• Journal of Korean Medicine Rehabilitation
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• v.19 no.2
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• pp.289-302
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• 2009

Objectives : This study was performed in order to investigate the relation of body composition analysis and radiological parameter(lumbosacral angle, lumbar lordortic angle, lumbar gravity line). Methods : This study was carried out with the data from comprehensive medical testing. 75 subject aged 20-59 performed the segmental bioelectrical impedance analysis, questionnaire. And lumbosacral angle, lumbar lordortic angle and lumbar gravity line were measured in the standing position x-ray. Then we analyzed the data. Results : Low back pain(LBP) prevalence in high obesity index(Body Mass Index(BMI), Percentage of Body Fat(PBF), Waist Hip Ratio(WHR)) group was higher than LBP prevalence in normal obesity index group(p<0.01). In LBP group, lumbosacral angle, lumbar lordortic angle were significantly lager than Non-LBP group(p<0.001). And 75% of LBP group indicated abnormal lumbar gravity line ratio(0.67 < Normal lumbar gravity line ratio <1.00). When it comes to analyze relation between obesity index and radiological parameter, no-significant change was seen. Conclusions : This study carried as following research after the study on relation of obesity, LBP and trunk muscle strength. Results from this investigation showed positive correlation between obesity and LBP prevalence. But obesity index didn't indicate significant correlation with structural changes of lumbar vertebrae. When considering prior research, trunk muscle strength changes were more related to LBP prevelence in obese people. This results are expected to explain causes of LBP in obese group.

• International Journal of Safety
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• v.11 no.1
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• pp.22-25
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• 2012

Scoliosis can be biomechanically described as a three dimensional deformity of the spine, with deviations from the physiologic curves in the sagittal and frontal planes, usually combined with intervertebral rotation. Various factors are suspected such as genetic defects, uneven growth of the vertebrae, hormonal effects, abnormal muscular activity, postural problems, or a mix of some of these elements, but its initial cause is known in only 15-20% cases. The screening test for diagnosing scoliosis is called the Adams Forward Bend Test. During the experiment, the subjects were asked to bend over, with arms dangling, until a curve could be observed. The Scoliometer was placed on the back of the subjects and used to measure the difference between the left and right apex of the curve in the thoracic, thoracolumbar and lumbar area. Then, the subjects were asked to perform Maximum Voluntary Contractions (MVCs) using the digital back muscle dynamometer in three different postures: (1) 0o (sagittally symmetric); (2) 30o from the mid-sagittal plane (clockwise); and (3) 30o from the mid-sagittal plane (counterclockwise). In addition to the experimental data, subject-dependent variables including Body Mass Index (BMI), percentage of body fat and muscle mass of left/right arms and legs were employed to reveal the cause of difference among three MVC conditions. All those variables were tested using statistical methods.

• Korean Journal of Radiology
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• v.25 no.3
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• pp.277-288
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• 2024

Objective: We previously found that the incidence of sarcopenia increased with declining glucose metabolism of muscle in patients with treatment-naïve diffuse large B-cell lymphoma (DLBCL). This study aimed to investigate the relationship between sarcopenia and muscle glucometabolism using ¹⁸F-FDG PET/CT at baseline and end-of-treatment, analyze the changes in these parameters through treatment, and assess their prognostic values. Materials and Methods: The records of 103 patients with DLBCL (median 54 years [range, 21-76]; male:female, 50:53) were retrospectively reviewed. Skeletal muscle area at the third lumbar vertebral (L3) level was measured, and skeletal muscle index (SMI) was calculated to determine sarcopenia, defined as SMI < 44.77 cm²/m² and < 32.50 cm²/m² for male and female, respectively. Glucometabolic parameters of the psoas major muscle, including maximum standardized uptake value (SUVmax) and mean standardized uptake value (SUVmean), were measured at L3 as well. Their changes across treatment were also calculated as ΔSMI, ΔSUVmax, and ΔSUVmean; Δbody mass index was also calculated. Associations between SMI and the metabolic parameters were analyzed, and their associations with progression-free survival (PFS) and overall survival (OS) were identified. Results: The incidence of sarcopenia was 29.1% and 36.9% before and after treatment, respectively. SMI (P = 0.004) was lower, and sarcopenia was more frequent (P = 0.011) at end-of-treatment than at baseline. The SUVmax and SUVmean of muscle were lower (P < 0.001) in sarcopenia than in non-sarcopenia at both baseline and end-of-treatment. ΔSMI was positively correlated with ΔSUVmax of muscle (P = 0.022). Multivariable Cox regression analysis showed that sarcopenia at end-of-treatment was independently negatively associated with PFS (adjusted hazard ratio [95% confidence interval], 2.469 [1.022-5.965]), while sarcopenia at baseline was independently negatively associated with OS (5.051 [1.453-17.562]). Conclusion: Sarcopenic patients had lower muscle glucometabolism, and the muscular and metabolic changes across treatment were positively correlated. Sarcopenia at baseline and end-of-treatment was negatively associated with the prognosis of DLBCL.

• Korean Journal of Veterinary Research
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• v.34 no.3
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• pp.435-439
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• 1994

The present observation was focussed mainly on the histopathological and immunohistochemical finding of the tumor developing from the outside of rat uterus wall. In gross finding, this tumor were a oval form mass and 0.75cm and 1cm in greatest demension. The sectioned surface showed uniform, solid, gray-white. In histopathological finding, the tumor showed the form of lymphoid nodule-like structure and was composed of the cells with karryorrhexis, karyolysis and necrosis in the central zone, mature cells in the paracentral zone, and concentric layers of compressed, flattened and atrophied smooth muscle fibers by the proliferating of the cells closely resembling endometrial stromal ells in the peripheral zone and a few smaller nodule-like structure in certain areas of the peripheral zone. In immunohistochemical observations, the proliferating cells presents only among the concentric layers of the smooth muscle fibers in the peripheral zone. Labeling index of proliferating cells in the peripheral zone was $4.34{\pm}1.28%$. These tumor cells did not metastasized in another orgns and labeling index was low, So it was concluded that this tumor was benign stomal sarcoma.

• Journal of The Korean Society of Integrative Medicine
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• v.10 no.2
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• pp.37-47
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• 2022

Purpose : We aimed to investigate the effects of nutritional foods on sarcopenia prevention and physical function among the elderly living in rural communities during the COVID-19 pandemic by providing customized nutrition. Methods : This study was conducted in the rural community of SCC. Participants (n=24, over age 65) were randomly assigned into a Protein group (n=12) and a Vitamin group (n=12). The protein group was given 23 g/d of protein (whey, soybean, BCAA) for 8 weeks and the Vitamin group 23 g/d of vitamin (B, C, D, E and mixed minerals such as calcium, magnesium, zinc) for 8 weeks. All participants had their body composition such as height, weight, skeletal muscle mass, body mass index, and body fat percentage, measured using bioelectrical impedance analysis (BIA) and physical function assessed using grip strength and the short physical performance battery (SPPB). Results : At the end of the intervention, there was a significant increase in skeletal muscle mass (p<.01) in the Protein group (p=.002, 4.92 %) compared to the baseline: it increased by 2.33 %. The Vitamin group had a significant increase in body fat percentage after the intervention (p=.001, 15.35 %) compared to the baseline: body fat percentage decreased by 4.49 %. There were no significant differences in left and right Grip strength/Weight, SPPB, 4-m gait speed, chair stand test, and sense of balance in both groups. Conclusion : The findings from this study suggest that 8 weeks of protein intake have a significant effect on skeletal muscle mass and body fat percentage. Protein intake helped promoting the health of the elderly in rural community during the COVID-19 pandemic. It will assist creating a foundation for providing customized nutrition for the elderly in rural community in the future.

• Journal of Korean Medicine for Obesity Research
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• v.18 no.2
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• pp.152-158
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• 2018

The purpose of this study was to investigate the effects of modified fasting therapy using Gamrosu and herbal medicine on the changes of body compositions in women. We analyzed the medical records of 11 patients, who carried out modified fasting therapy at Dunsan Korean Medicine Hospital of Daejeon University. Body compositions (body weight, body mass index, body fat mass, skeletal muscle mass, basal metabolic rate, extracellular water ratio, abdominal circumference, thickness of abdominal subcutaneous fat, visceral fat area) were reviewed before and after modified fasting therapy. The body composition values (body weight, body mass index, body fat mass, skeletal muscle mass, basal metabolic rate, extracellular water ratio, abdominal circumference, thickness of abdominal subcutaneous fat, visceral fat area) decreased after modified fasting therapy. Results from this investigation showed that modified fasting therapy using Gamrosu and herbal medicine has positive effects on changes of body compositions.

• Journal of the Korean Society of School Health
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• v.33 no.3
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• pp.203-212
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• 2020

Purpose: The purpose of this study was to investigate the relationship between relative handgrip strength (HGS/BMI) and obesity (BMI above 95th percentile) in adolescents. Methods: The subjects of the study were 637 out of 701 adolescents aged 10~18 who participated in the 2018 National Health and Nutrition Survey (KNHANES), excluding those with missing values in body mass index (BMI) and handgrip strength (HGS). The relative handgrip strength (HGS/BMI) value was divided by quartile and composite sample logistic regression analysis was performed to see its relationship with obesity (BMI above 95th percentile). The collected data were analyzed using SPSS 18.0. Results: As a result of analyzing HGS according to gender-specific quartiles, age, height, and weight of male adolescents increased significantly as HGS/BMI increased (p trend<.001). In addition, as HGS/BMI increased, total cholesterol, triglycerides, and HDL cholesterol decreased significantly (p trend<.001). In the case of female adolescents, age and height increased significantly as HGS/BMI increased (p trend<.001). HGS/BMI was lower in the obese group (p=.023), while total cholesterol was higher in the obese group(BMI above 95th percentile) than in the non-obese group. As a result of the composite sample logistic regression analysis, the odds ratio (OR) decreased significantly as the quartile increased in both male and female adolescents. Conclusion: According to these results, a follow-up study is needed to confirm the factors affecting muscle strength of adolescents. In addition, this study intends to be used as basic data to conduct further research and to develop programs that can improve muscle strength and reduce obesity in adolescents.

• The Journal of Korean Academic Society of Nursing Education
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• v.22 no.3
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• pp.345-354
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• 2016

Purpose: The purpose of this study was to determine the effects of a low intensity exercise program with telephone coaching on the physical fitness and physiological index of elderly women who are receiving home visiting health program. Methods: This study was conducted using a non-equivalent control group pretest-posttest design. The participants were 53 senior citizens. The subjects (15) in experimental group 1 performed only a low-intensity exercise program and the subjects (16) in experimental group 2 performed a low intensity exercise program with telephone coaching for 16 weeks. The low intensity exercise program consisted of muscle strength band exercise, stretching, and hand exercise using balls. Results: There were statistical differences in the right grip strength (p=.030), left grip strength (p=.035), raising behind of right arm (p=.046), raising behind of left arm (p=.045), postprandial blood sugar (p=.021), body mass index (p=.029). Conclusion: The low intensity exercise program with telephone coaching is recommended as a physical fitness and physiological index for elderly women in a home visiting health program.

• Journal of Korean Medicine Rehabilitation
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• v.18 no.4
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• pp.171-187
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• 2008

Objectives : The purpose of this study was to investigate the effects of modified fasting therapy on body composition, blood cell count and blood chemistry in inpatients. Methods : The modified fasting therapy program consists of three phases, a period of reducing food intakes, fasting and refeeding. Body weight, body composition, and the degree of obesity were estimated in before fasting therapy and after refeeding. Blood cell count and blood chemistry were estimated in before fasting therapy, before refeeding and after refeeding. Results : After modified fasting therapy, body weight, body fat mass, percent body fat, body mass index(BMI), body matabolic rate(BMR) and muscle mass was decreased significantly. WBC count and platelet count decreased significantly, RBC count and hemoglobin increased significantly and hematocrit was not changed significantly but within normal limit. AST and ALT increased significantly, especially patients group over BMI 25 within normal liver function. This study was not founded correlation between decreased muscle mass and increased liver function test. ALP, BUN, Total-cholesterol, and triglyceride decreased significantly. Creatinine increased significantly, but within normal limit. Sodium was not changed significantly, potassium decreased significantly but within normal limit. Conclusions : These results suggest that modified fasting therapy will be beneficial if several measures complement.

• Korean Journal of Community Nutrition
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• v.29 no.3
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• pp.212-221
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• 2024

Objectives: Metabolic disease is strongly associated with future insulin resistance, and its prevalence is increasing worldwide. Thus, identifying early biomarkers of metabolic-related disease based on serum profiling is useful to control future metabolic disease. Our study aimed to assess the association of serum branched chain amino acids (BCAAs) and aromatic amino acids (AAAs) ratio and metabolic disease according to body mass index (BMI) status among Korean adults. Methods: This cross-sectional study included 78 adults aged 20-59 years in Korea. We compared serum amino acid (AA) levels between adults with normal-weight and adults with obesity and investigated biomarkers of metabolic disease. We examined serum AA levels, blood profile, and body composition. We also evaluated the association between serum AAs and metabolic-related disease. Results: The height, weight, BMI, waist circumference, hip circumference, waist-hip-ratio, body fat mass, body fat percent, skeletal muscle mass, systolic blood pressure, and diastolic blood pressure were higher in the group with obesity compared to normal weight group. The group with obesity showed significantly higher levels of BCAA, AAA, and BCAA and AAA ratio. Further, BCAA and AAA ratio were significantly positively correlated with triglyceride, body weight, and skeletal muscle mass. The evaluation of metabolic disease risks revealed an association between the ratios of BCAAs and AAAs, hypertension, and metabolic syndrome. Conclusions: Our study is showed the associations between BCAA and AAA ratio, obesity, and obesity-related diseases using various analytical approaches. The elevated BCAA and AAA ratio could be early biomarkers for predicting future metabolic diseases in Korean population.