• 생물환경조절학회지
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• 제29권1호
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• pp.9-19
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• 2020

대류열전달은 겨울철 온실 열손실의 중요한 원인이 되며, 일반적으로 복사열에 의한 손실보다 더 크다. 스크린의 대류열전달계수를 자연상태에서 측정한 연구가 수행된 바는 있지만 상하면의 재질이 동일하고 공극이 없는 스크린에 대해서는 적용을 할 수 없는 방법이다. 이러한 재질의 스크린은 한국에서 많이 사용되고 있으나 대류열전달 특성을 파악하는데 많은 어려움이 있는 실정이다. 본 연구에서는 공극이 없는 3가지 종류의 스크린에 대해 대류열전달계수를 구하였으며, 계수를 산정하기 위하여 복사열수지 이론에 근거하여 산정방법을 개발하였다. 실험장치에 스크린을 설치하고 일사량, 장파복사량, 대기온도, 스크린 및 흑색천의 표면온도, 풍속 등을 측정하였다. 스크린의 표면온도와 주변온도의 차이에 따른 대류열전달계수를 산정하였다. 풍속이 거의 없는 상태에서 온도의 차이가 증가함에 따라 계수는 감소하는 것으로 나타났다.

• 방사성폐기물학회지
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• 제13권1호
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• pp.73-86
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• 2015

방사성폐기물 처분시설을 보유하고 있는 국가들은 방사성폐기물 처분시설 시스템의 이해도 제고 및 신뢰성 증진을 위해서는 다양한 보조지표를 선정하여 평가하고 있다. 본 논문에서는 처분시설에 적용되는 국외 처분시설의 보조지표들을 조사하고, 우리나라 월성 중·저준위 방사성폐기물 처분시설에서 근계지역의 공학적 방벽과 원계지역의 자연방벽 성능평가를 위해 연속적인 방벽에서의 방사성 핵종 이동을 보여줄 수 있는 방벽 간의 방사성 핵종 플럭스를 보조안전지표로 선정하여 적용하였다. 처분시설의 정상시나리오를 콘크리트 사일로의 건전조건과 열화조건으로 나누어 방벽별 성능평가를 수행하였으며, 방사성 핵종에서 방벽별 지연성능 기여도를 확인하였다. 콘크리트가 건전한 경우에서 공학적 방벽의 방벽별 상세성능을 파악하였으며, 열화콘크리트의 경우, 공학적 방벽의 성능저하도 및 자연암반과의 상대적 중요도를 정량적으로 확인하였다. 향후본 연구 결과는 2단계 표층처분시설 설계 최적화 및 방벽성능의 검증방법으로 활용할 수 있다. 아울러, 향후에는 처분시설의 Safety Case 구축과 안전성의 이해 제고 및 신뢰성 증진을 위하여 지속적으로 보조지표를 추가 선정하여 평가하고자 한다.

• 대한환경공학회지
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• 제34권12호
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• pp.801-809
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• 2012

본 연구에서는 장기간 동안 양수리 용늪에서의 총 수은(TM)과 용존가스상 수은(DGM; $Hg^0$) 농도를 측정하였다. 평균 TM 및 DGM의 농도는 각각 $2.0{\pm}2.0$ ng/L와 $15.0{\pm}2.8$ pg/L로 나타나, TM의 약 2.6%만이 DGM의 형태로 존재하였다. 연구기간동안 TM 농도는 뚜렷한 계절적 변이를 보이지 않았으나 DGM 농도는 여름철에 통계적으로 유의하게 높은 농도가 나타났다. 이는, DGM이 강한 태양광과 높은 수온에 의해서 효과적으로 생성된다는 것을 의미한다. 또한 양수리 용늪에서 측정한 TM과 DGM 농도 사이에는 유의한 상관관계가 관측되지 않았다. 양수리 용늪에서 측정한 DGM은 대부분의 연구 기간 동안 과포화 상태로 존재하였으며, 이는 수표면의 $Hg^0$가 대기로 쉽게 휘발될 수 있다는 사실을 나타낸다.

• 대한화장품학회:학술대회논문집
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• 대한화장품학회 2003년도 IFSCC Conference Proceeding Book I
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• pp.780-803
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• 2003

Exposure of skin cells, particularly keratinocytes to various nuclear factor-kappaB ($\textrm{NF}_{-{\kappa}}\textrm{B}$) activators [e.g. tumor necrosis factor-$\alpha$, interleukin-1, lipopolysaccharides, and ultraviolet light] leads to phosphorylation and degradation of the inhibitory protein, $\textrm{I}_{{\kappa}}\textrm{B}$. Liberated $\textrm{NF}_{-{\kappa}}\textrm{B}$ is translocated into the nucleus where it can change or alter expression of target genes, resulting in the secretion of extracellular signaling molecules including melanotrophic factors affecting melanocyte. In order to demonstrate the possible role of $\textrm{NF}_{-{\kappa}}\textrm{B}$ activation on the synthesis of melanotrophic factors from the keratinocytes, the activities of $\textrm{NF}_{-{\kappa}}\textrm{B}$ induced by melanogenic inhibitors (MIs) were determined in human HaCaT keratinocytes transfected with $\textrm{pNF}_{-{\kappa}}\textrm{B}$-SEAP-NPT plasmid. Transfectant cells released the secretory alkaline phosphatase (SEAP) as a transcription reporter in response to the $\textrm{NF}_{-{\kappa}}\textrm{B}$ activity and contain the neomycin phosphotransferase (NPT) gene for the dominant selection marker for geneticin resistance. MIs such as niacinamide, kojic acid, hydroquinone, resorcinol, arbutin, and glycolic acid were preincubated with transfectant HaCaT cells for 3 h and then ultraviolet B (UVB) was irradiated. $\textrm{NF}_{-{\kappa}}\textrm{B}$ activation was measured with the SEAP reporter gene assay using a fluorescence detection method. Of the Mis tested, kojic acid ($IC_{50}$/ = 60 $\mu$M) was found to be the most potent inhibitor of UVB-upregulating $\textrm{NF}_{-{\kappa}}\textrm{B}$ activation in transfectant HaCaT cells, which is followed by niacinamide ($IC_{50}$/= 540 $\mu$M). Pretreatment of the transfectant HaCaT cells with the Mis, especially kojic acid and niacinamide, effectively lowered $\textrm{NF}_{-{\kappa}}\textrm{B}$ binding measured by electrophoretic mobility shift assay. Furthermore, these two inhibitors remarkably reduced the secretion level of IL-6, one of melanotrophic factors, triggered by UV-radiation of the HaCaT cells. These observations suggest that Mis working at the in vivo level might act partially through the modulation of the synthesis of melanotrophic factors in keratinocyte.

• 한국재료학회:학술대회논문집
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• 한국재료학회 2011년도 춘계학술발표대회
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• pp.15-15
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• 2011

As you know, boron compounds, borax ($Na_2B_4O_5(OH)_4{\cdot}8H_2O$) etc. were known thousands of years ago. As for natural boron, it has two naturally occurring and stable isotopes, boron 11 ($^{11}B$) and boron 10 ($^{10}B$). The neutron absorption $^{10}B$ is included about 19~20% with 80~81% $^{11}B$. Boron is similar to carbon in its capability to form stable covalently bonded molecular networks. The mass difference results in a wide range of ${\beta}$ values between the $^{11}B$ and $^{10}B$. The $^{10}B$ isotope, stable with 5 neutrons is excellent at capturing thermal neutrons. For example, it is possible to decrease a thermal neutron required for the nuclear reaction of uranium 235 ($^{235}U$). If $^{10}B$ absorbs a neutron ($^1n$), it will change to $^7Li+^1{\alpha}$ (${\alpha}$ ray, like $^4He$) with prompt ${\gamma}$ ray from $^{11}B$ $^{11}B$ (equation 1). $$^{10}B+^1n\;{\rightarrow}\;^{11}B\;{\rightarrow}\; prompt \;{\gamma}\;ray (478 keV), \;^7Li+4{\alpha}\;(4He)\;\;\;\;{\cdots}\; (1)$$ If about 1% boron is added to stainless steel, it is known that a neutron shielding effect will be 3 times the boron free steel. Enriched boron or $^{10}B$ is used in both radiation shielding and in boron neutron capture therapy. Then, $^{10}B$ is used for reactivity control and in emergency shutdown systems in nuclear reactors. Furthermore, boron carbide, $B_4C$, is used as the charge of a nuclear fission reaction control rod material and neutron cover material for nuclear reactors. The $B_4C$ powder of natural B composition is used as a charge of a control material of a boiling water reactor (BWR) which occupies commercial power reactors in nuclear power generation. The $B_4C$ sintered body which adjusted $^{10}B$ concentration is used as a charge of a control material of the fast breeder reactor (FBR) currently developed aiming at establishment of a nuclear fuel cycle. In this study for new boron compound, silicon boride ceramics for capturing thermal neutrons, preparation and characterization of both silicon tetraboride ($SiB_4$) and silicon hexaboride ($SiB_6$) and ceramics produced by sintering were investigated in order to determine the suitability of this material for nuclear power generation. The relative density increased with increasing sintering temperature. With a sintering temperature of 1,923 K, a sintered body having a relative density of more than 99% was obtained. The Vickers hardness increased with increasing sintering temperature. The best result was a Vickers hardness of 28 GPa for the $SiB_6$ sintered at 1,923K for 1 h. The high temperature Vickers hardness of the $SiB_6$ sintered body changed from 28 to 12 GPa in the temperature range of room temperature to 1,273 K. The thermal conductivity of the SiB6 sintered body changed from 9.1 to 2.4 W/mK in the range of room temperature to 1,273 K.

• Asian Pacific Journal of Cancer Prevention
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• 제17권1호
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• pp.65-71
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• 2016

Although high mammographic density is one of the strongest predictors of breast cancer risk, X-ray based mammography cannot be performed before the recommended screening age, especially not in adolescents and young women. Therefore, new techniques for breast density measurement are of interest. In this pilot study in Guam and Hawaii, we evaluated a radiation-free, bioimpedance device called Electrical Breast Densitometer$^{TM}$ (EBD; senoSENSE Medical Systems, Inc., Ontario, Canada) for measuring breast density in 95 women aged 31-82 years and 41 girls aged 8-18 years. Percent density (PD) was estimated in the women's most recent mammogram using a computer-assisted method. Correlation coefficients and linear regression were applied for statistical analysis. In adult women, mean EBD and PD values of the left and right breasts were $230{\pm}52$ and $226{\pm}50{\Omega}$ and $23.7{\pm}15.1$ and $24.2{\pm}15.2%$, respectively. The EBD measurements were inversely correlated with PD ($r_{Spearman}=-0.52$, p<0.0001); the correlation was stronger in Caucasians ($r_{Spearman}=-0.70$, p<0.0001) than Asians ($r_{Spearman}=-0.54$, p<0.01) and Native Hawaiian/Chamorro/Pacific Islanders ($r_{Spearman}=-0.34$, p=0.06). Using 4 categories of PD (<10, 10-25, 26-50, 51-75%), the respective mean EBD values were $256{\pm}32$, $249{\pm}41$, $202{\pm}46$, and $178{\pm}43{\Omega}$ (p<0.0001). In girls, the mean EBD values in the left and right breast were $148{\pm}40$ and $155{\pm}54{\Omega}$; EBD values decreased from Tanner stages 1 to 4 ($204{\pm}14$, $154{\pm}79$, $136{\pm}43$, and $119{\pm}16{\Omega}$ for stages 1-4, respectively) but were higher at Tanner stage 5 ($165{\pm}30{\Omega}$). With further development, this bioimpedance method may allow for investigations of breast development among adolescent, as well as assessment of breast cancer risk early in life and in populations without access to mammography.

• 한국조경학회지
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• 제36권1호
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• pp.80-89
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• 2008

Generally, trees lining the streets are the most easily accessible green areas in the city and constitute the smallest basic unit in the formation of the urban linear green axis. This study attempts to interpret issues related to city trees from a comprehensive and relational viewpoint. The site of this study is Central Park Street in front of Incheon Metropolitan City Hall. This street is representative of those in Incheon City. This study is an inter-relational interpretation of issues by measuring the vitality of these trees. The following are results of this study: First, the vitality of city trees is higher in those trees growing in natural ground than those growing in plant gratings. This observation can lead to budget savings and increased natural areas in the city. Also, if planter and multi-layering planting methods are introduced where damage to trees is predicted, variation to urban landscape can be achieved while linking to reinforced rearing foundation of street-side trees. Second, there is need for a holistic approach to caring for street-side trees regarding the damage caused by drastic pruning and strong street lights. The typical functions of these trees, like supplying freshness in summer, absorbing solar radiation, and controlling the urban micro-climate are closely related to the vitality of the trees. Accordingly, the function and ecology should be understood holistically, not separately. In this aspect, the functional and ecological use of the multi-layering planting method is effective in protecting pedestrians from vehicles as well. Third, the fallen leaves of monotonous rows of trees have different ecological and functional effects. Not only is the index of greenness in the urban setting increased, but there are also aesthetic and symbolic effects. Fourth, in spite of being the street along which Incheon Metropolitan City Hall, major administrative buildings and Central Park are located, this street does not have its own special identity to discriminate it from other streets. It fulfills only functional criteria based on uniformity. If there is no paradigm shift from today's street system based on vehicles, the role of landscape architecture will be very passive in regards to street-side trees, the minimum unit of urban green. Fifth, on this particular street, many trees were planted in December, which reflects a deficiency of short and long-term strategy, like a street-tree master plan. In this aspect, we still lack a mature culture concerning these trees as a basic unit in urban greenery. Furthermore, there needs to be cultural introspection concerning present administrative practices.

• Advances in Traditional Medicine
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• 제6권1호
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• pp.12-20
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• 2006

Some natural products are able to inhibit radiation effects and exert an antitumor effect with fewer adverse reactions; however, their antitumor effects are less than those of widely-used synthetic drugs. Propolis is a natural material that has been attracting attention, and we extracted this material with water and investigated the effect of continuous propolis administration on radioactivity-induced reduction of hemocytes, in addition to the antioxidant and antitumor effects of propolis. Following a 1-week adjustment period, water-soluble propolis was administered intraperitoneally to male ICR mice at a dose of 100 mg/kg every other day for 2 weeks. Following administration, 2 Gy whole-body irradiation was performed and the counts of leukocytes, lymphocytes, and granulocytes and monocytes in the peripheral blood were determined 1, 3, 7, 15 and 30 days after irradiation. These cells were considered since they are closely associated with immunity to radioactivity. In a second experiment, water-soluble propolis was similarly administered to the mice for 2 weeks after a 1-week adjustment period, and 2 Gy whole-body irradiation was performed. The antioxidant effects in hemocytes were then investigated using 2,2'-azobis (2-amidinopropane) dihydrochloride (AAPH), a radical generator. In a third experiment, $1\;{\times}\;10^6$ Sarcoma-180 cells were inoculated into the right thigh of mice, which were divided into four groups: control, water-soluble propolis-treated, 6 Gy irradiated and water-soluble propolis-treated + 6 Gy irradiated groups, and changes in tumor size were measured for 20 days. Statistical analysis was conducted using ANOVA for multiple groups. In the three experiments, administration of water-soluble propolis inhibited the reduction of hemocytes caused by whole-body irradiation, showed antioxidant effects against radioactivity, and inhibited tumor growth, respectively. In conclusion, our data suggest that the antioxidant effect of watersoluble propolis inhibits hemocyte reduction caused by whole-body irradiation and enhances immunological inhibition of tumor growth.

• 한국환경보건학회지
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• 제45권6호
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• pp.668-674
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• 2019

Objectives: Modern people spend most of their day indoors. As the health impact of radon becomes an issue, public interest also has been growing. The primary route of potential human exposure to radon is inhalation. Long-term exposure to high levels of radon increases the risk of developing lung cancer. Radon exposure is known to be the second-leading cause of lung cancer, following tobacco smoke. This study measures the indoor radon concentrations in detached houses in area A of Chungcheongbuk-do Province considering the construction year, cracks in the houses, the location of installed detectors, and seasonal effects. Methods: The survey was conducted from September 2017 to April 2018 on 1,872 private households located in selected areas in northern Chungcheongbuk-do Province to figure out the year of building construction and the location of detector installed and identify the factors which affect radon concentrations in the air within the building. Radon was measured using a manual alpha track detector (Raduet, Hungary) with a sampling period of longer than 90 days. Results: Indoor radon concentrations in winter within area A was surveyed to be 168.3±193.3 Bq/㎥. There was more than a 2.3 times difference between buildings built before 1979 and those built after 2010. The concentration reached 195.4±221.9 Bq/㎥ for buildings with fractures and 167.2±192.4 Bq/㎥ for buildings without fractures. It was found that detectors installed in household areas with windows exhibited a lower concentration than those installed in concealed spaces. Conclusion: High concentrations of indoor radon were shown when there was a crack in the house. Also, ventilation seems to significantly affect radon concentrations because when the location of the detector in the installed site was near windows compared to an enclosed area, radon concentration variation increased. Therefore, it is considered that radon concentration is lower in summer because natural ventilation occurs more often than in winter.

• 한국수자원학회논문집
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• 제38권8호
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• pp.617-629
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• 2005

본 논문은 비단조적으로 변동하는 시계열자료를 단조적으로 변화하는 구간으로 분할하여 경향성을 분석함으로써 자료의 시변동에 대한 동질성을 향상시키고 그에 따라 경향성 분석기법의 탐지력을 향상시킬 수 있다는 가설을 전제로 하고 있다. 이를 검토하기 위한 기법으로서 시계열자료의 변동경향을 파악하기 위한 필터링 방법으로 LOWESS smoothing을 적용하였고, 시계열자료의 경향성분석은 seasonal Kendall test를 적용하였다. 인위적으로 발생시킨 시계열자료와 대청호의 수온, 유량, 기온, 일사량 등의 시계열자료를 대상으로 검토한 결과 비단조적인 변화를 보이는 시계열자료를 단조적인 변화구간으로 분할하여 경향성을 분석함으로써 자료의 변동 경향성과 기울기 판정의 정확도를 높일 수 있었다. 그리고, 자료의 시변동에 대한 동질성 향상은 계절 변동성의 동질성에 대한 변화를 보다 정확하게 분석하는데 도움을 주는 것으로 보였으며 이것은 자연현상에 대한 인간활동의 영향을 고찰할 수 있는 자료로서 앞으로 이에 대한 연구가 더 필요할 것으로 보인다. 본 논문에서 제시한 방법은 시계열자료의 단조적인 경향성을 분석하는 기법들에 대해 적용 가능하며, 이를 통하여 환경변화의 경향성에 대한 보다 정확한 분석과 판단이 가능해질 것으로 기대한다.