• 성인간호학회지
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• 제27권1호
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• pp.106-116
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• 2015

Purpose: The purpose of this review was to assess the quality and to evaluate the effectiveness of music interventions in reducing agitation in older adults with dementia. Methods: Randomized controlled studies and randomized crossover studies were identified by searching MEDLINE, EMBASE, CINAHL, PsycINFO, AGELINE, Cochrane Central Register of Controlled Trials, Korea Med, Kmbase, RISS, National Assembly Digital Library, KISS, and RICH. Two reviewers independently retrieved articles, extracted data, and assessed the quality of studies. Results: In total, 10 studies were selected from 1095 unique citations. All included studies were conducted in long term care settings. Overall, risk of bias for included studies was low to moderate. The weighted average effect size across studies was -0.39 (95%CI [-0.69, -0.10], p=.009, $I^2=63%$). Music therapy was effective to reduce agitation of the older adults with dementia. Conclusion: Music intervention can be an effective non-pharmacological intervention for the reduction of agitation in dementia. Future studies need to use rigorous research method and to provide description of research methods in greater detail. In addition, future studies are required to explore the effects of music therapy according to severity of agitation and dementia.

• Child Health Nursing Research
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• 제25권1호
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• pp.56-64
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• 2019

Purpose: This study was conducted to obtain data for the development of an effective fall risk assessment tool for pediatric inpatients through a systematic review and meta-analysis of the diagnostic test accuracy of existing scales. Methods: A literature search using Medline, Science Direct, CINAHL, EMBASE, and the Cochrane Library was performed between March 1 and 31, 2018. Of 890 identified papers, 10 were selected for review. Nine were used in the meta-analysis. Stata version 14.0 was used to create forest plots of sensitivity and specificity. A summary receiver operating characteristic curve was used to compare all diagnostic test accuracies. Results: Four studies used the Humpty Dumpty Falls Scale. The most common items included the patient's diagnoses, use of sedative medications, and mobility. The pooled sensitivity and specificity of the nine studies were .79 and .36, respectively. Conclusion: Considering the low specificity of the pediatric fall risk assessment scales currently available, there is a need to subdivide scoring categories and to minimize items that are evaluated using nurses' subjective judgment alone. Fall risk assessment scales should be incorporated into the electronic medical record system and an automated scoring system should be developed.

• The Plant Pathology Journal
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• 제22권4호
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• pp.323-328
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• 2006

Serratia marcescens W1, isolated from cucumber-cultivated soil in Suwon, Korea, evidenced profound antifungal activity and produced the extracellular hydrolytic enzymes, chitinase and protease. In order to isolate the antifungal genes from S. marcescens W1, a cosmid genomic library was constructed and expressed in Escherichia coli. Transformants exhibiting chitinase and protease expression were selected, as well as those transformants evidencing antifungal effects against the rice blast fungus, Magnaporthe grisea, and the cucumber leaf spot fungus, Cercospora citrullina. Cosmid clones expressing chitinase or protease exerted no inhibitory effects against the growth of fungal pathogens. However, two cosmid clones evidencing profound antifungal activities were selected for further characterization. An 8.2 kb HindIII fragment from these clones conditioned the expression of antagonistic activity, and harbored seven predicted complete open reading frames(ORFs) and two incomplete ORFs. The deduced amino acid sequences indicated that six ORFs were highly homologous with genes from S. marcescens generating pyrroloquinoline quinone(PQQ). Only subclones harboring the full set of pqq genes were shown to solubilize insoluble phosphate and inhibit fungal pathogen growth. The results of this study indicate that the functional expression of the pqq genes of S. marcescens W1 in E. coli may be involved in antifungal activity, via as-yet unknown mechanisms.

• 대한한방부인과학회지
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• 제29권2호
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• pp.47-66
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• 2016

Objectives : The purpose of this study was to present the clinical practice guidelines for breast cancer through the analysis of existing clinical practice guidelines in Western and Chinese medicine. Methods : The literature search was performed regarding conventional and integrative medical treatment of breast cancer using Google Scholar, KIOM OASIS, PUBMED and Jisan library of Daejeon university. Results : Breast cancer is the fifth most common cancer in Korea. Recent studies revealed that combining conventional and integrative medical treatment can reduce the sequela of surgical operation and improve survival rate. However there isn’t still a systemic clinical guideline for breast cancer in korean medicine. This study will be a preliminary study to establish clinical practice guidelines of Korean Medicine for breast cancer.Conclusions : Further objective and systemic clinical studies related to Korean Medicine are needed to develope more advanced clinical practice guidelines of breast cancer.

• 한국문헌정보학회지
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• 제28권
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• pp.287-299
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• 1995

지금까지 국내 연구자들이 SCI 학술지에 발표한 의학논문의 수가 아주 미미하기 때문에 전 세계 학자들이 발표한 SCI 전체논문 중 한국논문이 차지하는 비중은 지극히 낮은 것으로 보인다. 따라서, 본 연구에서는 1980년부터 1990년 사이에 국내에 있는 의학 관련기관의 연구자들이 SCI 학술지에 발표한 논문이 SCI 전체 논문 중 차지하는 비중(Percentage Contribution from Korea to SCI Database)을 47개 의학분야별로 조사하였다. 또한. 본 연구에서는 "국제적으로 영향력 있는 학술연구 활동실적(i.e., Mainstream Productivity)"이 타 분야보다 뛰어난 한국의 의학분야를 밝히기 위하여. SCI 학술지에 발표된 모든 한국 의학논문 중 한 분야의 논문이 자치하는 몫(Percentage Share)을 SCI 전체 논문 중 그 분야의 논문이 차지하는 몫으로 나누어 그 상대적 크기를 분석함으로써, 우리나라 학자들의 Mainstream Productivity Ratio(R)를 각 분야별로 측정하였다. (R=1은 SCI 의학 학술지에 발표된 모든 논문 중에서 어떤한 분야의 논문이 차지하는 비율만큼 한국에서도 그 분야의 논문이 SCI 학술지에 투고되었다는 의미이다.) 1980년에서 1990년 사이에 한국 학자들에 의하여 SCI에 발표된 의학논문이 SCI 전체 의학논문 중에서 차지하는 비율은 $0.051\%$였다. 각 의학 분야별로는, Biotechnology & applied microbiology의 기여도가 $0.8\%$를 차지하여 한국 최고를 기록하였다. 전 세계 문헌의 $1\%$ 이상을 생산한 의학 분야는 없었다. 전 세계 문헌의 $0.1\%$ 이상을 SCI 학술지에 게재한 의학분야는 47개 중 6개인데, 위에 언급한 Biotechnology & applied microbiology를 제외하면 $0.1\%$에서 $0.2\%$ 사이의 기여도를 보였다. 최다 편수의 논문을 낸 Pharmacology 8l Pharmacy$(0.075\%)$나 두 번째로 논문수가 많았던 Biochemisty & molecular biology$(0.054\%)$의 기여도는 $0.1\%$에 미치지 못하였다. 조사대상이 된 47개 의학분야 중 27개 분야에서 예상된 것보다 상대적으로 적은수(R<1)의 한국 논문이 SCI 학술지에 게재되었다. Mainstream Productivity Ratio가 3보다 큰 분야는 4개인데, 그 중 Biotechnology & applied microbiology는 R=15.63으로 아주 월등한 논문 발표실적을 올렸다. Dermatology & venereal diseases(3.02)와 Engineering, biomedical(3.75)도 국제적으로 영향력 있는 학술지에 논문 발표실적이 뛰어난 의학분야이다.

• 보건의료산업학회지
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• 제13권4호
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• pp.33-44
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• 2019

Objectives: This study aimed to analyze the papers on nursing in the KJHSM (Korean Journal of Health Service Management) (2007-2018), to identify the research trends and to help the future development of nursing research. Methods: The data collection was carried out from September 1, 2019 to September 30, 2019. The 78 copies of the original text were provided by the KSHSM website, DBpia, and NDSL (National Digital Science Library) electronic database. Results: Forty-seven studies had a non-experimental design, with most having a descriptive research design (89.3%). The most common participants were nurses (55.7%) and nursing college students (26.1%). A questionnaire was the most commonly used research tools (96.2%) and data collection methods (95.0%). The major keywords were the terms included in the environmental domain among the meta-paradigms of nursing (43.6%). Conclusions: In order to expand the quantity and quality of nursing science in the KSHSM, efforts are needed to improve the quality of research participants, research tools, and sampling methods.

• 전자공학회논문지CI
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• 제38권6호
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• pp.82-92
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• 2001

본 논문은 셀룰러 폰, PDA, 노트북 등과 같은 휴대 단말 시스템에서 내장형으로 사용될 수 있는 32비트 RISC 코어 구현에 대해서 기술하였다. RISC 코어는 ARM$\circled$V4 명령어 셋을 따르며 전형적인 5단 파이프 라인으로 동작한다. 또한 보다 향상된 코드 밀도를 위해 Thumb 코드를 지원하고, 파이프라인 레지스터의 동적 전력 관리 기법을 사용한다. RTL 수준에서 VHDL로 모델링된 코어는 ADS의 ARMulator와 비교 검증되었으며 평균 CPI는 1.44이다. 검증이 완료된 코어는 $0.6{\mu}m$ CMOS 1-poly 3-metal 셀라이브러리를 사용하여 합성 및 레이아웃되었으며 크기는 약 41,000 게이트이고, 예상 동작주파수는 45 MHz이다.

• Plant Resources
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• 제8권1호
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• pp.52-59
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• 2005

A cDNA, PSOD1, encoding cytosolic copper/zinc superoxide dismutase (CuZn-SOD) was cloned and characterized from a full length cDNA library prepared from Populus alba${\times}$Populus glandulosa cultured in vitro. A PSOD1, is 725 nucleotides long and has an open reading frame of 459 bp with 152 amino acid residues (pI 5.43). The deduced amino acid sequence of PSOD1 perfect matched to the previously reported CuZn-SOD (CAC33845.1). Consensus amino acid residues (His-45, -47, -62, -70, -79, -119) were involved in Cu-, Cu/Zn-, and Zn- binding ligands. The deduced amino acid sequence of PSOD1 exhibited the high level of similarity from 100 to $85\%$ among previously registered SOD genes. The expression of PSOD1 in poplar increased at the 1 mM $H_{2}O_2$ and drought stress during 30 min and 60 min, but the ozone treated poplar increased at 30 min in the early time and then decreased at 60 min.

• Plant Resources
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• 제8권1호
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• pp.1-8
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• 2005

A type 3 metallothionein cDNA (PMT3a) from ozone-treated Populus alba${\times}$Populus glandulosa cDNA library has been isolated and characterized. A PMT3a cDNA is 459 nucleotides long and has an open reading frame of 201 bp with a deduced amino acid sequence of 66 residues (pI 4.94). The deduced amino acid sequence of PMT3a matched to the previously reported metallothionein genes. The deduced amino acid sequence of PMT3a showed the $86\%$ identity with P. balsamifera ${\times}$P. deltoides. Expression of PMT3a by the RT-PCR was increased 60 min than 30 min after drought treatment. The ozone treated poplar increased at 30 min in the early time and then decreased at 60 min.

• 정보관리연구
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• 제35권3호
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• pp.1-28
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• 2004

21세기는 지식과 정보를 활용하여 자국의 인적자원개발이 국가 경쟁력의 초석이 되고 있다. 국가지식정보인프라 통합 정보망 구축을 통하여 지식과 정보의 생산, 유통 및 활용을 극대화할 수 있다. 지식기반사회에서 인적자원개발를 위한 기본적인 정보망은 교육, 연구, 노동시장, 산학협동 그리고 평생교육 정보망으로 구성된다. 이들 영역의 정보망에 대한 현황과 문제점 분석을 기반으로 하여 체계적인 통합 정보망 구축 방안을 제시하고자 한다. 국가 지식정보인프라 통합 정보망 구축 방향을 정보기반인프라와 정보지원인프라로 구분하여 제시하고 있다. 정보기반인프라를 위하여 지식과 정보에 대한 디지털화의 촉진, 접근성 향상, 컨텐츠 개발 등이 필요하며, 정보지원인프라를 위해서는 법적 제도적 기반 정비, 행 재정 지원체제 정비 그리고 다양한 인적자원개발 정책이 요구된다.