were stained with anti-podoplanin and anti-CD34 antibodies. Results: Mylohyoid muscle invasion was associated with cervical lymph node metastasis. A combinational factor of mylohyoid and/or buccinator muscle invasion was also associated with cervical lymph node metastasis. Cervical lymph node metastasis and masticator space invasion had a negative effect on overall survival. No lymphatic vessels were identified near the tumor invasion front within the mandible. In contrast, lymphatic vessels were identified near the front of tumor invasion in the muscles. Conclusion: This study demonstrates an association between muscular invasion by oral squamous cell carcinoma of the posterior mandibular alveolar ridge and cervical lymph node metastasis.

Observation of Discharge Mode Transient from Townsend to Glow at Breakdown of Helium Atmospheric Pressure Dielectric Barrier Discharge (헬륨 대기압 유전체 격벽 방전기의 타운젠트-글로우 방전 모드 전이 연구)

  • Bae, Byeongjun;Kim, Nam-Kyun;Yoon, Sung-Young;Shin, Jun-Seop;Kim, Gon-Ho
    • Journal of the Semiconductor & Display Technology
    • /
    • v.15 no.2
    • /
    • pp.26-31
    • /
    • 2016
  • The Townsend to glow discharge mode transition was investigated in the dielectric barrier discharge (DBD) helium plasma source which was powered by 20 kHz / $4.5 kV_{rms}$ high voltage at atmospheric pressure. The spatial profile of the electric field strength at each modes was measured by using the intensity ratio method of two helium emission lines (667.8 nm ($3^1D{\rightarrow}2^1P$) and 728.1 nm ($3^1S{\rightarrow}2^1P$)) and the Stark effect. ICCD images were analyzed with consideration for the electric field property. The Townsend discharge (TD) mode at the initial stage of breakdown has the light emission region located in the vicinity of the anode. The electric field of the light emitting region is close to the applied field in the system. Immediately, the light emitting region moves to the cathode and the discharge transits to the glow discharge (GD) mode. This mode transition can be understood with the ionization wave propagation. The electric field of the emitting region of GD near cathode is higher than that of TD near anode because of the cathode fall formation. This observation may apply to designing a DBD process system and to analysis of the process treatment results.

Decision Support System Design for GIS based Construction Planning of Urban Railroad (GIS를 이용한 도시철도 건설계획수립을 위한 의사결정지원시스템 설계에 관한 연구)

  • Oh Yoon-Seuk;Koo Jee-Hee;Kim Tae-Hoon
    • Spatial Information Research
    • /
    • v.13 no.2 s.33
    • /
    • pp.139-155
    • /
    • 2005
  • Today, ever growing population density in Seoul or areas near Seoul is problematic. To overcome the problem, the government tries to construct so called, 'New-towns'near Seoul to spread out the population over larger areas. But building new-towns created another problem of traffic between Seoul and New-towns. It can be solved if more public transportation systems such as urban railroads are constructed. In order to succeed in urban railroad construction, we have to make a perfect plan through in depth research on characteristics of the urban train and the construction site. In this paper, we propose a method to design the Decision Support Systems(DSS) using Geographic Information Systems(GIS) and Spatial Analysis for the planning of urban railroad construction.

  • PDF

Organic amendment-driven removal and speciation of metals using wormwood in two contrasting soils near an abandoned copper mine

  • Ro, Hee-Myong;Choi, Hyo-Jung;Yun, Seok-In;Park, Ji-Suk
    • Horticulture, Environment, and Biotechnology : HEB
    • /
    • v.59 no.6
    • /
    • pp.775-786
    • /
    • 2018
  • To test the hypothesis that humic acid (HA), anaerobically digested pig slurry filtrate (APS), and their combination would differently affect the chemical speciation and extractability of metals (cadmium, copper, and zinc) and their uptake by plants, we conducted a pot experiment using wormwood in two texturally contrasting soils (sandy loam and clay loam) collected from a field near an abandoned Cu mine. Four treatments were laid out: HA at $ 23.5g\;kg^{-1}$ (HA), APS at $330mL\;kg^{-1}$ (APS), HA at $ 23.5g\;kg^{-1}$ and APS at $330mL\;kg^{-1}$ (HA + APS), and a control. Each treatment affected the chemical speciation and mobility of the metals, and thereby resulting in variable patterns of plant biomass yield and metal uptake. The APS supported plant growth by increasing nutrient availability. HA supported or hindered plant growth by impacting the soil's water and nutrient retention capacity and aeration, in a soil texture-dependent manner, while consistently enhancing the immobilization of heavy metals. Temporal increases in whole-plant dry matter yield and metal accumulation suggested that the plants were capable of metal hyperaccumulation. The results were discussed in terms of the mobility of metals and plant growth and corroborated by the $^{15}N$ recovery of soil- and plant-N pools under H and HS treatments. Therefore, for effective phytoremediation of polluted soils, an appropriate combination of plant growth promoters (APS) and chelating agents (HA) should be predetermined at the site where chemical stabilization of pollutants is desired.

Circumstellar Clumps in the Cassiopeia A Supernova Remnant: Prepared to be Shocked

  • Koo, Bon-Chul;Kim, Hyun-Jeong;Oh, Heeyoung;Raymond, John C.;Yoon, Sung-Chul;Lee, Yong-Hyun;Jaffe, Daniel T.
    • The Bulletin of The Korean Astronomical Society
    • /
    • v.45 no.1
    • /
    • pp.43.1-43.1
    • /
    • 2020
  • Cassiopeia A (Cas A) is a young supernova remnant (SNR) where we observe the interaction of SNR blast wave with circumstellar medium. From the early optical studies, dense, slowly-moving, N-rich "quasi-stationary flocculi" (QSF) have been known. These are probably dense CNO-processed circumstellar knots that have been engulfed by the SNR blast wave. We have carried out near-infrared, high-resolution (R=45,000) spectroscopic observations of ~40 QSF, and here we present the result on a QSF knot (hereafter 'Knot 24') near the SNR boundary of Cas A. The average [Fe II] 1.644 um spectrum of Knot 24 has a remarkable shape with a narrow (~8 km/s) line superposed on the broad (~200 km/s) line emitted from shocked gas. The spatial morphology and the line parameters indicate that Knot 24 has been partially destroyed by a shock wave and that the narrow line is emitted from the unshocked material heated/ionized by the shock radiation. This is the first detection of the emission from the pristine circumstellar material of the Cas A supernova progenitor. We also detected H Br gamma and other [Fe II] lines corresponding to the narrow [Fe II] 1.644 um line. For the main clump where we can clearly identify the shock emission associated with the unshocked material, we analyze the observed line ratios using a shock model that includes radiative precursor. The analysis indicates that the majority of Fe in the unshocked material is in the gas phase, not depleted onto dust grains as in the general interstellar medium. We discuss the non-depletion of Fe in QSF and its implications on the immediate progenitor of the Cas A supernova.

  • PDF

Influence of Environmental Exposures on Patients with Chronic Obstructive Pulmonary Disease in Korea

  • Hong, Yoonki;Lim, Myoung Nam;Kim, Woo Jin;Rhee, Chin Kook;Yoo, Kwang Ha;Lee, Ji-Hyun;Yoon, Ho Il;Kim, Tae-Hyung;Lee, Jin Hwa;Lim, Seong Yong;Lee, Sang Do;Oh, Yeon-Mok
    • Tuberculosis and Respiratory Diseases
    • /
    • v.76 no.5
    • /
    • pp.226-232
    • /
    • 2014
  • Background: Chronic obstructive pulmonary disease (COPD) is characterized by airflow limitation and results from environmental factors and genetic factors. Although cigarette smoking is a major risk factor, other environmental exposures can influence COPD. The purpose of this study is to investigate the clinical characteristics of COPD according to the history of environmental exposure. Methods: The study population comprised of 347 subjects with COPD who were recruited from the pulmonary clinics of 14 hospitals within the Korean Obstructive Lung Disease Study Group. We classified environmental exposures according to history of living near factory, and direct exposure history to firewood or briquette. According to living environmental exposures, we compared the frequency of respiratory symptoms, pulmonary function, quality of life, exercise capacity, and computed tomography phenotypes. Results: Thirty-one subjects (8.9%) had history of living near factory, 271 (78.3%) had exposure history to briquette, and 184 (53.3%) had exposure history to firewood. Patients with history of living near a factory had a significantly longer duration of sputum, while patients with exposure to firewood tended to have lower forced expiratory volume in one second, and patients with exposure to briquette tended to have lower six minute walk distance. Conclusion: COPD subjects with the history of living near factory had more frequent respiratory symptoms such as sputum. Our data suggest that environmental exposure may influence clinical phenotype of COPD.

Study on the Health Status of the Residents near Military Airbases in Pyeongtaek City (평택시 군용비행장 주변지역 주민건강조사)

  • Kim, Hyun-Joo;Roh, Sang-Chul;Kwon, Ho-Jang;Paik, Ki-Chung;Rhee, Moo-Yong;Jeong, Jae-Yun;Lim, Myung-Ho;Koo, Mi-Jin;Kim, Chang-Hoon;Kim, Hae-Young;Lim, Jeong-Hun;Kim, Dong-Hyun
    • Journal of Preventive Medicine and Public Health
    • /
    • v.41 no.5
    • /
    • pp.307-314
    • /
    • 2008
  • Objectives : We conducted an epidemiologic survey to evaluate the effect of the aircraft noise exposure on the health of the residents near the military airbases in Pyeongtaek City. Methods : The evaluation of environmental noise level, questionnaire survey, and health examination were performed for 917 residents. The study population consisted of four groups: subjects who lived in the village close to the fighter airbase (high exposure), subjects who lived along the course of fighters (intermediate exposure), and subjects near a helicopter airbase, and the control group. Results : The prevalence of the aircraft noise related accident and irritable bowel syndrome in the exposure groups were higher than that of the control group. The risks of noise induced hearing loss, hypertension and diabetes mellitus were higher in the exposed groups than in the control group. The prevalence of anxiety disorder and primary insomnia were higher in the exposed groups than in the control group. Prevalence odd ratios of the risk for primary insomnia after adjusting age, sex, agricultural noise, and occupation were 4.03 [95% confidence interval (95% Cl) 1.56-10.47] for the subject near the helicopter airbase, 1.23 (95% Cl 0.40-3.76) for those intermediately exposed to fighter noise, and 4.99 (95% Cl 2.14-11.64) for those highly exposed to fighter noise. Conclusions : The results of the present study suggest that the aircraft noise may have adverse effects on hearing function, cardiovascular health and mental health. Therefore, it seems to be needed to take proper measures including the control of the aircraft noise and the management of the exposed people's health.

Response Analysis of RC Bridge Pier with Various Superstructure Mass under Near-Fault Ground Motion (근단층지반운동에 대한 상부구조 질량 변화에 따른 RC 교각의 응답분석)

  • Park, Chang-Kyu;Chung, Young-Soo;Lee, Dae-Hyung
    • Journal of the Korea Concrete Institute
    • /
    • v.22 no.5
    • /
    • pp.667-673
    • /
    • 2010
  • The near fault ground motion (NFGM) is characterized by a single long period velocity pulse with large magnitude. NFGMs have been observed in recent strong earthquakes, Northridge (1994), Japan Kobe (1995), Turkey Izmit (1999), China Sichuan (2008), Haiti (2010) etc. These strong earthquakes have caused considerable damage to infrastructures because the epicenter was close to the urban area, called as NFGM. Extensive research for the far field ground motion (FFGM) have been carried out in strong seismic region, but limited research have been done for NFGM in low or moderate seismic regions because of very few records. The purpose of this research is to investigate and analyze the seismic response of reinforced concrete bridge piers subjected to near-fault ground motions. The seismic performance of six RC bridge piers depending on three confinement steel ratios and three superstructure mass was investigated on the shaking table. From these experimental results, it was confirmed that the reduction of seismic performance was observed for test specimens with lower confinement steel ratio or more deck weight. The displacement ductility of RC bridge piers in terms of the stiffness degradation is proposed based on test results the shaking table.

AN ACCURATE AND EFFICIENT CALCULATION OF HIGH ENTHALPY FLOWS USING A HIGH ORDER NEW LIMITING PROCESS

  • Noh, Sung-Jun;Lee, Kyung-Rock;Park, Jung-Ho;Kim, Kyu-Hong
    • Journal of the Korean Society for Industrial and Applied Mathematics
    • /
    • v.15 no.1
    • /
    • pp.67-82
    • /
    • 2011
  • Calculation of accurate wall heat flux for high enthalpy flows requires a dense grid system, which leads to significantly large computational time. A high-order scheme can improve the efficiency of calculation because wall heat flux can be obtained accurately even with a relatively coarse grid system. However, conventional high order schemes have some drawbacks such as oscillations near a discontinuity and instability in multi-dimensional problem. To resolve these problems, enhanced Multi-dimensional Limiting Process(e-MLP) was applied as a high-order scheme. It could provide robust and accurate solutions with high order accuracy in calculation of high enthalpy flows within a short time. We could confirm the efficiency of the high order e-MLP scheme through grid convergence tests with different grid densities in a hypersonic blunt nose problem.