• 제목/요약/키워드: Multiple-trait

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Estimation of Genetic Variance and Covariance Components for Litter Size and Litter Weight in Danish Landrace Swine Using a Multivariate Mixed Model

  • Wang, C.D.;Lee, C.
    • Asian-Australasian Journal of Animal Sciences
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    • 제12권7호
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    • pp.1015-1018
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    • 1999
  • Single trait mixed models have been dominantly utilized for genetic evaluation of the reproductive traits in swine. However employing multiple trait approach may lead to more accurate genetic evaluations. For 5 litter size and litter weight traits of Danish Landrace, genetic parameters were estimated with a multiple trait mixed model. The heritability estimates were 0.02, 0.03, 0.03, 0.05, and 0.07, respectively for litter size at birth, litter size born alive, litter weight at birth, litter size at weaning, and litter weight at weaning. Negative genetic correlations were all positive. The litter weight at birth showed genetic antagonism with litter size born alive (-0.65) and litter size at weaning (-0.31), but positive with litter size at birth (0.47) and litter weight at weaning (0.31). The estimates of environmental correlations were larger than their corresponding genetic correlation estimates except for those between litter weight at birth and the other four traits. This study recommends simultaneous selection for two or more traits with multivariate mixed models in order to improve overall economic response.

무용전공고등학생의 자기애와 자기관리 및 섭식장애의 관계 (The Relationship among Dance-majoring High School Students Narcissism, Self-management and Eating Disorder)

  • 양소정;안병순
    • 한국콘텐츠학회논문지
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    • 제18권8호
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    • pp.408-414
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    • 2018
  • 이 연구는 섭식장애와 관련된 변인들을 탐색하고 이들과의 관계를 규명하는데 목적을 두었다. 예술고등학교에서 무용을 전공하고 있는 200명을 대상으로 설문을 통해 자료를 수집 하였으며, t-test, 일원변량분석, 중다회귀분석을 사용하여 분석한 결과 다음과 같은 결론을 도출하였다. 첫째, 성별에 따라 섭식장애는 유의한 차이가 있는 것으로 나타났으며, 학년에 따른 자기관리가 유의미한 차이가 있는 것으로 나타났다. 또한 무용경력에 따라 자기애성향, 자기관리는 유의미한 차이가 있었으며, 가정형편에 따라서는 자기애성향이 유의한 차이가 있는 것으로 나타났다. 둘째, 자기주도적 자기애 성향은 자기관리의 모든 하위요인에 정(+)의 영향을 미쳤으며 타인의존적 자기애 성향은 훈련 관리에 정(+)의 영향을 미치는 것으로 나타났다. 셋째, 타인 의존적 자기애성향은 폭식증에도 정(+)의 영향을 미치는 것으로 나타났다. 넷째, 타인의존적 자기애 성향은 대인관계를 높이고 이에 따라 폭식증을 높이는 것으로 나타나 인과관계가 있는 것으로 나타났다.

Estimation of Genetic Parameters for Somatic Cell Scores of Holsteins Using Multi-trait Lactation Models in Korea

  • Alam, M.;Cho, C.I.;Choi, T.J.;Park, B.;Choi, J.G.;Choy, Y.H.;Lee, S.S.;Cho, K.H.
    • Asian-Australasian Journal of Animal Sciences
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    • 제28권3호
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    • pp.303-310
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    • 2015
  • The study was conducted to analyze the genetic parameters of somatic cell score (SCS) of Holstein cows, which is an important indicator to udder health. Test-day records of somatic cell counts (SCC) of 305-day lactation design from first to fifth lactations were collected on Holsteins in Korea during 2000 to 2012. Records of animals within 18 to 42 months, 30 to 54 months, 42 to 66 months, 54 to 78 months, and 66 to 90 months of age at the first, second, third, fourth and fifth parities were analyzed, respectively. Somatic cell scores were calculated, and adjusted for lactation production stages by Wilmink's function. Lactation averages of SCS ($LSCS_1$ through $LSCS_5$) were derived by further adjustments of each test-day SCS for five age groups in particular lactations. Two datasets were prepared through restrictions on number of sires/herd and dams/herd, progenies/sire, and number of parities/cow to reduce data size and attain better relationships among animals. All LSCS traits were treated as individual trait and, analyzed through multiple-trait sire models and single trait animal models via VCE 6.0 software package. Herd-year was fitted as a random effect. Age at calving was regressed as a fixed covariate. The mean LSCS of five lactations were between 3.507 and 4.322 that corresponded to a SCC range between 71,000 and 125,000 cells/mL; with coefficient of variation from 28.2% to 29.9%. Heritability estimates from sire models were within the range of 0.10 to 0.16 for all LSCS. Heritability was the highest at lactation 2 from both datasets (0.14/0.16) and lowest at lactation 5 (0.11/0.10) using sire model. Heritabilities from single trait animal model analyses were slightly higher than sire models. Genetic correlations between LSCS traits were strong (0.62 to 0.99). Very strong associations (0.96 to 0.99) were present between successive records of later lactations. Phenotypic correlations were relatively weaker (<0.55). All correlations became weaker at distant lactations. The estimated breeding values (EBVs) of LSCS traits were somewhat similar over the years for a particular lactation, but increased with lactation number increment. The lowest EBV in first lactation indicated that selection for SCS (mastitis resistance) might be better with later lactation records. It is expected that results obtained from these multi-trait lactation model analyses, being the first large scale SCS data analysis in Korea, would create a good starting step for application of advanced statistical tools for future genomic studies focusing on selection for mastitis resistance in Holsteins of Korea.

경제적 스트레스와 상태.특성불안이 치주질환에 미치는 영향 (A Study on the Effects of the Economic Stress and State-Trait Anxiety on the Periodontal Disease)

  • 류혜겸
    • 치위생과학회지
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    • 제12권6호
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    • pp.583-590
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    • 2012
  • 본 연구는 경제적 스트레스와 상태 특성불안이 치주질환에 미치는 영향을 파악하여 치주질환의 예방과 발생 및 진행 정도를 미연에 방지할 수 있는 방안을 마련하기 위하여 실시되었다. 연구대상은 일부 지역 치과의원에 내원한 40~50대 성인남녀 총 326명을 대상으로 하여 구조화된 설문지와 치주상태를 측정하여 조사 분석하였다. 수집된 자료는 IBM SPSS ver. 19.0 통계프로그램(IBM Co., Armonk, NY, USA)을 이용하여 빈도와 백분율, t-test (검증), One way ANOVA (일원배치 분산분석), Multiple regression Analysis (다중회귀분석)을 실시하여 분석결과는 다음과 같다. 1. 경제적 스트레스는 치은염 지수의 고($1.12{\pm}0.72$), 중($0.85{\pm}0.62$), 저($0.88{\pm}0.62$)에 따라 통계적으로 유의한 차이를 보였다(p<0.01). 2. 상태 특성불안은 치은염 지수(p<0.001)의 고($1.16{\pm}0.71$), 중($0.81{\pm}0.63$), 저($0.86{\pm}0.60$), 치주낭 깊이(p<0.05)의 고($3.86{\pm}1.12$), 중($3.44{\pm}1.07$), 저($3.57{\pm}1.01$), 임상적 부착소실(p<0.05)의 고($3.86{\pm}1.12$), 중($3.44{\pm}1.07$), 저($3.57{\pm}1.01$)에 따라 통계적으로 유의한 차이를 보였다. 3. 치은염 지수에 영향을 미치는 요인으로 경제적 스트레스($\beta$=0.052, p<0.01)가 높을수록, 상태 특성불안($\beta$=0.052, p<0.01)이 높을수록 영향을 미치는 것으로 조사되었다. 이상의 연구결과에서 치과의료기관은 치주질환으로 힘들어 하는 환자에게 경제적 스트레스와 상태 특성불안이 치주질환에 영향을 미친다는 사실을 인식시킬 필요가 있으며 이에 따른 치주질환의 예방과 발생 및 진행 정도를 방지할 수 있는 스트레스 관리능력배양을 위한 교육프로그램 개발이 마련되어야 할 것이다.

Genome Wide Association Studies Using Multiple-lactation Breeding Value in Holsteins

  • Cho, Kwang-Hyun;Oh, Jae-Don;Kim, Hee-Bal;Park, Kyung-Do;Lee, Joon-Ho
    • Asian-Australasian Journal of Animal Sciences
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    • 제28권3호
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    • pp.328-333
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    • 2015
  • A genome wide association study was conducted using estimated breeding value (EBV) for milk production traits from 1st to 4th lactation. Significant single nucleotide polymorphism (SNP) markers were selected for each trait and the differences were compared by lactation. DNA samples were taken from 456 animals with EBV which are Holstein proven bulls whose semen is being sold or the daughters of old proven bulls whose semen is no longer being sold in Korea. High density genome wide SNP genotype was investigated and the significance of markers associated with traits was tested using the breeding value estimated by a multiple lactation model as a dependent variant. As the result of significance comparisons by lactations, several differences were found between the first lactation and subsequent lactations (from second to 4th lactation). A similar trend was noted in mean deviation and correlation of the estimated effects by lactation. Since there was a difference in the genes associated with EBV for each trait between first and subsequent lactations, a multi-lactation model in which lactation is considered as a different trait is genetically useful. Also, significant markers in all lactations and common markers for different traits were detected, which can be used as markers for quantitative trait loci exploration and marker assisted selection in milk production traits.

Mapping Quantitative Trait Loci with Various Types of Progeny from Complex Pedigrees

  • Lee, C.;Wu, X.L.
    • Asian-Australasian Journal of Animal Sciences
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    • 제14권11호
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    • pp.1505-1510
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    • 2001
  • A method for mapping quantitative trait loci (QTL) was introduced incorporating the information of mixed progeny from complex pedigrees. The method consisted of two steps based on single marker analysis. The first step was to examine the marker-trait association with a mixed model considering common environmental effect and reversed QTL-marker linkage phase. The second step was to estimate QTL effects by a weighted least square analysis. A simulation study indicated that the method incorporating mixed progeny from multiple generations improved the accuracy of QTL detection. The influence of within-genotype variance and recombination rate on QTL analysis was further examined. Detecting a QTL with a large within-genotype variance was more difficult than with a small within-genotype variance. Most of the significant marker-QTL association was detectable when the recombination rate was less than 15%.

중년여성의 분노, 지각된 스트레스 및 정신건강 상태와의 관계 (Correlational Study among Anger, Perceived Stress and Mental Health Status in Middle Aged Women)

  • 이평숙
    • 대한간호학회지
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    • 제33권6호
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    • pp.856-864
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    • 2003
  • Purpose: This study was to identify the relationships of trait anger, mode of anger expression, and perceived stress to mental health status in middle aged women. Method: The subjects were 157 middle aged women from 40s to 60s who lived in Seoul. Data was collected by questionnaire surveys using the convenience sampling. The instruments used for this study were Spielberger's trait anger scale and anger expression scale, Cohen, Kamarck, and Mermelstein's perceived stress and Derogatis's SCL-90-R. The collected data was analyzed using descriptive statistics, Pearson correlation coefficient, and Stepwise multiple regression with SAS/PC. Result: The trait anger of middle aged women indicated a significantly positive correlation to perceived stress(r=.180, p=.023) and mental health status(r.=021, p=.014). Anger-in(r=.237, p<.05), and perceived stress(p=.461, p<.01) showed significantly positive correlation to mental health status. The most significant predictor influencing health status of middle aged women was perceived stress, and anger-in and the variance explained was 27%. Conclusion: These results suggested that middle aged women with high degree of trait anger is likely to be high in stress perception. Perceived stress and anger-in are major factors influencing mental health status.

다문화가정 아동의 분노와 정신신체증상: 부모 애착의 매개효과 (Anger and Psychosomatic Symptoms in Multi-cultural Families: The Mediating Effect of Parental Attachment)

  • 문소현;안효자
    • 한국학교ㆍ지역보건교육학회지
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    • 제14권1호
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    • pp.37-47
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    • 2013
  • Objectives: A descriptive correlational study was designed to examine the relationship of anger to psychosomatic symptoms. In addition, this study investigated the mediating effect of parental attachment in relation to anger and other variable. Methods: Data were collected from 112 subjects in grade 4 or 6, and descriptive statistics, Pearson correlation coefficient, and hierachical multiple regression were used with SPSS/PC 18.0 program to analyze the data. Results: There was a significantly positive effects between state-trait anger and psychosomatic symptoms. Father attachment negatively correlated state-trait anger and psychosomatic symptoms. Also, mother attachment negatively correlated state anger and psychosomatic symptoms. However, maternal attachment was not significantly associated with trait anger. Parental attachment had a significant mediating effect in relation to state-trait anger and psychosomatic symptoms. Conclusions: For the effective management of multi-cultural children's psychosomatic symptoms, programs including parental attachment increasing strategies should be established. These programs can increase parental attachment security which is mediator role between anger and psychosomatic symptoms.

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A Genome Wide Association Study on Age at First Calving Using High Density Single Nucleotide Polymorphism Chips in Hanwoo (Bos taurus coreanae)

  • Hyeong, K.E.;Iqbal, A.;Kim, Jong-Joo
    • Asian-Australasian Journal of Animal Sciences
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    • 제27권10호
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    • pp.1406-1410
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    • 2014
  • Age at first calving is an important trait for achieving earlier reproductive performance. To detect quantitative trait loci (QTL) for reproductive traits, a genome wide association study was conducted on the 96 Hanwoo cows that were born between 2008 and 2010 from 13 sires in a local farm (Juk-Am Hanwoo farm, Suncheon, Korea) and genotyped with the Illumina 50K bovine single nucleotide polymorphism (SNP) chips. Phenotypes were regressed on additive and dominance effects for each SNP using a simple linear regression model after the effects of birth-year-month and polygenes were considered. A forward regression procedure was applied to determine the best set of SNPs for age at first calving. A total of 15 QTL were detected at the comparison-wise 0.001 level. Two QTL with strong statistical evidence were found at 128.9 Mb and 111.1 Mb on bovine chromosomes (BTA) 2 and 7, respectively, each of which accounted for 22% of the phenotypic variance. Also, five significant SNPs were detected on BTAs 10, 16, 20, 26, and 29. Multiple QTL were found on BTAs 1, 2, 7, and 14. The significant QTLs may be applied via marker assisted selection to increase rate of genetic gain for the trait, after validation tests in other Hanwoo cow populations.

노인의 신체화 증상 영향 요인 분석 (Factors Affecting Physical Symptoms of Elders)

  • 신미경;강지숙
    • 성인간호학회지
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    • 제22권2호
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    • pp.211-220
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    • 2010
  • Purpose: This study was done to identify the relationship of trait anger, health state, physical symptoms. and general characteristics to physical symptoms and to identify factors affecting physical symptoms of elderly in urban areas. Methods: The research design for this study was a descriptive survey design using a convenience sampling. Elders (n=276), who agreed to participate in this study completed a self-reporting questionnaire. The collected data were analyzed by descriptive statistics, t-test, ANOVA, Pearson's correlation coefficients, and multiple regression. Results: Study participants reported low trait anger (M=18.61), physical symptoms (M=7.15), and moderate health state (M=3.30). The 45.4%of variance in physical symptoms was significantly explained by emotional function health state (${\beta}$=-.284, p=.013), which is one of the sub-domain of the elderly health state, and trait anger (${\beta}$=3.841, p<.001). Conclusion: Findings of this study provide that the most important factors in explaining physical symptoms for the elders in Korea were emotional function health state and trait anger. Based on the findings of this study, further nursing practice and nursing research for the elders with physical symptoms should be focused on emotional support.