• Asian Pacific Journal of Cancer Prevention
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• 제15권21호
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• pp.9233-9239
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• 2014

Background: We aimed to evaluate the estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2) expression discordance in matched pairs of primary breast cancer and lymph node metastasis specimens and determine the effect of discordance on prognosis. Materials and Methods: Among all patients diagnosed with lymph node metastases from 2004 to 2007, primary tumors and paired lymph node metastases were resected from 209 patients. The status of ER, PR, and HER2 expression was analyzed immunohistochemically in 200, 194, and 193 patients, respectively. Discordance was correlated with prognosis. Results: Biomarker discordance between primary tumors and paired lymph node metastases was 25.0% (50/200) for ER status, 28.9% (56/194) for PR status, and 14.0% (27/193) for HER2 status. ER positivity was a significant independent predictor of improved survival when analyzed in primary tumors and lymph node metastases. Patients with PR-positive primary tumors and paired lymph node metastases displayed significantly enhanced survival compared to patients with PR-positive primary tumors and PR-negative lymph node metastases. Patients with ER- and PR-positive primary tumors and paired lymph node metastases who received endocrine therapy after surgery displayed significantly better survival than those not receiving endocrine therapy. Similalry treated patients with PR-negative primary tumors and PR-positive paired lymph node metastases also displayed better survival than those not receiving endocrine therapy. Conclusions: Biomarker discordance was observed in matched pairs of primary tumors and lymph node metastases. Such cases displayed poor survival. Thus, it is important to reassess receptor biomarkers used for lymph node metastases.

• 한국정보통신학회논문지
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• 제16권10호
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• pp.2224-2229
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• 2012

센서 데이터는 지속적으로 데이터 집합에 데이터가 삽입되기 때문에 데이터 검색을 위하여 연속 질의를 사용해야 한다. 연속 질의를 처리하기 위하여 각 센서 노드에서 질의 색인을 구축하고 질의 조건에 맞는 데이터를 전송하는 것이 필요하다. 그러나 모든 노드에 질의 조건을 전송하면 대량의 메시지가 발생하는 문제가 있다. 이 논문에서는 질의 조건 전송을 위한 메시지 횟수를 줄이기 위하여 센서노드선정 트리를 이용한 노드 선정 기법을 제안한다. 단말노드 엔트리는 각 센서 노드를 나타내며 센서 노드에서 발생하는 데이터의 영역을 정의한다. 질의가 발생하면 질의 조건과 겹치는 노드들이 선정되며 해당 노드로 질의 조건을 전송한다. 그리고 센서노드선정 트리를 구현하고 효율성을 실험하였다.

• Archives of Plastic Surgery
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• 제36권4호
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• pp.485-488
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• 2009

Purpose: Malignant melanoma of the lower extremity is well known to metastasize to the lymph nodes of the groin. However, in rare cases, the initial site of the nodal disease can be the popliteal fossa. As of yet, there has not been any report on cases with popliteal lymph node metastasis in Koreans. In the following report, authors would like to present two cases of popliteal node metastasis. Methods: A 60 - year - old male patient presented with nodular mass at his left sole. He had popliteal node metastasis detected on preoperative positron emission tomography(PET). Another 67 - year - old man presented with pigmented lesion at his right heel. He also had popliteal node metastasis detected on the MRI. They underwent wide excision of the primary lesion with popliteal node dissection. Results: In the first case, $2.5{\times}2.5cm$ sized metastatic melanoma in popliteal node was pathologically confirmed. There were no postoperative complications, and to date(18 months after the surgery), the patient is alive with no evidence of disease. In the second case, multiple(4) metastatic melanoma in popliteal nodes was confirmed. The patient is alive, but has had interferon therapy for liver metastasis. Conclusion: By increasing the use of lymphoscintigraphy or PET as a preoperative diagnostic work - up for metastasis, even popliteal node metastasis undetectable in a physical exam becomes detectable. When metastatic lymph node is found, node dissection is the standard of care. Therefore, it is essential that we know the anatomy and surgical technique for popliteal lymph node dissection.

• 한국정보통신학회:학술대회논문집
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• 한국정보통신학회 2014년도 춘계학술대회
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• pp.781-783
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• 2014

유동성을 가진 노드들로 구성된 모바일 애드 혹 네트워크(Mobile Ad hoc Network)는 토폴로지의 변화에 따른 오버헤드를 발생한다. 오버헤드를 줄이기 위해, 클러스터를 형성하여 클러스터 헤드노드를 통해 통신하는 계층적 네트워크연구가 진행되어 왔다. 클러스터 헤드노드가 트래픽의 집중에 의해 트래픽이 증가하면, 클러스터 멤버노드는 목적지 노드에게 메시지를 전달하지 못하는 상황이 발생한다. 이를 해결하기 위해 본 논문에서는 Step Parent 알고리즘을 제안한다. 본 논문에서 제안하는 알고리즘은 클러스터 멤버노드는 통신 반경 안에 있는 클러스터 헤드노드들의 경로를 통해, 클러스터 멤버노드가 속한 클러스터 헤드노드의 트래픽을 파악한다. 클러스터 헤드노드가 트래픽이 집중되어 있을 경우, 클러스터 멤버노드는 타 클러스터 헤드노드의 경로 정보를 이용하여, 새로운 라우팅 경로를 생성하고 메시지를 전달함으로써, 네트워크 전달성이 증가한다.

• 제어로봇시스템학회논문지
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• 제19권3호
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• pp.268-274
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• 2013

In this paper, the performance analysis of optics-based sensor node localization using ToF (Time of Flight) scheme is conducted. Generally, the position of the sensor node is calculated on the base station. And the base station scans neighboring sensor nodes with a laser. The laser which is reflected from one sensor node, however, can be reached to the base station at different angles according to the scanning resolution. This means that the error of the reached angle can increase and one node may be recognized as different nodes. Also the power of laser can decrease because the laser signal spread. Thus the sensor node which is located at a long distance from the base station cannot be detected. In order to overcome these problems which can be occurred in localization using ToF, the beam spot, the scanning resolution, the size of reflector and the power of laser at the sensor node were analyzed. It can be expected that the consequence of analysis can be provided in acquisition of accurate position of sensor node and construction of optics-based sensor node localization system.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제14권9호
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• pp.3615-3638
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• 2020

Node identity authentication is an essential means to ensure the security of the Internet of Things. Existing blockchain-based IoT node authentication schemes have many problems. A heterogeneous IoT node authentication scheme based on an improved hybrid blockchain is proposed. Firstly, the hybrid blockchain model is designed to make the blockchain and IoT environment more compatible. Then the proxy node selection mechanism is intended to establish a bridge between the ordinary IoT node and the blockchain, building by calculating the trust value between nodes. Finally, based on the improved hybrid blockchain, the node authentication scheme of the model and proxy node selection mechanism establishes a secure connection for communication between nodes. Safety and performance analysis shows proper safety and performance.

• International Journal of Internet, Broadcasting and Communication
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• 제12권3호
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• pp.156-162
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• 2020

Wireless Sensor Network (WSN) field is mainly studied to monitor and characterize large-scale physical environments to track various environmental or physical conditions, such as temperature, pressure, wind speed and humidity. WSN can be used in various applications such as wild surveillance, military target tracking and monitoring, dangerous environmental exploration and natural disaster relief. We design probabilistic mobile models that apply to mobile ad hoc network mobile environments. A probabilistic shift model proposed by dividing the number of moving nodes and the distance of travel into two categories to express node movement characteristics. The proposed model of movement through simulation was compared with the existing random movement model, ensuring that the width and variation rate of the first node node node node (FND) was stable regardless of the node movement rate. In addition, when the proposed mobile model is applied to the routing protocol, the superiority of network life can be verified from measured FND values. We overcame the limitations of the existing random movement model, showing excellent characteristics in terms of energy efficiency and stable in terms of changes in node movement.

• Applied Microscopy
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• 제20권1호
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• pp.77-89
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• 1990

The ultrastructures of the hemal node and the hemolymph node in the Korean native goat were observed by transmission and scanning elelctron microscopies for their morphological features. The sinus of hemal node was lined by endothelial-like reticular cells that had an euchromatin-rich nucleus and many cytoplasmic processes by which reticular fibers were surrounded. In the hemolymph node, the mast cell and the plasma cell were closely contact each other by the cytoplasmic process. The hemal node had venous sinusal-like vessels which were different from the deep sinus, and the hemolymph node had lymph capillaries. The lymph vessels with valves were observed in the capsule of the hemolymph node.

• 대한두경부종양학회지
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• 제34권1호
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• pp.1-7
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• 2018

Papillary thyroid carcinoma has a good prognosis, but the frequency of locoregional lymph node metastasis is high and is known to occur stepwise fashion. Prophylactic central node dissection in papillary thyroid carcinoma is widely performed from the past. But, the pros and cons of the prophylactic central node dissection has been ongoing for a long time. In the American Thyroid Association management guideline for thyroid nodules and differentiated thyroid cancer, which is the most widely used, recommendations about prophylactic central node dissection has been changed in past ten years. In recent systematic review and meta-analysis, prophylactic central node dissection increases the rate of transient hypocalcemia and recurrent laryngeal nerve injury, but there is no difference in the frequency of permanent hypocalcemia or recurrent laryngeal nerve injury. Prophylactic central node dissection has not been shown to improve patient survival, but recurrence has been reported to decrease. According to a questionnaire survey of the members of Korean Scociety of Thyroid-Head and Neck Surgery, Korean doctors tend to perform the prophylactic central node dissection more aggressively than other countries. The reason for this is that Korea has a large number of thyroid surgeries and therefore surgeons are more experienced than other countries.

• 한국통신학회논문지
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• 제13권1호
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• pp.63-73
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• 1988

본 논문에서는 확률적 방향성 그래프에서 시점(source node)과 종점(terminal node) 간의 통신할 수 있는 확률인 단점간 신뢰도를 계정하는 알고리즘을 제시하였다. Satyanarayana의 factoring $theorem^{(7)}$을 이용하여 확률적 방향성 그래프에서 시점에 연결되어 있는 에지(edge)를 개방(open)과 단락(short)상태로 감축하여 원래의 그래프를 2개의 감축된 그래프로 분리한 후, 본 논문이 제시한 에지제거법과 일반적인 직, 병렬 감축법을 분리된 그래프에 적용한다. 이 에지 감축(edge reduction)을 source node와 terminal node가 단일 에지로 연결될때까지 반복한다. 또한 복잡하고 규모가 큰 망에 대한 단점간 신뢰도를 계정하기 위해서 전산기 프로그램을 제시하였다.