• Title/Summary/Keyword: N-generations

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The development of a mesh generation program using contour line data (등고선 데이터를 이용한 산악지형 유동해석 격자생성 프로그램 개발 및 그 응용)

  • Chin S. M.;Won C. S.;Hur N.
    • Journal of computational fluids engineering
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    • v.9 no.4
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    • pp.7-12
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    • 2004
  • In the present study a semi-automatic mesh generation program has been developed by using DXF file containing contour line data. The program consists of DXF file reader and mapping algorithm. Pre-generated 2-D planar mesh points are to be mapped one by one onto triangular surface whose three vertices are three nearest contour points surrounding the mapping point. The present program has been successfully tested for mesh generations for the road tunnel ventilation analysis and analysis of lava movement in mountain area.

Transfer of Xenomitochondria Containing the Entire Mouse Mitochondrial Genome into a Genetically Modified Yeast Expressing Mitochondrial Transcription Factor A

  • Yoon, Young Geol
    • Journal of Microbiology and Biotechnology
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    • v.30 no.9
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    • pp.1290-1296
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    • 2020
  • Recently, it was reported that entire mammalian mtDNA genomes could be transplanted into the mitochondrial networks of yeast, where they were accurately and stably maintained without rearrangement as intact genomes. Here, it was found that engineered mtDNA genomes could be readily transferred to and steadily maintained in the mitochondria of genetically modified yeast expressing the mouse mitochondrial transcription factor A (Tfam), one of the mitochondrial nucleoid proteins. The transferred mtDNA genomes were stably retained in the Tfam-expressing yeast cells for many generations. These results indicated that the engineered mouse mtDNA genomes introduced in yeast mitochondria could be relocated into the mitochondria of other cells and that the transferred genomes could be maintained within a mitochondrial environment that is highly amenable to mimicry of the biological conditions in mammalian mitochondria.

Femtosecond nonlinear optical shift in photonic bandgapedges of a cholesteric liquid crystal (롤레스테릭 액정의 광결정 가장자리에서의 펨토초 비선형 광학 이동)

  • Jisoo Hwang;N. Y. Ha;H. J. Chang;Park, Byoungchoo;J. W. Wu
    • Proceedings of the Optical Society of Korea Conference
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    • 2003.07a
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    • pp.164-165
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    • 2003
  • A cholesteric liquid crystal (CLC) system exhibits one-dimensional (1-D) Photonic bandgap (PBG) characteristics in the transmission spectrum through a selective Bragg reflection. Related to the nonlinear optical (NLO) processes in a PBG structure of CLC, the inherent periodicity has been exploited to Phase-match the fundamental and the harmonic waves through the umklapp Processes. Near bandgap edges of a CLC, harmonic generations have been shown to be enhanced significantly through the field localization. (omitted)

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Virus-resistant and susceptible transgenic Nicotiana benthamiana plants expressing coat protein gene of Zochini green mottle mosaic virus for LMO safety assessment

  • Park, M.H.;B.E. Min;K.H. Ryu
    • Proceedings of the Korean Society of Plant Pathology Conference
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    • 2003.10a
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    • pp.146.1-146
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    • 2003
  • Transgenic Nicotiana benthmiana plants harboring and expressing coat protein (CP) gene of Zucchini green mottle mosaic virus (ZGMMV) were generated for both virus-resistant screening and complementation analysis of related viruses and environmental safety assessment (SA) of living modified organism (LMO) purposes. Transformation of leaf disc of N. benthamiana was performed using Agrobacterium-mediated method and the pZGCPPGA748 containing the ZGMMV CP and NPTII genes. Two kinds of transgenic homozygous groups, virus-resistant and -susceptible lines, were obtained by screening of challenging homologous virus for T1 generations. Complementation of CP-deficient related virus was analyzed using the susceptible line of ZGMMV. These two pathologically different lines can be useful for host-virus interactions and LMO environmental SA.

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DC Characteristic of Silicon-on-Insulator n-MOSFET with SiGe/Si Heterostructure Channel (SiGe/Si 이종접합구조의 채널을 이용한 SOI n-MOSFET의 DC 특성)

  • Choi, A-Ram;Choi, Sang-Sik;Yang, Hyun-Duk;Kim, Sang-Hoon;Lee, Sang-Heung;Shim, Kyu-Hwan
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2006.06a
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    • pp.99-100
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    • 2006
  • Silicon-on-insulator(SOI) MOSFET with SiGe/Si heterostructure channel is an attractive device due to its potent use for relaxing several limits of CMOS scaling, as well as because of high electron and hole mobility and low power dissipation operation and compatibility with Si CMOS standard processing. SOI technology is known as a possible solution for the problems of premature drain breakdown, hot carrier effects, and threshold voltage roll-off issues in sub-deca nano-scale devices. For the forthcoming generations, the combination of SiGe heterostructures and SOI can be the optimum structure, so that we have developed SOI n-MOSFETs with SiGe/Si heterostructure channel grown by reduced pressure chemical vapor deposition. The SOI n-MOSFETs with a SiGe/Si heterostructure are presented and their DC characteristics are discussed in terms of device structure and fabrication technology.

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Studies on the Effects of the Pine Needle Gall Midge, Thecodiplosis japonensis Uchida et Inouye, on the Growth of the Red Pine, Pinus densiflora Siebold et Zuccarini (I) - Changes in Gall Formation Rate - (솔잎혹파리가 소나무생장(生長)에 미치는 영향(影響)에 관한 연구(硏究)(I) - 충영형성률(虫癭形成率)의 변동(變動) -)

  • Park, Ki Nam;Hyun, Jai Sun
    • Journal of Korean Society of Forest Science
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    • v.61 no.1
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    • pp.20-26
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    • 1983
  • Some aspects of the change in the rate of gall formation on the red pine, Pinus densiflora Siebold et Zuccarini, by the pine needle gall midge, Thecodiplosis japonensis Uchida et Inouye, were investigated at the coastal area in Chung Nam-Do from 1977 to 1982, and were analyzed with the nationwide survey data for 2 years from 1980 to 1981. The results obtained were as follows; the gall formation rate in several areas was compared between two consecutive generations. Four regression equations were established, with X as the gall formation rate in N year and Y as that in (N+1) year: 1) Y=11.2+1.15X (r=0.833) for the stands facing north on the phase of insect population increase, 2) Y=14.3+0.82X (r=0.739) for the stands facing south on the phase of population increase, 3) Y=7.3+0.46X (r=0.478) for stands facing north on the phase of population decrease and 4) Y=11.4+0.19X (r=0.086) for stands facing south on the phase of population decrease. After invasion of the pine needle gall midge into a red pine forest, gall formation rate increased for 6 consecutive generations and then decreased to low level within a period of another 6 years.

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Linkage Disequilibrium Estimation of Chinese Beef Simmental Cattle Using High-density SNP Panels

  • Zhu, M.;Zhu, B.;Wang, Y.H.;Wu, Y.;Xu, L.;Guo, L.P.;Yuan, Z.R.;Zhang, L.P.;Gao, X.;Gao, H.J.;Xu, S.Z.;Li, J.Y.
    • Asian-Australasian Journal of Animal Sciences
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    • v.26 no.6
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    • pp.772-779
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    • 2013
  • Linkage disequilibrium (LD) plays an important role in genomic selection and mapping quantitative trait loci (QTL). In this study, the pattern of LD and effective population size ($N_e$) were investigated in Chinese beef Simmental cattle. A total of 640 bulls were genotyped with IlluminaBovinSNP50BeadChip and IlluminaBovinHDBeadChip. We estimated LD for each autosomal chromosome at the distance between two random SNPs of <0 to 25 kb, 25 to 50 kb, 50 to 100 kb, 100 to 500 kb, 0.5 to 1 Mb, 1 to 5 Mb and 5 to 10 Mb. The mean values of $r^2$ were 0.30, 0.16 and 0.08, when the separation between SNPs ranged from 0 to 25 kb to 50 to 100 kb and then to 0.5 to 1 Mb, respectively. The LD estimates decreased as the distance increased in SNP pairs, and increased with the increase of minor allelic frequency (MAF) and with the decrease of sample sizes. Estimates of effective population size for Chinese beef Simmental cattle decreased in the past generations and $N_e$ was 73 at five generations ago.

Linkage Disequilibrium and Effective Population Size in Hanwoo Korean Cattle

  • Lee, S.H.;Cho, Y.M.;Lim, D.;Kim, H.C.;Choi, B.H.;Park, H.S.;Kim, O.H.;Kim, S.;Kim, T.H.;Yoon, D.;Hong, S.K.
    • Asian-Australasian Journal of Animal Sciences
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    • v.24 no.12
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    • pp.1660-1665
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    • 2011
  • This study presents a linkage disequilibrium (LD) analysis and effective population size ($N_e$) for the entire Hanwoo Korean cattle genome, which is the first LD map and effective population size estimate ever calculated for this breed. A panel of 4,525 markers was used in the final LD analysis. The pairwise $r^2$ statistic of SNPs up to 50 Mb apart across the genome was estimated. A mean value of $r^2$ = 0.23 was observed in pairwise distances of <25 kb and dropped to 0.1 at 40 to 60 kb, which is similar to the average intermarker distance used in this study. The proportion of SNPs in useful LD ($r^2{\geq}0.25$) was 20% for the distance of 10 and 20 kb between SNPs. Analyses of past effective population size estimates based on direct estimates of recombination rates from SNP data demonstrated that a decline in effective population size to $N_e$ = 98.1 occurred up to three generations ago.

Development of a Chronic Skin Wound Defect: A Swine Model (돼지를 이용한 만성피부결손상처의 모델)

  • Sohn, Hyung Bin;Son, Dae Gu;Kim, Jun Hyung;Han, Ki Hwan;Ryoo, Nam Hee;Kwon, Sun Young
    • Archives of Plastic Surgery
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    • v.33 no.5
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    • pp.606-611
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    • 2006
  • Purpose: Animal models of a chronic wound are yet to be fully developed, and animal studies on this subject has yet to take place. The purpose of this study is to create the foundation for research on chronic wound healing based on a swine model, the most similar to that of a human. Methods: Three female 2-3 month old 'yolkshires' were used. Total of eight full thickness skin defects, $6{\times}3cm$ sized, were created on the back of each pigs. Three groups were created for comparison; Group I (n=4) was left as they were after full skin thickness excision, while the excised tissues of Group II (n=3) were turned inside out and sutured so that the epidermis would come in contact with the fascia. Group III (n=3) were excised full skin thickness in depth and silicone blocks were implanted in them. Dressing was not practised so that the wounds would be vulnerable to infection. Results: In Group III, the skin contraction rate was the least among the three groups for each three weeks of observation respectively. Also during the three weeks, bacteral colonization was at the highest among the comparison. On the third week, inflammatory cells were still active, but the generations of epidermis and collagen synthesis were detected minimally. Conclusion: The Group III was relatively the most similar model of chronic wounds. and modification of the silicone blocks, could provide us with a very effective chronic skin wound model similar to human.

A Study on the Electric Guitar -focusing on Fender Stratocaster- (일렉트릭 기타 특징에 관한 연구 -Fender Stratocaster를 중심으로-)

  • Jeong, Sae-Eung;Cho, Tae-seon
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.21 no.5
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    • pp.426-432
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    • 2020
  • Music with the development of the media since the 20th century marks a change into an era where the live performance and music of the masses, which were hard to imagine in previous times, are shared. Based on this cultural trend, teenage music, which has been completely alienated from existing culture, is in line with the birth of Rock 'n' Roll, an event that has entered the mainstream, and the emergence of the guitar, especially the solid body electric guitar. The Fender Stratocaster, which is referred to as the epitome of this electric guitar, has joined the history of popular music for rock 'n' roll. To this day, the immense influence, which still encompasses many followers and generations, has served as a bridge that continues to be reproduced, even in the historical trend of popular music and the status of electric guitars. In addition, even in the rapid development of popular music and media, we will always be able to give true meaning and value to the vitality with the times. This paper examines the features and marks of these Fender Stratocasters.