• Imaging Science in Dentistry
• /
• v.40 no.3
• /
• pp.149-153
• /
• 2010

Brown tumor is usually diagnosed at the terminal stage of hyperparathyroidism. Diagnosis of this tumor is confirmed by endocrinologic investigations along with clinical and radiographic examination. Radiographical differential diagnosis of this tumor includes central giant cell granuloma, aneurysmal bone cyst, metastatic tumor, multiple myeloma, and Paget disease. This report presents a rare case of multiple brown tumors occurring at the maxilla and mandible, which was initially misdiagnosed as central giant cell granuloma. Plain radiographs demonstrated multiple well-defined multilocular radiolucency. CT images showed soft tissue mass with low attenuated lesions, perforation of the lingual cortical plate, and a heterogeneous mass at the right thyroid lobe. These findings were consistent with parathyroid adenoma. The patient had hypercalcemia, hypophosphatemia, and elevated alkaline phosphatase level. Surgical excision of the tumor was performed. No recurrence was observed during a 28-month follow-up.

• Journal of Power Electronics
• /
• v.19 no.5
• /
• pp.1122-1132
• /
• 2019

In this paper, aiming at high-voltage applications, transformer windings schemes of multiple-output two-transistor flyback converters are investigated, which are mainly based on the stray capacitances effect. First, based on a transformer model including equivalent stray capacitors, the operational principle of the converter is presented, and the main influence of its stay capacitors is determined. Second, the windings structures of the transformer are analyzed and designed based on the stray capacitances effect. Third, the windings arrangements of the transformer are analyzed and designed through a coupling analysis of the secondary windings and a stray capacitance analysis between the primary and secondary windings. Finally, the analysis and design conclusions are verified by experimental results obtained from a 60W laboratory prototype of a multiple-output two-transistor flyback converter.

• The Korean Journal of Cytopathology
• /
• v.11 no.2
• /
• pp.65-73
• /
• 2000

Cytologlc evaluation of cerebrospinal fluid(CSF) is an effective mean for diagnosing many disorders involving the central nervous systems(CNS). One of the most important reasons for cytologic examination of CSF is to detect metastatic or primary neoplasms of the CNS. We did a retrospective study of 1,438 CSF specimens obtained between 1992 and 1996. A total of 1,205 adult and 233 pediatric CSF specimens from 947 patients were accessed at the Department of Pathology of Seoul National University Hospital and Children's Hospital, respectively. Among 1,438 CSF cytology specimens, 169 cases(11.8%, 77 patients) including 135 adult cases(59 patients) and 34 pediatric cases(18 patients) were positive for malignant cells. Diagnoses included 50 metastatic carcinomas(adult, 60; pediatric, 0); 46 malignant lymphomas(adult, 44; pediatric, 2); 21 leukemias(adult, 20; pediatric, 1); 4 retinoblastomas(adult, 0; pediatric 4); 2 rhabdomyosarcomas(adult, 0; pediatric, 2); 1 multiple myeloma(adult, 1; pediatric, 0), and 35 primary CNS neoplasms(adult, 10; pediatric, 25). The most commonly identified metastatic carcinomas in adults were adenocarcinoma. Their primary sites were the lung, gastrointestinal tract, and breast in order of frequency. The most common primary CNS neoplasm in children was medulloblastoma.

• The Journal of Korean Institute of Communications and Information Sciences
• /
• v.36 no.11A
• /
• pp.892-902
• /
• 2011

The opportunistic spatial orthogonalization (OSO) scheme, proposed by Cong Shen and Michael P. Fitz, allows the existence of secondary users during the period in which the primary user is occupying all licensed bands. This paper introduces an active secondary user selection algorithm which mitigates the interference from the primary user transmitter to the secondary user receiver based on single-input multi-output system without altering a primary user's transmission strategy. A proposed algorithm guarantees the minimum average throughput of the primary user and overcomes the average sum throughput of a conventional OSO. We have numerically analyzed the average throughput under various constraints.

• Journal of Yeungnam Medical Science
• /
• v.39 no.3
• /
• pp.256-261
• /
• 2022

Sarcoidosis often involves the liver. However, primary hepatic sarcoidosis confined to the liver without evidence of systemic involvement is rare. We report the case of a 37-year-old man with hepatic sarcoidosis who initially presented with elevated liver enzymes and suspicious cirrhotic nodules on computed tomography. The patient had cirrhosis but did not have portal hypertension. Based on the initial histopathologic finding of chronic granulomatous inflammation and the common clinical characteristics of sarcoidosis, he was initially diagnosed with primary biliary cholangitis, and his daily dosage of ursodeoxycholic acid was increased to 900 mg. After 14 months of treatment, his total serum bilirubin concentration was 10.9 mg/dL (upper normal limit, 1.2 mg/dL). Additionally, a transjugular liver biopsy revealed multiple noncaseating granulomas. He was diagnosed with primary hepatic sarcoidosis involving the lungs, heart, spleen, kidneys, and skin. Treatment with methylprednisolone was initiated. Two weeks later, he was started on azathioprine, and the dose of steroid was simultaneously reduced. These findings indicate the importance of including hepatic sarcoidosis as a possible diagnosis in patients with elevated liver enzymes or cryptogenic cirrhosis.

• Clinics in Shoulder and Elbow
• /
• v.25 no.1
• /
• pp.42-48
• /
• 2022

Background: Total shoulder arthroplasty (TSA) has been demonstrated to be an effective treatment for multiple shoulder pathologies. The purpose of our study was to compare the relative value units (RVUs) per minute of surgical time for primary and revision TSA. Methods: The American College of Surgeons National Surgical Quality Improvement Program database was queried to identify patients that underwent primary TSA, one-component revision TSA, and two-component revision TSA between January 1, 2015 and December 31, 2017 using current procedure terminology codes. RVUs were divided by mean operative time for each procedure to determine the amount of revenue generated per minute. Rates were compared between the groups using a one-way analysis of variance with post-hoc Tukey test. Statistical significance was set at p<0.05. Results: When dividing compensation by surgical time, we found that two-component revision generated more compensation per minute compared to primary TSA (0.284±0.114 vs. 0.239±0.278 RVU per minute or $10.25±$4.11 vs. $8.64±$10.05 per minute, respectively; p=0.001). Conclusions: The relative value of revision TSA procedures is weighted to account for the increased technical challenges and time associated with these procedures. This study confirms that reimbursement is higher for revision TSA compared to primary TSA.

• Journal of Environmental Health Sciences
• /
• v.30 no.3
• /
• pp.191-206
• /
• 2004

The present study investigated the hypothesis that a extremely low frequency magnetic field partially suppresses the synthesis of melatonin in a group of 28 primary schoolchildren living nearby and 60 primary schoolchildren aged 12 years living far away from overhead transmission power lines from December 2003 to April 2004 in Seoul, Korea. The mean personal exposure levels of the primary schoolchildren living nearby overhead transmission power line were 0.37 ${\mu}$T, whereas the value for the primary schoolchildren living away from overhead transmission power line 0.05 mT. From simple analyses, the mean melatonin levels in the primary schoolchildren living nearby were lower than away from overhead transmission power line, but not statistically significant differences in the levels of the melatonin (p=0.2421), whereas the statistically significant differences in the levels of the melatonin related to the distance from residence to power line less and more than 100 m by cut-off point (p=0.0139). In multiple linear regression analyses, distance from residence to power line (p=0.0146) and dietary habit about burned meat (p=0.0170) proved to be significant risk factors in the mean nocturnal melatonin levels in the primary schoolchildren. In conclusion, these results demonstrate that urinary levels of nocturnal melatonin are not altered in primary schoolchildren exposed to extremely low frequency magnetic field(ELF-MF) at overhead transmission power line.

• Biomolecules & Therapeutics
• /
• v.23 no.4
• /
• pp.327-332
• /
• 2015

Primary cilia have critical roles in coordinating multiple cellular signaling pathways. Dysregulation of primary cilia is implicated in various ciliopathies. To identify specific regulators of autophagy, we screened chemical libraries and identified mefloquine, an anti-malaria medicine, as a potent regulator of primary cilia in human retinal pigmented epithelial (RPE) cells. Not only ciliated cells but also primary cilium length was increased in mefloquine-treated RPE cells. Treatment with mefloquine strongly induced the elongation of primary cilia by blocking disassembly of primary cilium. In addition, we found that autophagy was increased in mefloquine-treated cells by enhancing autophagic flux. Both chemical and genetic inhibition of autophagy suppressed ciliogenesis in mefloquine-treated RPE cells. Taken together, these results suggest that autophagy induced by mefloquine positively regulates the elongation of primary cilia in RPE cells.

• Journal of The Korean Astronomical Society
• /
• v.35 no.1
• /
• pp.35-40
• /
• 2002

Gaudi, Naber & Sackett pointed out that if an event is caused by a lens system containing more than two planets, all planets will affect the central region of the magnification pattern, and thus the existence of the multiple planets can be inferred by detecting additionally deformed anomalies from intensive monitoring of high magnification microlensing events. Unfortunately, this method has important limitations in identifying the existence of multiple planets and determining their parameters (the mass ratio and the instantaneous projected separation) due to the degeneracy of the resulting light curve anomalies from those induced by a single planet and the complexity of multiple planet lensing models. In this paper, we propose a new channel to search for multiple planets via microlensing. The method is based on the fact that the lensing light curve anomalies induced by multiple planets are well approximated by the superposition of those of the single planet systems where the individual planet-primary pairs act as independent lens systems. Then, if the source trajectory passes both of the outer deviation regions induced by the individual planets, one can unambiguously identify the existence of the multiple planets. We illustrate that the probability of successively detecting light curve anomalies induced by two Jovian-mass planets located in the lensing zone through this channel will be substantial. Since the individual anomalies can be well described by much simpler single planet lensing models, the proposed method has an important advantage of allowing one to accurately determine the parameters of the individual planets.

• Journal of Korean society of Dental Hygiene
• /
• v.4 no.2
• /
• pp.165-177
• /
• 2004

The purpose of this study was to analyze the influence of child's general property, mother's social and economic property, mother's knowledge and behavior in oral hygiene upon the appearance and treatment of child's primary tooth decay. For the purpose, oral examination was applied to one hundred three(103) small children who were at the age between four(4) and seven(7) and went to two(2) places of day care centers located in Seoul, and questionnaire was done to their mothers. The results of the study are as follows. 1. The number of children's dt is 1.55, the number of their ft is 1.42, dft index for primary tooth is 2,98, ft rate is 45.61%, and the higher child's age is, the higher their value is. 2. Mother's age, educational background, and occupation does not show significant difference with dft index for primary tooth. The higher mother's monthly average income is, the higher child's ft rate is. 3. dft index for primary tooth does not show significant difference according 10 mother's knowledge in oral hygiene. And, the child of mother using dental floss does show higher it rate in comparison with the one of mother who does not use dental floss, 4. Experience using dental clinic to treatment tooth decay does show significant difference with dft index for primary tooth. And experience using dental clinic for the purpose of oral examination and preventive treatment does show significant difference with ft rate. 5. From the result of multiple regression with dependent variable of dft index for primary tooth, there is no variable having significant influence. From the result of multiple regression with dependent variable of ft rate, explanatory variable is 43%, child's age, mother's occupation, mother's monthly average income, and experience using dental clinic to prevent tooth decay are significant explanatory elements. Through the above results, we can know that mother should practice positive behavior in oral hygiene for child to improve oral health. Under the reason, oral health education should be applied toward mothers as soon as possible, and governmental support should be followed so that mothers can participate in the education.