• Title/Summary/Keyword: Nature of Medicine

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Protective Immune Reponses Induced by Non-infectious L-particles of Equine Herpesvirus Type-1: Implication of Cellular Immunity

  • Mohd Lila Mohd Azmi;Field, Hugh-John;Frazer Rixon;Lauchlan, John-Mc
    • Journal of Microbiology
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    • v.40 no.1
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    • pp.11-19
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    • 2002
  • Mice immunized with equine herpesvirus type-1(EHV-1) L-particles skewed a significant increase (p<7.75) in serum antibody titers. Upon a booster dose four weeks lateral antibody titers increased significantly. Interestingly, immunization via intravenous or intramuscular route induced significantly higher (p<0.75) antibody titers. However, mice iummunized with UV-treated L-particles, visions or immunization via intranasal route induced lower antibody titers. Upon challenge inoculation with wildtype EHV-1, our data showed there was a poor correlation between antibody titers and protection against virus replication. Therefore, the role of cell-mediated immunity Inwards protection was investigated. As predicted, the strongest cell-mediated immunity, as measured by delayed-hypersensitivity test, was detected in mice immunized with live virus particles. The magnitude of cell-mediated immune response correlated with the efficacy of L-particles as immunizing agent. The highest efficacy, as indicated in mice immunized via intranasal routed was highly correlated with cell-mediated immunity. A similar phenomenon was also demonstrated in mice immunized intranasally with UV-treated L-particles. However, the degree of protection was reduced when mice immunized intravenously or intramuscularly with UV-treated L-particles. In conclusion, protection conferred in these animals was highly implicated by immune cells and the least by antibodies. The route of immunization and the nature of the antigen also contributed to the efficacy of L-particles as immunizing agent. In contrast to that of herpes simplex virus type 1, our data showed EHV-1 non-infectious L-particles are highly suitable for immunization of the host against EHV-1 disease.

A Study on the Type of Hospital Nurses' Professional Nursing Image;A Q-methodological Approach (간호사의 전문간호이미지 유형에 관한 연구;Q - 방법론적 접근)

  • Yoon, Eun-Ja
    • Journal of Korean Academy of Nursing Administration
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    • v.2 no.2
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    • pp.17-42
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    • 1996
  • Most human behaviors are based on self-perceptual image. Subjectivity in professional nursing image is shown in their opinions, beliefs, values, and attitudes of professional nursing and it helps to understand individual's behavior. This study was initiated to find the characteristics and patterns in subjectivity of hospital nurses' professional nursing image. The Data were collected from Apr. 20 to Aug. 22, 1996. The research method employed Q-methodology which is based on self-psychology and abductive logics. Analysis of Q-type obtained by QUANL pc program. The characteristics of professional nursing image was analyzed based on the typal array, extreme comments, and the subject's demographic information. The results revealed that there are three different types on the professional nursing image. The three types were named as follows : The first type, the Improvable, consisting of 6 subjects, preferentially perceived nursing is human behavior as life process, coordinating with other health personnel for the patients as nurses' important role. On the other hand, they are taking a little dissatisfied view of professional nursing image, which can be estimated to advance for the construction of the professional nursing image. The second type, the Self-conflicted, consisting of 13 subjects, who have the subjectivity of the image by focusing on external and environmental factors rather than developing positive individual nurses' image for their profession. They have very conflic-ting and self-degrading traits. The third type, the Affirmative, consisting of 10 subjects, who appreciate the essence of nursing, and that they highly perceived nurse' positive attitude, devotion, mature interrelationship and self-developing efforts etc. In conclusion, this study discovers three types on the professional nursing image and their relationship. By identifying the nature of three types, this study suggests that the results should be useful reinforcement tool in educating nursing students as well as in continuing education for hospital nurses.

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Inhibitory effect of dietary turmeric (Curcuma longa L.) ethanol extract on DMBA-induced mammary carcinogenesis in rats (울금 투여에 의한 DMBA 유발 랫드 유선암화과정 억제효과)

  • Kim, Min Sook;Jeong, Kyu Shik;You, Mi-Kyoung;Kim, Hyeon-A
    • Food Science and Preservation
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    • v.21 no.3
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    • pp.301-307
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    • 2014
  • The purpose of this study was to examine the potential of turmeric (Curcuma longa L.) to inhibit 7,12-dimethylbenz[a]anthracene (DMBA)-induced mammary carcinogenesis in rats. Female Sprague Dawley rats were fed a control diet (NC and DC) or an ethanol extract of turmeric (DT) diet until the end of the experiment. The rats in the DC and DT groups were administered a single dose of DMBA (50 mg/Kg) by oral gavages at 50 days of age. The turmeric ethanol extracts decreased the incidence and multiplicity of DMBA-induced mammary tumor. The turmeric ethanol extract significantly decreased the tumor cell proliferation. The turmeric also significantly decreased the tumor grade based on the degree of the tubule formation. The results suggest that the ethanol extract of turmeric has an inhibitory effect against mammary carcinogenesis, and that such chemopreventive effect may be related to the inhibition of the initiation and the proliferation of tumor cells.

Effect of Social-Economic Factors and Related factors of Health and Life-Style on Health Foods Intakes among the Middle Aged in the Jeonbuk Region (전북 일부지역 중년의 사회 경제적 요인, 건강 및 생활 관련인자가 건강식품 섭취에 미치는 영향)

  • 장혜순;김미라
    • Korean Journal of Community Nutrition
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    • v.6 no.4
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    • pp.617-627
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    • 2001
  • This study examined health foods intakes and related variables among the middle aged(150 men and 159 women) in the Jeonbuk region. Health foods were classified into 4 groups including Chinese medicine(CM), toner foods(TF), vitamin or mineral supplements(VMS), and other manufactured health food supplements(MHFS). The number of people taking health foods were higher for those in their 50's than in their 40's. The consumption rate of TF in men was the highest among health foods, this result had significance. The reasons for taking health foods were recovery from fatigue, supplement of nutrients and making smooth body activity in general, but TF was used to increase of vigor. The consumption rate of health foods was a little different according to social-economic factors, namely, the consumption rate of CM was higher in people in rural than urban areas, those who graduated from middle school than university, blue color & self-employed as opposed to housewives and service workers, low level income than high level income, and Buddhism and no religion than Christian. The consumption rate had a correlation with the habits of smoking, alcohol drinking and exercise ; namely, the consumption rate of CM was higher than VMS and MHFS on smokers and alcohol drinkers. The more the frequency of exercise, the higher the consumption rate of TF, but the duration of the exercise was not correlated. This study suggests that middle aged people need nutritional education for the right recognition and selection of health foods and to consider the nature of each type of health foods.

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Detection and Phylogenetic Analysis of Viruses Linked with Fig Mosaic Disease in Seventeen Fig Cultivars in Palestine

  • Jamous, Rana Majed;Zaitoun, Salam Yousef Abu;Mallah, Omar Bassam;Shtaya, Munqez;Elbeaino, Toufic;Ali-Shtayeh, Mohammed Saleem
    • The Plant Pathology Journal
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    • v.36 no.3
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    • pp.267-279
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    • 2020
  • Fig mosaic is a viral disease (FMD) that spreads in Palestinian common fig (Ficus carica L.) orchards. Recognizing the economic value of fig plants and the harmful nature of FMD, the disease poses a significant threat to the economy of the fig production in Palestine. We applied the reverse transcription and amplification (RT-PCR) and PCR technique to leaf samples of 77 trees and 14 seedlings of 17 fig cultivars. The samples were collected from orchards in the main fig-growing provinces of the Palestinian West Bank, to assess the prevalence of viruses associated with FMD, and confirm a possible link of symptoms with viruses detected. Four viruses were detected: Fig mosaic virus (FMV), Fig badnavirus-1 (FBV-1), Fig leaf mottle-associated virus 2 (FLMaV-2), and Fig fleck-associated virus (FFkaV). FMV and FBV-1 were found in all tested fig plants (100%), while FLMaV-2 and FFkaV were detected in 61.5% and 33% of the fig samples, respectively. The high incidence of FBV-1 in the newly propagated symptomatic and symptomless seedlings from different cultivars may be an indication that FBV-1 is integrated into the genome of the fig in a cultivar nondiscriminatory manner. Very weak or no association was detected between FMD symptoms severity in the 17 Palestinian fig cultivars with the various viruses' combinations observed (i.e., number of the viruses infecting the plant). These results support the notion that FMD symptom severity expression is likely to be controlled by a combination of FMV infection, cultivars, and environmental factors, rather than the number of viruses infecting the plant.

Naturopathy Theory and Mechanism of Breathing Massage for Life Care (라이프 케어를 위한 호흡마사지법의 자연치유 이론기전)

  • Kim, Meong-Ju;Kim, Hye-Jeong
    • Journal of the Korean Applied Science and Technology
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    • v.34 no.4
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    • pp.1104-1111
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    • 2017
  • In this study, the authors aimed to give careful consideration to the circulation of bioenergy (Qi) by using cardiorespiratory massage technique. Finding enlightenment in harmony with nature thousands of years ago, our ancestors created Qi using natural breathing and tried to achieve good health and long life by controling the up and down movement. Experiencing the importance of the abdomen during the hungry times, also, grandmothers cured diseases by rubbing the abdomen, which is the ocean of life with their soft, soothing touch of hand. Naval breathing therapy was formed, based on natural breathing, emotional recognition of grandmothers' soft, soothing touch, and the Theory of Unified Reason and Energy that is the key of Oriental medicine. Natural breathing and Yakson massage are kinds of naturopathy to change body and mind, cure diseases naturally, and maintain the improvement in physical functions by taking care of the abdomen through the creation of Qi and the up and down movement and keeping dynamic balance between the natural world and the inside and outside of human body. It is anticipated that this study could contribute to the practical spread for an active application of naval breathing therapy and be broadly used in scientific clinical researches.

Quality Assurance of Patients for Intensity Modulated Radiation Therapy (세기조절방사선치료(IMRT) 환자의 QA)

  • Yoon Sang Min;Yi Byong Yong;Choi Eun Kyung;Kim Jong Hoon;Ahn Seung Do;Lee Sang-Wook
    • Radiation Oncology Journal
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    • v.20 no.1
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    • pp.81-90
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    • 2002
  • Purpose : To establish and verify the proper and the practical IMRT (Intensity--modulated radiation therapy) patient QA (Quality Assurance). Materials and Methods : An IMRT QA which consists of 3 steps and 16 items were designed and examined the validity of the program by applying to 9 patients, 12 IMRT cases of various sites. The three step OA program consists of RTP related QA, treatment information flow QA, and a treatment delivery QA procedure. The evaluation of organ constraints, the validity of the point dose, and the dose distribution are major issues in the RTP related QA procedure. The leaf sequence file generation, the evaluation of the MLC control file, the comparison of the dry run film, and the IMRT field simulate image were included in the treatment information flow procedure QA. The patient setup QA, the verification of the IMRT treatment fields to the patients, and the examination of the data in the Record & Verify system make up the treatment delivery QA procedure. Results : The point dose measurement results of 10 cases showed good agreement with the RTP calculation within $3\%$. One case showed more than a $3\%$ difference and the other case showed more than $5\%$, which was out side the tolerance level. We could not find any differences of more than 2 mm between the RTP leaf sequence and the dry run film. Film dosimetry and the dose distribution from the phantom plan showed the same tendency, but quantitative analysis was not possible because of the film dosimetry nature. No error had been found from the MLC control file and one mis-registration case was found before treatment. Conclusion : This study shows the usefulness and the necessity of the IMRT patient QA program. The whole procedure of this program should be peformed, especially by institutions that have just started to accumulate experience. But, the program is too complex and time consuming. Therefore, we propose practical and essential QA items for institutions in which the IMRT is performed as a routine procedure.

Perceptions and Opinions about Male Breast Cancer and Male Breast Self-Examination: A Qualitative Study

  • Al-Naggar, Redhwan Ahmed;Al-Naggar, Dhekra Hamoud
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.1
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    • pp.243-246
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    • 2012
  • Objective: While the relatively common nature of female breast cancer has resulted in a high level of general awareness, male breast cancer is still comparatively unknown to the general public and to healthcare professionals. The objective of this study is to explore the perceptions and opinions about male breast cancer and male breast self-examination among male university students. Methodology: In-depth interviews were conducted among 36 male university students from the Management and Science University, Malaysia, selected by simple random sampling. The themes of the interview were: knowledge of male breast cancer and male breast self-examination, sources of knowledge and attitudes towards male BSE. The data obtained were classified into various categories and analyzed manually. Results: The majority of participants mentioned that there is a low possibility for males to get breast cancer. They also believed that the cause of breast cancer among men is due to the carcinogens from cigarettes. The majority of participants mentioned that they know about breast self-examination from the mass media and that the presence of a lump in the breast is the main symptom of breast cancer in men. The majority of participants mentioned that they encourage their family members to practice breast self-examination but considered that BSE is not important for men because they have a low probability of getting breast cancer. Conclusions: Misconceptions regarding male breast cancer and breast self-examination among men still exist among male university students. Therefore especial attention should be given to educate men about male breast cancer and male BSE.

A Study On the Theory of 'Pungent and Sweet becoming Yang' and 'Sour and Sweet becoming Yin' (신감화양(辛甘化陽), 산감화음(酸甘化陰)의 이론에 대한 고찰)

  • Yun, Ki-ryoung
    • Journal of Korean Medical classics
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    • v.35 no.2
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    • pp.33-49
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    • 2022
  • Objectives : This paper aims to investigate the role of the sweet flavor within the contexts of 'pungent and sweet becoming Yang' and 'sour and sweet becoming Yin' and the meaning of the two concepts. Methods : Related contents in databases including the Siqu Quanshu were searched with 'pungent and sweet becoming Yang' and 'sour and sweet becoming Yin', whose understanding and application were examined. Results & Conclusions : The theories of 'pungent and sweet becoming Yang' and 'sour and sweet becoming Yin' originate from Cheng Wuji's comparison of the Gancaoqianjiangtang and Shaoyaogancaotang in the 29th verse of the Shanghanlun. The two terms first appeared in the Qing period among the Wenbing school. In other medical texts, the combination with sweet flavors could be found with salty, bitter and bland flavors other than with pungent and sour. The role of the sweet flavor in 'pungent and sweet becoming Yang' and 'sour and sweet becoming Yin' is to accomplish the dispersing and converging action slowly and effectively, by supplying energy in small amounts preventing it from happening too quickly, corresponding to its Earth nature of the Five Elements which harmonizes the Yin and Yang. While 'becoming Yin' and 'becoming Yang' could be understood as tonifying Yin and Yang, it could also be understood as 'doing Yin' and 'doing Yang', The specific actions differ according to herb and mixture. The point of distinction between the aforementioned tonification and that of medicinals that have Yin and Yang tonifying properties is that due to the other flavor that is matched with the sweet flavor, Qi is given motility which allows for tonification without stagnation.

Effectiveness of Electroacupuncture for Managing Urinary Retention Post Lumbar Spine Surgery: a retrospective single-cohort study

  • Phuong Dong Tran;Quoc Dung Nguyen;Thanh Duc Ngo
    • Journal of Pharmacopuncture
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    • v.27 no.2
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    • pp.123-130
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    • 2024
  • Objectives: Post-operative urinary retention (POUR) is a frequent complication following surgical procedures, characterized by an acute inability to void, leading to additional complications and extended hospitalization. Acupuncture has been shown to be effective in facilitating spontaneous urination and alleviating anxiety in patients experiencing poor urination. The present study aims to evaluate the effectiveness of electroacupuncture in the management of POUR in patients who have undergone lumbar spine surgery. Methods: This retrospective study conducted at the National Hospital of Acupuncture in Vietnam and reviewed the medical records of patients over 18 years old who underwent lumbar spine surgery and were diagnosed with POUR between January to December 2019. Electroacupuncture was administered at five specific acupuncture points: Qugu (CV2), Zhongji (CV3), Zhibian (BL54), Pangguanshu (BL28), and Kunlun (BL60). This study monitored key parameters related to the effectiveness of the acupuncture treatment, including the number of acupuncture treatment sessions required until a patient was successfully treated was recorded, with a maximum of three acupuncture treatment sessions per patient, the time elapsed until urination following the treatment (minutes), and urinary bladder volume before and after treatment (mL). Results: The study demonstrated a 93.3% success rate in treating POUR with electroacupuncture. A significant reduction in post-void residual volume was noted, and patients could void within 30 minutes post-treatment. No significant differences in treatment effectiveness were observed across difference genders and age groups. Conclusion: Electroacupuncture proved to be a highly effective treatment for POUR in patients post-lumbar spine surgery, with a rapid response time and substantial reduction in PVR. However, the retrospective nature of the study and single-center focus limit its generalizability. Future research incorporating randomized controlled trials or multi-center observational studies are recommended to validate these findings and explore the potential of acupuncture in POUR management on a broader scale.