• 제목/요약/키워드: N-Debenzylations

검색결과 1건 처리시간 0.014초

Oxidative N-Debenzylation of N-Benzyl-N-substituted Benzylamines Catalyzed by Cytochrome P450

  • Kim, Sung-Soo;Lin, Gang;Yang, Ji-Won
    • Bulletin of the Korean Chemical Society
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    • 제25권2호
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    • pp.249-252
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    • 2004
  • Cytochrome P450 (P450)/$O_2$/NADPH engender electron transfer reaction of N-benzyl-N-substituted benzylamines to yield corresponding radical cation 1 that is simultaneously converted into 2 and 3. Subsequently, expulsion of proton and hydroxylation yielding a-hydroxylamines are followed by formation of benzaldehydes and benzylamines.