• The Korean Journal of Physiology
• /
• v.4 no.2
• /
• pp.19-24
• /
• 1970

Since the discovery of the muscle spindle by Hassall (1831), an intensive studies of its anatomical and physiological characteristics had been undertaken. Recent morphological studies of Boyd (1962) demonstrated that the muscle spindles have two different intrafusal muscle fibers, nuclear bag and nuclear chain fiber, and these intrafusal fibers are under independent motor innervation by ${\gamma}_1$ and ${\gamma}_2$ motor neurone. Neurophysiological studies of Hunt and Kuffler (1951) showed regulatory effect of ${\gamma}$ motor neurone upon the excitability of the spindle afferents. Harvey and Mathews (1961) observed the dynamic and static characteristics of the two different spindle afferents, the primary and secondary ending. Furthermore, Mathews (1962) postulated the functional existance of two kind of ${\gamma}$ motor neurones, namely, the dynamic and static fusimotor fiber. Recent report of Kim and Partridge(1969) pointed out that the descending vestibular signals had increased the slope of the length-tension relationship in stretch reflex; Kim (1967) demonstrated that the descending vestibular impulses act upon the stretch reflex loop through the ${\gamma}$ motor pathway. These experimental evidences from the morphological and neurophysiological studies on the muscle spindles support the concept that the stretch reflex action of the skeletal muscle operates as a negative feedback control system. The author had discussed the way by which the f system participates in the control of stretch relfex feed back system. that was taken for a prototype of posture and movement.

• The Korean Journal of Emergency Medical Services
• /
• v.24 no.3
• /
• pp.79-87
• /
• 2020

Purpose: This study sought to determine how the act of performing cardiopulmonary resuscitation (CPR) affects the rescuer's muscle tone, stiffness, and fatigue in the lumbar region. Methods: The research subjects were 30 healthy men in their twenties in possession of a Basic Life Support (BLS) provider certificate. In this study, the CPR rescuer's muscle tone and stiffness in the upper and lower lumbar regions were measured in the resting position, starting position, and position after 10 min. Their level of fatigue was measured before and after performing CPR. Results: Muscle tone and stiffness in the upper and lower lumbar regions of the research subjects significantly increased throughout the CPR process and lasted up to 10 min after the process (p<.001). The subjects' fatigue also significantly increased post-CPR (p<.001). Conclusion: This study suggests that performing CPR creates muscular and physiological stress, fatigue, and ultimately, lower back pain.

• The Journal of Korean Academy of Orthopedic Manual Physical Therapy
• /
• v.27 no.1
• /
• pp.13-20
• /
• 2021

Background: The serratus anterior and upper trapezius muscles act synergistically to allow for an appropriate scapulothoracic rhythm. However, a decrease in serratus anterior activation causes the upper trapezius to become overactivated, resulting in dysfunction. This study compared serratus anterior and upper trapezius muscle activity according to sling angle and compared serratus anterior strength between healthy adults and patients with shoulder instability. Methods: Twenty participants (10 healthy adults and 10 patients with shoulder instability) were included in this study. The participants had their arms extended at sling angles of 30°, 60°, and 90° in reach forward with shoulder flexion using goniometer. Serratus anterior strength was measured three times while the participants were supine. The outcome measures were surface electromyography amplitude of the upper trapezius and serratus anterior and serratus anterior strength. Results: The Wilcoxon signed-rank test indicated that the upper trapezius was significantly different between healthy group and shoulder instability group at a sling angle of 60°, and both the upper trapezius and serratus anterior exhibited significant differences at 90°. Moreover, a significant difference was noted in the muscle strength of the serratus anterior. Conclusion: Our results provide novel and promising clinical evidence that patients with shoulder instability have decreased serratus anterior activation and upper trapezius overactivation, resulting in muscle imbalance. In addition, there was a significant difference between the healthy group and shoulder instability group in the serratus anterior muscle strength

• Journal of Ginseng Research
• /
• v.34 no.2
• /
• pp.145-149
• /
• 2010

This study investigated the antioxidant effects of ginseng coffee in L6 muscle cells. Ginseng coffee was prepared by coating and digesting coffee beans with ginseng concentrate. The ginseng coffee water extract potently protected against hydrogen peroxide-induced L6 cell death and adenosine triphosphate reduction in a dose-dependent manner; in fact, these cytoprotective effects were significantly greater than those of normal coffee. However, ginseng coffee did not exhibit significant radical scavenging or catalase-like activity. These results suggest that ginseng coffee might act as a cytoprotective agent in muscles, but that the protective effects are not due to a direct radical-reduction property but rather to another intracellular signaling factor.

• The Journal of Pediatrics of Korean Medicine
• /
• v.14 no.2
• /
• pp.85-96
• /
• 2000

Objectives : This experimental study was designed to investigate the effects of hormone changes in the rats with muscle atrophy in response to Strychnos nuxvonica L. Methods : 24 male rats with muscle atropht by hindlimb suspension method as experimental group and 6 normal male rats were used. Experimental group was administered Strychnos nuxvonica L. 3 times a day, 1mg/kg per one dosage P,O, After 2 to 4 weeks hormone changes in blood were analysed. Results and Conclusions : Norepinephrine and Epinephrine level in blood as they act neurotransmitting substances were significantly increased by administering Strychnos nuxvonica L.

• Transactions of the Korean Society of Mechanical Engineers
• /
• v.15 no.6
• /
• pp.1967-1974
• /
• 1991

When the functional electrical stimulation is employed to recover mobility to the plegic, it is very important to understand functions of the selected muscles. I have investigated how a muscle acts to accelerate the body segments, since the body segements are connected by joints so that contraction of a muscle not only rotates the segments to which it is attached but also causes other segments to rotate by creation a reaction force at every joint, which is called the inertial coupling. I found that a single-joint muscle always acts to accelerate the spanned joint in the same direction as the joint torque produced by the muscle. However, a double-joint muscle can act to accelerate the spanned joint in the opposite direction to the joint torque produced by the muscle depending on (1) the body position, (2) the body-segmental parameters, and (3) the type of the movement. Investigating the condition number of the inertia matrix of the body-segmental model gave us some insights into how controllable the body-segmental system is for different values of the factors mentioned above. The results suggested that the upright position is the most undesirable position to independently control the three segments(trunk, thigh and shank) and that the controllability is the most sensitive to variation of the shank length and the trunk mass, which implies that accuracy is required particularly when we estimate these two body-segmental parameters before the paralyzed muscles are innervated by using electrical stimulation.

• Proceedings of the KOR-BRONCHOESO Conference
• /
• 1982.05a
• /
• pp.16.1-16
• /
• 1982

The lips play an important role of passage of food as well as articulation and production of intelligible speech. So, the orbicularis oris muscle which composes the lip must act as a sphincter for the right structure. Also, the muscle conforms to the shape of the lips to make words. The surrounding cheek muscles antagonize and synergize to position the orbicularis oris sphincter. It is highly significant from the standpoint of reconstruction that the surrounding muscle can be separated from the orbicularis oris muscle without loss of sphincteric competence as long as the facial nerves and vessels remain intact. The authors performed the reconstruction of a lower lip defect due to human bite and achieved an excellent result from a functional and cosmetic aspect. This report with the literature is herewith submitted.

• Journal of Korean Physical Therapy Science
• /
• v.9 no.4
• /
• pp.177-184
• /
• 2002

The knee joint is composed of 3 skeletons that is the femoral bone, the tibial bone, and the patella bone. The tibiofemoral pint and patellofemoral pint act with the meniscus, so these function that is maintain the stabilities by the surrounding soft tissue is complex. The protection mechanism(muscle tension) of the surrounding muscles for the joint disease(Arthritis) limits consistently the motion of the pint to decrease the internal pressure of the joint, and these muscle tension acts with abnormal function for the surrounding tissue and the joint, sometimes the contracture is developed, if the joint with disease is not recovery or treated within early time. So we worked out efficient orthopedic local taping for the patient who is complained of the knee pint pain using the literature investigation about the anatomical structure and the biomechanics of the knee pint for the muscle and the pint problem esp, the rotation of the tibia, the dislocation of the patella, and the motion of the meniscus that is developed due to tension of surrounding muscles of the knee pint. And application of the pint mobilization, the stretching, and the muscle strengthening exercise for the pint will become successful treatment for the joint disease.

• Physical Therapy Korea
• /
• v.19 no.3
• /
• pp.105-114
• /
• 2012

This study was performed to compare the muscle activity of lumbar stabilizers between stoop and semi-squat lifting techniques at different lifting loads. Twenty healthy subjects (9 males, 11 females) were recruited for this study. Muscle activity of external obliques (EO), internal obliques (IO) and lumbar multifidus (LM) muscle was measured by surface electromyography during stoop and semi-squat lifting at different lifting loads (10%, 20%, and 30% of the subject's body weight). A one-way repeated measure ANOVA was applied. The results showed that EMG activity of EO was significantly increased with a load of 30% of body weight compared to 10% and 20% of body weight in both lifting techniques (p<.05). Muscle activity of LM was significantly increased in 20% compared to 10% and 30% compared to 10% of subject's body weight in stoop lifting and the muscle activity of LM was significantly increased in 20% compared to 10%, 30% compared to 20%, and 30% compared to 10% of the subject's body weight in semi-squat lifting (p<.05). However, there was no significant difference in activity of IO according to lifting loads in both lifting techniques. There were no significant differences in muscle activity of EO, IO, and LM between stoop and semi-squat technique (p>.05). Therefore, the results of this study suggested that the EO can contribute to increase the lumbar stability during stoop and semi-squat lifting at 30% of body weight rather than at lower loads, and the LM seems to act as counteractor to imposed loads during stoop and semi-squat lifting with increasing loads.

• Biomedical Science Letters
• /
• v.10 no.1
• /
• pp.23-29
• /
• 2004

Nebulin is a (Mr 600∼900 kDa) large actin-binding protein specific to skeletal muscle and thought to act as a molecular template that regulates the length of thin filaments. Cardiac muscles of higher vertebrates have been shown earlier to lack nebulin. Recently, full-length nebulin mRNA transcripts have been detected in heart muscle, but at lower levels than in skeletal muscle. Nebulin expression also was detected in the kidney, eye, and otic canal, suggesting that nebulin isoforms may also be expressed in these organs. We have searched for nebulin isoforms in brain of human using PCR and Northern blot. Here, we provide evidence that nebulin mRNA transcripts are expressed in brain. Seven nebulin isoforms (B, C, D, E, F, G and H form) are obtained in human skeletal muscle and four isoforms (B, C, G and H form) in human brain cDNA library. We cloned the 1.3 kb of nebulin fragment from human adult brain library by PCR. The identity of the PCR product was confirmed by sequence analysis. The partial brain nebulin sequence was 99% identical to the skeletal muscle cDNA as determined by Blast alignment. It contains two simple-repeats HR1, HR2 and linker-repeats exon l35∼143 except exon 140. It was different from skeletal muscle B form, which contain HR1 and HR8. These data suggest that nebulin isoform diversity occurs even more extensively than previously known, likely contributing to the distinct thin filament architecture of different striated muscles.