• Economic and Environmental Geology
• /
• v.28 no.3
• /
• pp.199-211
• /
• 1995

The deep sea camera system could render it possible to obtain the detailed information of the nodule distribution, but difficult to estimate nodule abundance quantitatively. In order to estimate nodule abundance quantitatively from deep seabed photographs, the nodule abundance equation was derived from the box core data obtained in KODOS area(long.: $154^{\circ}{\sim}151^{\circ}W$, lat.: $9^{\circ}{\sim}12^{\circ}N$) during two survey cruises carried out in 1989 and 1990. The regression equation derived by considering extent of burial of nodule to Handa's equation compensates for the abundance error attributable to partial burial of some nodules by sediments. An average long axis and average extent of burial of nodules in photographed area are determined according to the surface textures of nodules, and nodule coverage is calculated by the image analysis method. Average nodule abundance estimated from seabed photographs by using the equation is approximately 92% of the actual average abundance in KODOS area. The measured sampling points by box core or free fall grab are in general very sparse and hence nodule abundance distribution should be interpolated and extrapolated from measured data to uncharacterized areas. The another goal of this study is to depict continuous distribution of nodule abundance in KODOS area by using PC-version of geostatistical model in which several stages are systematically proceeded. Geostatistics was used to analyse spatial structure and distribution of regionalized variable(nodule abundance) within sets of real data. In order to investigate the spatial structure of nodule abundance in KODOS area, experimental variograms were calculated and fitted to a spherical models in isotropy and anisotropy, respectively. The spherical structure models were used to map out distribution of the nodule abundance for isotropic and anisotropic models by using the kriging method. The result from anisotropic model is much more reliable than one of isotropic model. Distribution map of nodule abundance produced by PC-version of geostatistical model indicates that approximately 40% of KODOS area is considered to be promising area(nodule abundance > $5kg/m^2$) for mining in case of anisotropy.

• Health Policy and Management
• /
• v.9 no.1
• /
• pp.30-71
• /
• 1999

There has been a dramatic increase in public awareness regarding dementia during recent years. However, dementia remains a family affair and patients do not receive adequate care in Korea. This study aims to assist patients and their caregivers by establishing Home and Community based Long-Term Care in a city. The data collected for analysis include five main categories: dementia prevalence, limitations of daily activities of patients, burden of caregivers, the services that patient's family want to utilize, the resources that handle dementia in the community. Major findings can be summarized as follows: 1)The prevalence rate of dementia for elderly people is 13.1 per 100 persons. Alzheimer's disease amount to 38.9% of dementia patients and vascular dementia account for 36.7% of them 2)Eight out of ten patients have mild dementia. Almost all patients have normal ADL. IADL, however, shows different picture. In every items of IADL, about 60% of patients reveals some limitations. 3)The proportion of patients who had medical diagnosis is as low as 20%. Families of patients think dementia as normal aging process and medical doctors in the community do not give special concern to dementia patients. 4)Caregivers does not have proper social support. They suffer from long care time, experience large obstacles in respect of health, daily living, and social activity. 5)Health center and Community welfare center have launched some programs-consultation, home-visiting nursing, day care center, voluntary force mobilization and so on-for dementia patients. But they do not perform expected roles and functions because of lack of skilled personnels and inadequate coordination of relevant organizations for dementia care. 6)Families of dementia patients prefer home helper and home-visiting nurse to hospitalization. For the future, however, demand for institution-based long-term services will increase. We develope community dementia care model based on above findings as follows: 1)Health center execute community cardiovascular control program for the prevention of vascular dementia. 2)Refer to epidemiologic characteristics of patients and preference of family, the most urgent task for dementia care in this city is to expand and organize Home and Community based Long-Term Care. 3)For the continuous and comprehensive care, care plan for a patient must be prepared. Case management team should be builded to prepare this plan and coordinate relevant resources. 4)Special long-term care unit for dementia will be needed in a near future. This unit should have multiple functions, such as day-care center, short stay facility, training center for relevant personnels, besides long-term nursing home considering effective care of dementia and efficient operation of the facility. 5)Voluntary workers deserve their due efforts. Incentive mechanisms must be developed to activate voluntary activities.

• Journal of Yeungnam Medical Science
• /
• v.14 no.2
• /
• pp.350-358
• /
• 1997

We studied the effects of adding a single bolus(500 mg) of sodium thiopental to a continuous infusion of low-dose fentanyl on plasma beta-endorphin immunoreactivity(iBE) responses to cardiopulmonary bypass(CPB) in 28 patients undergoing elective coronary artery bypass grafting or valve procedures. Thiopental was injected just prior to the initiation of CPB. The iBE levels and the hemodynamic indices such, as mean arterial pressure, cardiac output and systemic vascular resistance were measured before CPB, at 30 min and again at 60 min after the initiation of the bypass. The results were as follows. After the initiation of CPB, iBE levels increased at 30 min and 60 min(P=0.006, P=0.004 respectively) in the control group, but not in the thiopental group. There were significant differences in the changes of iBE levels between the groups(F=8.7, G-G=0.002, P=0.001). The hemodynamic indices were similar in both groups. In conclusion, pretreatment with thiopental just before the initiation of CPB prevents the stress-induced beta-endorphin response to CPB.

• Journal of the Korean association of regional geographers
• /
• v.11 no.1
• /
• pp.29-39
• /
• 2005

Silk Road is the term involving all traffic roads connecting the East to the West, and ancient Korean culture has became globalized through Silk Road. In this paper, natural environment of Silk Road is considered as fundamental data in order to understand the Western culture introduced through Silk Road. Silk Road region is classified into Loess Plateau district; arid basin district; and high mountains district; Hesi Corridor(河西回廊) is the transition zone that the southeastern part of $W{\breve{u}}w{\bar{e}}i$(武威) is Loess Plateau district; other northwestern part is arid basin district Loess Plateau district, composed of homogeneous fines, has experienced dramatic soil loss by bringing under cultivation. At recent times, reforestation and construction of check-dam have been in operation to cope with this problems, Arid basin district; although at midlatitude, is desert climate because it is far from the ocean and is surrounded by high mountains. Oasis of Hesi Corridor is continuous linearly, but that of arid basin district is sporadic. In $H{\bar{a}}mi$ and $T{\breve{u}}l{\breve{u}}f{\bar{a}}n$(吐魯番) fruit-growing using karez flourishes, And glacier of $Ti{\bar{a}}nshian$(天山) Mts. and $Q{\bar{i}}lian$(祁連) Mts. is very important to arid basin district because of supplying water resource. In the tundra zone surrounding alpine glacier, are distributed widely solifluction lobes and earth hummocks.

• Journal of KIISE:Computer Systems and Theory
• /
• v.26 no.8
• /
• pp.984-998
• /
• 1999

최근 개인 휴대 통신에 대한 관심도가 증가하면서 B-ISDN (Broadband Integrated Services Digital Network)과 같은 기존의 유선 망에서 제공하던 다양한 멀티미디어 응용 지원을 무선 망으로 확장시키기 위한 연구가 활발히 진행되고 있다. 그러나 기존의 유선 망에서는 멀티미디어 응용 지원을 위해 QoS (Quality of Service) Provisioning에 관한 많은 연구가 되어 있으나 무선 망에서는 이동성과 무선 전파의 열악한 전송으로 인해 새로운 QoS Provisioning 방법에 관한 연구가 필수적이다. 본 논문에서는 이러한 무선 망의 특수성으로 인해 발생할 수 있는 서비스의 질 저하와 강제 종료를 줄임으로써 지속적인 QoS를 보장해 주고 한정된 무선 자원을 효율적으로 사용하며 처리에 의한 오버헤드를 줄이기 위하여 다음과 같은 세 가지 방법을 제안하였다. 첫째, 핸드오프 강제 종료율을 줄이기 위하여 대역폭 예약 방법을 사용하되 특정 셀의 트래픽 특성에 맞게 또한 시간대에 따른 트래픽 특성에 따라 예약 대역폭의 양을 조절하는 적응적 대역폭 예약 방법이다. 둘째, 많은 경우 각 셀의 트랙픽 변화는 일정한 주기로 변화한다는 특성에 따라 과거의 트래픽 정보를 이용하는 예측 기반의 대역폭 예약 방법이다. 마지막으로 호의 종류, 트래픽 특성, 단말기의 이동 속도에 따라 다른 우선 순위에 의해 호 수락 제어를 수행하는 우선 순위 기반의 호 수락 제어를 제안하였다. 시뮬레이션을 통하여 기존에 제안된 방법과 성능 비교하여, 요구되는 수준의 QoS 보장과 효율적인 자원의 사용, 요구되는 처리비용의 최소화를 통해 전체 시스템의 성능 향상을 입증하였다.Abstract As interest in wireless hand-held terminals and in personal communications services increases recently, there have been broad studies on the ways to support multimedia applications provided in wired networks such as B-ISDN (Broadband Integrated Services Digital Network) in wireless networks. However, since many studies have focused on Quality of Service (QoS) Provisioning in wired networks to provide multimedia applications, new methods of QoS Provisioning are needed in wireless networks to resolve the problem of wireless channel fading and the difficulty of mobility occurred in wireless networks. This paper proposes three schemes of QoS Provisioning in wireless networks which will make continuous QoS guarantee and efficient use of limited wireless resources possible. The first scheme reserves bandwidth in proportion to the amount of real-time traffic in the neighbor cells to decrease the handoff dropping rate of delay sensitive real-time connections, adapting reserved bandwidth for efficient resource utilization. The second scheme is predictive bandwidth reservation scheme that utilizes the past handoff information. It can decrease overheads required to adapt bandwidth reservation. The last scheme is priority-based call admission control prioritizing traffic type (real-time traffic/ non-real-time traffic), connection type (new connection /handoff connection), and mobile terminal speed (fast mobile/slow mobile). Simulation results show that the proposed QoS Provisioning schemes improve the total system performance by achieving three goals - required QoS guarantee, higher bandwidth utilization and less overhead.

• Strategy21
• /
• s.42
• /
• pp.5-52
• /
• 2017

Debates about introducing nuclear submarines have been a main issue in Korea. The highest officials and the government has started to think seriously about the issue. Yet there were no certain decision to this issue or any agreements with US but it is still necessary to review about introducing nuclear submarines, the technologies and about the business. The reason for such issues are the highest officials of Korea to build nuclear submarine, nK's nuclear development and SLBM launching. ROKN's nuclear submarine's necessity will be to attack(capacity to revenge), defend(anti-SSBN Operation) and to respond against neighboring nation's threat(Russia, Japan, China). Among these nations, US, Russia (Soviet Union), Britain, France had built their submarines in a short term of time due to their industrial foundation regarding with nuclear propulsion submarines. However China and India have started their business without their industrial foundation prepared and took a long time to build their submarines. Current technology level of Korea have reached almost up to US, Russia, Britain and France when they first built their nuclear propulsion submarines since we have almost completed the business for the Changbogo-I,II and almost up to complete building the Changbogo-III which Korea have self designed/developed. Furthermore Korea have reached the level where we can self design large nuclear reactors and the integrated SMART reactor which we can call ourselves a nation with worldwide technologies. If introducing the nuclear submarine to the Korea gets decided, first of all we would have to review the technological problems and also introduce the foreign technologies when needed. The methods for the introduction will be developments after loans from the foreign, productions with technological cooperations, and individual production. The most significant thing will be that changes are continuous and new instances are keep showing up so that it is important to only have a simple reference to a current instances and have a review on every methods with many possibilities. Also developing all of the technologies for the nuclear propulsion submarines may be not possible and give financial damages so there may be a need to partially introduce foreign technologies. For the introduction of nuclear propulsion submarines, there must be a resolution of the international regulations together with the international/domestics resistances and the technological problems to work out for. Also there may be problem for the requirement fees to solve for and other tough problems to solve for. However nuclear submarines are powerful weapon system to risk everything above. This is an international/domestically a serious agenda. Therefore rather than having debates based on false facts, there must be a need to have an investigations and debates regarding the nation's benefits and national security.

• Journal of Korean Library and Information Science Society
• /
• v.9
• /
• pp.179-211
• /
• 1982

Many problems which today's research libraries are confronted with should be taken the measures to find some solutions in any ways. The purpose of this study is to identify the main stream of chaining of research libraries as an existing collector and distributor of scholarly information into a communication system adopting the concept of resource sharing and on-line bibliographic search as some possible ways for solutions. The conclusions of this study can be summarized as follows: 1) The research libraries will be imposed on more and more responsibilities to be a reservoir of the intellectual heritage of an individual, a nation and mankind. 2) The research libraries in the near future will have to develop their collections in the new environment of austerity with the limited budget. 3) It is more desirable for the future research libraries to have the attitude that they are in the business of information and communication rather than being an entity as "a library". 4) The resource sharing developed to solve the severe problems confrontal by research libraries will improve the organizational and technical mechanism for the access to the scholarly information. 5) The research libraries will produce more and more bibliographic database to expand the library materials which can be available and shared. 6) Though on-line search service will be sure to provide a considerable profit to the scholarly information users, it will take a long time for this service to be popularize because of the high ratio of service fee. 7) Two problems should be solved for the efficient service by on-line search. One is the continuous, updating training for the professional librarians. The other is that the common efforts for the quality control and standardization of data base by the data base producers should be made. 8) Taking all the items of the conclusions derived from the study of research libraries mainly in the United States into a consideration, the followings should be paid an attention. - The status-quo of the research libraries in Korea should be analyzed in very detailed and accurate way. - The problems of research libraries in Korea as the major scholarly communication system should be clarified based on the analysis. - The measures for the problems should be taken in the light of the unique characteristics of korean environment. - For the developing the most efficient measures, the formal organize action to lead and govern the long-aimed study on the problems of research libraries should be established and the government-level su n.0, pport for the legislation and finance should be provided for the realization of the result of the study.

• Korean Journal of Clinical Pharmacy
• /
• v.14 no.1
• /
• pp.11-23
• /
• 2004

Although most children with idiopathic nephrotic syndrome respond to corticosteroid therapy, many responders show steroid dependency and frequent relapse. In these children, one of the major problems is the serious side effects resulting from continuous steroid therapy. Thus, this study was conducted to assess the therapeutic efficacy and safety of six-month cyclosporine treatment with the low-dose deflazacort therapy in children with nephrotic syndrome. Thirty children with steroid dependence (SD), frequent relapse (FR) and steroid resistance (SR) were enrolled in this study. They were treated with 6-month oral cyclosporine $(Cypol-N^{(R)})$ plus the low-dose deflazacort $(Calcort^{(R)})$ therapy at Samsung Medical Center from September 2002. The dosage of cyclosporine was started at 5 mg/kg/day and was monthly adjusted to maintain clinical remission and/or a trough blood level, while deflazacort dosage was reduced gradually. Clinical evaluation and monitoring of cyclosporine toxicity were performed every $2\sim4$ weeks. Outcomes were compared to the latest sir-month period of steroid only therapy before cyclosporine treatment. Student's t-test and ANOVA were used for statistical analysis. Out of 28 children with SD and FR, 23 $(82.1\%)$ sustained remission, and 5 $(17.9\%)$ experienced 1 or 2 relapses during therapy. Out of 2 children with SR, 1 child sustained remission, and 1 child showed no response. The mean duration of remission and occurrence of relapse were significantly improved (p <.0001). In addition, the mean dosage of steroid was significantly reduced (p=.003). Although a number of adverse effects occurred in this study, they were not so serious as to necessitate discontinuation of the therapy. No nephrotoxicity was observed. Twenty out of the 28 children who had been in remission relapsed after withdrawal of cyclosporine. Fifteen of these children showed relapse within a month. These results demonstrated that the combination of cyclosporine with the low-dose deflazacort was efficient and safe in children with SD and FR during the six-month treatment. However, further studies are necessary in order to resolve the problem of high relapse rate after discontinuation of cyclosporine.

• Asian Pacific Journal of Cancer Prevention
• /
• v.16 no.17
• /
• pp.7975-7979
• /
• 2015

Purpose: This study aimed to explore the value of IHC4 in predicting pathological response after neoadjuvant chemotherapy in patients with hormonal receptor (HR)-positive breast cancer (BC). Materials and Methods: In this retrospective exploratory study, data for 68 HR-positive BC patients who received neoadjuvant chemotherapy were recorded. IHC4 scores were calculated based on estrogen receptors/progesterone receptors, Ki-67 and HER2 status. Logistic and ordinal regression analyses in addition to likelihood ratio test were used to explore associations of IHC4 scores and other clinico-pathological parameters with pathological complete response (pCR) and pathological stage. Results: Taking the 25th percentile as the cut-off, a lower IHC4 score was associated with an increased probability of pCR (low; 52.9% vs. High; 21.6%, OR=4.1, 95% CI=1.28-13.16, p=0.018) and a lower pathological stage (OR=3.9, 95% CI=1.34-11.33, p=0.012). When the IHC4 score was treated as a continuous variable, a lower score was again associated with an increased probability of pCR (OR=1.010, 95% CI=1.001-1.018, p=0.025) and lower pathological stage (OR=1.009, 95% CI=1.002-1.017, P=0.008). Lower clinical stage was associated with a better pCR rate that was of borderline significance (P=0.056). When clinical stage and IHC4 score were incorporated together in a logistic model, the likelihood ratio test gave a P-value of 0.004 after removal of the IHC4 score and 0.011 after removal of the stage, indicating a more significant predictive value of the IHC4 score for pCR. Conclusions: This study suggests that the IHC4 score can predict pathological response to neoadjuvant chemotherapy in HR-positive BC patients. This finding now needs to be validated in a larger cohort of patients.

• Asian Pacific Journal of Cancer Prevention
• /
• v.14 no.11
• /
• pp.6311-6314
• /
• 2013

Background: While 5-port laparoendoscopic radical prostatectomy is standard practice, efforts have been focused in developing a single port surgery for cosmetic reasons. However, this is still in the pioneering stage considering the challenging nature of the surgical procedures. We have therefore focused on reduced port surgery, using only 2-ports. In this study, we compared 2-port laparoendoscopic radical prostatectomy (2-port RP) and conventional 5-port laparoscopic radical prostatectomy (LRP) for clinically localized prostate carcinoma and evaluated the potential advantages of each. Materials and Methods: From January 2010 to December 2010, all 23 patients with clinically localized prostate cancer underwent LRP. Starting November, 2010, when we introduced the reduced port approach, we performed this procedure for 22 consecutive patients diagnosed with early-stage prostate cancer (cT1c, cT2N0). The patients were matched 1:1 to 2-port RP or LRP for age, preoperative serum PSA level, clinical stage, biopsy and pathological Gleason grade, surgical margin status, pad-free rates and post-operative pain. Results: There was a significant difference in operative time between the 2-port RP and LRP groups ($286.5{\pm}63.3$ and $351.8{\pm}72.4$ min: p=0.0019, without any variation in blood loss (including urine) ($945.1{\pm}479.6$ vs $1271.1{\pm}871.8ml$: p=0.13). The Foley catheter indwelling period was shorter in the 2 port RP group, but without significance ($5.6{\pm}1.8$ vs $8.0{\pm}5.6$ days: p=0.057) and the total perioperative complication rates for 2 port RP and LRP were comparable at 4.5% and 8.7% (p=0.58). There was an improvement in pad-free rates up to 6 months follow-up (p=0.090), and significantly improvement at 1 year (p=0.040). PSA recurrence was 1 (4.5%) in 2-port RP and 2 (8.7%) in LRP. Continuous epidural anesthesia was used in most of LRP patients (95.7%) and in early 2-port RP patients (40.9%). In these patients, average total amount of Diclofenac sodium was 27.8mg/patient in 2-port RP and 50.0mg/patient in LRP. Conclusions: Thus the reduced port approach is as efficacious as LRP in terms of many outcome measures, with significant cosmetic advantages and reduction in post surgical pain. This method can be readily performed safely and therefore can be recommended as a standard laparoscopic surgery for prostate cancer in the future.