• Title/Summary/Keyword: NO release

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Correlation between Fluoride Release, Microhardness and Solubility of High viscosity Glass Ionomers (고점도 글라스아이오노머의 불소 유리량, 미세경도 및 용해도의 상관관계)

  • Shin, Bisol;Kim, Jongsoo;Yoo, Seunghoon
    • Journal of the korean academy of Pediatric Dentistry
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    • v.45 no.4
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    • pp.418-425
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    • 2018
  • This study was to measure and compare the amount of fluoride, microhardness and solubility of high viscosity glass ionomer and resin-reinforced glass ionomer during 84 days. Fuji IX GP EXTRA, Fuji IX GP, Fuji II LC and Filtek$^{TM}$ Z350XT stored in deionized water for 84 days to measure fluoride release, microhardness and solubility. As a result of measurement of fluoride release, all the glass ionomers showed the highest amount of fluoride release on day 1 and gradually decreased. Fuji IX GP EXTRA showed the highest amount of fluoride release and cumulative release. And Fuji IX GP and Fuji II LC showed no significant difference. Microhardness measurements showed that all experimental groups decreased 1 day after exposure to water. After 84 days, microhardness showed no significant difference between Fuji IX GP EXTRA and Fuji IX GP, and Fuji II LC was the lowest. In the solubility measurement, Fuji IX GP EXTRA, Fuji IX GP, and Fuji II LC increased rapidly to 21 days. After 21 days, there was no significant difference in the three groups. As a result, short term fluoride release affects solubility and microhardness, but long term fluoride release has no correlation. Through this study, the amount of fluoride, microhardness, and solubility of various glass ionomers were evaluated, and these properties could be applied clinically.

Arthroscopic Capsular Release for Painful Throwing Shoulder With Posterior Capsular Tightness

  • Yoneda, Minoru;Nakagawa, Shigeto;Mizuno, Naoko;Fukushima, Sunao;Hayashida, Kenji;Mae, Tatsuo;Izawa, Kazutaka
    • 대한관절경학회:학술대회논문집
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    • 2006.11a
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    • pp.35-39
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    • 2006
  • Posterior capsular tightness with glenohumeral internal rotation deficit is usually considered to be an acquired condition of the throwing shoulder and is usually treated conservatively. However, because posterior capsular tightness is sometimes irreversible, we have performed arthroscopic capsular release for painful throwing shoulder with posterior capsular tightness. The true loss of internal rotation and posterior stiffness was confirmed by examination with the patient under anesthesia, and contracture of the posterior capsule and the posterior band of the inferior glenohumeral ligamant was observed arthroscopically. Because an extensive adhesion between the capsule and the fascia of the external rotators was noted, a capsular release was performed from 6 o'clock to 11 o'clock (in the right shoulder) to completely expose the muscle belly of the external rotators. Of the first 16 consecutive patients, 4 had no concomitant lesions and underwent posterior capsular release alone. With a minimum of 2 years' follow-up, it was ascertained that the throwing pain completely disappeared in 14 patients and improved in 2. In all, 11 patients returned to their preinjury performance level, and 5 returned to a lower level of function. In the 4 patients who had no concomitant lesions, throwing pain completely disappeared, and all were able to return to their preinjury performance level.

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A Comparison of Myofascial Release and Ultrasound in Patients with Myofascial Pain Syndrome on Neck (경부근막동통증후군 환자에게 근막이완요법과 초음파치료의 비교)

  • Kim, Jong-Woo;Hyun, Sang-Wook;Seo, Hyun-Kyu
    • The Journal of Korean Academy of Orthopedic Manual Physical Therapy
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    • v.15 no.2
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    • pp.15-24
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    • 2009
  • Objectives : The purpose of this study is to compare the effectiveness between myofascial release technique and ultrasound in subjects with myofascial pain syndrome. Method : Twenty subjects with myofascial pain syndrome were randomly assigned to a myofascial release technique group(n=10) or an ultrsound group(n=10). The Cervical Range of Motion(C-ROM) instrument was used to measure cervical range of motion. Electromyography(EMG) was used to measure muscle power sternocleidomastoid and upper trapezius. Result : The result of this study shows there were no significant differences in ROM increase and muscle power increase between the myofascial release technique group and the ultrasound group. In the group with Myofascial Release Technique, the average score was $61.40{\pm}11.12$ in SCM flexion of C-ROM and $127.87{\pm}4.24$ in Rt. upper trapezius extension of EMG. In the group with ultra sound, the average score was $68.60{\pm}10.02$ in SCM flexion of C-ROM and $131.50{\pm}5.45$ in Rt. upper trapezius extension of EMG. Conclusion : The results suggest that there was no significant difference between two therapeutic techniques.

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Sustained Drug Release of Polyamide Microcapsules (Polyamide Microcapsule의 성질과 서방성)

  • 김계용;김진홍
    • Journal of Biomedical Engineering Research
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    • v.8 no.2
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    • pp.135-144
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    • 1987
  • Polyamide microcapsules were designed for a sustained drug release. As a model, riboflavin was e no apsulated in polyamide microcapsules. Polyamide microcapsules were prepared from thiamines and acid bichlorides by the interfacial polycondensation reaction. The diamines used in ttlis works were ethylenediamine and 1, 6-hexamethylenediamine. Sebacoylchloride and teruphthaloylchloride were employed as acid bichlorides. The following parameters were studied; the release of several kinds of polyamide microcapsules , the various concentrations of diamines and acid dichlorides ; the various concentrations of surfactants : the various pH range of sink solution during the dissolution test. The release amount of riboflavin from aromatic polyamide micrcapsule was higher than that of aliphatic polyamide microcapsule The release rate of riboflavin from the polyamide microcapsule was decreased with increase of concentration of thiamines, arid dichlorides and surfactants which is used for preparing polyamide microcapsule. Release riboflavin from polyamide microcapsule was lower at pH 7 than pH 2 in sink-solution for dissolution test.

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Attitudinal Factors Related to Release for Adoption among Teen-age Unwed Mothers (10대 미혼모의 유아입양 관련요인들에 관한 연구)

  • Yoon, Mi Hyun;Lee, Jae Yeon
    • Korean Journal of Child Studies
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    • v.22 no.1
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    • pp.67-82
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    • 2001
  • The attitudes toward release for adoption of 130 teen-age unwed korean mothers were studied with the use of the donnelly and Voydanoff(1991) scale of attitudes about release for adoption and expectations regarding parenthood. Data were analyzed by t-test. While there were no socio-demographic differences between the 10.7% of mothers who planned on keeping their babies and the 89.3% who planned on release for adoption, the group choosing release for adoption thought they didn't have the ability to rear their babies and they took a negative attitude toward pregnancy compared with the group choosing to keep their babies. The group opting for release for adoption supposed that child rearing will interfere with their education, and they have a negative attitude about child rearing in general.

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Dissoultion and Rectal Absorption of Acetaminophen from Suppositories (아세트아미노펜 좌제의 용출과 직장흡수)

  • 한정선;심창구;김신근
    • YAKHAK HOEJI
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    • v.31 no.5
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    • pp.286-295
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    • 1987
  • The relationship between in vitro release and in vivo bioavailability of acetaminophen from suppositories was investigated. Effect of glycyrrhizin on the drug release and rectal absorption in rats was also examined. Suppositories containing 25mg of acetaminophen were prepared with Wecobee FS (fatty base) or PEG (water-soluble base) bases. The release from the suppositories were determined with USP rotating basket dissolution apparatus and with the suppository release tester. The temperature of the dissolution medium was very critical for the dissolution of acetaminophen from Wecobee FS suppositories. The bioavailability of acetaminophen was calculated from the plasma concentration-time curve after rectal administration of the suppositories to the rats. There were no significant differences in AUC following rectal administration of Wecobee FS and PEG suppositories, but the release and absorption from the Wecobee FS suppositories were faster than those from PEG suppositories. The dissolution rate obtained by the suppository release tester was better correlated with in vivo absorption rate constant than that by the USP dissolution apparatus. It suggests that the partitioning between rectal fluid and suppository base is the rate-limiting step in the rectal absorption of acetaminophen from suppositories. Glycyrrhizin was found not to affect in vitro dissolution and rectal absorption of acetaminophen.

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Phosphorus Release from Sediment in Lake Sihwa and its Control

  • Kang, Seon Hong
    • Journal of Korean Society on Water Environment
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    • v.18 no.2
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    • pp.213-220
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    • 2002
  • In this study the effects of initial pH, temperature, dissolved oxygen concentration, and sediment depth on the release of phosphorus from sediment in Lake Sihwa were investigated. No phosphorus release occurred at $10^{\circ}C$ for all pH values. DO concentrations were decreased and equilibrium was obtained 4-8 days after phosphorus release started. The DO concentrations were less than 1 mg/L. Sediment depth had little effect on phosphorus release rate. In order to control the released phosphorus, raw sludge and chalk were used. Results showed that a portion of phosphorus was removed by adsorption to chalk and raw sludge. About 90 % phosphorus removal was observed using sludge and calcinated chalk from the water sample in Lake Sihwa.

Release and Bioavailability of Naloxone Sustained-Release Implants (Naloxone의 Polyphosphazene 이식제제에 관한 연구)

  • Suh, Sung-Yun;Park, Joo-Ae;Kim, Kil-Soo
    • Journal of Pharmaceutical Investigation
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    • v.27 no.3
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    • pp.225-231
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    • 1997
  • For the effective administration of naloxone, we attempted to investigate the naloxone sustained-release implants. Using the biodegradable polymer, poly[(diethyl glutamate)-co-(ethyl glycinate)phosphazenes](PGGP), the implantable devices containing naloxone hydrochloride(NLX HCl) and naloxone base(NLX) were prepared. The release rates of NLX and NLX HCl were compared. Influences of NLX contents on release rates were examined. For pharmacokinetic studies, NLX and NLX HCl loaded devices were implanted subcutaneously in rabbits and then the plasma concentrations of NLX were determined by HPLC(ECD). NLX-containing devices were implanted with various doses and pharmacokinetic parameters according to dose were calculated. The relative bioavailabilities were evaluated and compared. Incorporation of NLX in the polymer leaded to a slow release. There were no differences of release rates based on drug contents. In pharmacokinetic parameters determined in 216 hours, NLX loaded devices resulted in enhanced bioavailability with the higher AUC (p<0.01) than NLX HCl loaded devices and MRT was significantly (p<0.05) increased. This result demonstrates that NLX is more suitable for sustained release devices than NLX HCl. Therefore it is anticipated that the effective concentrations of naloxone could be maintained for longer periods and bioavailabilities could be improved by naloxone sustained-release implants, with varying drug base/hydrochloride.

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A Study on Combustion of Living Leaves for Various Coniferous Trees and Broadleaf Trees in Youngdong Areas (영동지역 주요 침엽수종 및 활엽수종 생엽의 연소특성에 관한 연구)

  • Lee, Hae-Pyeong;Lee, Si-Young;Park, Young-Ju
    • Journal of the Korean Society of Safety
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    • v.24 no.4
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    • pp.96-103
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    • 2009
  • This study was fulfilled to investigate the forest fire risk of forest fuels based on the combustion characteristics of living leaves of coniferous trees and broadleaf trees naturally growing in Youngdong areas of Gangwon Province by using cone calorimeter and smoke density chamber. According to the result, Pinus densiflora and Pinus rigida among coniferous trees released a greater amount of heat release than other kinds. The total smoke release varied depending on the species, whereas Pinus koraiensis showed the largest amount of smoke release. With regard to maximum smoke density, it was much higher in coniferous trees than in broadleaf trees. With regard to smoke temperature, Pinus densiflora showed the lowest compared to other kinds up until 200s from the ignition, but all most trees uniformly maintained constant temperature of about $70^{\circ}C$ after 200s. The concentrations of CO and $CO_2$ release were drastically increased at about 150s and then gradually decreased thereafter. Pinus densiflora showed a bit higher CO release than broadleaf trees, but there was no distinct difference in $CO_2$ release among tress.

Nitric oxide-Releasing Chitosan Nanoparticles; A Potential Impeding Strategy Against Salinity Stress in Arabidopsis thaliana

  • Waqas Rahim;Anjali Pande;Nusrat Jahan Methela;Da-Sol Lee;Bong-Gyu Mun;Hak-Yoon Kim;Byung-Wook Yun
    • Proceedings of the Korean Society of Crop Science Conference
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    • 2022.10a
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    • pp.157-157
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    • 2022
  • Plants being sessile are prone to various abiotic challenges, including salinity. Plants generally cope with salt stress by regulating their endogenous NO levels. NO exogenously applied in various forms also successfully impedes the salt stress, but its small size, short half life, and high volatility rate hamper its application in agriculture. NO application via CS as a nanocarrier is an alternate option to ensure the optimal kinetic release of NO for a long period compared to the free NO form. Herein, we synthesized and characterized GSNO-CS NP by ionic gelation of TPP with CS and then reacting with GSH, followed by reaction with NaNO2 suspension. The synthesized NPs were characterized using non-destructive analytical techniques such as DLS, FTIR, and SEM to ensure their synthesis and surface morphology. NO-release profile confirmed optimal kinetic NO release for 24 h from NO-CS NP as compared to free NO form. The efficiency of NO-CS NP was checked on Arabidopsis plants under salinity stress by gauging the morphological, physiological, and enzymatic antioxidant system and SOS pathway gene expression levels. Overall, the results revealed that NO-CS NP successfully mitigates salinity stress compared to free GSNO. Concluding, the findings provide sufficient experimental evidence for the application of nanotechnology to enhance NO delivery, thus inducing more benefits for the plants under stress conditions by mitigating the deleterious impacts of salt stress on the morphological and physiological status of the plants, and regulating the ions exchange by overexpression of SOS pathway candidate genes.

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