• Proceedings of the KSR Conference
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• 2011.10a
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• pp.931-938
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• 2011

Nondestructive inspection(NDI) is a testing procedure used to easily inspect an object for internal defects, abnormalities, shape, and structure, etc. without destroying it. Typical candidates for NDI include buildings, railways, aircraft, bridges, underground pipelines and various types of factory equipment. Recent advances in nondestructive evaluation(NDE) technologies have led to improved methods for quality control and in-service inspection, and the development of new options for material diagnostics. Under frame side sill in rolling stocks is designed for preventing corrosion in order to meet mechanical requirements. However during long operation time, there are corrosion in the under frame side sill caused by environmental effect, vibration and etc. This paper introduces the methods of a survey and assessment on NDI applications in Electric Multiple Units(EMU). The main objective of this paper was to obtain information on various applications and evaluation of NDI technology in EMU.

• Korean Journal of Head & Neck Oncology
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• v.9 no.1
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• pp.49-55
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• 1993

Neurofibromatosis is an autosomal deminant neurocutaneous systemic disease characterized by multiple Cafe-au-lait spots. generalized cutaneous neurofibromatosis. central nervous system tumors. skeletal defects and a myriad of somatic and endocrinologic abnormalities. It occurs in about 1:3000 live births and both sexes are equally affected. From 1989 to 1992, 21 patients who admitted to our department were evaluated in clinical aspects. Then we conclude as follows: 1) The onset was usually before 10 years of age. and the incidence between the sexes was approximately the same. 2) The familial tendency was approximately 48%. 3) The head and neck were the usual sites of the disease. 4) Bone changes occurred in about 24%. 5) Most of the tumor could be removed through early diagnosis to prevent recurrence. bone changes and malignant changes. And at the same time, trough reconstructive surgery, results both functionally as well as aesthetically satisfactory could be achieved.

• Journal of Chest Surgery
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• v.47 no.6
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• pp.536-540
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• 2014

Due to its low prevalence and because there is lack of awareness about it, Loeys-Dietz syndrome is often misdiagnosed as Marfan syndrome, which has similar skeletal abnormalities and aortic pathology. However, the differential diagnosis between these two connective tissue diseases is critical because they correspond to different surgical indications and surgical decision-making. We report two cases of successful thoracoabdominal aortic replacement in patients with previously undiagnosed Loeys-Dietz syndrome.

• Journal of the Korean Society of Fisheries and Ocean Technology
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• v.53 no.1
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• pp.67-76
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• 2017

This study carried out and analyzed survey data on captains and mates of Korean coastal large trawlers in order to examine factors affecting body abnormalities and fatigue on bridge teams from work and environment at bridges of trawlers. The summarized result may be summed up as follows: multiple regression analysis with body pain and fatigue as dependent variables yields t-values of -2.559 (p<0.05) and -3.928 (p<0.05) respectively. From the result, environment at bridges (views, spaces and exhaust) were negative factors in affecting bridge workers' pain and fatigue. Thus, it is determined to secure available spaces to improve the workers' views through windows in front of, besides and rear bridge and create more pleasant atmospheric environment at bridge.

• Journal of Veterinary Clinics
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• v.35 no.5
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• pp.211-214
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• 2018

A 14-year-old intact female Yorkshire terrier was presented with a 2-month history of shivering, intermittent pelvic limb weakness and collapse. Biochemical abnormalities revealed inappropriately increased serum insulin concentration with persistent hypoglycemia. Abdominal ultrasound revealed multiple various sized nodules in liver and fine-needle aspirates of the nodule showed typical neuroendocrine cells with high cellularity. Computed tomography (CT) revealed well-defined hyperattenuating mass in the right pancreatic lobe with homogenous enhancement. CT findings were consistent with a pancreatic tumor with malignant metastasis. Treatment was initiated with low-dose prednisolone and toceranib phosphate. The dog was maintained stable with no more progression of clinical signs and it is worth to try toceranib phosphate in a dog with metastatic insulinoma for improving the quality of life.

• Korean Journal of Veterinary Research
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• v.58 no.1
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• pp.57-60
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• 2018

An 8-year-old, castrated, male Rottweiler was referred for evaluation of chronic right thoracic limb lameness and a progressively growing mass surrounding the right elbow joint. On admission, the dog's general health was good, without abnormalities detected on physical examination. The dog was diagnosed with periarticular histiocytic sarcoma. Although draining lymph nodes and lung metastases were suspected, palliative amputation was performed. Localized histiocytic sarcomas, with destructive lesions involving multiple bones of a joint and periarticular soft-tissue masses, are uncommon in dogs. This case report presents clinical findings, imaging characteristics, and histopathologic and immunohistochemical features of a periarticular joint histiocytic sarcoma.

• Journal of Korean Medicine for Obesity Research
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• v.1 no.1
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• pp.1-11
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• 2001

Obesity is a metabolic disease associated with multiple hormonal abnormalities. Therefore, obesity management aims at balancing these endocrine malfunctions nowadays. Although many studies proved interactions of hormones related with obesity, there are still lots of controversies. Most of these malfunctions are more pronounced in central, visceral obesity than in peripheral obesity. Recently, it is revealed that a central lesion of endocrine malfunction in human visceral obesity is probably related with a hypersensitivity of hypothalamopituitary-adrenal(HPA) axis. Probably associated with this axis, Insulin and cortisol promote lipid accumulation by expressing lipoprotein lipase activity, while sex hormones and growth hormone exert the opposite effects. Also reviewed was thyroid hormone which is closely related with thermogenesis. Serotonin is prescribed as antidepressant and it is applied to some eating disorders. Recently, leptin made in fat deposit also took attentions in terms of regulator of appetite and messenger of sex signal.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2013.10a
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• pp.346-353
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• 2013

Industrial processes need to be monitored in real-time based on the input-output data observed during their operation. Abnormalities in an induction motor should be detected early in order to avoid costly breakdowns. To early identify induction motor faults, this paper effectively estimates spectral envelopes of each induction motor fault by utilizing a linear prediction coding (LPC) analysis technique and an expectation maximization (EM) algorithm. Moreover, this paper classifies induction motor faults into their corresponding categories by calculating Mahalanobis distance using the estimated spectral envelopes and finding the minimum distance. Experimental results shows that the proposed approach yields higher classification accuracies than the state-of-the-art approach for both noiseless and noisy environments for identifying the induction motor faults.

• Journal of Genetic Medicine
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• v.9 no.1
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• pp.35-37
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• 2012

Emanuel syndrome is a rare genomic syndrome which is characterized by multiple congenital anomalies and developmental disability. This syndrome is related to the presence of the supernumerary derivative chromosome originating from both chromosome 11 and 22. In most cases, one of the parents is a balanced carrier of a translocation. Our case results from 3:1 meiotic segregation of the maternal translocation carrier and is a rare case in Korea confirmed by genetic analysis.

• Biomolecules & Therapeutics
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• v.30 no.5
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• pp.399-408
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• 2022

Diabetic cardiomyopathy (DCM) is described as abnormalities of myocardial structure and function in diabetic patients without other well-established cardiovascular factors. Although multiple pathological mechanisms involving in this unique myocardial disorder, mitochondrial dysfunction may play an important role in its development of DCM. Recently, considerable progresses have suggested that mitochondrial biogenesis is a tightly controlled process initiating mitochondrial generation and maintaining mitochondrial function, appears to be associated with DCM. Nonetheless, an outlook on the mechanisms and clinical relevance of dysfunction in mitochondrial biogenesis among patients with DCM is not completely understood. In this review, hence, we will summarize the role of mitochondrial biogenesis dysfunction in the development of DCM, especially the molecular underlying mechanism concerning the signaling pathways beyond the stimulation and inhibition of mitochondrial biogenesis. Additionally, the evaluations and potential therapeutic strategies regarding mitochondrial biogenesis dysfunction in DCM is also presented.