• Title/Summary/Keyword: Multiple Impacts

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Polysaccharides Obtained from Vegetables: an effective source of alternative excipient

  • Ananta Choudhury;Satyabrat Sarma;Snehashis Sarkar;Madhusmita Kumari;Biplab Kumar Dey
    • Journal of Pharmacopuncture
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    • v.25 no.4
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    • pp.317-325
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    • 2022
  • Polymers are the major constructive material of pharmaceutical formulations that play a prime role in designing effective drug-delivery systems and releasing drugs at their sites of application. Polymers are composed of multiple repeating units of high molecular mass components with attendant properties. Most synthetic polymers are non-biocompatible, expensive, and extremely inclined to deliver adverse impacts. Meanwhile, edible polymers obtained from natural sources have gained remarkable recognition for their promising use in modern medicine. Moreover, polymers derived from natural sources are generally preferred due to certain of their unique features such as abundant availability, biocompatibility, nontoxicity, economical, safe, and effective functions that fit the purpose. Polysaccharides including starch, cellulose, hemicellulose, pectin, and mucilage are identified as a major class of naturally obtained molecules that have a substantial role as functional polymers. This review summarizes the potential role of polysaccharides derived from vegetable sources such as adhesives, anticaking agents, binders, disintegrants, emulsifiers, film-framing agents, and thickeners. This is simply an opportunity to abandon synthetic excipients that hurt our bodies and think back to nature from where we originate.

Effect of Abiotic Factors on Fumosorinone Production from Cordyceps fumosorosea via Solid-State Fermentation

  • Tahir Khan;Dong-Hai Hou;Jin-Na Zhou;Yin-Long Yang;Hong Yu
    • Mycobiology
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    • v.51 no.3
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    • pp.157-163
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    • 2023
  • Cordyceps fumosorosea is an important species in the genus of Cordyceps, containing a variety of bioactive compounds, including fumosorinone (FU). This study was a ground-breaking assessment of FU levels in liquid and solid cultures. The present study focused on the impacts of solid-state fermentation (SSF) using solid substrates (wheat, oat, and rice), as well as the effects of fermentation parameters (pH, temperature, and incubation period), on the generation of FU. All the fermentation parameters had significant effects on the synthesis of FU. In a study of 25 ℃, 5.5 pH, and 21 days of incubation period combinations calculated -to give maximal FU production, it was found that the optimal values were 25 ℃, 5.5 pH, and 21 days, respectively. In a solid substrate medium culture, FU could be produced from SSF. At 30 days, a medium composed of rice yielded the most FU (798.50 mg/L), followed by a medium composed of wheat and oats (640.50 and 450.50 mg/L), respectively. An efficient method for increasing FU production on a large scale could be found in this approach. The results of this study might have multiple applications in different industrial fermentation processes.

The One-to-one Comparison of the Pre-reversal Enhancement Characteristics with the Equatorial Plasma Bubble Occurrence using Multiple Satellite Data

  • Oh, S.J.;Kil, H.;Kim, Y.H.
    • Bulletin of the Korean Space Science Society
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    • 2009.10a
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    • pp.38.3-39
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    • 2009
  • Equatorial Plasma Bubble (herafter, EPB) is a common feature in low-latitude F-region during the night time. Since EPB causes significant impacts on the satellite communication and navigation systems, its accurate forecast is highly demanded by the GNSS users. Thus, further understanding of these features and their configuration is a challenging issue in space weather studies. The day-to-day variability of the plasma bubble activity was investigated by analyzing the TIMED/GUVI, ROCSAT-1, DMSP, and CHAMP satellite data. The pre-reversal enhancement (PRE) is known as the most important single parameter for the onset of plasma bubbles but we do not know yet to what extent the day-to-day variability of the bubble activity can be attributed to the PRE. We obtained the magnitude of the PRE from ROCSAT-1 and the occurrence of bubbles in relation to the PRE was investigated by using the coincident observations of EPBs from TIMED/GUVI, DMSP, and CHAMP. By conducting one-to-one comparison of the PRE characteristics with the EPB occurrence we examined the role of the PRE in the onset of EPBs.

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Hazard Recognition and Construction Safety Training Efficacy using Interactive Virtual Reality (VR)

  • Saiyad, Meeranali;Rybkowski, Zofia K.;Suermann, Patrick;Dixit, Manish;Luhan, Gregory;Shanbari, Hamzah
    • International conference on construction engineering and project management
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    • 2022.06a
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    • pp.1209-1216
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    • 2022
  • The majority of construction site incidents occur due to a lack of hazard awareness among workers on job sites. This lack of awareness is despite mandatory construction safety training, typically in the form of written content (safety manuals) or of images depicting hazards. To reduce job-site injuries and fatalities, general contractors have started adopting Virtual Reality (VR) to impart safety training to job site personnel. VR safety training can take the form of an immersive simulation comprising potential safety hazards intentionally embedded into a virtual job site; users are required to identify these hazards within a specified time frame with the expectation that they will be more adept at recognizing hazards on an actual job-site, resulting in fewer accidents. This research study seeks to identify the actual impacts of VR on construction safety awareness among participants. The research addresses the following question: Does VR improve hazard recognition awareness? The primary objective is to evaluate participants' performance of past construction safety awareness against present construction safety awareness after receiving VR training. Participants were asked to complete a multiple-choice Qualtrics™ questionnaire. The results of the study showed a statistically significant knowledge gain advantage with respect to hazard recognition and construction safety awareness with the use of interactive, immersive VR over a more conventional and passive safety training method.

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Multiple characteristic response damage analysis of large-span space structures based on equivalent damping ratio

  • Wei, Jun;Yang, Qingshun;Zhou, Lexiang;Chen, Fei
    • Earthquakes and Structures
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    • v.23 no.4
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    • pp.339-352
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    • 2022
  • Due to the large volume and generally as a public building, the damage of large-span space structures under various non-conventional loads will cause greater economic losses, casualties, and social impacts, etc. Therefore, it is particularly important to evaluate the seismic performance of large-span space structures. This paper taked a multipurpose sports center as an example and considered its synergistic deformation based on the method of equivalent damping ratio. Furthermore, The ABAQUS software was used to analyze the time-history and energy response of the multipurpose sports center under the action of rare earthquakes, and proposed a quantitative damage index to assess the overall damage of the structure. Finally, the research results indicated that the maximum inter-story drift ratio of the multipurpose sports center under the action of rare earthquakes was less than its limit value. The frame beams presented different degrees of damage, but the key members were basically in an elastic state. The bearing capacity did not reach the limit value, which satisfied the intended seismic performance target. This study taked an actual case as an example and proposed a relevant damage evaluation system, which provided some reference for the analysis of the seismic performance of large-span space structures.

Nurses' Colleague Solidarity and Job Performance: Mediating Effect of Positive Emotion and Turnover Intention

  • Jizhe Wang;Shao Liu;Xiaoyan Qu;Xingrong He;Laixiang Zhang;Kun Guo;Xiuli Zhu
    • Safety and Health at Work
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    • v.14 no.3
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    • pp.309-316
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    • 2023
  • Background: Job performance is known as an essential reflection of nursing quality. Colleague solidarity, positive emotion, and turnover intention play effective roles in a clinical working environment, but their impacts on job performance are unclear. Investigating the association between nurses' colleague solidarity and job performance may be valuable, both directly and through the mediating roles of positive emotion and turnover intention. Methods: In this cross-sectional study, a total of 324 Chinese nurses were recruited by convenience sampling method from July 2016 to January 2017. Descriptive analysis, Spearman's correlation analysis, and the structural equation model were applied for analysis by SPSS 26.0 and AMOS 24.0. Results: A total of 49.69% of participants were under 30 years old, and 90.12% of participants were female. Colleague solidarity and positive emotion were positively connected with job performance. The results indicated the mediating effects of positive emotion and turnover intention in this relationship, respectively, as well as the chain mediating effect of positive emotion and turnover intention. Conclusions: In conclusion, dynamic and multiple supportive strategies are needed for nurse managers to ameliorate nursing job performance by improving colleague solidarity and positive emotion and decreasing turnover intention based on the job demand-resource model.

Investigating the role of nano in preserving the environment with new energy and preventing oil pollution

  • Yong Huang;Lei Zhang
    • Advances in nano research
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    • v.15 no.6
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    • pp.541-550
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    • 2023
  • The escalating growth of industrial sectors has led to a pervasive global problem—oil pollution, particularly in industrial areas. The release of substantial volumes of oil and its by-products into the environment has resulted in extensive contamination. Multiple factors contribute to the entry of these substances into water bodies and soils, thereby inflicting irreparable consequences on ecosystems, natural resources, and human health. Consequently, it becomes imperative to comprehend the characteristics and behavior of oil pollution, anticipate its impacts, and develop effective mitigation strategies. Understanding this intricate issue requires considering the physicochemical properties of the environment, the interactions between oil and sediments, and biological factors such as evaporation and dissolution. Although the oil industry has brought about remarkable advancements, its activities have raised significant concerns regarding pollution from extraction and production processes. Oil-rich nations face a particularly challenging predicament of soil pollution caused by petroleum compounds. The areas surrounding oil exploration mines and refineries often endure contamination due to oil leakages from storage tanks and transmission lines resulting from deterioration and damage. Investigating the dispersion of such pollutants and devising methods to remediate petroleum-contaminated soil represent crucial and intricate issues within the realm of environmental geotechnics.

The Effects of Entrepreneurial Experience, Business Model Innovation and Financing on the Performance of New Ventures (벤처기업 창업자의 창업경험, 비즈니스 모델 혁신 및 자금조달이 초기 성과에 미치는 영향)

  • Jongseon Lee;Sangmoon Park
    • Asia-Pacific Journal of Business
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    • v.15 no.1
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    • pp.179-192
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    • 2024
  • Purpose - The purpose of this study is to examine the effect of entrepreneurial experience, business model innovation and financing on new venture performance. Design/methodology/approach - This study analyzes survey data on new ventures in Korea and investigated research hypothesis by multiple regression analysis. Findings - Founders' prior startup experience have different impacts on performance depending on whether they had a successful or failed startup. Successful experience has a positive impact on early performance, while failure experience has a negative impact. Business model innovation shows a positive and significant relationship with early performance. External financing has different effects depending on the type of funding source and performance variables. VC funding is positively related to employment creation, while government R&D funding is negatively related to sales volume. Research implications or Originality - This study confirms that the impact of entrepreneurial experience on early performance varies depending on the characteristics of successful and unsuccessful entrepreneurs. It also empirically confirms that business model innovation has a significant impact on early performance. We empirically examine the relationship between various external financing sources of venture firms and early performance. Since the effects of entrepreneurial experience, business model innovation, and external financing on early stage performance may be different, entrepreneurs should consider these relationships when pursuing early stage business opportunities.

The Determinants and their Time-Varying Spillovers on Liquefied Natural Gas Import Prices in China Based on TVP-FAVAR Model

  • Ying Huang;Yusheng Jiao
    • Journal of Information Processing Systems
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    • v.20 no.1
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    • pp.93-104
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    • 2024
  • China is playing more predominant role in the liquefied natural gas (LNG) market worldwide and LNG import price is subject to various factors both at home and abroad. Nevertheless, previous studies rarely heed a multiple of factors. A time-varying parameter factor augmented vector auto-regression (TVP-FAVAR) model is adopted to discover the determinants of China's LNG import price and their dynamic impacts from January 2012 to December 2021. According to the findings, market fundamentals have a greater impact on the import price of natural gas in China than overall economic demand, financial considerations, and world oil prices. The primary determinants include domestic gas consumption, consumer confidence and other demand-side information. Then, there are diverse and time-varying spillover effects of the four common determinants on the volatility of China's LNG import price at different intervals and time nodes. The price volatility is more sensitive and long-lasting to domestic natural gas pricing reform than other negative shocks such as the Sino-US trade war and the COVID-19 pandemic. The results in this study further proves the importance of domestic natural gas market liberalization. China ought to do more to support the further marketization of natural gas prices while working harder to guarantee natural gas supplies.

Impacts of death perceptions, terminal care stress, and life satisfaction on attitudes toward end-of-life care among nurses at a tertiary hospital (죽음인식, 임종간호 스트레스, 삶의 만족도가 상급종합병원 간호사의 임종간호태도에 미치는 영향)

  • Yoon Young Shin;Haejung Lee
    • Journal of Korean Biological Nursing Science
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    • v.26 no.3
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    • pp.218-227
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    • 2024
  • Purpose: This study investigated the factors influencing attitudes toward end-of-life care among nurses at a tertiary hospital in Korea. Specifically, it examined the roles of nurses' characteristics, death perceptions, terminal care stress, and life satisfaction. Methods: The participants included 150 nurses working at a tertiary hospital, who were recruited between August 15 and September 19, 2023. Data were collected through an online survey and analyzed using descriptive statistics, the t-test, analysis of variance, Pearson correlation coefficients, and multiple regression analysis with SPSS/WIN 28.0. Results: Nurses' attitudes toward end-of-life care were positively correlated with death perceptions (β = .28, p < .001), 3 years or more of clinical experience (β = .25, p = .001), the experience of an acquaintance death (β = .22, p = .002) and life satisfaction (β = .20, p = .004). These variables explained 34.0% of the total variance in attitudes toward end-of-life care. Conclusion: It is essential to develop and implement individualized end-of-life nursing education programs, particularly utilizing simulations, for nurses with limited clinical experience and low levels of death perceptions. Further research should explore attitudes toward end-of-life care among various healthcare providers with a broader regional scope to improve the overall quality of end-of-life care.