• 한국수산과학회지
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• 제36권2호
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• pp.113-119
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• 2003

A feeding trial was carried out to Investigate the effect of lipid level and herb mixture in the diets on growth of juvenile parrot fish, Oplegnathus fasciatus. Two plicate groups of fish averaging 4.5 g were fed four experimental diets containing herb mixture (0 and 5 g/kg diet) at each of two lipid levels $(8\%\;and\;16\%)$ for 8 months from summer to spring (water temperature, $7.2-25.4^{\circ}C)$. Weight gain improved with increasing dietary lipid level or supplementation of herb mixture during the first 4 months feeding period. Weight gain of fish fed the diet containing $16\%$ lipid level was significantly higher (P<0.05) than that of fish fed the diet containing $8\%$ lipid level. Weight gain of fish fed the diet with herb mixture was significantly higher (P<0.05) than that of fish fed the diet without herb at the $16\%$ lipid level. Feed efficiency was influenced by dietary lipid level or herb mixture during the first 4 months. On the other hand, weight gain and feed efficiency were not affected by dietary lipid level and herb mixture after 4 months until end of feeing period. Survival of fish fed the diet containing $8\%$ lipid without supplementation of herb mixture was the lowest among the groups (P<0.05). Lipid contents of liver and viscera tended to increase with increasing dietary lipid level during the first 4 months feeding period, however muscle lipid content was not influenced by dietary lipid and herb. Total cholesterol of serum was influenced by dietary lipid level during the first 4 months feeding period. These results indicate that an increase of dietary lipid level from $8\%\;to\;16\%$ and supplementation of herb mixture can improve growth performance of juvenile parrot fish when water temperature is optimum for growth such as the summer season in Korea.

• 한국지형학회지
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• 제20권1호
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• pp.85-96
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• 2013

본 연구는 국립공원관리공단에서 시행한 국립공원 2 3기 자연자원조사 자료와 국립환경과학원 2 3차 전국자연환경조사 자료를 수집하여 공원별 지형경관자원을 유형별로 재분류하였다. 연구결과, 수집된 전체 국립공원 내 지형경관자원 수는 총 3,169개였다. 전체 경관자원 중 I등급으로 판정된 경관자원은 794개로 약 36.9%를 차지하였다. 다음으로, II등급으로 판정된 경관자원이 546개로 약 25.3%, III등급으로 판정된 경관자원이 459개로 약 21.3%, 마지막으로 보전등급이 낮은 IV등급으로 판정된 경관자원이 191개로 약 8.9%를 차지하고 있는 것으로 분석되었다. 국립공원별 I등급 경관자원 수는 설악산 207개소, 다도해해상 92개소, 지리산 84개소, 태안해안 60개소 순이었으며, 다도해해상국립공원과 설악산국립공원, 태안해안국립공원, 지리산국립공원, 속리산국립공원, 계룡산국립공원 등이 지형경관자원이 우수한 국립공원으로 평가되었다. 이러한 우수한 경관자원을 활용하기 위해서는 국립공원 탐방객에게 경관자원에 대한 이해와 관심을 높이고 탐방객의 만족도를 높이기 위한 조망지점이 필요하다. 이를 위해서는 우수경관 조망점 지도를 작성하여 탐방로 입구 혹은 일정지점에 설치하여 탐방객들에게 지형경관자원에 대한 유용한 정보를 제공해야 할 것으로 판단된다.

• 문화기술의 융합
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• 제8권4호
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• pp.83-89
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• 2022

본 연구는 은행 대출이 주택가격에 미치는 영향을 분석하였으며, 은행 대출을 은행 총대출금, 가계대출금, 부동산담보대출금으로 구분하였고, 주택가격을 전국, 지방, 서울 주택가격으로 구분하여 분석하였다. 주요한 분석 결과는 다음과 같다. 첫째, 은행 총대출금의 증가는 전국, 지방, 서울 주택가격을 유의하게 상승시키는 것으로 나타났다. 둘째, 가계대출금은 지방 주택가격에 양(+)의 영향을 미치지만 통계적으로 유의하지는 않은 것으로 나타났다. 그리고 은행 대출이 지방 주택가격에 미치는 영향은 전국 주택가격에 미치는 영향에 비해서는 상대적으로 작은 것으로 나타났다. 셋째, 은행 대출이 지방 주택가격과 서울 주택가격에 미치는 영향은 차이가 있는 것으로 나타났다. 넷째, 인플레이션과 은행 총대출은 1분기의 시차를 가지고 지방 주택가격에 유의한 양(+)의 영향을 미쳤으며, 단기금리는 1분기의 시차를 가지고 서울 주택가격에 유의한 음(-)의 영향을 미쳤다. 전체적으로는 은행 대출이 주택가격에 미치는 영향이 지방보다는 서울에 약 2배 정도 더 큰 양(+)의 영향을 미치는 것으로 나타났다.

• 대한의생명과학회지
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• 제14권1호
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• pp.13-18
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• 2008

Excessive alcohol consumption is associated with increased risks of many diseases including cancer. Individuals who regularly consume excessive quantities of alcohol have a greater risk of developing head and neck cancers such as esophageal, pharyngeal and oral cavity cancers if they are deficient in ALDH2 expression compared to normal populations. We evaluated lipid peroxidation in Aldh2 +/+ and Aldh2 -/- mice after they had been subjected to acute ethanol exposure. Malondialdehyde(MDA) level in liver tissue was evaluated as a biomarker of oxidative lipid peroxidation. Although the ethanol treatment did not increase the hepatic MDA level both in Aldh2 +/+ mice and in Aldh2 -/- mice, the MDA level was significant higher in the Aldh2 -/- mice than in the Aldh2 +/+ group. The MDA level was also significantly correlated with olive tail moment in blood and the level of 8-OHdG in liver tissue. This is a strong evidence to support our hypothesis that oxidative stress is more intense in Aldh2 -/- mice than in Aldh2 +/+ mice. Our results suggest that ALDH2-deficient individuals may be more susceptible than wild-type ALDH2 individuals to ethanol-mediated liver disease, including cancer.

• Journal of Preventive Medicine and Public Health
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• 제45권2호
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• pp.90-97
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• 2012

Objectives: While there have been many quantitative studies on the public's attitude towards mental illnesses, it is hard to find quantitative study which focused on the contextual effect on the public's attitude. The purpose of this study was to identify factors that affect the public's beliefs and attitudes including contextual effects. Methods: We analyzed survey on the public's beliefs and attitudes towards mental illness in Korea with multi-level analysis. We analyzed the public's beliefs and attitudes in terms of prejudice as an intermediate outcome and social distance as a final outcome. Then, we focused on the associations of factors, which were individual and regional socioeconomic factors, familiarity, and knowledge based on the comparison of the intermediate and final outcomes. Results: Prejudice was not explained by regional variables but was only correlated with individual factors. Prejudice increased with age and decreased by high education level. However, social distance controlling for prejudice increased in females, in people with a high education level, and in regions with a high education level and a high proportion of the old. Therefore, social distance without controlling for prejudice increased in females, in the elderly, in highly educated people, and in regions with a high education and aged community. Conclusions: The result of the multi-level analysis for the regional variables suggests that social distance for mental illness are not only determined by individual factors but also influenced by the surroundings so that it could be tackled sufficiently with appropriate considering of the relevant regional context with individual characteristics.

• Journal of Korean Neurosurgical Society
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• 제54권6호
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• pp.496-500
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• 2013

Objective : To evaluate the successful fusion rate in postmenopausal women with single-level anterior cervical discectomy and successful fusion (ACDF) and identify the significant factors related to bone successful fusion in pre- and postmenopausal women. Methods : From July 2004 to December 2010, 108 consecutive patients who underwent single-level ACDF were prospectively selected as candidates. Among these, the charts and radiological data of 39 women were reviewed retrospectively. These 39 women were divided into two groups : a premenopausal group (n=11) and a postmenopausal group (n=28). To evaluate the significant factors affecting the successful fusion rate, the following were analyzed : the presence of successful fusion, successful fusion type, age, operated level, bone mineral density, graft materials, stand-alone cage or plating with autologous iliac bone, subsidence, adjacent segment degeneration, smoking, diabetes mellitus, and renal disease. Results : The successful fusion rates of the pre- and postmenopausal groups were 90.9% and 89.2%, respectively. There was no significant difference in the successful fusion rate or successful fusion type between the two groups. In the postmenopausal group, three patients (10.8%) had successful fusion failure. In the postmenopausal group, age and subsidence significantly affected the successful fusion rate (p=0.016 and 0.011, respectively), and the incidence of subsidence in patients with a cage was higher than that in patients with a plate (p=0.030). Conclusion : Menopausal status did not significantly affect bone successful fusion in patients with single-level ACDF. However, in older women with single-level ACDF, the combination of use of a cage and subsidence may unfavorably affect successful fusion.

• 대한치과보철학회지
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• 제44권1호
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• pp.63-72
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• 2006

Purpose: The purpose of this study was to compare the accuracy of master cast fabricated by using different impression methods at the different impression levels. Material and Method: The master model used in this study was resin block having low implant analogs. Impression method studied were 1) direct method on future level (Group FIX-D), 2) Indirect method on fixture level(Group FIX-I), 3) Modified indirect method on fixture level(Group FD(-M), 4) Direct method on abutment level(Group AB-D) and 5) Indirect method on abutment level(Group AB-I). Each of the five groups took 10 impressions. Fifty impressions were made for master cast by using Impregum $F^(R)$ impression material loaded on individual tray. Three dimensional measuring microscope was used to measure the inter-implant distance. Error rate of each inter-implant distance were calculated and evaluated. Results: The results were as follows. 1. Group FIX exhibited higher accuracy than group AB. 2 In group FIX, modified indirect method showed the highest accuracy, while indirect method showed the lowest accuracy. In group Ab, indirect method showed the higher accuracy than direct method. 3. Group FIX showed larger horizontal error than group AB. But, group AB showed the larger vertical error than group FIX. 4. Group Fix-M showed smallest vertical and horizontal error.

• 한국임상약학회지
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• 제31권3호
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• pp.237-246
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• 2021

Background: Pembrolizumab, an anti-cancer drug, is known to increase the activity of the immune system, leading to side effects called immune-related adverse events (irAE), including type 1 diabetes. This study analyzed the correlation between blood glucose level and pembrolizumab administration and investigated the covariates that affect those changes in cancer treatment. Methods: The information of 133 adult cancer patients was obtained from the electronic medical record (EMR) to identify the changes in random blood glucose (RBG) levels during the pembrolizumab treatment. Subjects were classified into subgroups according to their baseline RBG level, history of diabetes, and the use of steroids, and linear regression analysis was conducted. In addition, a secondary analysis was performed within the group of subjects having a strong correlation to glycemic change, which was based on the Pearson correlation coefficient being less than -0.7 or greater than +0.7. Univariate and multivariate logistic regressions were conducted to identify the risk factors to glycemic increase. Results: The RBG level tended to descend without significant differences in total patients during the administration period of pembrolizumab. Despite the insignificance, the logistic regression analysis presents that the odds ratios of baseline RBG less than 130 mg/dL, prophylactic steroid use, and higher dose of pembrolizumab per cycle (mg/kg/cycle) were greater than 1. Conclusions: Prophylactic administration of steroids and a higher dose of pembrolizumab per cycle may increase the blood glucose level as irAE in cancer patients with a strong tendency to glycemic change.

• 한국해안·해양공학회논문집
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• 제28권1호
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• pp.34-43
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• 2016

국내의 연안은 지속적 발전으로 해수면 상승(sea level rise, SLR)으로 인한 연안재해 취약성이 가중될 것으로 전망되고 있다. 본 연구에서는 평균해수면 상승에 따른 극치조위 자료에 대한 비정상성 빈도분석을 수행하였다. Mann-Kendall(MK) 검정 결과 연평균조위(annual average tide)의 경우 17개 지점에서 경향성이 통계적으로 유의한 것으로 나타났으며, 연극치 조위의 경우에는 7개 지점에서 유의한 것으로 나타났다. 비정상성 빈도 해석 결과 2100년에 한반도 연안의 극치 해수면 변화는 최소 60.33 mm에서 최대 214.90 mm까지 증가하는 것으로 분석되었다.

• Journal of Periodontal and Implant Science
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• 제40권5호
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• pp.244-248
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• 2010

Purpose: The purpose of this study was to radiographically evaluate marginal bony changes in relation to different vertical positions of dental implants. Methods: Two hundred implants placed in 107 patients were examined. The implants were classified by the vertical positions of the fixture-abutment connection (microgap): 'bone level,' 'above bone level,' or 'below bone level.' Marginal bone levels were examined in the radiographs taken immediately after fixture insertion, immediately after second-stage surgery, 6 months after prosthesis insertion, and 1 year after prosthesis insertion. Radiographic evaluation was carried out by measuring the distance between the microgap and the most coronal bone-to-implant contact (BIC). Results: Immediately after fixture insertion, the distance between the microgap and most coronal BIC was $0.06{\pm}0.68\;mm$; at second surgery, $0.43{\pm}0.83\;mm$; 6 months after loading, $1.36{\pm}0.56\;mm$; and 1 year after loading, $1.53{\pm}0.51\;mm$ ($mean{\pm}SD$). All bony changes were statistically significant but the difference between the second surgery and the 6-month loading was greater than between other periods. In the 'below bone level' group, the marginal bony change between fixture insertion and 1 year after loading was about 2.25 mm, and in the 'bone level' group, 1.47 mm, and in 'above bone level' group, 0.89 mm. Therefore, the marginal bony change was smaller than other groups in the 'above bone level' group and larger than other groups in the 'below bone level' group. Conclusions: Our results demonstrated that marginal bony changes occur during the early phase of healing after implant placement. These changes are dependent on the vertical positions of implants.