• Title/Summary/Keyword: Nancy

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Conformationally Constrained Analogues of Diacylglycerol Having a Perhydrofuro[3,4-c]furan-1,4-dione Bis-${\gamma}$-butyrolactone Skeleton

  • Lee, Jee-Woo;Nancy-E. Lewin;Peter-M. Blumberg;Victor-E. Marquez
    • Archives of Pharmacal Research
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    • v.21 no.2
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    • pp.164-167
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    • 1998
  • Bis-${\gamma}$-lactones (1,2) having a perhydrofuro[3,4-c]furan-1,4-dione skeleton were designed as conformationally constrained diacylglycerol analogues. They were synthesized from D-apiose in 11 steps, and evaluated as $PKC-{\alpha}$ ligands by measuring their ability to displace bound $^3H$]PDBU from the enzyme. The compounds showed moderate binding affinities with $K_i$ values of 13.89 (${\pm}5.67$) ${\mu}M$ and 11.47 (${\pm}0.89$) ${\mu}M$, respectively. Their similar binding affinities indicate that these two bicyclic compounds were not effectively discriminated by $PKC-{\alpha}$ in terms of the direction of the side chain as other ligands built on similar bis-${\gamma}$-lactones.

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Korean Customers' Perceptions of Service in U. S, Apparel Stores : Store Polices and Customer Expectations on Satisfaction and Retail Store Service (미국의류 점포내에서의 고객서비스에 대한 한국소비자들의 지각;판매규정과 고객기대에 따른 고객 만족도 및 의류점포 서비스 인식에 미치는 영향)

  • ;Nancy F. Stanforth;Sharon J. Lennon
    • Journal of the Korean Society of Clothing and Textiles
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    • v.23 no.8
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    • pp.1170-1181
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    • 1999
  • 본 연구의 목적은 미국 의류점포의 판매규정과 고객의 점포에 대한 기대가 판매원과 소매점에 대한 만족과 평가에 미치는 영향을 조사하는 것이다 미국에 거주하는 한국 소비자들을 대상으로 먼저 시각적으로 분위기가 다른 두 점포에 따른 고객의 서비스에 대한 기대를 측정하기 위해 슬라이드를 보여주고 의류업체의 판매규정에 따른 의류에 관련된 문제상황을 설명해주는 시나리오(판매원 노력에 의한 문제 해결 또는 소비자 노력에 의한 문제해결)를 읽게 한 후 설문지를 작성하게 하였다 그 결과 업체의 판매규정이 판매원의 서비스에 대한 만족도와 평가 의류점포서비스에 대한 만족도와 평가에 영향을 미치는 것으로 나타났다.

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Beneath the Skin : A Cultural Comparison of Cosmetic Surgery and Body Image among Korean and American Females

  • Lee, Seung-Hee;Nancy A. Rudd
    • The International Journal of Costume Culture
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    • v.2 no.1
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    • pp.21-30
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    • 1999
  • The purpose of this study was to examine differences in body image and attitudes and behaviors regarding cosmetic surgery between Korean and Americans. Forty females in the U.S and 40 in Korea participated in the study by being interviewed. As a result, while Koreans had positive attitudes toward cosmetic surgery, Americans had negative attitudes. Higher incidences of cosmetic surgery were found among Koreans than among Americans. Koreans with lower body image tended to have ore tolerance toward cometic surgery. These results suggest that cosmetic surgery might be one of many ways to improve their self-esteem, Korean women with lower body image showed higher attitudes or behaviors toward cosmetic surgery than Americans.

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An Introduction to Systems Theory Approach to Accident Modeling and Its Applications (시스템 이론 기반의 안전사고 모델의 해석과 응용사례 소개)

  • Park, C.H.;Park, Y.W.
    • Journal of the Korean Society of Systems Engineering
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    • v.1 no.1
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    • pp.20-25
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    • 2005
  • This paper presents the general system theory and its applications to the safety analysis method that is a recent trend over the traditional event-driven model. This new model is known as STAMP(Systems Theory Accident Modeling and Process) proposed by Nancy G. Leveson in MIT. The new model has benefits o f systemic approaches concerning the system safety as a whole including the context it is in, its stimulants and outcomes, and its parts as well as the relationships among them in a holistic manner. The method consists of a hierarchical control structure, a process model, and the safety constraints governing the control. This paper demonstrates an example that contrasts the differences between the approaches of STAMP and the traditional safety models.

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Occupational Injury Prevention Research in NIOSH

  • Hsiao, Hongwei;Stout, Nancy
    • Safety and Health at Work
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    • v.1 no.2
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    • pp.107-111
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    • 2010
  • This paper provided a brief summary of the current strategic goals, activities, and impacts of the NIOSH (National Institute for Occupational Safety and Health) occupational injury research program. Three primary drivers (injury database, stakeholder input, and staff capacity) were used to define NIOSH research focuses to maximize relevance and impact of the NIOSH injury-prevention-research program. Injury data, strategic goals, program activities, and research impacts were presented with a focus on prevention of four leading causes of workplace injury and death in the US: motor vehicle incidents, falls, workplace violence, and machine and industrial vehicle incidents. This paper showcased selected priority goals, activities, and impacts of the NIOSH injury prevention program. The NIOSH contribution to the overall decrease in fatalities and injuries is reinforced by decreases in specific goal areas. There were also many intermediate outcomes that are on a direct path to preventing injuries, such as new safety regulations and standards, safer technology and products, and improved worker safety training. The outcomes serve as an excellent foundation to stimulate further research and worldwide partnership to address global workplace injury problems.

Acceptable Values of Kappa for Comparison of Two Groups

  • Seigel Daniel G.;Podgor Marvin J.;Remaley Nancy A.
    • 대한예방의학회:학술대회논문집
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    • 1994.02b
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    • pp.129-136
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    • 1994
  • A model was developed for a simple clinical trial in which graders had defined probabilities of misclassifying pathologic material to disease present or absent. The authors compared Kappa between graders, and efficiency and bias in the clinical trial in the presence of misclassification. Though related to bias and efficiency, Kappa did not predict these two statistics well. These results pertain generally to evaluation of systems for encoding medical information, and the relevance of Kappa in determining whether such systems are ready for use in comparative studies. The authors conclude that, by itself, Kappa is not informative Enough to evaluate the appropriateness of a grading scheme for comparative studies. Additional, and perhaps difficult, questions must be addressed for such evaluation.

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Approaches to the Analysis of Case-Control Studies of the Efficacy of Screening for Cancer

  • Weiss Noel S.;Mcknight Barbara;Stevens Nancy G.
    • 대한예방의학회:학술대회논문집
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    • 1994.02b
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    • pp.188-195
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    • 1994
  • To an increasing extent, case-control studies are being undertaken to determine if use of early detection procedures is associated with reduced mortality from cancer. The authors recommend that in such studies the analysis focus on screening activity in cases that occurs during an interval prior to diagnosis in which the cancer is believed to be detectable and still curable and to a corresponding time period in controls. This approach places a heavy burden on the investigator to estimate accurately the period during which the tumor ought to be detectable using the test in question and to sort out reliably tests done in response to signs or symptoms of the cancer from screening tests per se. Nonetheless, the authors feel that it offers the greatest ability to discern a true benefit of screening, while minimizing the numerous potential biases that can be present in this type of study.

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Tools to Prioritize Construction Phase Sustainability Actions (CPSAs) and to Measure CPSAs Implementation

  • O'Connor, James T.;Torres, Neftali;Kralik, Nancy;Woo, Jeyoung
    • Journal of Construction Engineering and Project Management
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    • v.8 no.1
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    • pp.22-30
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    • 2018
  • Achieving sustainability targets on construction projects has increasingly become one of the prime strategies for construction organizations. To provide more detailed guidance on sustainability implementation on projects, Construction Industry Institute (CII) Research Team (RT) 304 developed a catalog of the Construction Phase Sustainability Actions (CPSAs). The primary objective of this paper was the development of two support tools, the CPSA Screening Tool and the CPSA Implementation Index, that could be used to enable efficient application of CPSAs, support sustainability-related decisions, and measure CPSA implementation and performance. The authors developed the tools in four stages: conceptual, detailed planning, tool programming, and testing. The tools were then demonstrated on a capital project to confirm their efficacy and applicability. This paper presents the background, inputs and outputs, and the algorithms of each tool. The CPSA Screening Tool can prioritize the CPSAs most relevant to a project; the CPSA Implementation Index enables continuous monitoring of implementation levels.

Fixed bed column modeling of lead(II) and cadmium(II) ions biosorption on sugarcane bagasse

  • Vera, Luisa Mayra;Bermejo, Daniel;Uguna, Maria Fernanda;Garcia, Nancy;Flores, Marittza;Gonzalez, Enrique
    • Environmental Engineering Research
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    • v.24 no.1
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    • pp.31-37
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    • 2019
  • In this paper the results of the biosorption of lead(II) and cadmium(II) with sugarcane bagasse in fixed bed columns are presented. Experimental data were fitted to several models describing the rupture curve for single-component and two-component systems. The percentages of removal of lead and cadmium in single-component systems are 91% and 90%, respectively. In lead-cadmium bicomponent systems the percentage of elimination of lead was 90% and cadmium 92%. In single-component systems, Yoon-Nelson and Thomas models successfully reproduce the rupture curves. In two-component system, the Dose-Response model was the best one reproducing the experimental rupture curves in the entire measured range.

Towards cross-platform interoperability for machine-assisted text annotation

  • de Castilho, Richard Eckart;Ide, Nancy;Kim, Jin-Dong;Klie, Jan-Christoph;Suderman, Keith
    • Genomics & Informatics
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    • v.17 no.2
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    • pp.19.1-19.10
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    • 2019
  • In this paper, we investigate cross-platform interoperability for natural language processing (NLP) and, in particular, annotation of textual resources, with an eye toward identifying the design elements of annotation models and processes that are particularly problematic for, or amenable to, enabling seamless communication across different platforms. The study is conducted in the context of a specific annotation methodology, namely machine-assisted interactive annotation (also known as human-in-the-loop annotation). This methodology requires the ability to freely combine resources from different document repositories, access a wide array of NLP tools that automatically annotate corpora for various linguistic phenomena, and use a sophisticated annotation editor that enables interactive manual annotation coupled with on-the-fly machine learning. We consider three independently developed platforms, each of which utilizes a different model for representing annotations over text, and each of which performs a different role in the process.