• Proceedings of the Korean Institute of Communication Sciences Conference
• /
• 2004.11a
• /
• pp.5-5
• /
• 2004

• Proceedings of the Korean Institute of Communication Sciences Conference
• /
• 2004.11a
• /
• pp.399-399
• /
• 2004

• Proceedings of the Korea Information Processing Society Conference
• /
• 2004.05a
• /
• pp.1421-1424
• /
• 2004

본 논문은 IPv6의 보급확산을 위해서 추진된 NCA의 IPv6 웹 포탈사이트 구축을 통해 정의된 시스템 아키텍처를 소개하며, S/W, 네트워크, 하드웨어의 실질적인 구축 사례를 제시한다. 그리고, 이와 같은 웹 서비스 제공을 통해 일반 이용자를 IPv4에서 IPv6로 유도할 수 있는 효과적인 서비스 정책과 시스템 구현 기술을 보여준다.

• YAKHAK HOEJI
• /
• v.59 no.3
• /
• pp.92-97
• /
• 2015

KIOM-MA128 is a novel Korean herbal medicine with anti-atopic, anti-inflammatory and anti-asthmatic effects. This article presents the first pharmacokinetic study on KIOM-MA128. The purpose of this study was to characterize a pharmacokinetic characteristic of matrine, a potential marker of KIOM-MA128, in rats using population pharmacokinetic model. 1, 2 and 8 g/kg of KIOM-MA128 were administered to rats orally and plasma concentrations of matrine was determined by HPLC-MS/MS. Non-compartmental analysis (NCA) was performed using Phoenix$^{(R)}$ and pharmacokinetic model was built using NONMEM$^{(R)}$. This model was validated with internal validation which is visual predictive check (VPC) and bootstrap. The NCA result of matrine showed that $C_{max}$ was 294.24, 552.22 and 868.65 ng/ml, $AUC_{inf}$ was 1273.05, 2724.76 and $9743.25ng{\cdot}hr/ml$ and $T_{max}$ was 1, 1.3 and 2.3 hr for the doses of 1, 2, and 8 g/kg, respectively. The rat plasma concentrations were described very well with one-compartment model. Pharmacokinetic model for matrine was successfully developed and evaluated. Finally, our model is helpful to understand pharmacokinetic characteristic of KIOM-MA128.

• Journal of Radiopharmaceuticals and Molecular Probes
• /
• v.2 no.2
• /
• pp.84-95
• /
• 2016

Considerably increasing interest in using the theranostic isotopes/ isotope pairs of radiometals like $^{44/47}Sc$ and $^{64/67}Cu$ for diagnosis and/or therapeutic applications in the nuclear medicine procedures necessitates its reliable production and supply. Separation and purification of no-carrier-added (NCA) isotopes from macro quantitates of the irradiated target matrix along with other impurities is a cardinal procedure amongst several other steps involved in its production. Multitudinous methods including but not limited to liquid-liquid (solvent) extraction, extraction chromatography (EXC), ion exchange, electrodeposition and sublimation are routinely applied either solitarily or in combination for the separation and purification of radioisotopes depending on their production routes, radioisotope of interest and impurities involved. However, application of EXC though has shown promises towards the numerous separation techniques have not received much attention as far as its application prospects in the field of nuclear medicine are concerned. Advances in the recent past for application of the EXC resins in separation and purification of the several medically important radioisotopes at ultra-high purity have shown promising behavior with respect to their operation simplicity, acidic and radiolytic stability, separation efficiencies and speedy procedures with the enhanced and excellent extraction abilities. In this mini review we will be talking about the recent developments in the application and the use of EXC techniques for the separation and purification of $^{44/47}Sc$ and $^{64/67}Cu$ for medical applications. Furthermore, we will also discuss the scientific and practical aspects of EXC in the view of separation of the NCA trace amount of radionuclides.

• Journal of KIISE:Software and Applications
• /
• v.26 no.10
• /
• pp.1156-1166
• /
• 1999

의사결정 시스템은 전사적인 의사결정과 전략적 정보수집을 위해 거대한 량의 정보를 빠른 시간내에 제공할 것을 요구한다. 데이타 웨어하우스는 이러한 정보를 신속히 제공하기 위해 여러 지역 데이타베이스로부터 필요한 정보를 사전에 추출하고 가공 및 통합하여 별도의 저장공간에 저장한다. 일반적으로, 웨어하우스 내의 정보는 지역 데이타베이스에 저장된 정보에 대한 실체화된 뷰로서 간주하며 지역 데이타의 변경에 따라 일관성을 유지하도록 반영해야 한다. 본 논문에서는 일관성을 유지하기 위해 정보 공유가 가능한 데이타 웨어하우스 시스템의 구조와 비-보상 실체 뷰 관리 기법을 제안한다. 본 논문에서 제안한 데이타 웨어하우스 시스템의 구조는 지역 데이타베이스에서 추출된 정보를 관리하는 별도의 지역 정보 관리자를 두어 뷰 관리자들 간의 정보 공유가 가능하게 한다. 비-보상 실체 뷰 관리 기법은 지역 데이타 변경 사건에 따른 뷰 관리 시 다른 사건에 의해 영향을 받지 않도록 하기 때문에 기본의 사전 보상이나 나중 보상 기법과는 달리 추가적인 질의 처리를 요구하지 않는 기법이다.Abstract A decision support system(DSS) commonly requires fast access to tremendous volume of information. A data warehouse is a database storing the information that is extracted, filtered and integrated from several relevant local databases to reply upon aggregated queries. The information stored in the data warehouse can be regarded as materialized views. The materialized view has to be modified according to the change of the corresponding local databases to preserve the data consistency. In this paper, we propose a data warehousing system architecture allowing information sharing (DAWINS), and a non-compensating materialized view maintenance algorithm(NCA). DAWINS architecture allows relevant information to be shared by individual view managers with local data manager for each local database. Unlikely to the pre- or post-compensating algorithms, which are required to remove the effects of some events to other view in the process of view maintenance, NCA does not require any additional query processing, since a local data manager in DAWINS already maintains the effects of update events occurring in local systems.

• Journal of the Korean Recycled Construction Resources Institute
• /
• v.2 no.2
• /
• pp.107-114
• /
• 2014

The objective of this study is to evaluate the strength development of blast furnace slag concrete in response to the use of recycled aggregate as alkali activator. The influence of the amount of recycled aggregate was evaluated depending on different ratios of replacement for each RFA and RCA to NFA and NCA, respectively. The results indicated that as replacement of RFA and RCA increased, their strength exhibited to be increased. This was due to the fact that the latent hydraulic properties of blast furnace slag was activated by the alkali in recycled aggregates. However, in case of 365-days, it showed lower compressive strength than using NA(natural aggregates) which could be explained as the exhaustively use of alkali containing in RA. The specimens using RA showed about 90% of compressive strength comparing with specimens using NA.

• Information Systems Review
• /
• v.4 no.2
• /
• pp.95-109
• /
• 2002

The purpose of this research is to investigate a way to increase interoperability between information systems. We proposed a technical reference model (TRM) and a standard profile (SP) that are components of ITA as tools to secure information system interoperability. First, we composed TRM by choosing technology field that need standardization for information system interoperability. And, we choose standards to apply in each technology field of TRM as a interoperability common SP.

• Information Systems Review
• /
• v.6 no.2
• /
• pp.1-24
• /
• 2004

This paper develops a framework for analyzing the effectiveness of broadband network from the value chain view. The value chain of broadband network is composed of activities such as broadband network building, application/equipments development, information systems utilization. The effectiveness from the interaction between these activities are defined as the effectiveness of informatization(private and public sector) and the effectiveness of IT Industry(effects on production on inducement of broadband carriers, IT equipments and service market creation, online digital contents market creation). For testing its real-world applicability, a case study is performed on the broadband network of Korea and the effectiveness of the framework for analyzing the effectiveness of broadband network is demonstrated.

• Journal of the Korea institute for structural maintenance and inspection
• /
• v.22 no.6
• /
• pp.189-196
• /
• 2018

Degraded shear performance of reinforced concrete members with recycled coarse aggregate (RCA) compared to flexural strength is a problem. To address this, steel fibers can be used as concrete reinforcement material. In this study, the strength and deformation characteristics of SFRC beams using RCA were to be determined by shear tests. Major experimental variables include the volume fraction of steel fiber (0, 0.5%, 1%), the replacement rate of RCA (0%, 100%), and the shear span ratio (a/d = 1, 2). As a result of the experiment, the shear strength of the specimen increased as the rate of mixing steel fiber increased. For specimens with RCA and 1% steel fiber, the maximum shear strengths increased by 1.77 - 6.25% compared to specimens with normal coarse aggregate (NCA). On the other hand, at 0-0.5% steel fiber, the shear strengths of RCA specimens were reduced by 24.2% to 49.2% compared to NCA specimens. This indicates that reinforcement with 1% volume fraction of steel fiber greatly contributes to preventing shear strength reduction due to the use of RCA.