• Clinical and Experimental Pediatrics
• /
• v.46 no.12
• /
• pp.1266-1270
• /
• 2003

The advance of the immunobiology clarifies the nature of non-Hodgkin's lymphoma(NHL). In addition the proceed in the immunophenotyping renders the classification of NHL. According to the Revised European American Lymphoma(REAL) classification, classified by the etiologic factors, molecular biological characteristics, immunophenotype, cytogenetics and histologic feature, nasal T/NK-cell lymphoma(=angiocentric lymphoma) belongs to the category of peripheral T-cell and natural killer cell lymphoma. Nasal T/NK-cell lymphoma is a distinct clinicopathologic entity characterized by progressive necrotic lesions in the nasal cavity, nasopharynx, and palate. The cellular origin of this tumor has been controversial. Although most nasal T/NK-cell lymphomas are of NK-cell lineage, being CD56+, negative for surface CD3(Leu4), and unassociated with rearrangements of the T-cell receptor genes, other minor variants have been reported. This lymphoma is a rare disease and usually experienced in adult. Recently, we experienced a rare type lymphoma, nasal T/NK-cell lymphoma, in 14 years old boy. His soft mass occupied the right nasal cavity including the nasal septum and turbinate. Pathologically this nasal mass showed the infiltration into the vascular wall, illustrating angiodestructive lesion. The cellular origin was NK-cell lineage, being CD56+ and negative to CD3. Now, we report the case with a brief review of related literatures.

• Korean Journal of Head & Neck Oncology
• /
• v.32 no.2
• /
• pp.51-54
• /
• 2016

Schwannomas are benign neurogenic tumors arising from the peripheral nerve sheath and rare in the nasal cavity and paranasal sinus. About 4% of schwannomas in the head and neck area arise in the sinonasal cavity. As unilateral nasal masses in the nasal cavity and paranasal sinus, schwannomas are likely to be mistaken for more common lesions such as nasal polyps or mucoceles. We recently experienced a case of schwannoma on the ethmoid sinus in a 33-year-old male which was surgically removed. Herein, we report this unusual case of schwannoma on the ethmoid sinus with a brief review of literature.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
• /
• v.32 no.4
• /
• pp.151-161
• /
• 2019

Objectives : This report was performed to observe the effects of bloodletting therapy on the rhinitis patients. Methods : 2 patients with rhinitis were treated by bloodletting therapy. We evaluated the pre-and post-treatment symptoms by NRS(numbering rating scale) and TNSS(total nasal symptom score). Results : After treatment, the symptoms of rhinitis and NRS were decreased and TNSS was improved. Conclusions : Bloodletting therapy in nasal cavity is effective to Rinitis.

• Korean Journal of Otorhinolaryngology-Head and Neck Surgery
• /
• v.61 no.11
• /
• pp.624-629
• /
• 2018

Low-grade fibromyxoid sarcoma (LGFMS), a soft tissue tumor that has high recurrence and metastasizing potential, rarely occurs in the head and neck region. Therefore, the treatment for LGFMS in the facial area is challenging in terms of cosmetic and functional maintenance. The authors report a case of LGFMS in the posterior nasal cavity. It was completely removed in parallel with the nasal endoscopic and oral approach, but the lower margin was closed by preserving the soft palate. The patient is well without any recurrence or metastasis after 5 years of follow-up.

• Korean Journal of Bronchoesophagology
• /
• v.14 no.1
• /
• pp.46-49
• /
• 2008

Neurofibroma is a neurogenic tumor arising from schwann cells or peripheral tissues of nerve sheaths. Neurofibroma rarely occurs as a solitary lesion but mostly occurs as part of neurofibromatosis and reports of neurofibromas developed in the nasal cavity or paranasal sinus are very rare. We report on a case of neurofibroma of the nasal cavity treated by endoscopic surgery. Preoperative computed tomography(CT), and punch biopsy suggested that the tumor was benign neurogenic tumor cofined to right nasal cavity. The tumor was removed with endoscopic surgery completely, and confirmed as neurofibroma by histological and immunohistochemical examination. We discuss the clinical and pathological characters of neurofibroma arising in the nasal septum.

• Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics
• /
• v.21 no.2
• /
• pp.128-132
• /
• 2010

Background and Objectives : This study was designed to examine the effect of nasal cavity surgery on voice in terms of nasalance by using subjective test, Visual analogue scale (VAS) and Nasometer and compare the pre op and post op results among patiets with nasal cavity disease. Materials and Method : From April 2009 to November 2009, data of thirty one patients who underwent nasal cavity surgery were prospectively evaluated. 24 males and 7 females with age range between 12 years to 80 years old (average 34 years old) were chosen. VAS was questioned to patients group before, after 1 week, after 1 month, and after 3 months from the surgery. Nasometer, was also conducted. Results: After the surgery symptoms like nasal obstruction, mouth breath, snoring, and sleep apnea were all improved. Improvements for nasal obstruction and mouth breath were observed statistically in post operative day (POD) 1 month and POD 3 months. Also snoring was improved statistically in POD 1 month. Objective nasalance test showed increases in a single and double vowel for POD 3 months. Only /je/ sound statistically-significant increased in all post operative periods. Nasalance increase were observed in other test results. Conclusion : All the symptoms are improved after nasal cavity surgery. Also there are some nasalance changes during whole period of study and return to the pre operative state in POD 3 months. Therefore, patients must be warned and understood about nasalance changes, and surgeons need to aware of various facts, which can affect voice changes before the surgery.

• Korean Journal of Bronchoesophagology
• /
• v.5 no.2
• /
• pp.113-118
• /
• 1999

Background & Objectives : Nasal resistance which is halfly responsible for airway resistance is known to be influenced by hypoxia, hypercapnia, exercise, pregnancy, alcohol, ammonia and smoking. Smoking is a common part of our sociocultural environment and we have many a times been introduced to its various adverse effects, which have usually been more focused on lung problems. The purpose of this study is to determine any relationship between smoking and nasal resistance and to evaluate it's effective sites. Materials and Methods : Acoustic rhinometry was performed in 25 smokers and 25 nonsmokers who had no nasal symptoms nor abnormal rhinoscopic findings, and used an acoustic rhinometry to measure the distance from nose-piece to the C-notch, cross sectional area at the C-notch, and volume of the nasal cavity from nose-piece to 7cm. The authors compared the data between the two groups. Results : The cross sectional area at the C-notch was significantly decreased(p<0.05) in smoking group. The distance to the C-notch and the volume of nasal cavity were decreased likely in smoking group but there were no significant difference(p>0.05). Conclusion : Smoking reduced the cross sectional area at the C-notch, so increased the nasal resistance. The underlying mechanisms seems to be decreased nasal mucosal reactivity and congestion of the nasal mucosa. The authors believe there should follow more studies on pathophysiologic mechanisms and the histopathologic changes which involve the effect of smoking on nasal structures.

• Korean Journal of Head & Neck Oncology
• /
• v.36 no.2
• /
• pp.65-68
• /
• 2020

Myoepithelioma is a rare benign neoplasm that mostly arises in the major salivary glands and sometimes in the minor salivary glands, which account only for less than 1% of all salivary glands neoplasms. However, its extra-salivary involvement is even rarer and only a few cases of nasal cavity myoepithelioma were reported in the English-language literature so far. In this case report, we present a 40-year-old female with unilateral nasal obstruction diagnosed as myoepithelioma of the nasal septum and treated with endoscopic sinus surgery.

• Journal of Clinical Otolaryngology Head and Neck Surgery
• /
• v.29 no.2
• /
• pp.254-258
• /
• 2018

The solitary fibrous tumor (SFT) is a mesenchymal neoplasm that is described as spindle-shaped tumor cells on a collagenous background originating from pleural tissues. Recently, extrapleural SFT has been reported in nearly all sites, including the sublingual gland, parotid gland, nasal cavity and paranasal sinuses. Complete surgical excision is primary treatment for SFT, but diagnosing SFT is not often made until immunohistochemical evaluation after surgical resection. We report that the patient, 45-year-old male, was considered as a case of inflammation polyp arising from left nasal cavity with initial biopsy, however, it has turned out to be SFT after surgical treatment.

• Archives of Craniofacial Surgery
• /
• v.18 no.2
• /
• pp.82-88
• /
• 2017

Background: Turbinate hypertrophy is one of the common causes of chronic nasal obstruction. In principle, therapeutic guidelines recommend medical treatment. Failure to treat turbinate thickening despite drug therapy may indicate the need for surgery. The main aim of this study was to determine the effect of radiofrequency surgery, among various other surgical procedures, on people with both nasal septal deviation and turbinate hypertrophy. Methods: Among people with nasal deviation who visited the subject hospital between July 2008 to July 2014, 21 people with nasal septal deviation and severe turbinate hypertrophy before their surgery had undergone septoplasty with turbinoplasty using radiofrequency combined with septoplasty. The degree of the turbinate's hypertrophy was appraised in all the patients before and after the surgery using the rhinoscopy, and acoustic rhinometry was objectively carried out. The subjective effect of the turbinoplasty using radiofrequency was explored through the visual analog scale (VAS) score. Results: The degree of contraction of the nasal mucosa after the rhinoscopy changed from Grades 3 and 4 (100%) to Grades 1 and 2 (95.2%) and Grades 3 (4.8%). The minimal cross-sectional area significantly increased from $0.44{\pm}0.07$ to $0.70{\pm}0.07cm^2$ (p<0.05). The nasal cavity volume increased from $4.79{\pm}0.49$ to $6.76{\pm}0.55cm^2$ (p<0.05). The subjective symptoms evaluated with VAS score a year after the surgery significantly improved (p<0.05). Conclusion: Turbinoplasty using Coblator with septoplasty is an effective treatment method because it expands nasal cavity, has a low incidence of complications, subjectively improves symptoms, and has short treatment duration.