• Archives of Pharmacal Research
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• v.15 no.3
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• pp.246-250
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• 1992

Acetaminophen (AAP) and ranitidine (RT) were coadministered orally to nine rats, and the possible contribution of the gastric emptying to the plasma concentration profiles of them was examined. The drugs showed multiple plasma peaks similar to the respective ones after separated administration of each durg. IT Implies that there is no significant interaction between AAP and RT in terms of the gastric emptying or drug absorption. There were no significant linear correlations of the peak patterns (peak height and peak time) between AAP andd RT. It is contrary to the expectation from the biphasic gastric emptying (BGE) theory previously suggested for AAP and RT. The BGE theory. Therefore, seemed to have some draw-backs in explaining satisfactorily the multiple plasma peaks of AAP and RT. Two more doubts raised previously against the BGE theory were also discussed.

• Mass Spectrometry Letters
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• v.12 no.4
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• pp.137-145
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• 2021

Herein we report multiple ion mobility (IM) peaks in electrospray ionization IM mass spectrometry (ESI-IM-MS) produced by glutamine residue in peptide. The mobility features of 147 peptides were investigated using ESI-IM-MS combined with liquid chromatography. Of these peptides, 66 presented multiple IM peaks, and analysis of their sequence using collision induced dissociation (CID) revealed that glutamine (Gln), as well as proline (Pro), plays a critical role in generating multiple IM peaks. Mutant-based investigations using Gln-containing peptides indicate that the side chain of Gln promotes intermolecular interactions, inducing multiple structures of the peptide ions in the gas phase. Consequently, the present study demonstrates that the distinct ion mobility signatures identified herein can potentially be used to characterize glutamine-containing peptide ions.

• Proceedings of the Korean Vacuum Society Conference
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• 2013.02a
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• pp.654-654
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• 2013

One of the most important yet unresolved problems in molecular electronics is the controversy over the number and nature of multiple conductance peaks in single-molecule junctions. Currently, there are three competing explanations of this observation: (1) manifestation of different molecule-electrode contact geometries, (2) formation of gauche defects within the molecular core, (3) involvement of different electrode surface orientations [1]. However, the exact origin of multiple conductance peaks is not yet fully understood, which indicates our incomplete understanding of the scientifically as well as techno-logically important organic-metal contacts. To theoretically resolve this problem, we previously applied a multiscale computational approach that combines force fields molecular dynamics (FF MD), density functional theory (DFT), and matrix Green's function (MGF) calculations [2] to a thermally fluctuating haxanedithiol (C6DT) molecule stretched between flat Au(111) electrodes, but could observe only a single conductance peak [3]. In this presentation, using DFT geometry optimizations and MGF calculations, we consider molecular junctions with more realistic molecule-metal contact conformations and Au(111) electrode surface directions. We also conduct DFT-based molecular dynamics for the highly stretched junction models to confirm our conclusion. We conclude that the S-Au coordination number should be the more dominant factor than the electrode surface orientation.

• Journal of Institute of Control, Robotics and Systems
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• v.16 no.5
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• pp.415-419
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• 2010

A variety of methods for sound source localization have been developed and applied to several applications such as noise detection system, surveillance system, teleconference system, robot auditory system and so on. In the previous work, we proposed the sound source localization using the spatially mapped GCC functions based on TDOA for robot auditory system. Performance of the proposed one for the noise effect and estimation resolution was verified with the real environmental experiment under the single source assumption. However, since multi-talker case is general in human-robot interaction, multiple source localization approaches are necessary. In this paper, the proposed localization method under the single source assumption is modified to be suitable for multiple source localization. When there are two sources which are correlated, the spatially mapped GCC function for localization has three peaks at the real source locations and imaginary source location. However if two sources are uncorrelated, that has only two peaks at the real source positions. Using these characteristics, we modify the proposed localization method for the multiple source cases. Experiments with human speeches in the real environment are carried out to evaluate the performance of the proposed method for multiple source localization. In the experiments, mean value of estimation error is about $1.4^{\circ}$ and percentage of multiple source localization is about 62% on average.

• Journal of Integrative Natural Science
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• v.5 no.4
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• pp.253-256
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• 2012

The rugate porous silicons containing multiple photonic band gaps have been generated by applying a composite waveform summed three computer-generated pseudo-sinusoidal current waveforms and exhibit three sharp photonic band gaps in the optical reflectivity spectrum. Generated multiple rugate porous silicons display three rugate peaks corresponding to the each of the sine components varied from 0.42, 0.36, and 0.30 Hz, with a spacing of 0.06 Hz between each sine component. The resulting rugate PSi films have been removed from the silicon substrate by applying an lift-off current and are then made into particles by ultrasono-method in a organic solution. The sensing experiments using these particles for organic solvents such as toluene, hexane, acetone, and methanol have been achieved. Condensing of organic vapors in the pores increases the refractive indices of entire particle which results a red shift in the photonic peaks.

• Bulletin of the Korean Chemical Society
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• v.15 no.3
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• pp.181-183
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• 1994

• Journal of the Korean Institute of Telematics and Electronics B
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• v.29B no.1
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• pp.102-112
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• 1992

We have already proposed an extended fuzzy clustering algorithm which considers the importance of the data to be classified in a previous paper. In this paper, we suggest the extended fuzzy clustering algorithm based new method to slove a multiple peak detection problem, and prove experimently that this algorithm can detect the multiple peak adaptively to the noise and the shape of peaks.

• Journal of Biosystems Engineering
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• v.33 no.1
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• pp.30-37
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• 2008

Dynamic excitation and response analysis is an acceptable method to determine some of physical properties of agricultural product for quality evaluation. There is a difference in the internal viscoelasticity between sound and defective fruits due to the difference of geometric structures, thereby showing different vibration characteristics. This study was carried out to develop a portable piezoelectric film-based glove sensor system that can separate internally damaged watermelons from sound ones using an acoustic impulse response technique. Two piezoelectric sensors based on polyvinylidene fluoride (PVDF) films to measure an impact force and vibration response were separately mounted on each glove. Various signal parameters including number of peaks, energy ratio, standard deviation of peak to peak distance, zero-crossing rate, and integral value of peaks were examined to develop a regression-estimated model. When using SMLR (Stepwise Multiple Linear Regression) analysis in SAS, three parameters, i.e., zeros value, number of peaks, and standard deviation of peaks were selected as usable factors with a coefficient of determination ($r^2$) of 0.92 and a standard error of calibration (SEC) of 0.15. In the validation tests using twenty watermelon samples (sound 9, defective 11), the developed model provided good capability showing a classification accuracy of 95%.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.28 no.4C
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• pp.406-412
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• 2003

A fast multiple object motion detection method using periodogram has been proposed. Each frame is projected to vertical and horizontal directions, and then temporal FFT is applied. A line in two dimensional frequency domain indicates velocity. To estimate the velocity of an object, we intergrate along a line which passes through the origin in frequency domain. If a frame contains multiple moving objects, multiple peaks are detected corresponding to the velocity of each object. After pairing these peaks, we can determine the velocities of an object. In the proposal method we can easily pair horizontal and vertical velocity components efficiently with simple computation by combining projections in 45$^{\circ}$ and 135 $^{\circ}$ directions in addition to the vertical and horizontal direction.

• Journal of Positioning, Navigation, and Timing
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• v.4 no.3
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• pp.107-114
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• 2015

Binary Offset Carrier (BOC) signal planned for future Global Navigation Satellite System (GNSS) provided better positioning accuracy and smaller multipath error than GPS C/A signal. However, due to the multiple side peaks in the auto-correlation function (ACF) of the BOC modulated signals, a receiver may false lock onto one of the side peaks in the tracking mode. This false lock would then result in a fatal tracking error. In this paper, we propose an unambiguous tracking method for composite BOC (CBOC) signals to mitigate this problem. It aims to reduce the side peaks of the ACF of CBOC modulated signals. It is based on the combination of traditional CBOC correlation function (CF) and reference CF of unmodulated pseudo- random noise code (PRN code). First, we present that cross-correlation function (CCF) with unmodulated PRN code is close to the secondary peaks of the traditional CBOC. Then, we obtain an unambiguous correlation function by subtracting traditional CBOC ACF from these CFs. Finally, the tracking performance for the CBOC signals is examined, and it is shown that the proposed method has better performance than the traditional unambiguous tracking method in additive white Gaussian noise (AWGN) channel.