• Title/Summary/Keyword: Natural

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Acronyculatin P, A New Isoprenylated Acetophenone from the Stem Bark of Acronychia pedunculata

  • Tanjung, Mulyadi;Nurmalasari, Intan;Wilujeng, Aisyah Kanti;Saputri, Ratih Dewi;Rachmadiarti, Fida;Tjahjandarie, Tjitjik Srie
    • Natural Product Sciences
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    • v.24 no.4
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    • pp.284-287
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    • 2018
  • A new isoprenylated acetophenone, acronyculatin P (1) as well as two known compounds, 3',5'-diisoprenyl-2',4'-dihydroxy-6'-methoxyphenylethanone (2) and 3'-isoprenyl-2',4',6'-trihydroxyphenylethanone (3) were isolated from the stem bark of Acronychia pedunculata (L.) Miq. The structures were determined by HRESIMS, 1D and 2D NMR. The inhibitory activity of the isoprenylated acetophenone derivatives against murine leukemia P-388 cells showed compound 1 moderate activity with $IC_{50}$ $15.42{\mu}M$.

An Analysis on the Naturalness of Natural Logarithm and its Educational Implication (자연로그의 자연스러움에 대한 분석과 그에 따른 교육적 시사점)

  • Park, Sun-Yong
    • Journal for History of Mathematics
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    • v.32 no.3
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    • pp.109-134
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    • 2019
  • In order to improve the educational situation in which the natural number e and the natural logarithm are dealt with somewhat perfunctorily, this study explores the genetic process in which the natural logarithm and its base e occurred, and has an educational discussion based on that analysed process. Specifically, the study inquires into how the natural logarithm happened in relation to the quadrature of the hyperbolic curves through analysis and thought experimentation in mathematics history. Particularly, it sheds light on the role of e and the naturalness of the natural logarithm in terms of the introduction of the real number exponent. Also, this study discusses what the findings suggest educationally.

Chemical Constituents Isolated from the Moss-derived Fungus Talaromyces sp.

  • Hwang, Hoseong;Kwon, Hak Cheol;Kwon, Jaeyoung
    • Journal of the Korean Magnetic Resonance Society
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    • v.24 no.4
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    • pp.123-128
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    • 2020
  • All plants in natural ecosystems are living in symbiosis with endophytes. Recently, there has been an increasing interest in endophytes since these organisms can interact with the hosts and produce various structurally or biologically interesting molecules. This study aimed to identify these molecules from endophytes. Chemical investigation of Climacium dendroides-derived fungus Talaromyces sp. resulted in the isolation of two diphenyl ether derivatives, purpactin A (1) and penicillide (2), and two steroids, dankasterone A (3) and calvasterol B (4). The structures of the compounds were identified via extensive spectroscopic and spectrometric methods. Four compounds did not show any antioxidative activities in the on-line antioxidant activity screening system.

Preventive Agents against Sepsis and New Phenylpropanoid Glucosides from the Fruits of Illicium verum

  • Lee, Sung-Won;Li, Gao;Lee, Kyong-Sun;Jung, Jun-Sub;Xu, Ming-Lu;Seo, Chang-Seob;Song, Dong-Keun;Son, Jong-Keun
    • Proceedings of the PSK Conference
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    • 2003.04a
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    • pp.257.1-257.1
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    • 2003
  • The bioassay-guided fractionation of preventive agents against lethality due to septic shock from the fruits of Illicium verum lead to the isolation of two known racemic mixtures of phenylpropanoids (1 and 2), along with two known phenylpropanoid glucosides (3 and 5) and two new phenylpropanoid glucosides (4 and 6). Their chemical structures were elucidated on the basis of spectroscopic studies. (omitted)

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