• ETRI Journal
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• v.43 no.5
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• pp.869-880
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• 2021

Herein, we estimate the direction of arrival (DOA) of non-Gaussian signals for nested arrays (NAs) by implementing the fourth-order difference co-array (FODC) and successive methods. In particular, considering the property of the fourth-order cumulant (FOC), we first construct the FODC of the NA, which can obtain O(N⁴) virtual elements using N physical sensors, whereas conventional FOC methods can only obtain O(N²) virtual elements. In addition, the closed-form expression of FODC is presented to verify the enhanced degrees of freedom (DOFs). Subsequently, we exploit the vectorized FOC (VFOC) matrix to match the FODC of the NA. Notably, the VFOC matrix is a single snapshot vector, and the initial DOA estimates can be obtained via the discrete Fourier transform method under the underdetermined correlation matrix condition, which utilizes the complete DOFs of the FODC. Finally, fine estimates are obtained through the spatial smoothing-Capon method with partial spectrum searching. Numerical simulation verifies the effectiveness and superiority of the proposed method.

• Journal of The Korean Society of Agricultural Engineers
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• v.63 no.5
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• pp.63-71
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• 2021

Windbreak forests, which have a windproof effect against strong winds, are known to be effective in reducing the spread of odors and dust emitted from livestock farms. The effect of reducing the spread of odors and dust can be estimated through numerical models such as computational fluid dynamics, which require aerodynamic coefficients of the windbreaks for accurate prediction of their performance. In this study, we aimed to evaluate the aerodynamic coefficients, Co, C₁, C₂, and α, of two windbreaks, Thuja occidentalis and a mesh net, through wind tunnel experiments. The aerodynamic coefficients were derived by the relation between the incoming wind speed and the pressure loss due to the windbreaks which was measured by differential pressure sensors. In order to estimate the change in the aerodynamic coefficient concerning various leaf density, the experiments were conducted repeatedly by removing the leaves gradually in various stages. The results showed that the power law regression model more suitable for coefficient evaluation compared to the Darcy-Forchheimer model.

• Korean Journal of Agricultural Science
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• v.46 no.1
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• pp.183-194
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• 2019

Adulteration of argan oil with some other cheaper oils with similar chemical compositions has resulted in increasing demands for authenticity assurance and quality control. Fast and simple analytical techniques are thus needed for authenticity analysis of high-priced argan oil. Raman spectroscopy is a potent technique and has been extensively used for quality control and safety determination for food products In this study, Raman spectroscopy in combination with a net analyte signal (NAS)-based methodology, i.e., hybrid linear analysis method developed by Goicoechea and Olivieri in 1999 (HLA/GO), was used to predict the different concentrations of olive oil (0 - 20%) added to argan oil. Raman spectra of 90 samples were collected in a spectral range of $400-400cm^{-1}$, and calibration and validation sets were designed to evaluate the performance of the multivariate method. The results revealed a high coefficient of determination ($R^2$) value of 0.98 and a low root-mean-square error (RMSE) value of 0.41% for the calibration set, and an $R^2$ of 0.97 and RMSE of 0.36% for the validation set. Additionally, the figures of merit such as sensitivity, selectivity, limit of detection, and limit of quantification were used for further validation. The high $R^2$ and low RMSE values validate the detection ability and accuracy of the developed method and demonstrate its potential for quantitative determination of oil adulteration.

• Mycobiology
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• v.47 no.2
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• pp.256-260
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• 2019

Neuraminidase (NA) cleaves the glycosidic bond linkages of sialic acids to release the mature virions from infected cells and has been an attractive therapeutic target for anti-influenza agents. In our ongoing investigation of NA inhibitors in mushroom extracts, we found that the extract the fruiting body of Glaziella splendens potently inhibited neuraminidase. The fruiting bodies of G. splendens were extracted and partitioned successively with hexane, ethyl acetate, and butanol. The ethyl acetate soluble-layer was subjected to silica gel and Sephadex LH-20 column chromatographies, and MPLC to obtain five compounds (1-5). Their structures were determined by spectroscopic methods. NA inhibitory activity of these compounds was evaluated using NAs from recombinant rvH1N1, H3N2, and H5N1 influenza A viruses. One compound (1) was elucidated as a new azaphilone derivative, and four compounds (2-5) were identified as entonaemin A, comazaphilone D, rubiginosin A, and entonaemin B, respectively. Compounds 3 and 4 showed considerable inhibitory activity against three types of neuraminidases with the $IC_{50}$ values of 30.9, 41.8, and $35.7{\mu}M$ for 3 and 46.5, 50.4, and $29.9{\mu}M$ for 4, respectively. This study reveals that the fruiting bodies of G. splendens possess azaphilone derivatives with the NA inhibitory activity. This is the first report on the isolation of neuraminidase inhibitors from the fruiting bodies of G. splendens.

• Korean Journal of Environmental Agriculture
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• v.38 no.3
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• pp.159-165
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• 2019

BACKGROUND: The water footprint (WF) is an indicator of freshwater use that appears not only at direct water use of a consumer or producer, but also at the indirect water use. As an indicator of 'water use', the water footprint includes the green, blue, and grey WF, and differs from the classical measure of 'water withdrawal' because of green and grey WF. This study was conducted to assess and estimate the water footprint of the soybean and Chinese cabbage. METHODS AND RESULTS: APEX model with weather data, soil and water quality data from NAS (National Institute of Agricultural Sciences), and farming data from RDA (Rural Development Administration) was operated for analyzing the WF of the crops. As the result of comparing the yield estimated from APEX with the yield extracted from statistic data of each county, the coefficients of determination were 0.83 for soybean and 0.97 for Chinese cabbage and p-value was statistically significant. The WFs of the soybean and Chinese cabbage at production procedure were 1,985 L/Kg and 58 L/Kg, respectively. This difference may have originated from the cultivation duration. The WF ratios of soybean were 91.1% for green WF and 8.9% for grey WF, but the WF ratios of Chinese cabbage were 41.5% for green WF and 58.5% for grey WF. CONCLUSION: These results mean that the efficiency of water use for soybean is better than that for Chinese cabbage. The results could also be useful as an information to assess environmental impact of water use and agricultural farming on soybean and Chinese cabbage.

• Atmosphere
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• v.29 no.1
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• pp.75-86
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• 2019

In this paper, we introduce a novel Climate & Environment Database System (CEDS). The CEDS is developed by the National Institute of Meteorological Sciences (NIMS) to provide easy and efficient user interfaces and storage management of climate model data, so improves work efficiency. In uploading the data/files, the CEDS provides an option to automatically operate the international standard data conversion (CMORization) and the quality assurance (QA) processes for submission of CMIP6 variable data. This option increases the system performance, removes the user mistakes, and increases the level of reliability as it eliminates user operation for the CMORization and QA processes. The uploaded raw files are saved in a NAS storage and the Cassandra database stores the metadata that will be used for efficient data access and storage management. The Metadata is automatically generated when uploading a file, or by the user inputs. With the Metadata, the CEDS supports effective storage management by categorizing data/files. This effective storage management allows easy and fast data access with a higher level of data reliability when requesting with the simple search words by a novice. Moreover, the CEDS supports parallel and distributed computing for increasing overall system performance and balancing the load. This supports the high level of availability as multiple users can use it at the same time with fast system-response. Additionally, it deduplicates redundant data and reduces storage space.

• Molecules and Cells
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• v.42 no.5
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• pp.397-405
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• 2019

The regulatory role of long noncoding RNA (lncRNA) growth arrest-specific transcript 5 (GAS5) in both cancerous and noncancerous cells have been widely reported. This study aimed to evaluate the role of lncRNA GAS5 in heart failure caused by myocardial infarction. We reported that silence of lncRNA GAS5 attenuated hypoxia-triggered cell death, as cell viability was increased and apoptosis rate was decreased. This phenomenon was coupled with the down-regulated expression of p53, Bax and cleaved caspase-3, as well as the up-regulated expression of CyclinD1, CDK4 and Bcl-2. At the meantime, the expression of four heart failure-related miR-NAs was altered when lncRNA GAS5 was silenced (miR-21 and miR-142-5p were up-regulated; miR-30b and miR-93 were down-regulated). RNA immunoprecipitation assay results showed that lncRNA GAS5 worked as a molecular sponge for miR-142-5p. More interestingly, the protective actions of lncRNA GAS5 silence on hypoxia-stimulated cells were attenuated by miR-142-5p suppression. Besides, TP53INP1 was a target gene for miR-142-5p. Silence of lncRNA GAS5 promoted the activation of PI3K/AKT and MEK/ERK signaling pathways in a miR-142-5p-dependent manner. Collectively, this study demonstrated that silence of lncRNA GAS5 protected H9c2 cells against hypoxia-induced injury possibly via sponging miR-142-5p, functionally releasing TP53INP1 mRNA transcripts that are normally targeted by miR-142-5p.

• Journal of Electrochemical Science and Technology
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• v.12 no.1
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• pp.82-91
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• 2021

This study was conducted to investigate the effect of initial pH, current density, and electrolysis time on process performance in terms of decolorization and chemical oxygen demand (COD) removal from disperse dyebath wastewater (DDW) by mono-polar parallel laboratory scale electrocoagulation (EC) process. COD reduction of 51.3% and decolorization of 92.8% were obtained with operating cost of 0.19 €/㎥ treated wastewater for Al-Al electrode pair, while 90.5% of decolorization and 49.2% of COD reduction were obtained with operating cost of 0.20 €/㎥ treated wastewater for an Fe-Fe electrode pair. The amount of sludge production were highly related to type of the electrode materials. At the optimum conditions, the amount of sludge produced were 0.18 kg/㎥ and 0.28 kg/㎥ for Al-Al and Fe-Fe electrode pairs, respectively. High decolorization can be explained by the hydrophobic nature of the disperse dye, while limited COD removal was observed due to the high dissolved organic matter of the DDW based on auxiliary chemicals. Energy, electrode, and chemical consumptions and sludge handling were considered as major cost items to find a cost-effective and sustainable solution for EC. The contribution of each cost items on operating cost were determined as 10.0%, 51.1%, 30.5% and 8.4% for Al-Al, and they were also determined as 9.0%, 38.0%, 40.5% and 12.5% for Fe-Fe, respectively. COD reduction and decolorization were fitted to first-order kinetic rule.

• The Korean Journal of Food And Nutrition
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• v.35 no.5
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• pp.378-388
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• 2022

This study was conducted to determine the proximate compositions, nutritional components, and antioxidant effects of white and brown enoki mushrooms (Flammulina velutipes). The crude protein and carbohydrate contents were higher in the brown than white mushrooms, whereas the moisture, crude ash, crude lipid, and dietary fiber levels were lower. The mineral contents of the white mushroom was higher than levels obtained in the brown mushroom for the detected components (Ca, Cu, K, Mn, Na, and P). The amount of vitamin B₃ in the brown mushroom was 1.51 mg/100 g, which was 4.5 times higher than that in the white mushroom. The major fatty acids detected were palmitic acid, linoleic acid, and α-linolenic acid. The total polyphenol and flavonoid contents were highest in 70% ethanol extracts of the white and brown mushrooms, respectively. For the 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity, a 70% methanol extract of the white enoki mushrooms showed an activity of 76.4% (p<0.05). For the ferric-reducing antioxidant power (FRAP) activity, a 70% methanol extract of the brown enoki mushrooms showed the highest value. Further, the total flavonoid contents were significantly correlated with the DPPH and FRAP activities.

• Journal of Oral Medicine and Pain
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• v.32 no.1
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• pp.1-8
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• 2007

The purpose of this study was to investigate whether there were any changes in taste sensitivity with recurrent aphthous ulceration. Nintyseven subjects(25 males and 72 females) were included for the study and they were categorized into 2 groups(recurrent aphthous ulceration 27 persons, control 70 persons), recurrent aphthous ulceration group was investigated in the department of Oral Medicine, College of Dentistry, Pusan National University from April, 2005 to August, 2006 and control group was investigated in the clinic at Incheon city from June, 2006 to August, 2006. The electrical taste thresholds were measured using an electrogustometer of the 4 different sites(tongue tip, tongue lateral, circumvallate papilla and soft palate) in oral cavity. The results were as follows ; 1. The electrical taste threshold showed significant lower in the RAU group. 2. The electrical taste threshold showed significant lower in female group, and showed significant lower except soft palate in male group of the RAU group. 3. The electrical taste threshold showed a tendency to increase in all site of the multiple RAU group, but there were no significant differences. 4. The electrical taste threshold showed a tendency to increase in tongue lateral of the acute RAU group, and showed a tendency to increase in tongue tip, circumvallate papilla, soft palate of the chronic RAU group. 5. After treatment, electrical taste threshold was significant increase than initial visit in the RAU group. 6. After treatment, NAS showed a tendency to decrease in the RAU group.