• Title/Summary/Keyword: NR System

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A Study on Arterial Road Network Improvement Based on Networking Analysis (Networking 기반의 간선도로의 망기능 분석방법론 연구)

  • Jung, Kabchae;Kang, Kyeong Pyo;Kim, Jung Wan
    • Journal of Korean Society of Transportation
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    • v.31 no.1
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    • pp.47-56
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    • 2013
  • The present study proposed a methodology to analyze the networking efficiency of arterial road networks. The methodology was motivated to design three-dimensional networks and to analyze the networking ability quantitatively, which is a novel approach compared to existing methods depending on the two-dimensional network definition and the qualitative analysis for improving arterial road networks. The method considered the interdependence between high-level freeways and low-level highways, the ITS-based information for traffic and road conditions, and the physical networking. These three factors were quantified by a networking index (NI), and the networking efficiency was measured by a networking rate (NR). The present study proved that the networking efficiency (NR) was influenced by travel information sharing (i.e., ITS) and physical factors. This supports the fact that the integrated improvements of physical and ITS factors are necessary for an arterial road. The proposed method was applied for an actual arterial road network. It was found that the nation-wide NR was higher than that for the metropolitan area, which might be due to the difficulty in switching between high- and low-level networks and the lack of ITS functions in the metropolitan area.

Impact of NR1I2, adenosine triphosphate-binding cassette transporters genetic polymorphisms on the pharmacokinetics of ginsenoside compound K in healthy Chinese volunteers

  • Zhou, Luping;Chen, Lulu;Wang, Yaqin;Huang, Jie;Yang, Guoping;Tan, Zhirong;Wang, Yicheng;Liao, Jianwei;Zhou, Gan;Hu, Kai;Li, Zhenyu;Ouyang, Dongsheng
    • Journal of Ginseng Research
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    • v.43 no.3
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    • pp.460-474
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    • 2019
  • Background: Ginsenoside compound K (CK) is a promising drug candidate for rheumatoid arthritis. This study examined the impact of polymorphisms in NR1I2, adenosine triphosphate-binding cassette (ABC) transporter genes on the pharmacokinetics of CK in healthy Chinese individuals. Methods: Forty-two targeted variants in seven genes were genotyped in 54 participants using Sequenom MassARRAY system to investigate their association with major pharmacokinetic parameters of CK and its metabolite 20(S)-protopanaxadiol (PPD). Subsequently, molecular docking was simulated using the AutoDock Vina program. Results: ABCC4 rs1751034 TT and rs1189437 TT were associated with increased exposure of CK and decreased exposure of 20(S)-PPD, whereas CFTR rs4148688 heterozygous carriers had the lowest maximum concentration ($C_{max}$) of CK. The area under the curve from zero to the time of the last quantifiable concentration ($AUC_{last}$) of CK was decreased in NR1I2 rs1464602 and rs2472682 homozygous carriers, while $C_{max}$ was significantly reduced only in rs2472682. ABCC4 rs1151471 and CFTR rs2283054 influenced the pharmacokinetics of 20(S)-PPD. In addition, several variations in ABCC2, ABCC4, CFTR, and NR1I2 had minor effects on the pharmacokinetics of CK. Quality of the best homology model of multidrug resistance protein 4 (MRP4) was assessed, and the ligand interaction plot showed the mode of interaction of CK with different MRP4 residues. Conlusion: ABCC4 rs1751034 and rs1189437 affected the pharmacokinetics of both CK and 20(S)-PPD. NR1I2 rs1464602 and rs2472682 were only associated with the pharmacokinetics of CK. Thus, these hereditary variances could partly explain the interindividual differences in the pharmacokinetics of CK.

Cell ID Detection Schemes Using PSS/SSS for 5G NR System (5G NR 시스템에서 PSS/SSS를 이용한 Cell ID 검출 방법)

  • Ahn, Haesung;Kim, Hyeongseok;Cha, Eunyoung;Kim, Jeongchang
    • Journal of Broadcast Engineering
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    • v.25 no.6
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    • pp.870-881
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    • 2020
  • This paper presents cell ID (cell identity) detection schemes using PSS/SSS (primary synchronization signal/secondary synchronization signal) for 5G NR (new radio) system and evaluates the detection performance. In this paper, we consider two cell ID detection schemes, i.e. two-stage detection and joint detection schemes. The two-stage detection scheme consists of two stages which estimate a channel gain between a transmitter and receiver and detect the PSS and SSS sequences. The joint detection scheme jointly detects the PSS and SSS sequences. In addition, this paper presents coherent and non-coherent combining schemes. The coherent scheme calculates the correlation value for the total length of the given PSS and SSS sequences, and the non-coherent combining scheme calculates the correlation within each group by dividing the total length of the sequence into several groups and then combines them non-coherently. For the detection schemes considered in this paper, the detection error rates of PSS, SSS and overall cell ID are evaluated and compared through computer simulations. The simulation results show that the joint detection scheme outperforms the two-stage detection scheme for both coherent and non-coherent combining schemes, but the two-stage detection scheme can greatly reduce the computational complexity compared to the joint detection scheme. In addition, the non-coherent combining detection scheme shows better performance under the additive white Gaussian noise (AWGN), fixed, and mobile environments.

Influence of Silane Coupling Agent on Retraction Behaviors of NR Vulcanizates Reinforced with Carbon Black and Clay (실란 커플링제가 카본블랙과 점토로 보강된 천연 고무 가황물의 회복 특성에 미치는 영향)

  • Choi, Sung-Seen;Park, Byung-Ho;Kim, Wan-Soo;Kim, Wan-Doo
    • Elastomers and Composites
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    • v.40 no.2
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    • pp.112-118
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    • 2005
  • Influence of a silane coupling agent on the reatraction behaviors of NR vulcanizates reinforced with carbon black and c lay was studied. Bis-(3-(triethoxysilyl)-propyl )-tetrasulfide (TESPT) was used as a silane coupling agent. The vulcanizates containing the silane coupling agent were, on the whole, recovered faster than those without the silane coupling agent. However, for the vulcanizate with the higher clay content at low temperature region (below $-12^{\circ}C$), the vulcanizate containing the silane coupling agent was recovered slower than that without the silane coupling agent. The recovery difference of the vulcanizates with and without silane coupling agent decreased with increase of clay content. The experimental results were explained with crosslink density, modulus, and bound rubber content.

A Study on the Vulcanization System and Two-Step Foaming Properties for Natural Rubber Foam (천연고무의 가황시스템 및 성형공정에 따른 2단 발포 특성 연구)

  • Sunhee Lee;Ye-Eun Park;Dikshita Chowdhury
    • Textile Coloration and Finishing
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    • v.35 no.4
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    • pp.246-255
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    • 2023
  • In this study, we investigated for natural rubber foam to replace petrochemical-based neoprene foam. Experiments were conducted on vulcanization system and 2-step foaming process of natural rubber. The vulcanization system were EV(Efficient Vulcanization Cure), Semi-EV(Semi-Efficient Vulcanization Cure) and CV(Conventional Vulcanization Cure). In the 2-step foaming process, first molding temperature was 140℃, times were 15, 20, 25, and 30minutes, and the second molding temperature was 160℃, the times 5, 10, 15, and 20minutes. The cure and viscosity characterization were evaluated by oscillating disc rheometer (ODR) and mooney viscosmeter. Various mechanical characteristics, including hardness, tensile strength, elongation at the point of rupture, and tear strength, were quantified. Subsequently, an assessment of alterations in these mechanical attributes was conducted post-immersion in a NaCl solution. In addition degree of volume change was measured after immersing the NR foam in NaCl solution and the low-temperature permanent compression set was evaluated at 4℃. And expansion ratio and shrinkage ratio of NR foam were evaluated for 28 days. As a result the EV vulcanization system showed the least change in physical properties before and after salt water immersion, and the lowest shrinkage ratio for 28 days. In addition it was confirmed that the 2-step foaming optimum condition differed depending on the appropriate vulcanization condition.

Analysis of call blocking probability and queuing modeling using call admission control in the CDMA system with the WLAN (WLAN이 연동된 CDMA 시스템에서 Call Admission Control을 이용한 호 차단확률 분석과 Queuing 모델링)

  • 안치훈;기영민;김동구;류승문
    • Journal of the Institute of Electronics Engineers of Korea TC
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    • v.41 no.4
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    • pp.17-24
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    • 2004
  • Call blocking probabilities of streaming data service in CDMA system with access point(AP) of WLAN are analyzed for different cell geometry of base station and AP and queuing is modeled. The considered system leads to successful handoffs between the APs of WLAN. Blocking probabilities are enumerated as a function for ratio of base station and AP sizes, their locations and the number of buffer in the queue. Results show that blocking probability is not influenced by base station and AP locations but mainly by ratio of their sizes. For CDMA system of radius 100m, 5 buffers in the queue and 7㏈ noise rise(NR), in order to obtain 1% call blocking probability, a cell with hot spot of radius 20m has more 0.6Erlang than that of radius 60m.

Effect of Various Cross-linking Types on the Physical Properties in Carbon Black-Filled Natural Rubber Compound (천연고무 배합물에서 가교형태 변화가 물성에 미치는 영향)

  • Park, Byung-Ho;Jung, Il-Gouen;Park, Sung-Soo
    • Polymer(Korea)
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    • v.25 no.1
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    • pp.63-70
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    • 2001
  • The objective of this study was to investigate the effect of cure type on the processing and physical properties under conditions of similar stress-strain properties. On the carbon black filled natural rubber(NR) based compound, the induction time decreased, but the cure rate became fast with increasing loading of sulfur donor agent. Tensile strength was little affected on the curing type. However, elongation generally decreased with increasing accelerator. Effect of cure type on the blow-out properties was followings: CV

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Ovarian transcriptomic analysis of Shan Ma ducks at peak and late stages of egg production

  • Zhu, ZhiMing;Miao, ZhongWei;Chen, HongPing;Xin, QingWu;Li, Li;Lin, RuLong;Huang, QinLou;Zheng, NenZhu
    • Asian-Australasian Journal of Animal Sciences
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    • v.30 no.9
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    • pp.1215-1224
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    • 2017
  • Objective: To assess the differences in ovarian transcriptomes in Shan Ma ducks between their peak and late stages of egg production, and to obtain new transcriptomic data of these egg-producing ducks. Methods: The Illumina HiSeq 2000 system was used for high throughput sequencing of ovarian transcriptomes from Shan Ma ducks at their peak or late stages of egg production. Results: Greater than 93% of the sequencing data had a base quality score (Q score) that was not less than 20 (Q20). From ducks at their peak stage of egg production, 42,782,676 reads were obtained, with 4,307,499,083 bp sequenced. From ducks at their late stage of egg production, 45,316,166 reads were obtained, with 4,562,063,363 bp sequenced. A comparison of the two datasets identified 2,002 differentially expressed genes, with 790 upregulated and 1,212 downregulated. Further analysis showed that 1,645 of the 2,002 differentially expressed genes were annotated in the non-redundant (NR) database, with 646 upregulated and 999 downregulated. Among the differentially expressed genes with annotations in the NR database, 696 genes were functionally annotated in the clusters of orthologous groups of proteins database, involving 25 functional categories. One thousand two hundred four of the differentially expressed genes with annotations in the NR database were functionally annotated in the gene ontology (GO) database, and could be divided into three domains and 56 categories. The three domains were cellular component, molecular function, and biological process. Among the genes identified in the GO database, 451 are involved in development and reproduction. Analysis of the differentially expressed genes with annotations in the NR database against the Kyoto encyclopedia of genes and genomes database revealed that 446 of the genes could be assigned to 175 metabolic pathways, of which the peroxisome proliferator-activated receptor signaling pathway, insulin signaling pathway, fructose and mannose metabolic pathways, gonadotropin releasing hormone signaling pathway and transforming growth factor beta signaling pathway were significantly enriched. Conclusion: The differences in ovarian transcriptomes in Shan Ma ducks between their peak and late stages of egg production were elucidated, which greatly enriched the ovarian transcriptomic information of egg-producing ducks.

A Study on the Elution Mechanism of Ni(II)-Isonitrosoethylacetoacetate Imine Chelates by Reversed Phase High Performance Liquid Chromatography (역상 액체 크로마토그래피에 의한 Ni(II)-Isonitrosoethylacetoacetate Imine 유도체 킬레이트의 용리 메카니즘에 관한 연구)

  • Kim In-Whan;Choi Gang-Yeol;Lee Man-Ho;Kang Chang-Hee;Lee, Won
    • Journal of the Korean Chemical Society
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    • v.36 no.5
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    • pp.697-708
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    • 1992
  • Liquid Chromatographic behavior of Ni(II) in Isonitrosoethylacetoacetate Imine(IEAA-NR), Ni(IEAA-NH)(IEAA-NR)(R = H, CH_3, C-2H_5, n-C_4H_9, C_6H_5-CH_2) chelates were investigated by reversed-phase HPLC on Micropak MCH-5 column using methanol/water as mobile phase. The optimum conditions for the separation of Ni(IEAA-NH)(IEAA-NR) chelates were examined with respect to the effect of the flow rate, sample solvent, mobile phase strength and column temperature. It was fo$und that metal chelates were properly eluted in an acceptable range of capacity factor value(0{\le}logk'{\le}1). The dependence of the logarithm of capacity factor (k') on the volume fraction of water in the binary mobile phase as well as on the liquid-liquid extraction distribution ratio (Dc) in methanol-water/n-alkane extraction system showed the good linearties, and the dependence of the logarithm of capacity factor (k') on the column temperature and on the enthalpy exhibited the good linearties, and the compensation temperature ({\beta}) from the slope was 773.47{\circ}K. It was suggested that the retention of metal chelates was largely affected by the hydrophobic effect.

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Image Reconstruction Using Iterative Regularization Scheme Based on Residual Error in Electrical Impedance Tomography (전기 임피던스 단층촬영법에서 잔류오차 기반의 반복적 조정기법을 이용한 영상 복원)

  • Kang, Suk-In;Kim, Kyung-Youn
    • Journal of IKEEE
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    • v.18 no.2
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    • pp.272-281
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    • 2014
  • In electrical impedance tomography (EIT), modified Newton Raphson (mNR) method is widely used inverse algorithm for static image reconstruction due to its convergence speed and estimation accuracy. The unknown conductivity distribution is estimated iteratively by minimizing a cost functional such that the residual error namely the difference in measured and calculated voltages is reduced. Although, mNR method has good estimation performance, EIT inverse problem still suffers from ill-conditioned and ill-posedness nature. To mitigate the ill-posedness, generally, regularization methods are adopted. The inverse solution is highly dependent on the choice of regularization parameter. In most cases, the regularization parameter has a constant value and is chosen based on experience or trail and error approach. In situations, when the internal distribution changes or with high measurement noise, the solution does not get converged with the use of constant regularization parameter. Therefore, in this paper, in order to improve the image reconstruction performance, we propose a new scheme to determine the regularization parameter. The regularization parameter is computed based on residual error and updated every iteration. The proposed scheme is tested with numerical simulations and laboratory phantom experiments. The results show an improved reconstruction performance when using the proposed regularization scheme as compared to constant regularization scheme.