• 한국CDE학회논문집
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• 제10권6호
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• pp.381-391
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• 2005

The design methodology of injection molding die has been changed from two-dimensional drafting to three-dimensional solid modeling, which is due to many advantages over the conventional methodology in terms of design modification and data associativity. In addition to the solid modeling capability, it is required for a mold designer to utilize a database management system that facilitates efficient mold design. In the paper presented is the implementation of a software program which automatically generates three-dimensional mold-bases including standard parts and slider parts, conforming to given geometric constraints. It is based on a commercial CAD system (Unigraphics NX) along with related API (application program interface) libraries. The research is expected to reduce design efforts and simplify construction of a complex three-dimensional mold-base model that is comprised of standard parts and slider parts, by use of the three-dimensional database and automatized geometric dimensioning.

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 2008년도 춘계학술대회 논문집
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• pp.175-176
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• 2008

• Mass Spectrometry Letters
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• 제12권3호
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• pp.60-65
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• 2021

As a part of the Chromosome-centric Human Proteome Project (C-HPP), we have developed a few algorithms for accurate identification of missing proteins, alternative splicing variants, single amino acid variants, and characterization of function unannotated proteins. We have found missing proteins, novel and known ASVs, and SAAVs using LC-MS/MS data from human brain and olfactory epithelial tissue, where we validated their existence using synthetic peptides. According to the neXtProt database, the number of missing proteins in chromosome 11 shows a decreasing pattern. The development of genomic and transcriptomic sequencing techniques make the number of protein variants in chromosome 11 tremendously increase. We developed a web solution named as SAAvpedia for identification and function annotation of SAAVs, and the SAAV information is automatically transformed into the neXtProt web page using REST API service. For the 73 uPE1 in chromosome 11, we have studied the function annotaion of CCDC90B (NX_Q9GZT6), SMAP (NX_O00193), and C11orf52 (NX_Q96A22).