• Title/Summary/Keyword: Na-PMP

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Application of Sweetness Inhibitor, Na$\pm$2-(4-Methoxyphenoxy)propanoic Acid, to Modify Sweetness and to Improve Shelf Life and Texture in Pound Cake (파운드케익의 단맛조절과 보존기간 및 조직감 향상을 위한 Na$\pm$2-(4-methoxyphenoxy)propanoate의 응용)

  • Lee, Sung-Kyu;Baik, Moo-Yeol;Jang, Hyuk-Rae;Park, Seung-Kook
    • Korean Journal of Food Science and Technology
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    • v.40 no.5
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    • pp.534-539
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    • 2008
  • The purpose of this study was to demonstrate the inhibitory action and quality-improvement functions of sweetness inhibitor, Na$\pm$2-(4-Methoxyphenoxy) propanoate (Na-PMP) in pound cakes. Na-PMP was first used to evaluate the intensity of sweetness in different concentrations of sucrose and fructose solutions: Na-PMP (250 and 500 ppm) was added to the model solutions of 2.5, 5.0, 7.5, and 10% sucrose and the equi-sweetness levels of fructose with the sucrose solutions. Both concentrations of Na-PMP significantly modified the sweetness intensity for both model solutions. For practical application of Na-PMP, different levels of sucrose (10, 20, and 30%) were added to the basic recipe (a control) of pound cake preparation. Excessive sweetness due to the addition of high levels of sucrose to the basic recipe was modified by the addition of Na-PMP, which resulted in equi-sweetness as the control (p<0.05). Moreover, Na-PMP improved the texture and shelf-life of the pound cake.

The Effect of Inhibitors and Catalysts in the Synthesis of 2-Hydroxyethyl Methacrylate(2-HEMA) (2-Hydroxyethyl Methacrylate(2-HEMA)의 합성에 있어서 중합억제제와 촉매의 영향)

  • Park, Byeong-Deog;Chae, Heon-Seung;Jang, Heung;Oh, Seung-Mo;Lee, Yoon-Sik
    • Applied Chemistry for Engineering
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    • v.5 no.3
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    • pp.425-430
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    • 1994
  • The effect of inhibitors and catalysts in the synthesis of 2-hydroxyethyl methacrylate(2-HEMA) was studied. As catalysts, triethylamine(TEA), $FeCl_3{\cdot}6H_2O$, $Cu(NO_3)_2{\cdot}2H_2O$, $AlCl_3$, $Na_2Cr_2O_7$were selected. p-Methoxyphenol (PMP) of aq. $NaNO_3$ solution was used as an inhibitor in polymerization. in aq. $NaNO_3$ inhibitor system, triethylamine (TEA), $FeCl_3{\cdot}6H_2O$, and $Na_2Cr_2O_7$, showed good catalytic effects. When p-methoxyphenol(PMP) was used as a polymerization inhibitor, the reaction was very sluggish and noneffective because the metal ion such as $Fe^{3+}$ or $Cr^{6+}$ was reduced by PMP. On the contrary, when aq. $NaNO_3$ was used as an inhibitor in polymerization, the reaction was very fast without deactivation of the metal catalysts.

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Characterization of two plasma membrane protein 3 genes (PutPMP3) from the alkali grass, Puccinellia tenuiflora, and functional comparison of the rice homologues, OsLti6a/b from rice

  • Chang-Qing, Zhang;Shunsaku, Nishiuchi;Shenkui, Liu;Tetsuo, Takano
    • BMB Reports
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    • v.41 no.6
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    • pp.448-454
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    • 2008
  • Two full-length cDNAs, PutPMP3-1 and PutPMP3-2, encoding PMP3 family proteins were isolated from Puccinellia tenuiflora, a monocotyledonous halophyte. Expression of both genes was induced by low temperature, salt stress, dehydration, ABA, and $NaHCO_3$. Transcripts of PutPMP3-2 were more strongly induced by these stresses relative to those of PutPMP3-1, particularly under low temperature and dehydration conditions. Expression of PutPMP3-1 and PutPMP3-2 in yeast mutants lacking the PMP3 gene can functionally complement the membrane hyper-polarization and salt sensitivity phenotypes resulting from PMP3 deletion. To compare the functions of PutPMP3-1 and PutPMP3-2, the orthologous genes in rice (OsLti6a and OsLti6b) were isolated. Both OsLti6a and OsLti6b could functionally complement the loss of PMP3 in yeast. PutPMP3-2 and OsLti6a were more effective in reversing membrane hyperpolarization than PutPMP3-1 and OsLti6b. However, the four yeast transformants each showed similar levels of salt tolerance. These results imply that these PMP3 family members don't function identically under different stress tolerance conditions.

A Study on the Measurement of the Breast Shape on Living Body by Using a PMP Moire Method (가슴형상 측정을 위한 PMP Moire 방법 활용)

  • Lee, Ga-Na;Yuk, Keun-Cheol;Kim, Byeong-Mee
    • Journal of the Korea Fashion and Costume Design Association
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    • v.11 no.2
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    • pp.11-21
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    • 2009
  • Recently, as custom-made demand about female underwear is increased, securing of a various dimension system is urgent, and satisfaction of each customer cannot be heightened with established dimensions. If we could measure shape of a living body with a fast and simple method, the custom-made demand of customers could be satisfied in the underwear as well as a clothing industry by using the method. One of the alternatives is shape measurement of the living body by a Moire fringe method. If we put a grating in front of an object to be measured and illuminate light, a Moire fringe with contour line shape is generated in the object, so we can conveniently measure object shape without touching directly by using the pattern. The Moire fringe and three-dimensional shape of the breast of the living body was acquired by a PMP method using a polygon mirror, and height and bottom width of the breast of the living body were measured by using obtained data in this study. Data of breast shape measurement through a mannequin was collected in a previous step as basic material for measuring the breast shape measurement of the living body. Three women in the twenties were selected as one of methods for measuring breast shape of a woman. As a result of the breast shape measurement of a living body A, it was measured that height of the breast was about 67.24mm and the bottom width was $13781.60mm^2$. This study is expected to contribute for collecting basic data of a female underwear industry and establishing a specification of a dimension system.

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Application of Predictive Microbiology for Microbiological Shelf Life Estimation of Fresh-cut Salad with Short-term Temperature Abuse (PMP 모델을 활용한 시판 Salad의 Short-term Temperature Abuse 시 미생물학적 유통기한 예측에의 적용성 검토)

  • Lim, Jeong-Ho;Park, Kee-Jea;Jeong, Jin-Woong;Kim, Hyun-Soo;Hwang, Tae-Young
    • Food Science and Preservation
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    • v.19 no.5
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    • pp.633-638
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    • 2012
  • The aim of this study was to investigate the growth of aerobic bacteria in fresh-cut salad during short-term temperature abuse ($4{\sim}30^{\circ}C$temperature for 1, 2, and 3 h) for 72 h and to develop predictive models for the growth of total viable cells (TVC) based on Predictive food microbiology (PFM). The tool that was used, Pathogen Modeling program (PMP 7.0), predicts the growth of Aeromonas hydrophila (broth Culture, aerobic) at pH 5.6, NaCl 2.5%, and sodium nitrite 150 ppm for 72 h. Linear models through linear regression analysis; DMFit program were created based on the results obtained at 5, 10, 20, and $30^{\circ}C$ for 72 h ($r^2$ >0.9). Secondary models for the growth rate and lag time, as a function of storage temperature, were developed using the polynomial model. The initial contamination level of fresh-cut salad was 5.6 log CFU/mL of TVC during 72 h storage, and the growth rate of TVC was shown to be 0.020~1.083 CFU/mL/h ($r^2$ >0.9). Also, the growth tendency of TVC was similar to that of PMP (grow rate: 0.017~0.235 CFU/mL/h; $r^2=0.994{\sim}1.000$). The predicted shelf life with PMP was 24.1~626.5 h, and the estimated shelf life of the fresh-cut salads with short-term temperature abuse was 15.6~31.1 h. The predicted shelf life was more than two times the observed one. This result indicates a 'fail safe' model. It can be taken to a ludicrous extreme by adopting a model that always predicts that a pathogenic microorganism will grow even under conditions so strict as to be actually impossible.

Radiological Characteristics of Materials Used in 3-Dimensional Printing with Various Infill Densities

  • Park, So-Yeon;Choi, Noorie;Choi, Byeong Geol;Lee, Dong Myung;Jang, Na Young
    • Progress in Medical Physics
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    • v.30 no.4
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    • pp.155-159
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    • 2019
  • Radiological properties of newly introduced and existing 3-dimensional (3D) printing materials were evaluated by measuring their Hounsfield units (HUs) at varying infill densities. The six materials for 3D printing which consisted of acrylonitrile butadiene styrene (ABS), a unique ABS plastic blend manufactured by Zortrax (ULTRAT), high impact polystyrene (HIPS), polyethylene terephthalate glycol (PETG), polylactic acid (PLA), and a thermoplastic polyester elastomer manufactured by Zortrax (FLEX) were used. We used computed tomography (CT) imaging to determine the HU values of each material, and thus assess its suitability for various applications in radiation oncology. We found that several material and infill density combinations resembled the HU values of fat, soft tissues, and lungs; however, none of the tested materials exhibited HU values similar to that of bone. These results will help researchers and clinicians develop more appropriate instruments for improving the quality of radiation therapy. Using optimized infill densities will help improve the quality of radiation therapy by producing customized instruments for each field of radiation therapy.

Status of Domestic and International Recommendations for Protection Design and Evaluation of Medical Linear Accelerator Facilities

  • Choi, Sang Hyoun;Shin, Dong Oh;Shin, Jae-ik;Kwon, Na Hye;Ahn, So Hyun;Kim, Dong Wook
    • Progress in Medical Physics
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    • v.32 no.4
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    • pp.83-91
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    • 2021
  • Various types of high-precision radiotherapy, such as intensity-modulated radiation therapy (IMRT), tomotherapy (Tomo), and stereotactic body radiation therapy have been available since 1997. After being covered by insurance in 2015, the number of IMRT cases rapidly increased 18-fold from 2011 to 2018 in Korea. IMRT, which uses a high-beam irradiation monitor unit, requires higher shielding conditions than conventional radiation treatments. However, to date, research on the shielding of facilities using IMRT and the current understanding of its status are insufficient, and detailed safety regulation procedures have not been established. This study investigated the recommended criteria for the shielding evaluation of facilities using medical linear accelerators (LINACs), including 1) the current status of safety management regulations and systems in domestic and international facilities using medical LINACs and 2) the current status of the recommended standards for safety management in domestic and international facilities using medical LINACs. It is necessary to develop and introduce a safety management system for facilities using LINACs for clinical applications that is suitable for the domestic medical environment and corresponds to the safety management systems for LINACs used overseas.

Application of Predictive Food Microbiology Model in HACCP System of Milk (우유의 HACCP 시스템에서 Predictive Food Microbiology Model 이용)

  • 박경진;김창남;노우섭;홍종해;천석조
    • Journal of Food Hygiene and Safety
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    • v.16 no.2
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    • pp.103-110
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    • 2001
  • Predictive food microbiology(PFM) is an emerging area of food microbiology since the later 1980’s. It does apply mathematical models to predict the responses of microorganism to specified environmental variables. Although, at present, PFM models do not completely developed, models can provide very useful information for microbiological responses in HACCP(Hazard Analysis Critical Control Point) system and Risk Assessment. This study illustrates the possible use of PFM models(PMP: Pathogen Modeling Program win5.1) with milk in several elements in the HACCP system, such as conduction of hazard analysis and determination of CCP(Critical Control Points) and CL(Critical Limits). The factors likely to affect the growth of the pathogens in milk involved storage fixed factors were pH 6.7, Aw 0.993 and NaCl 1.3%. PMPwin5.1 calculated generation time, lag phase duration, time to level of infective dose for pathogens across a range of storage (Critical Control Points) and CL(Critical Limits). The factors likely to affect the growth of the pathogens in milk involved storage temperature, pH, Aw and NaCl content. The factors likely to affect the growth of the pathogens in milk involved storage temperature, pH, Aw and NaCl content. The variable factor was storage temperature at the range of 4~15$^{\circ}C$ and the fixed factors were pH 6.7, Aw 0.993 and NaC 1.3%. PMPwin5.1 calculated generation time, lag phase duration, time to level of infective dose for pathogens across a range of storage temperature.

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A Low-Dose High-Resolution SPECT System with CdTe for Small-Animal Imaging Applications: A GATE Simulation Study (GATE 시뮬레이션을 통한 고해상도 저선량용 소동물 영상화를 위한 CdTe 검출기 기반의 SPECT 기기 연구)

  • Park, Su-Jin;Yu, A Ram;Kim, Yeseul;Lee, Young-Jin;Kim, Hee-Joung
    • Progress in Medical Physics
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    • v.24 no.3
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    • pp.162-170
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    • 2013
  • Dedicated single-photon emission computed tomography (SPECT) systems based on pixelated semiconductors are being developed for studying small animal models of human disease. To clarify the possibility of using a SPECT system with CdTe for a high resolution low-dose small animal imaging, we compared the quality of reconstructed images from pixelated CdTe detector to those from a small SPECT system with NaI(Tl). The CdTe detector was $44.8{\times}44.8$ mm and the pixels were $0.35{\times}0.35{\times}5$ mm. The intrinsic resolution of the detector was 0.35 mm, which is equal to the pixel size. GATE simulations were performed to assess the image quality of both SPECT systems. The spatial resolutions and sensitivities for both systems were evaluated using a 10 MBq $^{99m}Tc$ point source. The quantitative comparison with different injected dose was performed using a voxelized MOBY phantom, and the absorbed doses for each organ were evaluated. The spatial resolution of the SPECT with NaI(Tl) was about 1.54 mm FWHM, while that of the SPECT with a CdTe detector was about 1.32 mm FWHM at 30 mm. The sensitivity of NaI(Tl) based SPECT was 83 cps/MBq, while that of the CdTe detector based SPECT was 116 cps/MBq at 30 mm. The image statistics were evaluated by calculating the CNR of the image from both systems. When the injected activity for the striatum in the mouse brain was 160 Bq/voxel, the CNR of CdTe based SPECT was 2.30 while that of NaI(Tl) based SPECT was 1.85. The CNR of SPECT with CdTe was overall higher than that of the NaI(Tl) based SPECT. In addition, the absorbed dose was higher from SPECT with CdTe than those from NaI(Tl) based SPECT to acquire the same quantitative values. Our simulation results indicated that the SPECT with CdTe detector showed overall high performance compared to the SPECT with NaI(Tl). Even though the validation study is needed, the SPECT system with CdTe detector appeared to be feasible for high resolution low-dose small animal imaging.

Analysis of Physical Properties for Various Compositions of Reusable LMG and LCV Micelle Gel

  • Kang, Jin Mook;Lee, Dong Han;Cho, Yu Ra;Hwang, Seon Bung;Ji, Young Hoon;Ahn, So Hyun;Keum, Ki Chang;Lee, Re Na;Cho, Sam Ju;Noh, Insup
    • Progress in Medical Physics
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    • v.27 no.4
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    • pp.175-179
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    • 2016
  • In this study, we evaluated the reusable leuco malachite green (LMG) micelle gel properties dependent on various components of chemical concentration and compared with leuco crystal violet (LCV). The gels were delivered to 10, 20, 30, 40 and 50 Gy at 6 MV photon beam from linear accelerator and analyzed using spectrophotometry. We confirmed that the reusable LMG and LVC absorbance wavelength peak were made up at 630 nm and 600 nm respectively. The transparency of reusable LMG decreased with higher amount of trichloroacetic acid (TCAA) and lower reusable LMG dyes. 1 mM reusable LMG was the lowest transparency. The sensitivity was increased depending on lower trichloroacetic acid (TCAA) concentrations and the amount of suitable surfactant (Triton X-100), which was found to be 7 mM. However, we were not able to investigate sensitivity effects factor from reusable LMG dyes. The gel dosimeter containing 16 mM TCAA, 7 mM Triton X-100 gel dosimeter showed the highest sensitivity at $0.0021{\pm}0.0001cm^{-1}.Gy^{-1}$. The sensitivity of LCV was found to be higher than reusable LMG at $0.0037{\pm}0.0005cm^{-1}.Gy^{-1}$. The reusable LMG and LCV dose responses were shown to be $R^2=0.997$, $R^2=0.999$ respectively, as stable measurement results. Future research is necessary to improve dose sensitivity, dose rate dependency and gel fading with extensive chemical formulations.