• The Journal of the Korea Contents Association
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• v.16 no.1
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• pp.655-665
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• 2016

This study analyzed how work environment of staff in group homes on their job satisfaction targeting 148 persons. As a result, this study found that the staff recognize challenge and role ambiguity at the level which is above level ranging from 3.08 to 3.61 points with respect to 6 subdomains of work environment, but showed a relative vulnerability regarding comfortability, monetary reward, role conflict and workload as below average ranging from 1.80 to 2.73 points. Results of multiple regression analysis show that challenge and role ambiguity exert a significant influence on their job satisfaction. The above results suggest that it is necessary to provide staff with an opportunity for self-development and challenge by specifying service standards for social rehabilitation teachers in work environment and strengthening group home support system in various ways, enhancing support or advocacy necessary for solving problems.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.2
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• pp.1017-1021
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• 2013

The cellular apoptosis susceptibility (CSE1L) gene has been demonstrated to regulate multiple cellular mechanisms including the mitotic spindle check point as well as proliferation and apoptosis. However, the importance of CSE1L in human colon cancer is largely unknown. In the present study, we examined expression levels of CSE1L mRNA by semiquantitative RT-PCR. A lentivirus-mediated small interfering RNA (siRNA) was used to knock down CSE1L expression in the human colon cancer cell line RKO. Changes in CSE1L target gene expression were determined by RT-PCR. Cell proliferation was examined by a high content screening assay. In vitro tumorigenesis was measured by colony-formation assay. Cell cycle distribution and apoptosis were detected by flow cytometric analysis. We found CSE1L mRNA to be expressed in human colon cancer cells. Using a lentivirus based RNAi approach, CSE1L expression was significantly inhibited in RKO cells, causing cell cycle arrest in the G2/M and S phases and a delay in cell proliferation, as well as induction of apoptosis and an inhibition of colony growth capacity. Collectively, the results suggest that silencing of CSE1L may be a potential therapeutic approach for colon cancer.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• v.37 no.1
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• pp.54-61
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• 2011

Introduction: Bisphosphonates is used widely for the treatment of the Paget's disease, multiple myeloma, bone metastases of malignant tumors with the prevention of pain and their pathological fracture. However, it was recently suggested that bisphosphonates related osteonecrosis of the jaw (BRONJ) is a side effect of bisphosphonate use. Materials and Methods: Twenty-four individuals, who were referred to the Department of Oral and Maxillofacial surgery, Dankook University Dental Hospital, were selected from those who had exposed bone associated with bisphosphonates from January, 2005 to December, 2009 according to the criteria of American Association of Oral and Maxillofacial Surgeons (AAOMS) for BRONJ. The patients group consisted of 7 males and 17 females between the age of 46 to 78 years (average 61.8 years). Each patient had panoramic imaging, computed tomography (CT), whole body bone scanning performed for a diagnosis and biopsy sampling from the necrotizing tissue. C-terminal cross-linking telopeptide of type I collagen (CTX) level of patients who had undergone surgical intervention was measured 7 days before surgery. Results: The main cause of bone exposure was post-extraction (15), chronic periodontitis (4), persistent irritation of the denture (3). Twenty people had undergone BRONJ treatment for two to eight months except for 4 people who had to maintain the bisphosphonates treatment to prevent a metastasis and bone trabecular pain with medical treatment. When the bisphosphonate treatment was suspended at least for 3 months and followed up according to the AAOMS protocols, the exposed necrotizing bones were found to be covered by soft tissue. Conclusion: Prevention therapy, interruption of bisphophonates for at least 3 months and cooperation with the physician for conservative treatment are the essential for treating BRONJ patient with high risk factors. The CTX level of BRONJ patients should be checked before undergoing surgical intervention. Surgical treatments should be delayed in the case of a CTX level <150 pg/mL.

• Journal of Korean society of Dental Hygiene
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• v.11 no.5
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• pp.791-799
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• 2011

Objectives : This study aimed at examining the aspects of utilization of the dental services in some regions and analyzing the related factors with a view to helping the old solve the dental problems and overcome the difficulties. Methods : This investigation was intended for 422 old people living in Jeon-ju city and Jang-su county from July 18, 2006 to August 25 by direct interviewing posing questions. The survey data sets were analyzed by chi-square, correlation, multiple regression and logistic regression. Results : 1. The average number of the existing teeth per an old person was 13.6 and the 28.8% of the old who didn't use denture called for dentures. 2. The annual coefficient of utilization in dental services for an old person was 52.3% and the annual average visits to dental clinics were 3.12 days while 38.6% of the old experienced illegal dental treatments. 3. The affecting factors on the dental utilization for treatment were as follows: family income, dental clinics available, the number of existing teeth, the days of dental trouble, the recognition of the prevention of the dental disease, the knowledge for the dental treatment and the oral health judged by himself. 4. The major variables influencing the utilization of dental services were spouse presence, form of family, income, having a regular dental care, denture presence and the experience of inconvenience in living. Conclusions : To conclude, the following suggestions could be made. First, It was necessary that enforcement practice of free dental prosthesis service and application to the national health insurance in old people's prosthetic therapy for government support because the economic factor was barrier to utilization of the dental services. Second, Dental clinic was required to the health center because availability of common dental services was big impact in utilization of the dental services.

• Journal of Society of Preventive Korean Medicine
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• v.21 no.2
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• pp.35-44
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• 2017

Objectives : The purpose of this study was to investigate the association between quality of life and Mibyeong index of abnormal symptoms by the Mibyeong state. Methods : A total of 1,100 people were recruited into this study and were collected by specialized research company. The data were collected by personal information using MBI(Mibyeong Index) and SF-12 (Short form-12) and were analyzed with SPSS (version 21.0) computer program, and included Pearson's chi-square test, ANOVA, Pearson's correlation coefficient, and multiple regression analysis. Results : The Mibyeong Index which represents abnormal symptom type showed significant difference for Mibyeong state (p<.001). In Total subject, fatigue, pain, low sleep quality and indigestion were found to be significant predictors of PCS(Physical Component Summary). In Healthy group, pain was found to be significant predictor of PCS. In MI 1 group, fatigue, pain, indigestion and anxiety were found to be significant predictors of PCS. In MI 2 group, fatigue, pain and low sleep quality were found to be significant predictors of PCS. In Total subject, fatigue, depression, anger and anxiety were found to be significant predictors of MCS (Mental Component Summary). In Healthy group, indigestion and anxiety were found to be significant predictors of MCS. In MI 1 group, depression and anger were found to be significant predictors of MCS. In MI 2 group, fatigue and depression were found to be significant predictors of MCS. Conclusions : The relationship between Quality of life and MBI changes according to Mibyeong state. We expect that this result could be contribute to health management of people in Mibyeong state.

• Journal of Korean society of Dental Hygiene
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• v.10 no.6
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• pp.983-990
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• 2010

Objectives : This study was to investigate the level of oral health, xerostomia, and oral health related activities of daily living(ADL) and the clinical factors influencing oral health related quality of life(OHIP-14) in elderly for visiting healthcare. Methods : Data were obtained from a cross-sectional survey of 106 elderly people(mean age=$77.5{\pm}4.98$). Participants in the study were recruited when they attended the public health center in Cheonan-si. Data were collected by means of a personal interview from July 19 through to August 20, 2010. Oral health related ADL, OHIP-14 and dry mouth was measured by the total 24-items. The data was analysed with t-test, one-way ANOVA, and multiple regression using the SPSS program. Results : Participants had a mean of 13.6 remaining natural teeth, which was significantly with age and perceived oral health. Xerostomia score achieved a mean of 6.39 out of a maximum 12 points. Powerful predictors of OHIP-14 were natural teeth, masticatory difficulty, oral pain, PHP index, perceived oral health, age and living together for the elderly Conclusions : Based on the findings, OHIP-14 has a significantly impact on oral health related ADL. These results suggest that elder people oral health promotion should be developed assessment index which was measured predictors related oral health in the elderly for visiting healthcare.

• The Journal of the Korea Contents Association
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• v.12 no.9
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• pp.234-243
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• 2012

The purpose of this study was to estimate the prevalence of musculoskeletal symptoms and work-related factors of these symptoms in dental hygienists. The self-administered questionnaire was surveyed and collected from August 1-12 of 2011 targeting 210 dental hygienists Seoul, Gyeonggi, Daegu, Pohang. Except 5 people whose responses are not clear and who suffered accident, the analysis was made on 205 people. Data analysis was performed using the chi square test and multiple logistic regression analysis using the SPSS WIN(ver 18.0) program, RULA and, REBA. The overall Experience rate of musculoskeletal symptoms was 95.6% (196/205). The specific Experience rate of musculoskeletal symptoms for different regions of the body were as follows:The highest was shown 82.4% in Neck-shoulders(R), 78% in Neck, 69.8% in shoulders(R), 66.3%in Wrist(R). Therefore, Improvements of working environments in dental clinics are needed to prevent musculoskeletal disease development in dental hygienists.

• Korean Journal of Human Ecology
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• v.19 no.6
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• pp.1031-1044
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• 2010

Corresponding to the rapid growth of the aging population without an adequate social safety net for the elderly, older people face great disadvantages due to sudden illness or poor health and a lack of support from the younger generation. Furthermore, older women are suffering from a drastic deterioration of their economic status because of insufficient retirement savings. Examining the impact of labor force participation and living arrangement on health status and life satisfaction in later life, it is important to consider gender differences in context of social policies for the elderly. Using data based on a stratified national sample of the elderly by the Korean Longitudinal Study of Aging (KLoSA), multiple regression model were used to estimate the relationships between labor force participation and health status and subjective life satisfaction concerning the quality of their later life. The result indicates that good health status and high level of life satisfaction are associated with the type of paid work status for the elderly men, but those are associated with the type of non paid work, such as family businesses employees for the elderly women. Significant differences in chronic health condition and subjective life satisfaction by employment characteristics are found among the elderly. In addition, older women's high level of life satisfaction was associated with the participation of the social activity. The major conclusion from these results should help us understand gender differences in the elderly and acknowledge further exploration of gender variations in these people's later life.

• Korean Journal of Applied Biomechanics
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• v.19 no.2
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• pp.387-397
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• 2009

Physical activity has been increased with increased leasure time. Specifically, due to our mountainous geographical benefits, people actively participate in hiking and climbing as regular daily activities. Thus, more stable and comfortable hiking boots are required to walk on uneven and sloped rocky surface for a long period of time. 5 male subjects were recruited for testing planter pressure patterns of four different conditions(barefoot, classic hiking boot, stiffness 60 and stiffness 65). Tested hiking boots(stiffness 60 and stiffness 65) consists of the multiple pieces of outsoles as they are designed for a better shock absorption. In the results, some positive aspects of stiffness 60 and stiffness 65 such as wide contact area and powerful propulsive patterns at take off was observed compared to the classic hiking boots. Therefore, biomechanical development of hiking related clothes and footwear as well as equipment would be beneficial for people who enjoy hiking to maximize their quality of activities.

• The Journal of the Korea Contents Association
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• v.18 no.1
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• pp.222-231
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• 2018

This study aims to examine the effect of food therapy on multi-dimensional health and to suggest valuable information for diet of today's people. The participants were adults over 30 years old, living in Seoul and Gyeonggi district. To examine the effect of food therapy, the study sampled 220 questionnaire out of 230. The multi-dimensional health was measured by Huangdi Neijing's principle on food therapy. And the food therapy was measured by participants' experience, the dosage and the period of the dosage. The data has analyzed by independent sample t-test and multiple regression analysis. The results are as follows: First, the dosage and the period dosage showed significant effect on medical health. Second, no variable showed significant effect on functional health. Third, no variable showed significant effect on subjective health. Therefore, the food therapy showed significant effect on participants' medical health. The result shows that the food therapy has significant effect on people's health.