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Prognostic Factors on Overall Survival in Lymph Node Negative Gastric Cancer Patients Who Underwent Curative Resection

  • Jeong, Ji Yun;Kim, Min Gyu;Ha, Tae Kyung;Kwon, Sung Joon
    • Journal of Gastric Cancer
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    • v.12 no.4
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    • pp.210-216
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    • 2012
  • Purpose: To assess independent prognostic factors for lymph node-negative metastatic gastric cancer patients following curative resection is valuable for more effective follow-up strategies. Materials and Methods: Among 1,874 gastric cancer patients who received curative resection, 967 patients were lymph node-negative. Independent prognostic factors for overall survival in lymph node-negative gastric cancer patients grouped by tumor invasion depth (early gastric cancer versus advanced gastric cancer) were explored with univariate and multivariate analyses. Results: There was a significant difference in the distribution of recurrence pattern between lymph node-negative and lymph nodepositive group. In the lymph node-negative group, the recurrence pattern differed by the depth of tumor invasion. In univariate analysis for overall survival of the early gastric cancer group, age, macroscopic appearance, histologic type, venous invasion, lymphatic invasion, and carcinoembryonic antigen level were significant prognostic factors. Multivariate analysis for these factors showed that venous invasion (hazard ratio, 6.695), age (${\geq}59$, hazard ratio, 2.882), and carcinoembryonic antigen level (${\geq}5$ ng/dl, hazard ratio, 3.938) were significant prognostic factors. Multivariate analysis of advanced gastric cancer group showed that depth of tumor invasion (T2 versus T3, hazard ratio, 2.809), and age (hazard ratio, 2.319) were prognostic factors on overall survival. Conclusions: Based on our results, independent prognostic factors such as venous permeation, carcinoembryonic antigen level, and age, depth of tumor invasion on overall survival were different between early gastric cancer and advanced gastric cancer group in lymph node-negative gastric cancer patients. Therefore, we are confident that our results will contribute to planning follow-up strategies.

The Influence of Ego-resilience, Positive affect, Negative affect on military life stress in ROK air force soldiers (공군 병사의 자아탄력성, 정적 정서, 부적 정서가 군 생활 스트레스에 미치는 영향)

  • Kim, Eun-Shim;Kong, Jeong-Hyeon
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.15 no.4
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    • pp.2235-2243
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    • 2014
  • This study is the descriptive research tried in order to identify how the air force soldier's ego-resilience, positive affect, negative affect of air force soldiers on their military life stress. and a survey was conducted targeting 321 air force soldiers. The results of this study found that the subjects average scores in terms of ego-resilience, positive affect, negative affect, military life stress were 3.11, 3.16, 2.26 and 1.94 points, respectively. The factors of ego-resilience and positive affect showed significantly positive correlation, but the factors of negative affect and military life stress showed some negative correlation. The ego-resilience indirectly influence on the subjects' military life stress through the positive and the negative affect, not directly influenced on them. And the positive and the negative affects directly influenced on the subjects' military life stress. Therefore it needs to reduce soldiers' military life stress by developing a program to enhance soldiers' ego-resilience and to do more positive emotional experiences.

Vascular Invasion as an Independent Prognostic Factor in Lymph Node Negative Invasive Breast Cancer

  • Rezaianzadeh, Abbas;Talei, Abdolrasoul;Rajaeefard, Abdereza;Hasanzadeh, Jafar;Tabatabai, Hamidreza;Tahmasebi, Sedigheh;Mousavizadeh, Ali
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.11
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    • pp.5767-5772
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    • 2012
  • Introduction: Identification of simple and measurable prognostic factors is an important issue in treatment evaluation of breast cancer. The present study was conducted to evaluate the prognostic role of vascular invasion in lymph node negative breast cancer patients. Methods: in a retrospective design, we analyzed the recorded profiles of the 1,640 patients treated in the breast cancer department of Motahari clinic affiliated to Shiraz University of Medical Sciences, Shiraz, Iran, from January 1999 to December 2012. Overall and adjusted survivals were evaluated by the Cox proportional hazard model. All the hypotheses were considered two-sided and a p-value of 0.05 or less was considered as statistically significant. Results: Mean age in lymph node negative and positive patients was 50.0 and 49.8 respectively. In lymph node negative patients, the number of nodes, tumor size, lymphatic invasion, vascular invasion, progesterone receptor, and nuclear grade were significant predictors. In lymph node and lymphatic negative patients, vascular invasion also played a significant prognostic role in the survival which was not evident in lymph node negative patients with lymphatic invasion. Discussion: The results of our large cohort study, with long term follow up and using multivariate Cox proportional model and comparative design showed a significant prognostic role of vascular invasion in early breast cancer patients. Vascular invasion as an independent prognostic factor in lymph node negative invasive breast cancer.

A Study on Compensatory Consumption of Male and Female College Students (남녀 대학생의 보상소비성향에 관한 연구)

  • Yang, Se-Jeong;Lee, Eun-Hwa;Han, Sung-Hee
    • Journal of Families and Better Life
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    • v.26 no.1
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    • pp.1-14
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    • 2008
  • The purpose of this study was to investigate compensatory consumption propensity by male and female college students. The subjects of the study were 483 college students in Seoul, and SPSS 12.0 was used for statistical analysis. Two different types of compensatory consumption were considered separately positive compensatory consumption and negative compensatory consumption. The major findings were as follows. First, for male college students, drinking was the most preferable means of compensatory consumption to compensate for both negative and positive emotions. For female college students, their consumption patterns tended to include clothing purchase and eating-out for positive emotions and eating-out, reading and drinking for compensating negative emotions. Second, for both male and female students, the consumption propensity for compensating positive emotion was found to be higher than that for compensating negative emotion. And the consumption propensities for compensating positive and negative emotions were higher for female students when compared to those of male students. According to the results of regression analysis showing the relative effect of each variable to compensatory consumption, sex and consumption tendency were found to be relative variables on both positive and negative compensatory consumptions. Female students were found to be more likely to consume for compensating emotion than male students after other variables were controlled. For positive compensatory consumption, consumption propensity and materialism were found to be the most effective variables, and for negative compensatory consumption, materialism was the most effective variable.

Safety Performance Functions for Central Business Districts Using a Zero-Inflated Model (영과잉을 고려한 중심상업지구 교통사고모형 개발에 관한 연구)

  • Lee, Sang Hyuk;Woo, Yong Han
    • International Journal of Highway Engineering
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    • v.18 no.4
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    • pp.83-92
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    • 2016
  • PURPOSES : The purpose of this study was to develop safety performance functions (SPFs) that use zero-inflated negative binomial regression models for urban intersections in central business districts (CBDs), and to compare the statistical significance of developed models against that of regular negative binomial regression models. METHODS : To develop and analyze the SPFs of intersections in CBDs, data acquisition was conducted for dependent and independent variables in areas of study. We analyzed the SPFs using zero-inflated negative binomial regression model as well as regular negative binomial regression model. We then compared the results by analyzing the statistical significance of the models. RESULTS : SPFs were estimated for all accidents and injury accidents at intersections in CBDs in terms of variables such as AADT, Number of Lanes at Major Roads, Median Barriers, Right Turn with an Exclusive Turn Lane, Turning Guideline, and Front Signal. We also estimated the log-likelihood at convergence and the likelihood ratio of SPFs for comparing the zero-inflated model with the regular model. In he SPFs, estimated log-likelihood at convergence and the likelihood ratio of the zero-inflated model were at -836.736, 0.193 and -836.415, 0.195. Also estimated the log-likelihood at convergence and likelihood ratio of the regular model were at -843.547, 0.187 and -842.631, 0.189, respectively. These figures demonstrate that zero-inflated negative binomial regression models can better explain traffic accidents at intersections in CBDs. CONCLUSIONS : SPFs that use a zero-inflated negative binomial regression model demonstrate better statistical significance compared with those that use a regular negative binomial regression model.

The effect of customer incivility on emotional exhaustion through negative affectivity (고객 무례행동의 부정적 정서를 통한 감정소지에 미치는 영향)

  • Han, Su Jin;Choe, Min Seok
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.19 no.1
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    • pp.486-496
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    • 2018
  • Customer incivility is an important stress factor employees performing service tasks, and this is equally true for employees who perform civil affairs services. The purpose of this study is to investigate the negative effects of adverse customer behavior and ways to reduce it. This study adopts the Conservation of Resource (COR) theory in order to examine customer incivility. This study predicts that customer incivility will negative emotions and eventually lead to emotional exhaustion in employees. We also predict that social support (organizational support, supervisor support, coworker support) perceived by employees would moderate the relationship between customer incivility and negative emotions. This study is based on 481 questionnaires collected from public officials. The results are as follows: First, customer incivility causes negative emotions. Second, negative emotions mediate the relationship between customer incivility and emotional exhaustion. Third, the relationship between customer incivility and negative emotions showed moderating effects on the perception of organizational support which is one of three types of social support. Based on the results of this study, implications, limitations, and future direction of research are suggested.

The Effects of Maternal Negative Behaviors and Children's Attachment Stability on Children's Aggression (모의 부정적 양육행동과 아동의 모애착안정성이 아동의 공격성에 미치는 영향)

  • Jun, Joo-Ram;Kim, Soon-Ok
    • Journal of Families and Better Life
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    • v.27 no.2
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    • pp.173-189
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    • 2009
  • The purpose of this study was to find and provide the prevention method by examining the Effects of Maternal Negative Behaviors and Children's Attachment Stability on Children's Aggression. The subjects were 339 children of fifth or sixth graders in Seoul. The questionnaires were derived and modified from Young Ae Park (1995) for the maternal negative behavior, Children's attachment stability from Ok Jung (1998) and Children's aggression from In Sun Jung(2006). The date were analyzed with descriptive statistics, t-test, F-test, Pearson's correlations and hierarchical multiple regression by SPSS 14.0 program. The major findings were as follows : First, the result showed there was average level of negative relationship when mother's negative behavior was compared with children's attachment whereas it showed average level of positive relationship in aggression. And also, low level of negative relationship showed between the attachment and aggression. Second, studying the influence it gives to the children's reaction and aggression after adding the children, parent and the family's popular social variables into the maternal's negative behavior, the outcomes showed the maternal's discipline and defiance upbringing had influenced the highest and tolerance, negligence was second high. This study mainly looked at the relationship between the maternal negative behavior with the children's attachment and aggression, but not like the nations pre.studied results, changes in human relation were examined with identifying the main several factors that bring greatest influence to the children's attachment and aggression. In conclusion, the children's attachment and aggression's the cause of the children's attachment and aggression were mainly from the maternal discipline and defiance upbringing. Based on this conclusion, it is essential for the maternal to have a sound discipline with right minds for endeavor to bring up the children with bring minds with less aggression and composed attachment.

The Acquisition of Negatives in Five Korean Children (한국 아동의 부정사 획득)

  • Yi, Soon Hyung
    • Korean Journal of Child Studies
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    • v.6 no.1
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    • pp.17-40
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    • 1985
  • This study investigated Korean children's early acquisition of negatives and focused on four research questions: 1) processing of negative variations; 2) the nature of negatives when negatives are completely acquired in Korean (in which meaning and form are matched in one to one mapping); 3) the validity of Bellugi's negative acquisition model in Korean; and 4) the cause of child's erroneous sentence production: limited ability or regularity in children's cognition. The language data of the five subjects (age span; 1.1 - 3.11) were collected by their parents in the natural setting of the home. The results showed that 1) the pivot form, was processed in many ways from a simple to a complicated form, such as <(X+X')+N> <(x+x')+N,Y> <(x+x') N,(y+y')>. It appeared that the children used a simple negative format to reach a one-step advanced negative format. 2) Korean negatives are divided into range of negation in the negative sentence (part or whole), strength of negation (absolute or general), functions of meaning (negation, absences, refusal, prohibition, impossibility). All five children acquired negative sentences in all functions and the complete range after 3 years of age. 3) In spite of the differences in age level, Bellugi's four stage model was in evidence; that is, Korean children's negative acquisition was almost identical with Bellugi's tour stage model in deep structure. 4) Analyses of children's error sentences showed that the sentences with errors were made not because of the children's limitation in cognitive ability but because of the strict application of regularity of rules from the original grammars. Consequently, the children produced negative sentences using two rules: the rule of additive complexity (from simple to complex) and the rule of division (from one to several).

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The Influence of Negative Emotions on Customer Contribution to Organizational Innovation in an Online Brand Community (온라인 브랜드 커뮤니티 내 부정적 감정들이 기업 혁신을 위한 고객 기여에 미치는 영향)

  • Jung, Suyeon;Lee, Hanjun;Suh, Yongmoo
    • Journal of Internet Computing and Services
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    • v.14 no.4
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    • pp.91-100
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    • 2013
  • In recent years, online brand communities, whereby firms and customers interact freely, are emerging trend, because customers' opinions collected in these communities can help firms to achieve their innovation effectively. In this study, we examined whether customer opinions containing negative emotions have influence on their adoption for organizational innovation. To that end, we firstly classified negative emotions into five categories of detailed negative emotions such as Fear, Anger, Shame, Sadness, and Frustration. Then, we developed a lexicon for each category of negative emotions, using WordNet and SentiWordNet. From 81,543 customer opinions collected from MyStarbucksIdea.com which is Starbucks' brand community, we extracted terms that belong to each lexicon. We conducted an experiment to examine whether the existence, frequency and strength of terms with negative emotions in each category affect the adoption of customer opinions for organizational innovation. In the experiment, we statistically verified that there is a positive relationship between customer ideas containing negative emotions and their adoption for innovation. Especially, Frustration and Sadness out of the five emotions are significantly influential to organizational innovation.

Evaluation of Negative Results of BacT/Alert 3D Automated Blood Culture System

  • Kocoglu M. Esra;Bayram Aysen;Balcl Iclal
    • Journal of Microbiology
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    • v.43 no.3
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    • pp.257-259
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    • 2005
  • Although automated continuous-monitoring blood culture systems are both rapid and sensitive, false-positive and false-negative results still occur. The objective of this study, then, was to evaluate negative results occurring with BacT/Alert 3D blood culture systems. A total of 1032 samples were cultured with the BacT/Alert 3D automated blood culture system, using both aerobic (BPA) and anaerobic (BPN) media, and 128 of these samples yielded positive results. A total of 904 negative blood samples were then subcultured in $5\%$ sheep blood agar, eosin methylene blue, chocolate agar, and sabouraud-dextrose agar. Organisms growing on these subcultures were subsequently identified using both Vitek32 (bioMerieux, Durham, NC) and conventional methods. Twenty four $(2.6\%)$ of the 904 subcultures grew on the subculture media. The majority $(83.3\%)$ of these were determined to be gram-positive microorganisms. Fourteen $(58.3\%)$ were coagulase-negative staphylococci, two $(8.3\%)$ were Bacillus spp., one $(4.2\%)$ was Staphylococcus aureus, and one $(4.2\%)$ was identified as Enterococcus faecium. Streptococcus pneumoniae and Neisseria spp. were isolated together in two $(8.3\%)$ vials. Gram-negative microorganisms comprised $12.5\%$ of the subcultures, of which two $(8.3\%)$ were found to be Pseudomonas aeruginosa, and one $(4.2\%)$ was Pseudomonas fluorescens. The other isolate $(4.2\%)$ was identified as Candida albicans. We conclude that the subculture of negative results is valuable in the BacT/Alert 3D system, especially in situations in which only one set of blood cultures is taken.