• 한국수산과학회지
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• 제47권5호
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• pp.556-561
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• 2014

We applied a combination of most probable number-polymerase chain reaction (MPN-PCR) methods using a PCR procedure targeting the H-NS (VP1133) gene to detect Vibrio parahaemolyticus presence and density in seawater as well as within short-necked clam Ruditapes philippinarum tissues collected from Gomso Bay, Korea. In 30 seawater samples, V. parahaemolyticus levels ranged from less than 1.8 to $1.1{\times}10^3MPN/100mL$, and samples from August showed higher than those from other months. Furthermore, the levels of V. parahaemolyticus in six short-necked clam samples ranged from $7.8{\times}10^2$ to $2.1{\times}10^3MPN/100g$, approximately 2.5 times higher than in seawater samples from the corresponding month. Our results provide data on V. parahaemolyticus contamination in seawater and short-necked clam tissues, and help to improve quantitative methods of assessing V. parahaemolytcius levels.

• 한국세라믹학회지
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• 제44권1호
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• pp.23-31
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• 2007

To examine the effects of chemical admixture on the fluidity and strength development of high chloride cement, experiments were conducted in which lignosulfonate (LS), naphthalenesulfonate (NS), and polycorboxylate (PC) were each added in standard and excessive amounts, and the results were as follows. 1. Because adding KCl to NS causes a decrease in flow, adding PC is better in maintaining high cement fluidity. 2. When cement contained much chloride comes in contact with water, hydration begins 4 h after contact and securing workability becomes difficult, but by adding PC, workability can be secured to 10 h. 3. The bound water ratio and compressive strength in aging 3 days occupy $70\sim80%$ of those in aging 28 days, and the early compressive strength increases not only by adding KCl, but also by chemical admixture. 4. Although compressive strength development is excellent in NS, PC, if NS is added excessively, hydration becomes slow and while the pore structures become slightly minute, the strength development decreases due to severe setting retardation.

• 터널과지하공간
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• 제27권4호
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• pp.185-194
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• 2017

본 논문은 싱가포르 케이블 터널NS2 현장 SCL(NATM)터널구간에서 숏크리트 라이닝의 역학적 변형거동을 평가하기 위하여, 터널 막장관찰(Face Mapping)자료에 근거한 암반분류결과와 현장계측을 통한 내공변위결과를 바탕으로 NATM 터널의 공학적 거동 특성을 분석하고자 하였다. 또한 본 현장의 수직구, Adit 터널 및 Enlargement 터널의 NATM 터널 전체를 3차원 모델링하였으며, 시공중 암반분류값에 근거한 암반하중을 산정하여 3차원 유한요소해석을 실시하였으며, 해석결과를 현장계측결과와 비교 검토하였다.

• Journal of Genetic Medicine
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• 제16권1호
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• pp.1-9
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• 2019

Noonan syndrome (NS) and NS-related disorders (cardio-facio-cutaneous syndrome, Costello syndrome, NS with multiple lentigines, or LEOPARD [lentigines, ECG conduction abnormalities, ocular hypertelorism, pulmonic stenosis, abnormal genitalia, retardation of growth and sensory neural deafness] syndrome) are collectively named as RASopathies. Clinical presentations are similar, featured with typical facial features, short stature, intellectual disability, ectodermal abnormalities, congenital heart diseases, chest & skeletal deformity and delayed puberty. During past decades, molecular etiologies of RASopathies have been growingly discovered. The functional perturbations of the RAS-mitogen-activated protein kinase pathway are resulted from the mutation of more than 20 genes (PTPN11, SOS1, RAF1, SHOC2, BRAF, KRAS, NRAS, HRAS, MEK1, MEK2, CBL, SOS2, RIT, RRAS, RASA2, SPRY1, LZTR1, MAP3K8, MYST4, A2ML1, RRAS2). The PTPN11 (40-50%), SOS1 (10-20%), RAF1 (3-17%), and RIT1 (5-9%) mutations are common in NS patients. In this review, the constellation of overlapping clinical features of RASopathies will be described based on genotype as well as their differential diagnostic points and management.

• 사상체질의학회지
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• 제17권1호
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• pp.130-141
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• 2005

1. Objectives The present study was carried out to investigate the effects of Chungpyesagan-tang on the $CCI_4-induced$ Liver Damage in Rats. 2. Methods Sprague-Dawley rats were devided into 5 experimental groups : Normal, $NS+CCI_4(Solid$ extract of $CCI_4$ injection group after Normal Saline feed), $CP+CCI_4(Solid$ extract of $CCI_4$ injection group after Chungpyesagantang feed), $CCI_4+NS(Nomal$ Saline feed group after $CCI_4$ injection), $CCI_4+CP(Solid$ extract of Chungpyesagantang feed group after $CCI_4$ injection). Biochemical assays for serum enzyme activities such as AST, ALT, ALP, BUN, Creatinine, Uric Acid, Total Protein, Albumin, Total Cholesterol, Triglyceride, Glucose, and mRNA Revelation of Cytochrome p450 and activities such as LPO(Lipid Peroxidation), GSH(Glutathione), GST(Glutathione-S- Transferase), Glutathione Reductase, Glutathione Peroxidase, SOD(Superoxide Dismutase), Catalase, Hydroxyproline, and ${\beta}-Glucuronidase$ were performed. 3. Results 1) $CP+CCI_4$ showed significantly lower relation of Cytochrome p450 than $NS+CCI_4$. 2) As to LPO Hydroxyproline, $CCI_4+CP$ showed significantly lower activity than $CCI_4+NS$. 3) As to GSH GST Glutathione Peroxidase Catalase, $CP+CCI_4$ showed higher activity than $NS+CCI_4$, $CCI_4+CP$ showed significantly higher activity than $CCI_4+NS$. 4) As to Glutathione Reductase SOD, $CCI_4+CP$ showed significantly higher activity than $CCI_4+NS$. 5) As to ${\beta}-Glucuronidase$, $CP+CCI_4$ showed signficantly lower activity than $NS+CCI_4$. 4. Conclusions Chungpyesagantang has the recovering effects on the $CCI_4-induced$ Liver Damage.

• 한국산림과학회지
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• 제106권1호
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• pp.19-25
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• 2017

본 연구는 몽골 반건조지에서 질소 시비가 Populus sibirica 묘목의 생리적 특성 및 생장에 미치는 영향을 파악하고자 수행되었다. 2015년 5월, 2년생 P. sibirica 묘목을 식재하고 처리구별로 묘목 당 요소 5 g (N1), 15 g (N2), 30 g (N3) 및 N2와 같은 질소량인 황산암모늄 33 g (NS) 등을 시비하였다. 잎의 엽록소 함량은 6월과 7월에 처리구 간 유의한 차이를 보이지 않았다. 그러나 엽록소 함량이 8월에는 처리구 간 차이를 보였으며 6월과 7월에 비하여 낮게 나타났는데, 이는 잎의 노화에 의한 것으로 판단된다. 6월과 7월의 순광합성률은 N2와 NS 처리구에서 대조구보다 높게 나타났다. 6월의 증산 속도는 순광합성률의 경향과 달리 N2 처리구에서 NS 처리구보다 유의하게 높게 나타났다. 한편, 묘목의 근원경상대생장률은 NS 처리구에서만 대조구보다 유의하게 높았고, 수고 상대생장률은 처리구간 유의한 차이를 보이지 않았다. 질소 시비에 따른 엽면적 차이는 처리구 간에 유의성을 보였으나, 대조구와 각 질소 처리구 간에는 유의한 차이가 없었다. 본 연구지에서 P. sibirica 묘목의 초기 생육 증진을 위하여 요소보다 황산암모늄을 시비하는 것이 더 적합한 것으로 보인다. 요소와 황산암모늄 시비가 토양 및 묘목에 미치는 영향이 다르므로 몽골에서 황산암모늄의 적정 시비량 산정을 위한 추가 연구가 필요한 것으로 판단된다.

• Journal of Electrical Engineering and information Science
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• 제3권3호
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• pp.300-305
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• 1998

This paper describes new sense amplifier with fast sensing delay time of 0.54ns and 32kb CMOS embedded SRAM with 4.67 ns access time for a 3-V power supply. It was achieved using the sense amplifier with multiple point sensing scheme and highs peed bit-line scheme. The sense amplifier saves 25% of the power dissipation compared with the conventional one while maintaining a very short sensing delay. The SRAM uses 0.5m double-polysilicon and triple-metal CMOS process technology. A die size is 1.78${\times}$mm2.13mm.

• 대한기계학회논문집B
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• 제37권4호
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• pp.415-421
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• 2013

본 논문은 두산중공업(주)에서 개발 중인 소형 가스터빈의 축류 터빈 설계 과정을 기술하였다. 축류터빈의 설계 과정은 크게 유로설계, 익형설계, 3D 성능 계산의 세 단계로 구성되며. 최적의 유로를 설계하기 위해 자오면의 형상, 평균 반경, 블레이드간 간격, 유로 형상각 등 여러 형상 변수에 대해 통과유동계산 및 손실계산을 수행한다. 익형 설계는 유로 설계시 스팬 방향으로 계산된 입출구 유동각을 기준으로 실험상관식을 적용하여 최적의 블레이드 개수를 결정한 후 2D 익형 단면을 설계하며 2D NS 계산을 통해 캐스케이드 유동구조를 검토하여 설계한 단면의 설계적정성을 평가한다. 설계된 2D 익형 단면을 스팬방향으로 적층하여 3D 익형을 생성하고, 다단 Euler 계산, 단익렬, 다단 NS 계산을 수행하여 3D 유동 특성을 고찰한다.

• 대한전기학회논문지:전기물성ㆍ응용부문C
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• 제49권3호
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• pp.177-185
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• 2000

In this study, the characteristics of various electricity and high resistivity ash collection were measured at superimposed nanosecond pulse energization. The pulse was generated through the hydrogen thyratron. Superimposed pulse was nanosecond duration pulse that had fast pulse rising time 100[ns], short pulse width 500∼850[ns] and pulse fall time 400∼750[ns]. The results of this study are summarized as followings; Frist, compared with the DC ESP(electrostatic precipitator), superimposed pulse ESP could induce higher peak voltage, and had the about 30[%] reduction of ESP collection area and 50∼80[%] reduction of power consumption. showing the same efficiency. Second, enhancement factor H had 1.9∼3.6 with the increase of migration velocity.

• 한국식품영양학회지
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• 제11권6호
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• pp.640-646
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• 1998

For the production of nonprotein $\alpha$-glucosidase inhibitor from the Streptomyces sp. NS15 strain, effects of initial optimum pH, nitrogen sources, carbon sources, cationic metal ions, agitation speed and aeration rate were investigated. Initial optimum pH of medium was 7.0. The most effective nitrogen and carbon sources were soybean meal 2.0%(w/v) and glucose 1.6%(w/v), respectively. The cationic metal ins had no stimulating effect on inhibitory activity of $\alpha$-glucosidase except Fe2+. Agitation speed and aeration rate were effective at 400rpm and 1vvm, respectively. In the jar-fermenter cultivation for 4 days under optimal culture conditions, the culture broth showed the inhibitory acitivity of 3,200units/ml, which is 25 times higher than that of basic medium (CYM) for porcine intestinal $\alpha$-glucosidase. The inhibitory activity of $\alpha$-glucosidase reached about 3,200units/ml after 4 days of cultivation and decreased gradually for a further two days.