• Microbiology and Biotechnology Letters
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• v.26 no.5
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• pp.420-426
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• 1998

An extracellular glutamyl aminopeptidase (EC 3.4.11.7) producing bacterium was isolated from soil and identified as Bacillus licheniformis based on its morphological and physiological characteristics. The aminopeptidase was purified to homogeneity by ammonium sulfate precipitation, Phenyl Sepharose, Resource Q, and Superose 12 column chromatographies. The specific activity of the purified aminopeptidase was 9.2 unit/mg for glutamyl p-nitroanilide with 17.6 purification folds. The purified aminopeptidase had an estimated molecular mass of 64 kDa consists of two different subunits (42 kDa and 22 kDa), and its isoeletric point was 5.2 measured by isoelectric focusing. The optimum pH and temperature of the aminopeptidase were 8.0 and 55$^{\circ}C$, respectively. The aminopeptidase was inhibited by EDTA and 1,10-phenanthroline, suggesting it be a metalloenzyme. Comparing with other aminopeptidase, the enzyme showed relatively high activity against peptide having glutamic acid as N-terminal.

• Ocean and Polar Research
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• v.29 no.4
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• pp.303-310
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• 2007

2-D wavelet analysis is applied to bathymetric data from the KR1 area of Korea Deepsea Mining Area. The wavelet analysis is one of the quantitative methods to analyze the topography. The wavelet allows us to create filters to select for topography in a continuous variety of shapes, sizes, and orientation. The 2-D Linear B-spline filter, 100 BS and 100 NF, is convolved with bathymetric data to identify the location of abyssal hills and abyssal troughs in bathymetry. In addition, the 2-D derivative of Cubic B-spline filter, 60 BS and 60 NF, is applied to bathymetric data to find the slope of abyssal hill in bathymetry. These filters were rotated $5^{\circ}$ counterclockwise from NS to match the dominant orientation of seafloor lineament. Both filters result in good match with abyssal hills, troughs, and slopes. This method can apply to fault, fold, and other lineament structures description with variable size. The result of application shows that wavelet analysis of bathymetric data could be used with fundamental data of geophysical analysis.

• Journal of Pharmacopuncture
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• v.4 no.3
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• pp.7-14
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• 2001

Objective: This study was done to observe the effects on the thermal changes and side effects of Bee Venom acupuncture. The objectives are as follows; If there are remarkable local thermal changes between pre and post Bee Venom acupuncture therapy on D.I.T.I. or not. If there are those, we examine how long it' s changes are maintained, what is the adequate interval on Bee Venom acupuncture therapy, and what the reactions in a local or whole body are on that therapy. Methods: To study the local thermal changes in Bee Venom acupuncture therapy, D.I.T.I. was used. Determination of this analysis periods are pre and post-therapy(5 minutes, 1 hour, 1day,2days, 3days, 5days and 7days later). The study group was divided into two groups. One was BV group(N=19), another was NS(Normal Saline) group. The Bee Venom acupuncture was injected by 0.2ml divided into 0.05ml at the Fengmen(風門:12), Feishu(肺兪:B13), Fufen(附分:B41), Pohu(魄戶: B42) 4 points. Then, in order to analyze the clinical form, we have observed responses of 23 students whenever we checked the thermal changes of their after performing. Results: The following results were obtained. 1. In BV group, there was a significant dermatothermal difference between pre and post therapy. That difference was most remarkable in post-therapy 1 hour to lday, and was not remarkable in post-therapy 5-7days later. 2. There was no significant dermatothermal changes at NS group, but BV group had remarkable changes between operated and non operated area in post-therapy 1hour, 1day, 2days. But there was none 7 days later. 3. Among the physical reactions after Bee Venom acupuncture therapy, operated-area pain, itching, pain on moving and fatigue sign most appeared until post-therapy 3days. Itching and fatigue sign appeared until post-therapy 7days. 4. In comparison the dermatothermal changes with the physical reactions, the decrease of { CT = (Rt Temperature -Lt. Temperature) / Rt. $Temperature{\times}100$} and the disappearance of physical reactions were about the same.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.23 no.2
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• pp.281-287
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• 1999

The turbulent natural convection in the membrane type LNG carrier cofferdam with heating points has been studied by numerical method. As the numerical methods, we introduced the three turbulence model, a standard $k-{\varepsilon}$ model and two case of a low Reynolds number models. The parameters considered for this study ore number and capacity of heating points i.e., $1{\leq}Ns{\leq}12$ and $1.0{\times}10^5{\leq}Qs(W/m^3){\leq}1.0{\times}10^8$. The results of the isotherms and velocity vectors have been represented for various parameters. The temperature and velocity at upper position in the space ore shown to be higher than those at lower position. For obtaining the optimal temperatures, $20{\sim}30^{\circ}C$ in the cofferdam space, the heating capacities show $2.0{\times}10^7W/m^3$ at g-heating points and $1.0{\times}10^7W/m^3$ at 12-points. The mean temperature in the cofferdam space can be expressed as a function of number and capacity of heating points.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.30 no.6B
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• pp.387-395
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• 2005

In this paper, we propose an end-to-end mobility management and TCP flow control scheme which considers different link characteristics for vertical handover environments. The end-to-end mobility management is performed by using SIP protocol. When a mobile node moves to a new network, it informs its movement of the correspondent node by sending SIP INFO message containing a new IP address which will be used in the new network. And then the corresponding node encapsulates all packets with the new IP address and sends them to the mobile node. in general, RTT of WLAN is shorter than RTT of cdma2000. when the MN moves from WLAN network to cdma2000 network, TCP retransmission timeout will be occurred in spite of non congestion situations. Thus, TCP congestion window size will be decreased and TCP throughput will be also decreased. To prevent this phenomenon, we propose a method using probe packets after handover to estimate a link delay of the new network. We also propose a method using bandwidth ratio of each network to update RTT. It is shown through NS-2 simulations that the proposed schemes can have better performance than the previous works.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.31 no.2B
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• pp.80-90
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• 2006

WSN(Wireless Sensor Network) performs to detect and collect environmental information for one purpose. As examples, WSN is applicable for home network, patient management of a hospital, logistics management, status detection during the war and so on. The WSN is composed of a sink node and several sensor nodes and has a constraint in an aspect of energy consumption caused by limited battery resource. So many required mechanisms in WSN should consider the remained energy condition. A routing mechanism is requested to deliver the collected information to a sink considering energy efficiency in WSN. There have been many researches to establish (a) route(s) for data delivery to the sink. In this paper, we propose establishment of efficient routes. We proposed a uniform routing mechanism together with considering energy efficiency. For the routing, we define energy probability as routing metrics information and Performs suppression of exchange of control messages. In addition, we derive to uniformly consume the energy of the sensor node when establishing the routes. Also, we evaluate and analyze the energy efficiency for proposed mechanisms through NS-2 simulator.

• Applied Chemistry for Engineering
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• v.7 no.3
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• pp.597-604
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• 1996

Resin-type neutron shielding materials, KNS-115A, 115B and 115C have been fabricated to be used for spent fuel shipping cask. The base material is epoxy resin, and polypropylene, aluminium hydroxide and boron carbide are added. These shielding materials offer good fluidity at processing, which makes it possible to apply this resin shield to complicated geometric shapes such as shipping cask. Several measurements were made for the shielding materials to evaluate the shielding property, combustion characteristics, fire resistance, thermal and mechanical properties. The neutron shielding ability of the shielding materials is estimated to be better than that of foreign's shielding material, NS-4-FR, due to higher hydrogen atomic density. Other properties of the shielding materials are as follows: Onset temperatures; $267{\sim}270^{\circ}C$, thermal conductivities; $0.62{\sim}0.72W/m{\cdot}K$, combustion characteristics; <$800^{\circ}C$, ATB(average time of burning); <5sec, AEB(average extent of burning) ; <5mm, tensile strengths; $2.3{\sim}3.0kg/mm^2$, compressive strengths; $5.3{\sim}13.3kg/mm^2$, flexural strengths; $4.4{\sim}5.4kg/mm^2$.

• Bulletin of the Korean Chemical Society
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• v.30 no.11
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• pp.2626-2630
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• 2009

2'($\beta$)-Hydroxymethylated adenosine is a potent and selective inhibitor of hepatitis C virus (HCV) replication. It targets the RNA-dependent RNA polymerase of HCV, NS5B. Synthesis and antiviral evaluation of carbocyclic versions are described. The cyclopentene intermediate ($9\beta$) was successfully synthesized through sequential Johnson-Claisen orthoester rearrangement and ring-closing metathesis (RCM). Coupling of bases via a Pd(0) catalyst, selective dihydroxylation, and desilylation yielded the target nucleoside analogues. The compounds 17 and 18 were assayed for their ability to inhibit HCV RNA replication in a subgenomic replicon Huh7 cell line and showed moderate antiviral activity with toxicity up to 20.0 and 24.7 ${\mu}g/mL$, respectively.

• Journal of Acupuncture Research
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• v.19 no.5
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• pp.124-135
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• 2002

Objective : This study was done to observe the effects on the thermal changes of herbal acupuncture. There were remarkable local thermal changes between pre and post herbal acupuncture therapy on D.I.T.I. or not. If there are those, we examine how long changes of those were maintained, what is the adequate interval on herbal acupuncture therapy. Methods : D.I.T.I, was used to study the local thermal changes in herbal acupuncture therapy. Determination of this analysis periods are pre and post-therapy(1hour, 1day, 7days later). The study group was divided into six groups that are NS group(No.=20), CF group(No.=22), BU group(No.=23), BUM group(No.=19), HP group(No.=20) and BV group(No.=l9). The herbal acupuncture was injected by 0.2ml divided into 0.05ml at the Fengmen(風門: B12), Feishu(肺兪: B13), Fufen(附分: B41), Pohu(魄戶: B42) 4 points. Then, we checked the thermal changes of their point after performing. Results : The following results were obtained ; 1. In CF groups, significant dermatothermal difference between pre and post therapy was not checked, In BU group that continued until post-therapy 1day, in HP group until 1hour, in BV group until 2days. In BUM, HP and BV group, Most dermatothermal difference was checked at post-therapy 1hour, in BU group at post-therapy 1day. 2. At post-therapy 1 hour, significant dermatothermal different between pre and post therapy was checked among BU group, BUM group, HP group and BV group. At post-therapy 1day and 2days, checked among BU group, BUM group and BV group. At post-therapy 7days, not checked among all groups. The group that highest dermatothermal difference were checked is BV group.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.27 no.9
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• pp.1335-1341
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• 2003

This paper describes the process of nanoparticle synthesis by laser ablation of microparticles and consolidated sample. We have generated nanoparticles by high-power pulsed laser ablation of AI, Cu and Ag microparticles using a Q-switched Nd:YAG laser (wavelength 355nm, FWHM 6ns, fluence $0.8{\sim}2.0J/cm^2$). Microparticles of mean diameter $18{\sim}80{\mu}m$ are ablated in the ambient air. The generated nanoparticles are collected on a glass substrate and the size distribution and morphology are examined using a scanning electron microscope and a transmission electron microscope. The effect of laser fluence, collector position and compacting pressure on the distribution of particle size is investigated. To better understand the process of laser ablation of microparticle(LAM), we investigated the Nd: YAG laser-induced breakdown of Cu microparticle using time-resolved optical shadow images. Nanosecond time-resolved images of the ablation process are also obtained by laser flash shadowgraphy. Based on the experimental results, discussions are made on the dynamics of ablation plume.