• Title/Summary/Keyword: Multiple-ion

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Variation of the Electrical Resistivity with ion Components of Pore Water in the Sand (사질토 간극수의 이온 성분들에 따른 전기비저항값의 변화)

  • Yu, Chan;Yoon, Chun-Gyeong;Lee, Young-Nam;Lee, Yong-Gil
    • Journal of the Korean Geotechnical Society
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    • v.15 no.1
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    • pp.185-196
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    • 1999
  • A laboratory experiment was performed to examine the relationship between resistivity and ionic components in the pore water of a sand by using soil resistivity test box and STING-Rl. The resistivity measurement was performed with the concentration changes of ionic components. Also, the resistivity change was evaluated for multiple components. The results showed that the resistivity of Arsenic was less than other heavy metals. In the case of complex components, resistivity ranges depended on the resistivity of components existed in the pore water.

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Quantitative Analysis of Pyridostigmine Bromide in Tablets by HPLC (피리도스티그민 정제의 함량 측정을 위한 HPLC 분석법)

  • Phi, Taek-San;Cho, Young;Sok, Dae-Eun;Cha, Seung-Hee;Chung, Yun-Su
    • Journal of Pharmaceutical Investigation
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    • v.21 no.3
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    • pp.171-177
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    • 1991
  • A reverse-phase, ion-pair high performance liquid chromatographic (HPLC) method for the simultaneous quantative determination of pyridostigmine and its hydrolytic product, 3-hydroxy-N-methylpyridinium (HMP), is descrihed, The assay of pyridostigmine and HMP was linear in the range of amount from 24 to 60 mg/tablet and from 2.4 to 12.0 mg/tablet, respectively, with coefficient of variation (C.V.) of 0.05-0.12% (n=7) and 0.25-0.52% (n=5), respectively, and applicable conveniently even in the case of the mixture of pyridostigmine and HMP. Meanwhile, the conventional UV method gave inaccurate results for the aged pyridostigmine tablets. In the extraction of pyridostigmine from tablets prior to be assayed by HPLC, methanol was found to be more effective than ethanol or distilled water. Multiple extraction (four times) with methanol resulted in the full recovery of pyridostigmine, whereas ethanol gave 95% recovery even after four times extraction. Based on these results. the present method would be very useful for the accurate determination of pyridostigmine in the aged pyridostigmine tablets.

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Salt Tolerance in Plants - Transgenic Approaches

  • Sangam S.;Jayasree D.;Reddy K.Janardhan;Chari P.V.B.;Sreenivasulu N.;Kishor P.B.Kavi
    • Journal of Plant Biotechnology
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    • v.7 no.1
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    • pp.1-15
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    • 2005
  • Salinity is one of the major limiting factors for agricultural productivity. In plants, accumulation of osmolytes plays a pivotal role in abiotic stress tolerance. Likewise, exclusion or compartmentation of $Na^+$ ions into vacuoles provides an efficient mechanism to avert deleterious effects of $Na^+$ in the cytosol. Both vacuolar and plasma membrane sodium transporters and $H^+-ATPases$ can provide the necessary ion homeostasis. A variety of crop plants were engineered with respect to the synthesis of osmoprotectants and ion-compartmentation, but there are other cellular pathways involved in the salinity responses that are still not completely explored. Genomics approaches are increasingly used to identify genes and pathway changes involved in salt-tolerance. The new knowledge may be used via guided genetic engineering of multiple genes to create crop plants with significantly increased productivity in saline soils. This review surveys how plants deal with high salt conditions and how salt tolerance can be improved by transgenic approaches.

Incipient Fault Detection of Reactive Ion Etching Process

  • Hong, Sang-Jeen;Park, Jae-Hyun;Han, Seung-Soo
    • Transactions on Electrical and Electronic Materials
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    • v.6 no.6
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    • pp.262-271
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    • 2005
  • In order to achieve timely and accurate fault detection of plasma etching process, neural network based time series modeling has been applied to reactive ion etching (RIE) using two different in-situ plasma-monitoring sensors called optical emission spectroscopy (OES) and residual gas analyzer (RGA). Four different subsystems of RIE (such as RF power, chamber pressure, and two gas flows) were considered as potential sources of fault, and multiple degrees of faults were tested. OES and RGA data were simultaneously collected while the etching of benzocyclobutene (BCB) in a $SF_6/O_2$ plasma was taking place. To simulate established TSNNs as incipient fault detectors, each TSNN was trained to learn the parameters at t, t+T, ... , and t+4T. This prediction scheme could effectively compensate run-time-delay (RTD) caused by data preprocessing and computation. Satisfying results are presented in this paper, and it turned out that OES is more sensitive to RF power and RGA is to chamber pressure and gas flows. Therefore, the combination of these two sensors is recommended for better fault detection, and they show a potential to the applications of not only incipient fault detection but also incipient real-time diagnosis.

SNP-Based Fetal DNA Detection in Maternal Serum Using the HID-Ion AmpliSeqTM Identity Panel

  • Cho, Sohee;Lee, Ji Hyun;Kim, Chong Jai;Kim, Moon Young;Kim, Kun Woo;Hwang, Doyeong;Lee, Soong Deok
    • The Korean Journal of Legal Medicine
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    • v.41 no.2
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    • pp.41-45
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    • 2017
  • Fetal DNA (fDNA) detection in maternal serum is a challenge due to low copy number and the smaller size of fDNA fragments compared to DNA fragments derived from the mother. Massively parallel sequencing (MPS) is a useful technique for fetal genetic analysis that is able to detect and quantify small amounts of DNA. In this study, seven clinical samples of maternal serum potentially containing fDNA were analyzed with a commercial single nucleotide polymorphism (SNP) panel, the HID-Ion $AmpliSeq^{TM}$ Identity Panel, and the results were compared to those from previous studies. Reference profiles for mothers and fetuses were not available, but multiple Y chromosomal SNPs were detected in two samples, indicating that fDNA was present in the serum and thereby validating observations of autosomal SNPs. This suggests that SNP-based MPS can be valuable for fDNA detection, thereby offering an insight into fetal genetic status. This technology could also be used to detect small amounts of DNA in mixed DNA samples for forensic applications.

Using Coffee-Derived Hard Carbon as a Cost-Effective and Eco-Friendly Anode Material for Li-Ion Batteries

  • Hong, Sung Joo;Kim, Seong Su;Nam, Seunghoon
    • Corrosion Science and Technology
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    • v.20 no.1
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    • pp.15-21
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    • 2021
  • Through a simple filtration process, followed by carbonization within a reductive environment, coffee waste grounds can be transformed into a non-porous hard carbon for use in multiple contexts. This resulting coffee-waste carbon has been evaluated as an eco-friendly and cost-effective replacement for conventional graphite. When compared with different types of carbon, our study found that the coffee-waste carbon fell into the category of hard carbon, as verified from the galvanostatic charge/discharge profiles. The coffee-waste carbon showed a superior rate capability when compared to that of graphite, while compromising smaller capacity at low C rates. During electrochemical reactions, it was also found that the coffee-waste carbon is well exposed to electrolytes, and its disordered characteristic is advantageous for ionic transport which leads to the low tortuosity of Li ions. Finally, the high irreversible capacity (low initial Coulombic efficiency) of the coffee-waste carbon, which if also often observed in amorphous carbon, can be adequately resolved through a solution-based prelithiation process, thereby proving that the coffee-waste carbon material is quite suitable for commercial use as an anode material for quickly-chargeable electrodes.

Purification of Therapeutic Serums of Snake Anti-Venom with Caprylic Acid

  • Norouznejad, Nilofar;Zolfagharian, Hossein;Babaie, Mahdi;Ghobeh, Maryam
    • Journal of Pharmacopuncture
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    • v.25 no.2
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    • pp.114-120
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    • 2022
  • Objectives: Antivenom serums have been used extensively for over a century and are the only effective treatment option for snake bites and other dangerous animal envenomations. In therapeutic serum centers, a wide range of antivenoms is made from animal serum, mainly equine and sheep, that are immunized with single or multiple venoms. This work aimed to use caprylic acid (CA) to purify therapeutic snake antivenom. Methods: Plasma was obtained from equine immunized with a mixture of venoms. Immunized plasma was obtained by precipitation of different concentrations (2-5%) of CA. This methodology was compared to that based on ammonium sulfate (AS) precipitation. Sediment plasma proteins were purified by ion-exchange chromatography. Protein assay, SDSPAGE, and agar gel diffusion were performed. Results: The total protein precipitation with AS was higher than precipitation with CA, but the best results were obtained when CA was added to the plasma until a final CA concentration of 5% was reached. Chromatography and electrophoresis indicated a stronger band for the 5% CA, and the gel diffusion assay showed antigen-antibody interaction in the purified serum. Conclusion: The use of CA compared to the routine method for purifying hyperimmune serums is a practical and cost-effective method for preparing and producing therapeutic serums. It constitutes a potentially valuable technology for alleviating the critical shortage of antivenom in Iran.

The Research and Development Trend of Cathode Materials in Lithium Ion Battery (리튬이차전지용 양극재 개발 동향)

  • Park, Hong-Kyu
    • Journal of the Korean Electrochemical Society
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    • v.11 no.3
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    • pp.197-210
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    • 2008
  • The cathode materials for lithium ion battery have been developed in accordance with the battery performance. $LiCoO_2$ initially adapted at lithium ion battery is going to be useful even at the charging voltage of 4.3 V by surface treatment or doping which drastically improved the performance of $LiCoO_2$. On the other hand, the complicate and multiple functions of recent electronic equipments required higher operational voltage and higher capacity than ever, which is going to be driving force for developing new cathode materials. Some of them are $LiNi_{1-x}{M_xO_2}$, $Li[Ni_{x}Mn_{y}Co_{z}]O_{2}$, $Li[{Ni}_{1/2}{Mn}_{1/2}]O_{2}$. Other new type of cathode materials having high safety is also developed to apply for HEV (hybrid electrical vehicle) and power tool applications. ${LiMn}_{2}{O}_{4}$ and $LiFePO_4$ are famous for highly stable material, which are expected to give contribution to make safer battery. In near future, the various materials having both capacity and safety will be developed by new technology, such as solid solution composite.

Adsorption Characteristics of Sr Ions by Coal Fly Ash-Based-Zeolite X using Response Surface Modeling Approach (반응표면분석법을 이용한 석탄회로 합성한 제올라이트 X에서의 Sr 이온 제거특성)

  • Lee, Chang-Han;Kam, Sang-Kyu;Lee, Min-Gyu
    • Journal of Environmental Science International
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    • v.26 no.6
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    • pp.719-728
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    • 2017
  • In order to investigate the adsorption characteristics for Sr ion using the Na-X zeolite synthesized from coal fly ash, batch tests and response surface analyses were carried out. The adsorption kinetic data for Sr ions, using Na-X zeolite, fitted well with the pseudo-second-order model. The uptake of Sr ions followed the Langmuir isotherm model, with a maximum adsorption capacity of 196.46 mg/g. Thermodynamic studies were conducted at different reaction temperatures, with the results indicating that Sr ion adsorption by Na-X zeolite was an endothermic (${\Delta}H^o$>0) and spontaneous (${\Delta}G^o$<0) process. Using the response surface methodology of the Box-Behnken method, initial Sr ion concentration ($X_1$), initial temperature ($X_2$), and initial pH ($X_3$) were selected as the independent variables, while the adsorption of Sr ions by Na-X zeolite was selected as the dependent variable. The experimental data fitted well with a second-order polynomial equation by multiple regression analysis. The value of the determination coefficient ($R^2=0.9937$) and the adjusted determination coefficient (adjusted $R^2=0.9823$) was close to 1, indicating high significance of the model. Statistical results showed the order of Sr removal based on experimental factors to be initial pH > initial concentration > temperature.

Energy- and Time-Dependent Branching to Competing Paths in Coupled Unimolecular Dissociations of Chlorotoluene Radical Cations

  • Seo, Jongcheol;Kim, Seung Joon;Shin, Seung Koo
    • Bulletin of the Korean Chemical Society
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    • v.35 no.3
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    • pp.833-838
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    • 2014
  • The energy- and time-dependent branching to the competing dissociation paths are studied by theory for coupled unimolecular dissociations of the o-, m-, and p-chlorotoluene radical cations to $C_7{H_7}^+$ (benzylium and tropylium). There are four different paths to $C_7{H_7}^+$, three to the benzylium ion and one to the tropylium ion, and all of them are coupled together. The branching to the multiple paths leads to the multiexponential decay of reactant with the branching ratio depending on both internal energy and time. To gain insights into the multipath branching, we study the detailed kinetics as a function of time and internal energy on the basis of ab inito/RRKM calculations. The number of reaction steps to $C_7{H_7}^+$ is counted for each path. Of the three isomers, the meta mostly goes through the coupling, whereas the para proceeds with little or no coupling. In the beginning, some reactants with high internal energy decay fast to the benzylium ion without any coupling and others rearrange to the other isomers. Later on all three isomers dissociate to the products via long-lived intermediates. Thus, the reactant shows a multiexponential decay and the branching ratio varies with time as the average internal energy decreases with time. The reciprocal of the effective lifetime is taken as the rate constant. The resulting rate-energy curves are in line with experiments. The present results suggest that the coupling between the stable isomers is thermodynamically controlled, whereas the branching to the product is kinetically controlled.