• Journal of Microbiology and Biotechnology
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• v.28 no.1
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• pp.157-164
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• 2018

Francisella tularensis (FT), a highly infectious pathogen, is considered to be a potential biological weapon owing to the current lack of a human vaccine against it. Tul4 and FopA, both outer membrane proteins of FT, play an important role in the bacterium's immunogenicity. In the present study, we evaluated the immune response of mice - humanized with human CD34+ cells (hu-mice) - to a cocktail of recombinant Tul4 and FopA (rTul4 and rFopA), which were codon-optimized and expressed in Escherichia coli. Not only did the cocktail-immunized hu-mice produce a significant human immunoglobulin response, they also exhibited prolonged survival against an attenuated live vaccine strain as well as human T cells in the spleen. These results suggest that the cocktail of rTul4 and rFopA had successfully induced an immune response in the hu-mice, demonstrating the potential of this mouse model for use in the evaluation of FT vaccine candidates.

• KIISE Transactions on Computing Practices
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• v.21 no.3
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• pp.247-256
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• 2015

Since the Gulf War, air power has played a key role. However, the effect of high-tech weapons, such as laser-guided bombs and electronic optical equipment, drops significantly if they do not match the weather conditions. So, aircraft that are assigned to carry laser-guided bombs must replace these munitions during bad weather conditions. But, there are no objective criteria for when weapons should be replaced. Therefore, in this paper, we propose an algorithm to predict the hit rate of laser-guided bombs using cloud image processing. In order to verify the accuracy of the algorithm, we applied the weather conditions that may affect laser-guided bombs to simulated flight equipment and executed simulated weapon release, then collected and analyzed data. Cloud images appropriate to the weather conditions were developed, and applied to the algorithm. We confirmed that the algorithm can accurately predict the hit rate of laser-guided bombs in most weather conditions.

• Journal of the Korea Society for Simulation
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• v.22 no.1
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• pp.31-40
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• 2013

Recent development in science and technology has modernized the weapon systems of ROKN (Republic Of Korea Navy). Although the cost of purchasing, operating, and maintaining the cutting-edge weapon systems has been increased significantly, the national defense expenditure is under a tight budget constraint. In order to maintain the availability of ships with low cost, we need an efficient and scientific method for managing repairable parts. In this study, we propose a simulation model that computes the availability of ship's repairable parts. Our model is based on the METRIC (Multi Echelon Technique Repairable Item Control) model and extends to five sub-models to reflect the realistic situations that arise in the navy, such as planned maintenance, condemnation, lateral transshipment, and cannibalization. We have performed simulations to compute the availability of repairable parts while setting the part-level consistent throughout the five models and carried out two sensitivity analyses. The simulation results show the differences in the part availability in different models. The experiments confirm our claim that ROKN needs an inventory management system that captures the operational characteristics of the navy.

• Journal of the military operations research society of Korea
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• v.33 no.1
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• pp.135-155
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• 2007

A performance specification states requirements in terms of the required results, such as performance, environment and interchangeability, but without stating the methods for achieving the required results, such as material and process. therefore the performance specification is applied to attain economic efficiency and high reliability by using the advanced commercial Technology for the weapon systems and The development of performance specification and conversion into performance specification have been activated in the advanced nations. The Ministry of National Defence of Korea has regulated the specification to make performance type in developing specification and prepared performance specification guide. but the result of the development of and conversion into performance specification is very unsatisfactory, To efficiently develop and convert into performance specification, this study gives the way of market research, the creation of the performance specification from development of weapon system and part localization, the process and method for conversion of detail specification into performance specification, the use of hybrid type of performance and detail specification.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.15 no.5
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• pp.2724-2731
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• 2014

As the future national defense plan of government focus on advanced weapon system, military maintenance facility becomes more important. However, military maintenance facility has been managed by director's experience and simple mathematical calculation until now. Thus, the optimization for the management of military maintenance facility is suggested by more scientistic and logical methods in this study. The study follows the procedure below. First, simulation is designed according to the analysis of military maintenance facility. Second, independent variable and dependent variable are defined for optimization. Independent Variable includes the number of maintenance machine, transportation machine, worker in the details of military maintenance facility operation, and dependent variable involves total maintenance time affected by independent variable. Third, warmup analysis is performed to get warmup period, based on the simulation model. Fourth, the optimal combination is computed with evolution strategy, meta-heuristic, to enhance military maintenance management. By the optimal combination, the management of military maintenance facility can gain the biggest effect against the limited cost. In the future, the multipurpose study, to analyze the military maintenance facility covering various weapon system equipments, will be performed.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.24 no.1
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• pp.120-129
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• 2020

This paper aims to benchmark the United States' LRIP, the country's initial production policy, and provide a Korean version of such policy which reflects the circumstances of the country's weapon system research & development(R&D) and acquisition procedures. The research suggests measures to improve the country's initial production policy in a direction that the policy could execute two stage continuously: (1) employment test & evaluation(OT&E), conducted on prototypes during the development stage, and (2) field employment tests(FT), conducted on initial products during the production stage. In addition, the research provides an equation calculating the optimal number of initial test products to be produced, applying statistical theories of t-distribution. The research aims to be used a reference to calculate the optimal number of initial products to be produced for testing in order to improve future national defense acquisition systems and the stable R&D of weapons systems.

• Journal of the Korea Society for Simulation
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• v.20 no.3
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• pp.101-109
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• 2011

M&S in the field of national defense is a battle system has been highly spotlighted for obtaining weapon systems, analyzing and experimentation of battle effects to reduce costs, time, and risks. It is classified as Campaign, Mission, Engagement, and Engineering levels by detail of description. In engagements, many situations on the battle field which are really unpredictable are required to be considered on the view of diverse tactics. Thus, engagement simulation is in demand to use for forecasting real-world battle situations by inserting various components which consists of real engaging situations into virtual local battle field. While developing the engagement simulation, adopting the concept of agent-based simulation gives it benefits which are improved autonomy, composability, and reusability of entities. It means reducing the time, cost and effort to develop the simulations. This paper concentrates on the framework of multi-agent based engagement simulation using Cougaar Architecture.

• Journal of the Korean Society of Manufacturing Process Engineers
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• v.17 no.6
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• pp.170-176
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• 2018

Recently, weapon system requires personal protection products due to the explosion of rapid-fire explosion, which is considered to be multi threat in modernization, complication and war against terrorism. However, the conventional Korean military bullet protection helmets are not suitable for wearing convenience and combatant interoperability in terms of ergonomic. In this paper, we propose a suitable 3D Scanning method for the head, and compare the measured 3D dimension with the existing 2D measurement value to identity the reliability. Reverse engineered soldier head using the quick surface method was realized with a perfect free-form surface and satisfactory tolerance range (${\pm}0.2mm$). Through the comparison of 3D and 2D measured head dimensions, the absolute error value was 0.73 mm on average and relative error was 0.35 %, confirming the high accuracy of the 3D scan modeling. Also, quick surface method using 3D scanner is suggested a fast and accurate skill for ergonomics in obtaining the head modeling needed for military's personal bullet protection helmet design.

• Journal of Korean Society for Quality Management
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• v.47 no.1
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• pp.187-198
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• 2019

Purpose: In this study, a reliability prediction based reliability growth management is suggested especially for the early development phase of a system and the case study of surveillance system is given. Methods: The proposed reliability prediction based reliability growth management procedures consists of 7 Steps. In Step 1, the stages for reliability growth management are classified according to the major design changes. From Step 2 to Step 5, system reliability is predicted based on reliability structures and the predicted reliabilities of subsystems (Level 2) and modules (Level 3). At each stage, by comparing the predicted system reliability with that of the previous stage, the reliability growth of the system is checked in Step 6. In Step 7, when the predicted value of sustem reliability does not satisfy the reliability goal, some design alternatives are considered and suggested to improve the system reliability. Results: The proposed reliability prediction based reliability growth management can be an efficient alternative for managing reliability growth of a system in its early development phase. The case study shows that it is applicable to weapon system such as a surveillance system. Conclusion: In this study, the procedures for a reliability prediction based reliability growth management are proposed to satisfy the reliability goal of the system efficiently. And it is expected that the use of the proposed procedures would reduce, in the test and evaluation phase, the number of corrective actions and its cost as well.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.16 no.12
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• pp.8314-8324
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• 2015

It has been recognized that in keeping the national defense capability on a leading edge, not only the continued production of weapon systems but also the associated maintenance and upgrades are becoming the subjects of great importance. Based on systems engineering process, the domestic acquisition programs for weapons systems led by DAPA have made some advancement where both new systems development and systems upgrade have attracted attention. On the other hand, as a useful type of domestic acquisition the foreign purchase program has been conceived as a process of simply buying needed weapons from abroad. Therefore, if some degree of development is necessary in system upgrades by foreign purchase, many problems turned out to exist. To study a remedy is the objective of this paper. The issues are analyzed first and then a relevant process is proposed based on a systems engineering method. Also included in the improved process is on how to generate a requirement document and the corresponding template to meet the goals of the upgrades by development. By applying the proposed process and template in the foreign purchase upgrade programs, derivation of more appropriate requirements can be expected, thereby offering effective management of programs and target goals.