• Nuclear Engineering and Technology
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• v.29 no.1
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• pp.35-44
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• 1997

Critical too-Phase flow rates of subcooled water through Short Pipes (L 140039n) with small diameters (D$\leq$7.15 min) have been experimentally investigated for wide ranges of subcooling (0~199$^{\circ}C$) and pressure (0.5~2.0 MPa). To examine the effects of various parameters (i.e., the location of flashing inception, the degree of subcooling, the stagnation temperature and pressure, and the pipe size) on the critical two-phase flow rates of subcooled water through short pipes with small diameters, a total of 135 runs were made for various combinations of test parameters using four different L/D test sections. Experimental results that show effect of various parameters on subcooled critical two phase flow rates are presented in the form of graphs such as the dimensionless mass flux ( $G^{*}$) versus the dimensionless subcooling ( $T_{sub}$$^{*}$) curve. An empirical correlation expressed in terms of a dimensionless subcooling is also obtained for subcooled two-phase flow rates through present test sections. Comparisons between the mass fluxes calculated by present correlation and a total of 755 selected experimental data points of 9 different investigators show that the agreement is fairly good except for very low subcooling data obtained from small L/D (less than 10) orifices.s.s.s.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2005.10a
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• pp.539-542
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• 2005

In this study, we investigated the influence of vibrational stimulation on postural control. To study the effect, the sway of the center of pressure was observed fur two different visual conditions and for three different patterns of vibrational stimulation on plantar area. The two visual conditions were normal condition with visual feedback and blind condition with both eyes closed. The three vibrational stimulations were white noise, constant vibration, and vibration with amplitude modulations (sine curve modulation). The experimental results showed that the sway of the center of pressure distinctively reduced with white noise vibrational stimulation. This result showed that it's possible to use vibrational stimulation for improving the ability of postural control.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.13 no.11
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• pp.5578-5586
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• 2012

The accurate estimation of discharge is very essential as the important factor of river design for the utilization and flood control, hydraulic construction design. The present discharge production is using the stage-discharge relationship curve in the river. The rating curve uses the method by predicting the discharge based on regression analysis using the measured stage and discharge data in a flood season. The method is comparatively convenient and has especially advantages in that it can predict the discharge having the difficulty of observation in a flood season. However, this method has basically room for improvement because the method only uses the relationship between stage and discharge, and doesn't reflect the hydraulic parameters such as hydraulic radius, energy slope, roughness, topography, etc.. Therefore, in this study, discharge was predicted using the convenient calculation method with empirical parameters of the Manning and Chezy equations, which were proposed by Choo et at (2011) in KSCE as a new methodology for estimating discharge in open channel. The proposed method can conveniently estimate empirical parameters in both of Manning and Chezy equations and the discharge is estimated in the open channels. There are proved by using data measured in meandering lab. channel and India canal and the accuracies show about determination coefficient 0.8. Accordingly, this method will be used in actual field if this study is continuously conducted.

• Korean Journal of Materials Research
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• v.23 no.12
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• pp.714-721
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• 2013

A stoichiometric mixture of evaporating materials for $ZnAl_2Se_4$ single-crystal thin films was prepared in a horizontal electric furnace. These $ZnAl_2Se_4$ polycrystals had a defect chalcopyrite structure, and its lattice constants were $a_0=5.5563{\AA}$ and $c_0=10.8897{\AA}$.To obtain a single-crystal thin film, mixed $ZnAl_2Se_4$ crystal was deposited on the thoroughly etched semi-insulating GaAs(100) substrate by a hot wall epitaxy (HWE) system. The source and the substrate temperatures were $620^{\circ}C$ and $400^{\circ}C$, respectively. The crystalline structure of the single-crystal thin film was investigated by using a double crystal X-ray rocking curve and X-ray diffraction ${\omega}-2{\theta}$ scans. The carrier density and mobility of the $ZnAl_2Se_4$ single-crystal thin film were $8.23{\times}10^{16}cm^{-3}$ and $287m^2/vs$ at 293 K, respectively. To identify the band gap energy, the optical absorption spectra of the $ZnAl_2Se_4$ single-crystal thin film was investigated in the temperature region of 10-293 K. The temperature dependence of the direct optical energy gap is well presented by Varshni's relation: $E_g(T)=E_g(0)-({\alpha}T^2/T+{\beta})$. The constants of Varshni's equation had the values of $E_g(0)=3.5269eV$, ${\alpha}=2.03{\times}10^{-3}eV/K$ and ${\beta}=501.9K$ for the $ZnAl_2Se_4$ single-crystal thin film. The crystal field and the spin-orbit splitting energies for the valence band of the $ZnAl_2Se_4$ were estimated to be 109.5 meV and 124.6 meV, respectively, by means of the photocurrent spectra and the Hopfield quasicubic model. These results indicate that splitting of the ${\Delta}so$ definitely exists in the ${\Gamma}_5$ states of the valence band of the $ZnAl_2Se_4/GaAs$ epilayer. The three photocurrent peaks observed at 10 K are ascribed to the $A_1$-, $B_1$-exciton for n = 1 and $C_{21}$-exciton peaks for n = 21.

• Nutrition Research and Practice
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• v.2 no.4
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• pp.200-203
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• 2008

Obesity has become a worldwide health problem. Orlistat, an inhibitor of pancreatic lipase, is currently approved as an anti-obesity drug. However, gastrointestinal side effects caused by Orlistat may limit its use. In this study the inhibitory activities of dandelion (Taraxacum officinale) against pancreatic lipase in vitro and in vivo were measured to determine its possible use as a natural anti-obesity agent. The inhibitory activities of the 95% ethanol extract of T. officinale and Orlistat were measured using 4-methylumbelliferyl oleate (4-MU oleate) as a substrate at concentrations of 250, 125, 100, 25, 12.5 and $4\;{\mu}g/ml$. To determine pancreatic lipase inhibitory activity in vivo, mice (n=16) were orally administered with com oil emulsion (5 ml/kg) alone or with the 95% ethanol extract of T. officinale (400 mg/kg) following an overnight fast. Plasma triglyceride levels were measured at 0, 90, 180, and 240 min after treatment and incremental areas under the response curves (AUC) were calculated. The 95% ethanol extract of T. officinale and Orlistat, inhibited, porcine pancreatic lipase activity by 86.3% and 95.7% at a concentration of $250\;{\mu}g/ml$, respectively. T. officinale extract showed dose-dependent inhibition with the $IC_{50}$ of $78.2\;{\mu}g/ml$. A single oral dose of the extract significantly inhibited increases in plasma triglyceride levels at 90 and 180 min and reduced AVC of plasma triglyceride response curve (p<0.05). The results indicate that T. officinale exhibits inhibitory activities against pancreatic lipase in vitro and in vivo. Further studies to elucidate anti-obesity effects of chronic consumption of T. officinale and to identify the active components responsible for inhibitory activity against pancreatic lipase are necessary.

• Asian Pacific Journal of Cancer Prevention
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• v.17 no.3
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• pp.1115-1118
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• 2016

Background: There is controversy about ablation efficacy of low or high doses of radioiodine-131 (RAI) in patients with differentiated thyroid cancers (DTC). The purpose of this prospective study was to determine efficacy of 30 mCi and 100 mCi of RAI to achieve successful ablation in patients with low to intermediate risk DTC. Materials and Methods: This prospective cross sectional study was conducted from April 2013 to November 2015. Inclusion criteria were patients of either gender, 18 years or older, having low to intermediate risk papillary and follicular thyroid cancers with T1-3, N0/N1/Nx but no evidence of distant metastasis. Thirty-nine patients were administered 30 mCi of RAI while 61 patients were given 100 mCi. Informed consent was acquired from all patients and counseling was done by nuclear physicians regarding benefits and possible side effects of RAI. After an average of 6 months (range 6-16 months; 2-3 weeks after thyroxin withdrawal), these patients were followed up for stimulated TSH, thyroglobulin (sTg) and thyroglobulin antibodies, ultrasound neck (U/S) and a diagnostic whole body iodine scan (WBIS) for ablation outcome. Successful ablation was concluded with stimulated Tg< 2ng/ml with negative antibodies, negative U/S and a negative diagnostic WBIS (triple negative criteria). ROC curve analysis was used to find diagnostic strength of baseline sTg to predict successful ablation. Results: Successful ablation based upon triple negative criteria was 56% in the low dose and 57% in the high dose group (non-significant difference). Based on a single criterion (follow-up sTg<2 ng/ml), values were 82% and 77% (again non-significant). The ROC curve revealed that a baseline sTg level ${\leq}7.4ng/ml$ had the highest diagnostic strength to predict successful ablation in all patients. Conclusions: We conclude that 30 mCi of RAI has similar ablation success to 100 mCi dose in patients with low to intermediate risk DTC. A baseline $sTg{\leq}7.4ng/ml$ is a strong predictor of successful ablation in all patients. Low dose RAI is safer, more cost effective and more convenient for patients and healthcare providers.

• Investigative Magnetic Resonance Imaging
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• v.25 no.3
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• pp.164-171
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• 2021

Purpose: Mild cognitive impairment (MCI) is a prodromal stage of Alzheimer's disease (AD). Brain atrophy in this disease spectrum begins in the medial temporal lobe structure, which can be recognized by magnetic resonance imaging. To overcome the unsatisfactory inter-observer reliability of visual evaluation, quantitative brain volumetry has been developed and widely investigated for the diagnosis of MCI and AD. The aim of this study was to assess the prediction accuracy of quantitative brain volumetry using a fully automated segmentation software package, NeuroQuant^®, for the diagnosis of MCI. Materials and Methods: A total of 418 subjects from the Korean Brain Aging Study for Early Diagnosis and Prediction of Alzheimer's Disease cohort were included in our study. Each participant was allocated to either a cognitively normal old group (n = 285) or an MCI group (n = 133). Brain volumetric data were obtained from T1-weighted images using the NeuroQuant software package. Logistic regression and receiver operating characteristic (ROC) curve analyses were performed to investigate relevant brain regions and their prediction accuracies. Results: Multivariate logistic regression analysis revealed that normative percentiles of the hippocampus (P < 0.001), amygdala (P = 0.003), frontal lobe (P = 0.049), medial parietal lobe (P = 0.023), and third ventricle (P = 0.012) were independent predictive factors for MCI. In ROC analysis, normative percentiles of the hippocampus and amygdala showed fair accuracies in the diagnosis of MCI (area under the curve: 0.739 and 0.727, respectively). Conclusion: Normative percentiles of the hippocampus and amygdala provided by the fully automated segmentation software could be used for screening MCI with a reasonable post-processing time. This information might help us interpret structural MRI in patients with cognitive impairment.

• Journal of The Korean Society of Agricultural Engineers
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• v.55 no.1
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• pp.17-29
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• 2013

Long-Term Hydrologic Impact Assessment (L-THIA) model which is a distributed watershed model was applied to analyze the spatial distribution of surface runoff and nonpoint source pollutant loading from Imha watershed during 2001~2010. L-THIA CN Calibration Tool linked with SCE-UA was developed to calibrate surface runoff automatically. Calibration (2001~2005) and validation (2006~2010) of monthly surface runoff were represented as 'very good' model performance showing 0.91 for calibration and 0.89 for validation as Nash-Sutcliffe (NS) values. Average annual surface runoff from Imha watershed was 218.4 mm and Banbyun subwatershed was much more than other watersheds due to poor hydrologic condition. Average annual nonpoint source pollutant loading from Imha wateshed were 2,295 ton/year for $BOD_5$, 14,752 ton/year for SS, 358 ton/year for T-N, and 79 ton/year for T-P. Amount of pollutant loading and pollutant loading rates from Banbyun watershed were much higher than other watersheds. As results of analysis of loading rate from grid size ($30m{\times}30m$), most of high 10 % of loading rate were generated from upland. Therefore, major hot spot area to manage nonpoint source pollution in Imha watershed is the combination of upland and Banbyun subwatershed. L-THIA model is easy to use and prepare input file and useful tool to manage nonpoint source pollution at screening level.

• Transactions of Materials Processing
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• v.29 no.5
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• pp.257-264
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• 2020

This paper is concerned with the influence of the plastic property of the rivet on the numerical prediction of the Self-Piercing Rivet (SPR) Joining. In order to predict the plastic property of the rivet, a ring compression specimen was directly fabricated from the rivet used for the mechanical joining of dissimilar materials, and the FE analysis together with the ring compression test was iteratively carried out by changing the plastic property of the rivet. For reliable FE analysis, a friction coefficient was estimated based on a friction calibration curve, measuring the reductions in inner diameter and height of the ring specimen after the compression test. From each simulation result, the force-displacement curves were then compared from each other so as to obtain the rivet plastic property that shows good agreement with the experimental result. The SPR joining between GA590 1.0t and Al5052 2.0t was conducted, and the numerical prediction was performed with the use of the plastic property evaluated based on the inverse analysis and the one referred from Mori et al. [11]. Comparison of the experiment and the numerical predictions in terms of the interlock and bottom thickness revealed that the reliable evaluation of the plastic property of the rivet is necessary for the trustworthy numerical prediction of the SPR joining.

• Journal of Korean Society on Water Environment
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• v.31 no.6
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• pp.653-664
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• 2015

TPLMS (Total water pollutant load management system) that is the most powerful water-quality protection program have been implemented since 2004. In the implementation of TPLMS, target water-quality and permissible discharged load from each unit watershed can be decided by water-quality modeling. And NPS (Non-point sources) discharge coefficients associated with certain (standard) flow are used on estimation of input data for model. National Institute of Environmental Research (NIER) recommend NPS discharge coefficients as 0.15 (Q₂₇₅) and 0.50 (Q₁₈₅) in common for whole watershed in Korea. But, uniform coefficient is difficult to reflect various NPS characteristics of individual watershed. Monthly NPS discharge coefficients were predicted and estimated using surface flow and water-quality from HSPF watershed model in this study. Those coefficients were plotted in flow duration curve of study area (Palger stream and Geumho C watershed) with monthly average flow. Linear regression analysis was performed about NPS discharge coefficients of BOD, T-N and T-P associated with flow, and R² of regression were distributed in 0.893~0.930 (Palger stream) and 0.939~0.959 (Geumho C). NPS Discharge coefficient through regression can be estimated flexibly according to flow, and be considered characteristics of watershed with watershed model.