• 제목/요약/키워드: Mumps

검색결과 68건 처리시간 0.026초

중고등학생의 볼거리 전파관리 현황과 불현성 감염률: 2007-2008 대구 볼거리 유행을 중심으로 (Mumps Transmission Control Status and Inapparent Infection Rate among Middle and High School Students during the 2007-2008 Mumps Outbreak in Daegu)

  • 김교현;김창휘;최보율;고운영;이동한;기모란
    • Journal of Preventive Medicine and Public Health
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    • 제42권6호
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    • pp.408-415
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    • 2009
  • Objectives : This study was performed to investigate the mumps transmission control status and inapparent infection rate among middle and high school students in Daegu City during a mumps outbreak. Methods : Nine schools (two middle schools and seven high schools), which reported a number of mumps cases between 2007 and 2008 were selected for investigation. During March-May 2008, a standard questionnaire was distributed to gather information about case identification, instructed isolation measure, isolation status of mumps cases and related factors, and outdoor activities of nonisolated mumps case. Inapparent infection rate was estimated by serum mumps IgM and IgG antibodies status and self-reported mumps symptoms in three of the nine schools. Results : Among 2,560 respondents, more than half of students answered that they did not receive instructions in mumps transmission control measures during the outbreak. Among the 327 mumps cases identified by the questionnaire, 131 cases (40.1%) were considered as isolated and the isolation rates were significantly different among schools, grades, and gender. Of the non-isolated cases, 88.3% continued attending school. Inapparent mumps infection rates were between 56.3% and 70.2%. Conclusions : Mumps transmission control was inadequate to control the mumps outbreak. Although high inapparent infection rate would mitigate the transmission control effect of case isolation, this measure is fundamental for infection control. The reasons of this inadequate status need to be explored to develop an effective intervention strategy.

유행성 이하선염의 치료법에 관한 문헌고찰 - 중의학 저널을 중심으로 - (A Literature Study about Treatment of Epidemic Mumps in Children - Based on Traditional Chinese Medical Journal -)

  • 성현경
    • 대한한방소아과학회지
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    • 제27권2호
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    • pp.48-69
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    • 2013
  • Objectives There are constant increase numbers of cases mumps in children. The purpose of this study is to analyze traditional Chinese medicine treatments of epidemic mumps in children through traditional Chinese medical journal research. Methods 20 studies were selected based on title keyword "Epidemic mumps" "Child" published in CAJ(China Academic Journal). Study researched about clinical effect, herbs, attachment, moxa, venesection treatments in epidemic mumps in children Results & Conclusions There are so many treatments about epidemic mumps in children through analyzing studies in CAJ. Single and combination traditional Chinese medicine treatment is more effective in epidemic mumps in children. Therefore, we need to study more about epidemic mumps in children and should make more clinical case about it.

볼거리 고환염에 따른 무정자증: 2례 (Azoospermia Following Mumps Orchitis:2 Case)

  • 심현선
    • 한국콘텐츠학회논문지
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    • 제16권11호
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    • pp.767-775
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    • 2016
  • 볼거리(mumps)는 타액선을 비롯한 전신에 침범하는 급성 바이러스성 염증 질환으로 일측성 또는 양측성 이하선의 종창과 통증을 동반한다. 볼거리 바이러스는 공기, 타액, 소변으로 다른 사람들에게 전파 되고, 학교, 군대 등 인구밀도가 높은 집단에서 발생하며 양측 고환에 침범하는 경우는 10-60% 정도이다. 사춘기 이후에 남성 볼거리 고환염(mumps orchitis)에 이완되는 경우 1-2개월 후에 감염자의 50%에서 심한 고환 위축과 같은 합병증이 발생한다. 볼거리 고환염은 정자 수, 형태, 운동성 등에 영향을 미치고 정자감소증과 드물게 무정자증으로 인한 불임이 발생한다. 볼거리 고환염이 의심되는 경우 초기 대증적 치료를 적극적으로 함으로써 장차 성인이 되었을 때 무정자증으로 인한 불임을 예방할 수 있을 것으로 생각된다. 본 증례에서는 볼거리 고환염을 앓은 후 무정자증을 보인 2례를 경험하였기에 초음파검사와 정액검사에 대해 참고문헌과 함께 보고하고자 한다.

MMR 2차 예방접종을 받은 후 이하선염 없이 발생한 볼거리 뇌염 1례 (Mumps meningoencephalitis without parotitis, after secondary vaccination of Measles-Mumps-Rubella (MMR) : A Case Report)

  • 최판규;강현구
    • 한국산학기술학회논문지
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    • 제18권9호
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    • pp.123-126
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    • 2017
  • 볼거리(mumps)는 유행선 이하선염(epidemic parotitis)으로 불리며, 볼거리 바이러스에 의해 유발되는 바이러스성 감염질환이다. 볼거리는 췌장염, 고환염, 청력장애, 난소염, 이하선염 및 뇌수막염과 같은 합병증을 일으킬 수 있다. 볼거리로 인한 중추신경계의 침범은 볼거리로 진단된 환자의 65%에 달한다는 보고가 있으며, 그 중 대부분은 볼거리 뇌막염(mumps meningitis)이다. 이에 반해 볼거리 뇌염(mumps meningoencephalitis)은 볼거리 환자 6000명당 1명의 경우로 매우 드물다고 알려져 있다. 뇌염은 볼거리바이러스의 흔하지 않은 중추신경계의 합병증으로 홍역-볼거리-풍진 예방접종은 볼거리바이러스로 인한 치명적인 합병증을 예방해주고 경과를 가볍게 해준다고 알려져 있다. 저자들은 24세의 젊은 여자가 이하선염을 동반하지 않은 볼거리 바이러스로 인한 급성 뇌염을 경험하여 이에 대한 사례 연구를 하였다. 환자는 예방접종 시기에 맞춰 볼거리 예방접종을 받았다. 본 병원을 내원 시 환자는 인지능력의 저하를 보였으며 치료 후 빠른 회복을 보였고 합병증은 보이지 않았다. 이 연구는 볼거리 바이러스에 대한 2차 접종을 시기에 맞춰 받은 환자에서 이하선염의 동반 없이 뇌염증상이 발생한 환자에 대한 사례 연구이다.

Outbreaks of mumps: an observational study over two decades in a single hospital in Korea

  • Ryu, Ji-Ung;Kim, Eun-Kyung;Youn, You-Sook;Rhim, Jung-Woo;Lee, Kyung-Yil
    • Clinical and Experimental Pediatrics
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    • 제57권9호
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    • pp.396-402
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    • 2014
  • Purpose: The introduction of the mumps vaccine has dramatically reduced the number of mumps cases, but outbreaks have recently occurred among highly vaccinated populations in developed countries. Epidemiological and clinical characteristics of patients with mumps admitted between 1989 and 2012 in a single hospital in Korea are described in the present study. Methods: We retrospectively evaluated inpatients with mumps between 1989 and 2012 and outpatients and inpatients with mumps in 2011-2012. Results: A total of 152 patients with mumps were admitted between 1989 and 2012, and 163 patients were recorded in 2011-2012. The highest number of admitted cases occurred in 1998 and 2012 (35 and 34 cases, respectively). Among the patients admitted in 2011-2012, the highest frequency was observed among people aged 15-19 years, and low frequency was observed in those aged <4 years and >20 years, compatible to the city data and national data. In patients admitted to our department in 1998 (35 cases) and in 2010-2012 (27 cases), there were significant differences in the mean age and the rate of secondary measles-mumps-rubella (MMR) vaccination, but had similar clinical features, including complications, except aseptic meningitis. Antimumps immunoglobulin (Ig) G was positive in 83% and 100%, and IgM was positive in 67% and 41%, respectively, in the two periods. Conclusion: In Korea, recent mumps outbreaks have occurred mainly among secondary school students who received two doses of the MMR vaccine. The vaccinees might have a modified immune reaction to viral insults, manifesting modified epidemiological and clinical features.

한국 소아의 Mumps 바이러스 항체보유에 관한 혈청학적 진단방법의 비교 (A Comparative Study of Serologic Methods for Detection of Mumps Antibody in Korean Children)

  • 박혜경
    • 대한미생물학회지
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    • 제21권4호
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    • pp.473-480
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    • 1986
  • Mumps is an extremly common infectious disease affecting predominantly young children hut it is not a severe disease in terms of mortality. One hundred and two sera from infants of 3 different groups which are vaccinated, unvaccinated and unknown were detected to mumps antibody. The tests used were Complement Fixation(CF) test, Single Radial Hemolysis(SRH) test, Hemagglutination Inhibition(HI) test, Enzyme Linked Immunosorbent Immunoglobulin G(ELISA IgG) test, Enzyme Linked Immunosorbent Immunoglobulin M(ELISA IgM) test. 1. The rate of positivity for mumps antibody in 102 sera wera 89.16%(74/83) by Hl test, 68.83%(53/77) by ELISA IgG test, 64.58%(62/96) by SRH test, 63.24%(43/68) by ELISA IgM test and 50.00%(49/98) by CF test. 2. The rate of positivity by 5 tests for 55 sera turned out to be very similar with above results respectively. 3. The correlation coefficients(r) between ELISA IgG test ant H1 test, ELISA IgG test and ELISA IgM test were 0.34(P<0.0l) and 0.31(P<0.02), respectively. 4. The percentage of apparently natural infection of mumps seemed to be 65.15%(43/66) in infants. 5. Seroconversion rate of mumps by vaccination were 90.91%(10/11). 6. Among the 53 infants who were tested with ELISA IgG 15 were below 15 months age of(28.30%) and this percentage may be taken as a suggestion that mumps vaccination should be given earlier than present practice. 7. ELISA IgG test was found very sensitive and recommendable method for large scale screening for the presence of antibody to mumps.

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Factors associated with mumps meningitis and the possible impact of vaccination

  • Rhie, Kyuyol;Park, Heung-Keun;Kim, Young-Soo;Yeom, Jung Sook;Park, Ji Sook;Seo, Ji-Hyun;Park, Eun Sil;Lim, Jae-Young;Park, Chan-Hoo;Woo, Hyang-Ok;Youn, Hee-Shang
    • Clinical and Experimental Pediatrics
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    • 제59권1호
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    • pp.24-29
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    • 2016
  • Purpose: Mumps meningitis is a common complication of mumps infection; however, information on mumps meningitis in the postvaccine era is limited. The purpose of the present study was to determine factors associated with mumps meningitis and to discuss the effect of vaccination on this disease. Methods: We retrospectively reviewed patients younger than 19 years with mumps, diagnosed at a university hospital in Korea between 2003 and 2013. Patients were divided into groups with and without meningitis, and the clinical features of the 2 groups were compared. Results: The study enrolled 119 patients: 19 patients with meningitis and 100 patients without. Univariate analysis showed that older age (median: 15 years vs. 9.5 years, respectively), a longer interval from last vaccination (median: 10.2 years vs. 4.8 years, respectively), and febrile presentation (94.7% vs. 31.0%, respectively) were significantly associated with mumps meningitis. Sex, number of vaccination doses, bilateral parotitis, and the presence of complications other than meningitis did not differ between the 2 groups. In multivariate logistic regression analysis, age (odds ratio, 1.38; 95% confidence interval, 1.01-1.89; P=0.04) and fever (odds ratio, 30.46; 95% confidence interval, 3.27-283.61; P<0.01) remained independent factors for mumps meningitis. Conclusion: Clinicians in the postvaccine era should be aware of the possibility of mumps meningitis in febrile cases of mumps in adolescents, regardless of the number of vaccination doses. To establish the role of vaccination in mumps meningitis, further studies will be necessary.

한국에서 분리된 유행성이하선염 바이러스 변이에 관한 연구 (Study on Variation of Endemic Mumps Viruses in Korea)

  • 민경일;김도근;조수열;안광수;민복순;김병국;반상자;허숙진;박순희;이길웅
    • 대한바이러스학회지
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    • 제30권2호
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    • pp.113-124
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    • 2000
  • We had isolated 8 viruses from 91 specimen collected at southwest Cheju Province during early spring 1998 and 2 viruses from 9 specimen collected at Chung Nam Province during early spring 1999. To perform cross-reactivity among 4 mumps vaccine strains and 10 wild-type mumps viruse isolates, we immunized mice and took antisera against each virus. There were no antibody titer differences by indirect immunofluorescence assay (IFA), but most isolated mumps viruses showed a little cross-reactivities with Jeryl Lynn and Rubini strains. It has shown similar result by haemagglutination-inhibition (HAI) test. These results show that 4 mumps strains used as vaccine have the protection ability against endemic wild-type mumps viruses. Also the SH gene analysis was performed to identify genotypes. Most isolated mumps viruses belonged to genotype D. These results indicate that endemic mumps viruses in Korea are different to ones isolated in Japan and China.

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다시 출현하는 감염병: 홍역, 볼거리, 풍진, 백일해의 진단을 중심으로 (Reemerging Old Infectious Diseases: Diagnosis of Measles, Mumps, Rubella, and Pertussis)

  • 김경효
    • Pediatric Infection and Vaccine
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    • 제20권3호
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    • pp.115-122
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    • 2013
  • Reemerging infectious diseases are infections that had decreased in incidence in the global population and were brought under control through effective health care policy such as vaccination, but more recently, began to resurge as a health problem due to many reasons. Measles, rubella, mumps and pertussis are the examples. Immunization with MMR (measles, mumps, rubella) and pertussis vaccine has contributed to marked decrease in measles, mumps, rubella and pertussis incidence worldwide. In Korea, measles and rubella almost disappeared after the introduction of 2 doses of MMR immunization schedule. Recently, these infections have been reemerging in many countries with low vaccination rates and can be introduced again in Korea. However mumps and pertussis outbreaks are reported among fully vaccinated populations. Declining vaccine effectiveness, an increased awareness and surveillance of the disease or improved laboratory diagnostic tools had been suggested as possible causes. For the clinicians, it is difficult to diagnose these reemerging infectious diseases partly because of few experience of typical cases of measles and rubella or partly because of modification of clinical symptoms and signs of infectious diseases in immunized population. In this article, the diagnosis of measles, mumps, rubella and pertussis will be reviewed in the aspects of clinical characteristics, serologic methods, virus isolation, and polymerase chain reaction.

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트리형 데이터베이스 및 언어 MUMPS 활용 (Study on Tree-Structured Database and Language MUMPS)

  • 임지현;김진덕
    • 한국정보통신학회:학술대회논문집
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    • 한국정보통신학회 2019년도 춘계학술대회
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    • pp.108-110
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    • 2019
  • 데이터베이스(Database)란 중복이 없는 데이터의 집합을 유지하는 것을 말하며, 정보의 양이 증가하고 있는 정보화 사회에서 정보를 쉽게 이용하고 공유하기 위해서 필수적이다. 데이터베이스의 대표적인 구조는 관계형 데이터베이스와 트리구조 데이터베이스가 존재하며, 본 연구에서는 트리구조 데이터베이스이자 프로그래밍 언어인 MUMPS에 대해 연구하고자 한다. 이 언어는 동적 또는 B-Tree 형식으로 배열을 저장하여 데이터베이스를 구성한다. Java나 C#과 같은 언어와 함께 사용하여야 하는 SQL과 달리, MUMPS는 자체적으로 언어와 데이터베이스를 지원하여 데이터를 관리할 수 있다는 차이점이 있으며, 데이터 이식률이 높아 실제 미국 병원에서는 MUMPS 기반의 플랫폼이 높은 시장 점유율을 차지하고 있다.

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