• Title/Summary/Keyword: National Technology

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Identification of a Bromodomain-containing Protein 2 (BRD2) Gene Polymorphic Variant and Its Effects on Pork Quality Traits in Berkshire Pigs

  • Lee, Dong Ju;Hwang, Jung Hye;Ha, Jeongim;Yu, Go Eun;Kwon, Seulgi;Park, Da Hye;Kang, Deok Gyeong;Kim, Tae Wan;Park, Hwa Chun;An, Sang Mi;Kim, Chul Wook
    • Food Science of Animal Resources
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    • v.38 no.4
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    • pp.703-710
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    • 2018

  • Bromodomain-containing protein 2 (BRD2) is a nuclear serine/threonine kinase involved in transcriptional regulation. We investigated the expression and association of the BRD2 gene as a candidate gene for meat quality traits in Berkshire pigs. BRD2 mRNA was expressed at relatively high levels in muscle tissue. Statistical analysis revealed that the c.1709G>C polymorphism of the BRD2 gene was significantly associated with carcass weight, meat color ($a^*$, redness), protein content, cooking loss, water-holding capacity, carcass temperatures 4, 12 and 24 h postmortem, and the 24 h postmortem pH in 384 Berkshire pigs. Therefore, this polymorphism in the porcine BRD2 gene may be used as a candidate genetic marker to improve meat quality traits in pigs.

  • https://doi.org/10.5851/kosfa.2018.e7 인용 PDF KSCI

A specific butyrylcholinesterase inhibitor from the fruits of Evodia officinalis

  • Kim, Young-Sup;Kim, Jeoung-Seob;Kim, Seong-Kie;Heor, Jung-Hee;Lee, Woo-Lak;Lee, Bong-Ho;Choi, Byuoung-Wook;Ryu, Geon-Seek;Park, Eun-Kyung;Ryu, Shi-Yong
    • Proceedings of the PSK Conference
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    • 2002.10a
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    • pp.377.1-377.1
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    • 2002

  • Neuroscience and molecular biology studies show that inappropriate butyrylcholinesterase (BuChE) activity as well as acetylcholinesterase (AChE) activity increases the risk and/or progression of Alzheimer's disease. BuChE may also regarded to participate in the transformation of Abeta (${\beta}$-amyloid) from an initially benign form to an eventually malignant form associated with neuritic tissue degeneration and clinical dementia. (omitted)

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