• Journal of Ginseng Research
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• 제41권3호
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• pp.379-385
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• 2017

In this study, white ginseng was used as the raw material, which was fermented with Paecilomyces hepiali through solid culture medium, to produce ginsenosides with modified chemical composition. The characteristic chemical markers of the products thus produced were investigated using rapid resolution liquid chromatography coupled with quadrupole time-of-flight mass spectrometry (RRLC-QTOF-MS). Chemical profiling data were obtained, which were then subjected to multivariate statistical analysis for the systematic comparison of active ingredients in white ginseng and fermented ginseng to understand the beneficial properties of ginsenoside metabolites. In addition, the effects of these components on biological activity were investigated to understand the improvements in the phagocytic function of macrophages in zebrafish. According to the established RRLC-QTOF-MS chemical profiling, the contents in ginsenosides of high molecular weight, especially malonylated protopanaxadiol ginsenosides, were slightly reduced due to the fermentation, which were hydrolyzed into rare and minor ginsenosides. Moreover, the facilitation of macrophage phagocytic function in zebrafish following treatment with different ginseng extracts confirmed that the fermented ginseng is superior to white ginseng. Our results prove that there is a profound change in chemical constituents of ginsenosides during the fermentation process, which has a significant effect on the biological activity of these compounds.

• 한국컴퓨터그래픽스학회논문지
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• 제23권4호
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• pp.21-29
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• 2017

예측 시각적 분석 연구는 다양한 대화식 데이터 탐색 기법을 사용하여 예측 결과의 불확실성을 줄이는데 중점을 두었다. 대화식 탐색 기법의 목적은 변수간의 관계를 이해하고 알려지지 않은 변수를 예측하기 위한 적합한 모델을 선택함으로서 의사결정권자의 수준에 따른 예측결과의 품질 차이를 줄이는 것이다. 하지만 청소년 신체 성장 데이터와 같이 전체적인 추세가 알려지지 않은 시계열 데이터를 설명할 수 있는 예측 모델을 만드는 것은 어렵다. 본 논문에서는 불확실한 추세를 가지는 시계열 데이터 단편에서 물리적 성장 값을 예측하기 위한 새로운 예측 방법을 제안한다. 새로운 예측 방법은 특정 시점에서의 데이터 분포를 추정하는 방법으로 실험결과 기존 회귀 모델보다 높은 정확도를 갖는다. 또한 우리는 예측 모델링 과정에서 발생 가능한 불확실성을 최소화 할 수 있는 시각적 분석 방법을 제안한다.

• 한국환경보건학회지
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• 제26권2호
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• pp.34-40
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• 2000

The purpose of this study was to investigate the seasonal variation of PAHs and to estimate their source characteristics in Taegu area. To do this, four sampling sites were selected to represent an industrial, a traffic, a traffic & residential, and a residential area in Taegu. Total of 72 samples had been collected from January, 1999 to September, 1999 on glass micro fiber filters by high volume air sampler. The PAHs in the total suspended particulate were extracted by a soxhlet process with dichloromethane and analyzed by GC/MSD, GC/FID. A statistical analysis was performed for the PAHs data set using a principal component analysis to derive important factor inherent in the interactions among the variables. The specific conclusions of this research are: 1) There was a significant seasonal and local variation in the atmospheric concentration of PAHs. The seasonal variation is winter>spring>Fall>summer, and the local variation is industrial>traffic>graffic & residential>residential area. 2) To evaluate the correlation between a measured PAHs and other affecting factors such as air pollutant concentration and meterological data, statistical analysis was performed. PAHs and other affecting factors such as air pollutant concentration and meterological data, statistical analysis was performed. PAHs have negative correlation with temperature (r=-0.593, p<0.05), radiation(r=-0.535, p<0.05), and O3(r=-0.719, p<0.05), but have positive correlation with NO(r=0.615, p<0.05) 3)Finally, multivariate analysis was performed for the PAHs dat set to identify and to estimate the source contributions of PAHs. According to results of statistical analysis, it could be identifies as three factors such as vehicular/gasoline, vehicular/diesel, and combustion in Taegu area.

• Restorative Dentistry and Endodontics
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• 제42권2호
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• pp.95-104
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• 2017

Objectives: This study evaluated the influence of a multi-mode universal adhesive (MUA) containing silane (Single Bond Universal, 3M EPSE) on the bonding of resin cement to lithium disilicate. Materials and Methods: Thirty IPS e.max CAD specimens (Ivoclar Vivadent) were fabricated. The surfaces were treated as follows: Group A, adhesive that did not contain silane (ANS, Porcelain Bonding Resin, Bisco); Group B, silane (S) and ANS; Group C, hydrofluoric acid (HF), S, and ANS; Group D, MUA; Group E, HF and MUA. Dual-cure resin cement (NX3, Kerr) was applied and composite resin cylinders of 0.8 mm in diameter were placed on it before light polymerization. Bonded specimens were stored in water for 24 hours or underwent a 10,000 thermocycling process prior to microshear bond strength testing. The data were analyzed using multivariate analysis of variance (p < 0.05). Results: Bond strength varied significantly among the groups (p < 0.05), except for Groups A and D. Group C showed the highest initial bond strength ($27.1{\pm}6.9MPa$), followed by Group E, Group B, Group D, and Group A. Thermocycling significantly reduced bond strength in Groups B, C, and E (p < 0.05). Bond strength in Group C was the highest regardless of the storage conditions (p < 0.05). Conclusions: Surface treatment of lithium disilicate using HF and silane increased the bond strength of resin cement. However, after thermocycling, the silane in MUA did not help achieve durable bond strength between lithium disilicate and resin cement, even when HF was applied.

• Journal of the Korean Wood Science and Technology
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• 제48권5호
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• pp.591-607
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• 2020

This study was aimed to investigate the changes of chemical composition of the volatile organic compounds (VOCs) emitted from red pine needles in the process of needle abscission or senescence. The VOCs in intact, senescent, and litter red pine needle samples were analyzed by headspace-solid phase microextraction gas chromatography-mass spectrometry (HS-SPME-GC/MS). And then, multivariate statistical interpretation of the processed data sets was conducted to investigate similarities and dissimilarities of the needle samples. Principal component analysis (PCA) and orthogonal partial least squares discriminant analysis (OPLS-DA) were used to investigate the dataset structure and discrimination between samples, respectively. From the data preview, the levels of major components of VOCs from needles were not significantly different between needle samples. By PCA investigation, the data reduction according to classification based on the chlorophyll a / chlorophyll b (Ca/Cb) ratio were found to be ideal for differentiating intact, senescent, and litter needles. The following OPLS-DA taking Ca/Cb ratio as y-variables showed that needle samples were well grouped on score plot and had the significant discriminant compounds, respectively. Several compounds had significantly correlated with Ca/Cb ratio in a bivariate correlation analysis. Notably, the litter needles had a higher content of oxidized compounds than the intact needles. In summary, we found that chemical compositions of VOCs between intact, senescent, and litter needles are different each other and several compounds reflect characteristic of needle.

• 한국수자원학회논문집
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• 제38권8호
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• pp.595-604
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• 2005

관측자료의 보완이나 확충을 위한 강수량 모의발생은 수문분석에 있어서 중요한 과제라고 할 수 있다. 강수량을 모의하는 방법은 크게 기존의 매개변수적 방법과 비매개변수적 방법 두 가지로 나눌 수 있고, 강수량 모의의 시간간격에 따라 일강수량 자료의 모의 또는 시간강수량 자료의 모의 등으로 구분할 수 있다. 지금까지, Markov모형은 일강수량 모의발생에 많이 이용되어왔다. 이러한 대부분 Markov모형들은 동질성모형으로 상태벡터를 구축하는데 있어서 자료의 크기가 작으면 모형구축의 어려움이 따르고 같은 월에 대한 상태벡터의 동질성을 가정하는 등의 문제가 있다. 실제 강수발생의 과정은 비정상적(nonstationary)이므로 이를 보완하기 위해, 된 논문에서는 일강수량을 기존의 매개변수적인 방법이 아닌 단변량과 다변량에 대하여 비매개변수적인 방법으로 접근하여 모의하는 방법에 대하여 분석하였다.

• 대한원격탐사학회지
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• 제15권3호
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• pp.195-208
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• 1999

위성영상 분류작업에서 분류클래스에 대한 샘플화소의 대표성은 분류 정확도에 많은 영향을 미친다. 따라서, 통계적 영상분류방법에서는 분류 기법 자체보다 분류 확률을 결정하는 트레이닝 단계, 즉 샘플화소의 최적화가 필요하다. 본 연구에서는 SPOT XS, LANDSAT TM을 이용한 위성영상 화소분류작업에서 분류 이전단계, 즉 샘플화소의 정규성을 계산하여, 정규성에 악영향을 미치는 화소를 객관적 기준으로 조정하였다. 정규화과정을 위한 유전자 알고리즘 적용의 생존확률 평가함수로 다변량 Q-Q plot의 상관계수와 트레이닝의 분산값을 고려하였으며, 5% 유의수준을 적용하였다. 연구결과, 실험대상지역의 경우, 유전자 알고리즘을 이용한 트레이닝 정규화 결과가 대부분의 클래스에 대하여 그 평균과 분산을 모집단에 근사시키고 있다는 것을 입증하였고, 해당 클래스의 모집단 분포를 예측할 수 있는 가능성을 제시하였다.

• 대한지역사회영양학회지
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• 제26권3호
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• pp.155-166
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• 2021

Objectives: Driven by a growth of single-person households and individualized lifestyles, solo dining in restaurants is an increasingly recognizable trend. However, a research gap exists in the comparison of solo and group diners' menu-decision making processes. Based on the self-control dilemma and the temporal construal theory as a theoretical framework, this study compared the ordering intentions of solo vs. group diners with healthy vs. indulgent (less healthy) entrées. The mediating role of consumption orientation and the moderating role of amount of menu nutrition information were further explored to understand the mechanism and a boundary condition. Methods: A scenario-based online survey was developed using a 2 (dining social context: solo vs. with others) × 3 (amount of menu nutrition information: no nutrition information vs. calories vs. calories/fat/sodium), between-subjects, experimental design. Consumers' level of nutrition involvement was controlled. A nationwide survey data (n = 224) were collected from a crowdsourcing platform in the U.S. Data were analyzed using multivariate analysis of covariance, independent t-test, univariate analysis of covariance, and moderated mediation analyses. Results: Findings reveal that solo (vs. group) diners have less (vs. more) intentions to order indulgent menu items due to a more utilitarian (vs. more hedonic) consumption orientation in restaurant dining. Findings also show that solo (vs. group) diners have more (vs. less) intentions to order healthy menu items when the restaurant menu presented nutrition information including calories, fat, and sodium. Conclusions: The findings contribute to the literature of foodservice management, healthy eating, and consumer behavior by revealing a mechanism and an external stimuli of solo vs. group diners' healthy menu-decision making process in restaurants. Furthermore, the findings provide restauranteurs and health professionals with insights into the positive and negative impacts of menu nutrition labelling on consumers' menu-decisions.

• 한국엔터테인먼트산업학회논문지
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• 제14권8호
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• pp.213-219
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• 2020

본 연구는 치매의심군 8명, 치매확정군 9명 및 정상군 10명을 대상으로 명명하기 과제에서 오류 유형의 특성을 탐색하는 데 그 목적이 있다. 명명하기의 오류 분석 항목은 시지각적 오류, 의미적 연관 오류, 의미적 비연관 오류, 음소적 오류, 모름, 무반응으로 구분하여 분석하였다. 분석을 위해 SPSS 21.0을 활용하여, 기술통계분석, 분산분석, 다변량분산분석을 실시하였다. 연구결과, 오류유형에 따라 집단 간 오류율에는 유의한 차이는 있는 것으로 나타났다. 정상군이 다른 두 집단과 유의한 차이를 보인 오류는 시지각 오류와 의미적 비연관 오류이며, 무응답 오류는 치매확정군과는 차이가 있었으나, 치매의심군과는 유의한 차이가 없는 것으로 나타났다. 이러한 연구 결과, 알츠하이머성 치매 환자들이 그림 명명하기 능력에 결함이 있음을 확인하였다. 또한 정보처리과정 중 특정 단계의 퇴행으로 인한 결함이 심해지면 다른 단서를 제공하는 것이 적절하다는 것을 알 수 있었다.

• Clinics in Shoulder and Elbow
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• 제26권2호
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• pp.162-168
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• 2023

Background: Reverse shoulder arthroplasty (RSA) has evolved continuously over recent years, with expanded indications and better outcomes. YouTube is one of the most popular sources globally for health-related information available to patients. Evaluating the reliability of YouTube videos concerning RSA is important to ensure proper patient education. Methods: YouTube was queried for the term "reverse shoulder replacement." The first 50 videos were evaluated using three different scores: Journal of the American Medical Association (JAMA) benchmark criteria, the global quality score (GQS), and the reverse shoulder arthroplasty-specific score (RSAS). Multivariate linear regression analyses were conducted to determine the presence of a relationship between video characteristics and quality scores. Results: The average number of views was 64,645.78±264,160.9 per video, and the average number of likes was 414 per video. Mean JAMA, GQS, and RSAS scores were 2.32±0.64, 2.31±0.82, and 5.53±2.43, respectively. Academic centers uploaded the highest number of videos, and surgical techniques/approach videos was the most common video content. Videos with lecture content predicted higher JAMA scores whereas videos uploaded by industry predicted lower RSAS scores. Conclusions: Despite its massive popularity, YouTube videos provide a low quality of information on RSA. Introducing a new editorial review process or developing a new platform for patients' medical education may be necessary. Level of evidence: Not applicable.